3WZWA

3-isopropylmalate dehydrogenase from shewanella oneidensis mr-1 at 580mpa - complex with ipm and mg
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
364
structure length
364
Chain Sequence
SSYQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKGCEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLRSDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREISRIARIAFEAARGRRKKVTSVDKANVLACSVLWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFDVMLCSNLFGDILSDEIAMLTGSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPIAQILSAALMLRHSLKQEEAASAIERAVTKALNSGYLTGELLSSDQRHKAKTTVQMGDFIADAVKAGV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Pressure Adaptation of 3-Isopropylmalate Dehydrogenase from the Extremely Piezophilic Bacterium Shewanella benthica is Attributed to just One Amino Acid Substitution
rcsb
molecule tags Oxidoreductase
source organism Shewanella oneidensis mr-1
molecule keywords 3-isopropylmalate dehydrogenase
total genus 132
structure length 364
sequence length 364
ec nomenclature ec 1.1.1.85: 3-isopropylmalate dehydrogenase.
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00180 Iso_dh Isocitrate/isopropylmalate dehydrogenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.718.10 Alpha Beta 3-Layer(aba) Sandwich Isopropylmalate Dehydrogenase Isopropylmalate Dehydrogenase 3wzwA00
5GREA 2QFVA 3VL3A 1TYOA 4AJCA 1XADA 3VL2A 3LXYA 5J34A 1LWDA 3WZWA 1PB3A 7ICDA 2HI1A 1CM7A 5GREB 4UMXA 1XACA 1PS7A 4L04A 3UDUA 5HN4A 4UMYA 2UXRA 4AJAA 3VL6A 5L58A 4L03A 1AI3A 5HN6A 2ZTWA 1WPWA 4ICDA 5DE1A 5K11A 1WALA 1IDDA 4JQPA 1GRPA 3UF6A 4IWHA 1IKAA 4JA8A 1AI2A 2E5MA 1V5BA 1IDMA 3FLKA 4YB4A 6ICDA 1PB1A 1IPDA 4AJRA 2QFXA 5LGEA 2QFYA 2Y3ZA 1XKDA 4Y1PA 1GROA 1CW4A 3FMXX 4XXVA 5GRLA 1XABA 1A05A 5ICDA 5GRFA 1YCOA 1HQSA 3VL7A 1V94A 4I3KA 3U9EA 3U1HA 2DHTA 2E0CA 1X0LA 4AOYA 1IDFA 1XGVA 5GRLB 1YXOA 2D4VA 1IDEA 1GC8A 4L06A 3TY3A 5HN5A 1W0DA 3TY4A 3BLXA 3TNGA 5GRFB 5J32A 3VMJA 3VKZA 1CW1A 2Y40A 1XAAA 1VI1A 1GC9A 1U7NA 4XRXA 1ISOA 8ICDA 1DR0A 2AYQA 3BLXB 2Y42A 1HJ6A 2QFWA 1OSJA 3MASA 4F7IA 4ATYA 1OSIA 4HCXA 4AJ3A 1DR8A 4P69C 9ICDA 3BLVA 1G2UA 1VLCA 1R8KA 4AJBA 3MASB 1V53A 1T0LA 3DMSA 3R8WA 2UXQA 1HEXA 3ICDA 3LCBC 5GRHA 3WZXA 3BLVB 1IDCA 5K10A 3MARA 2D1CA 4KZOA 4AOVA 3AH3A 3TSNA 1T09A 3WZVA 2G4OA 5GRHB 3INMA 4XS3A 4AOUA 5I95A 3VMLA 3MAPA 5J33A 1ZORA 3VL4A 5GRIA 1DPZA 1PTMA 4I3LA 5L57A 3VMKA 2IV0A 1PS6A 4WUOA 2Y41A 3WZYA 4AJSA 5I96A 1SJSA 5GRIB 1CW7A 3US8A 3UDOA 1CNZA 4BNPA 5HN3A 1BL5A 1P8FA 3ASJA
chains in the Genus database with same CATH superfamily
5GREA 2QFVA 3VL3A 1TYOA 4AJCA 1XADA 3VL2A 3LXYA 5J34A 1LWDA 3WZWA 1PB3A 7ICDA 2HI1A 1CM7A 5GREB 4UMXA 1XACA 1PS7A 4L04A 3UDUA 5HN4A 4UMYA 2UXRA 4AJAA 3VL6A 5L58A 4L03A 1AI3A 5HN6A 2ZTWA 1WPWA 4ICDA 5DE1A 5K11A 1WALA 1IDDA 4JQPA 1GRPA 3UF6A 4IWHA 1IKAA 4JA8A 1AI2A 2E5MA 1V5BA 1IDMA 3FLKA 4YB4A 6ICDA 1PB1A 1IPDA 4AJRA 2QFXA 5LGEA 2QFYA 2Y3ZA 1XKDA 4Y1PA 1GROA 1CW4A 3FMXX 4XXVA 5GRLA 1XABA 1A05A 5ICDA 5GRFA 1YCOA 1HQSA 3VL7A 1V94A 4I3KA 3U9EA 3U1HA 2DHTA 2E0CA 1X0LA 4AOYA 1IDFA 1XGVA 5GRLB 1YXOA 2D4VA 1IDEA 1GC8A 4L06A 3TY3A 5HN5A 1W0DA 3TY4A 3BLXA 3TNGA 5GRFB 5J32A 3VMJA 3VKZA 1CW1A 2Y40A 1XAAA 1VI1A 1GC9A 1U7NA 4XRXA 1ISOA 8ICDA 1DR0A 2AYQA 3BLXB 2Y42A 1HJ6A 2QFWA 1OSJA 3MASA 4F7IA 4ATYA 1OSIA 4HCXA 4AJ3A 1DR8A 4P69C 9ICDA 3BLVA 1G2UA 1VLCA 1R8KA 4AJBA 3MASB 1V53A 1T0LA 3DMSA 3R8WA 2UXQA 1HEXA 3ICDA 3LCBC 5GRHA 3WZXA 3BLVB 1IDCA 5K10A 3MARA 2D1CA 4KZOA 4AOVA 3AH3A 3TSNA 1T09A 3WZVA 2G4OA 5GRHB 3INMA 4XS3A 4AOUA 5I95A 3VMLA 3MAPA 5J33A 1ZORA 3VL4A 5GRIA 1DPZA 1PTMA 4I3LA 5L57A 3VMKA 2IV0A 1PS6A 4WUOA 2Y41A 3WZYA 4AJSA 5I96A 1SJSA 5GRIB 1CW7A 3US8A 3UDOA 1CNZA 4BNPA 5HN3A 1BL5A 1P8FA 3ASJA
chains in the Genus database with same CATH topology
5GREA 2QFVA 3VL3A 1TYOA 4AJCA 1XADA 3VL2A 3LXYA 5J34A 1LWDA 3WZWA 1PB3A 7ICDA 2HI1A 1CM7A 5GREB 4UMXA 1XACA 1PS7A 4L04A 3UDUA 5HN4A 4UMYA 2UXRA 4AJAA 3VL6A 5L58A 4L03A 1AI3A 5HN6A 2ZTWA 1WPWA 4ICDA 5DE1A 5K11A 1WALA 1IDDA 4JQPA 1GRPA 3UF6A 4IWHA 1IKAA 4JA8A 1AI2A 2E5MA 1V5BA 1IDMA 3FLKA 4YB4A 6ICDA 1PB1A 1IPDA 4AJRA 2QFXA 5LGEA 2QFYA 2Y3ZA 1XKDA 4Y1PA 1GROA 1CW4A 3FMXX 4XXVA 5GRLA 1XABA 1A05A 5ICDA 5GRFA 1YCOA 1HQSA 3VL7A 1V94A 4I3KA 3U9EA 3U1HA 2DHTA 2E0CA 1X0LA 4AOYA 1IDFA 1XGVA 5GRLB 1YXOA 2D4VA 1IDEA 1GC8A 4L06A 3TY3A 5HN5A 1W0DA 3TY4A 3BLXA 3TNGA 5GRFB 5J32A 3VMJA 3VKZA 1CW1A 2Y40A 1XAAA 1VI1A 1GC9A 1U7NA 4XRXA 1ISOA 8ICDA 1DR0A 2AYQA 3BLXB 2Y42A 1HJ6A 2QFWA 1OSJA 3MASA 4F7IA 4ATYA 1OSIA 4HCXA 4AJ3A 1DR8A 4P69C 9ICDA 3BLVA 1G2UA 1VLCA 1R8KA 4AJBA 3MASB 1V53A 1T0LA 3DMSA 3R8WA 2UXQA 1HEXA 3ICDA 3LCBC 5GRHA 3WZXA 3BLVB 1IDCA 5K10A 3MARA 2D1CA 4KZOA 4AOVA 3AH3A 3TSNA 1T09A 3WZVA 2G4OA 5GRHB 3INMA 4XS3A 4AOUA 5I95A 3VMLA 3MAPA 5J33A 1ZORA 3VL4A 5GRIA 1DPZA 1PTMA 4I3LA 5L57A 3VMKA 2IV0A 1PS6A 4WUOA 2Y41A 3WZYA 4AJSA 5I96A 1SJSA 5GRIB 1CW7A 3US8A 3UDOA 1CNZA 4BNPA 5HN3A 1BL5A 1P8FA 3ASJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GRE A;  2QFV A;  3VL3 A;  1TYO A;  4AJC A;  1XAD A;  3VL2 A;  3LXY A;  5J34 A;  1LWD A;  3WZW A;  1PB3 A;  7ICD A;  2HI1 A;  1CM7 A;  5GRE B;  4UMX A;  1XAC A;  1PS7 A;  4L04 A;  3UDU A;  5HN4 A;  4UMY A;  2UXR A;  4AJA A;  3VL6 A;  5L58 A;  4L03 A;  1AI3 A;  5HN6 A;  2ZTW A;  1WPW A;  4ICD A;  5DE1 A;  5K11 A;  1WAL A;  1IDD A;  4JQP A;  1GRP A;  3UF6 A;  4IWH A;  1IKA A;  4JA8 A;  1AI2 A;  2E5M A;  1V5B A;  1IDM A;  3FLK A;  4YB4 A;  6ICD A;  1PB1 A;  1IPD A;  4AJR A;  2QFX A;  5LGE A;  2QFY A;  2Y3Z A;  1XKD A;  4Y1P A;  1GRO A;  1CW4 A;  3FMX X;  4XXV A;  5GRL A;  1XAB A;  1A05 A;  5ICD A;  5GRF A;  1YCO A;  1HQS A;  3VL7 A;  1V94 A;  4I3K A;  3U9E A;  3U1H A;  2DHT A;  2E0C A;  1X0L A;  4AOY A;  1IDF A;  1XGV A;  5GRL B;  1YXO A;  2D4V A;  1IDE A;  1GC8 A;  4L06 A;  3TY3 A;  5HN5 A;  1W0D A;  3TY4 A;  3BLX A;  3TNG A;  5GRF B;  5J32 A;  3VMJ A;  3VKZ A;  1CW1 A;  2Y40 A;  1XAA A;  1VI1 A;  1GC9 A;  1U7N A;  4XRX A;  1ISO A;  8ICD A;  1DR0 A;  2AYQ A;  3BLX B;  2Y42 A;  1HJ6 A;  2QFW A;  1OSJ A;  3MAS A;  4F7I A;  4ATY A;  1OSI A;  4HCX A;  4AJ3 A;  1DR8 A;  4P69 C;  9ICD A;  3BLV A;  1G2U A;  1VLC A;  1R8K A;  4AJB A;  3MAS B;  1V53 A;  1T0L A;  3DMS A;  3R8W A;  2UXQ A;  1HEX A;  3ICD A;  3LCB C;  5GRH A;  3WZX A;  3BLV B;  1IDC A;  5K10 A;  3MAR A;  2D1C A;  4KZO A;  4AOV A;  3AH3 A;  3TSN A;  1T09 A;  3WZV A;  2G4O A;  5GRH B;  3INM A;  4XS3 A;  4AOU A;  5I95 A;  3VML A;  3MAP A;  5J33 A;  1ZOR A;  3VL4 A;  5GRI A;  1DPZ A;  1PTM A;  4I3L A;  5L57 A;  3VMK A;  2IV0 A;  1PS6 A;  4WUO A;  2Y41 A;  3WZY A;  4AJS A;  5I96 A;  1SJS A;  5GRI B;  1CW7 A;  3US8 A;  3UDO A;  1CNZ A;  4BNP A;  5HN3 A;  1BL5 A;  1P8F A;  3ASJ A; 
#chains in the Genus database with same CATH topology
 5GRE A;  2QFV A;  3VL3 A;  1TYO A;  4AJC A;  1XAD A;  3VL2 A;  3LXY A;  5J34 A;  1LWD A;  3WZW A;  1PB3 A;  7ICD A;  2HI1 A;  1CM7 A;  5GRE B;  4UMX A;  1XAC A;  1PS7 A;  4L04 A;  3UDU A;  5HN4 A;  4UMY A;  2UXR A;  4AJA A;  3VL6 A;  5L58 A;  4L03 A;  1AI3 A;  5HN6 A;  2ZTW A;  1WPW A;  4ICD A;  5DE1 A;  5K11 A;  1WAL A;  1IDD A;  4JQP A;  1GRP A;  3UF6 A;  4IWH A;  1IKA A;  4JA8 A;  1AI2 A;  2E5M A;  1V5B A;  1IDM A;  3FLK A;  4YB4 A;  6ICD A;  1PB1 A;  1IPD A;  4AJR A;  2QFX A;  5LGE A;  2QFY A;  2Y3Z A;  1XKD A;  4Y1P A;  1GRO A;  1CW4 A;  3FMX X;  4XXV A;  5GRL A;  1XAB A;  1A05 A;  5ICD A;  5GRF A;  1YCO A;  1HQS A;  3VL7 A;  1V94 A;  4I3K A;  3U9E A;  3U1H A;  2DHT A;  2E0C A;  1X0L A;  4AOY A;  1IDF A;  1XGV A;  5GRL B;  1YXO A;  2D4V A;  1IDE A;  1GC8 A;  4L06 A;  3TY3 A;  5HN5 A;  1W0D A;  3TY4 A;  3BLX A;  3TNG A;  5GRF B;  5J32 A;  3VMJ A;  3VKZ A;  1CW1 A;  2Y40 A;  1XAA A;  1VI1 A;  1GC9 A;  1U7N A;  4XRX A;  1ISO A;  8ICD A;  1DR0 A;  2AYQ A;  3BLX B;  2Y42 A;  1HJ6 A;  2QFW A;  1OSJ A;  3MAS A;  4F7I A;  4ATY A;  1OSI A;  4HCX A;  4AJ3 A;  1DR8 A;  4P69 C;  9ICD A;  3BLV A;  1G2U A;  1VLC A;  1R8K A;  4AJB A;  3MAS B;  1V53 A;  1T0L A;  3DMS A;  3R8W A;  2UXQ A;  1HEX A;  3ICD A;  3LCB C;  5GRH A;  3WZX A;  3BLV B;  1IDC A;  5K10 A;  3MAR A;  2D1C A;  4KZO A;  4AOV A;  3AH3 A;  3TSN A;  1T09 A;  3WZV A;  2G4O A;  5GRH B;  3INM A;  4XS3 A;  4AOU A;  5I95 A;  3VML A;  3MAP A;  5J33 A;  1ZOR A;  3VL4 A;  5GRI A;  1DPZ A;  1PTM A;  4I3L A;  5L57 A;  3VMK A;  2IV0 A;  1PS6 A;  4WUO A;  2Y41 A;  3WZY A;  4AJS A;  5I96 A;  1SJS A;  5GRI B;  1CW7 A;  3US8 A;  3UDO A;  1CNZ A;  4BNP A;  5HN3 A;  1BL5 A;  1P8F A;  3ASJ A; 
#chains in the Genus database with same CATH homology
 5GRE A;  2QFV A;  3VL3 A;  1TYO A;  4AJC A;  1XAD A;  3VL2 A;  3LXY A;  5J34 A;  1LWD A;  3WZW A;  1PB3 A;  7ICD A;  2HI1 A;  1CM7 A;  5GRE B;  4UMX A;  1XAC A;  1PS7 A;  4L04 A;  3UDU A;  5HN4 A;  4UMY A;  2UXR A;  4AJA A;  3VL6 A;  5L58 A;  4L03 A;  1AI3 A;  5HN6 A;  2ZTW A;  1WPW A;  4ICD A;  5DE1 A;  5K11 A;  1WAL A;  1IDD A;  4JQP A;  1GRP A;  3UF6 A;  4IWH A;  1IKA A;  4JA8 A;  1AI2 A;  2E5M A;  1V5B A;  1IDM A;  3FLK A;  4YB4 A;  6ICD A;  1PB1 A;  1IPD A;  4AJR A;  2QFX A;  5LGE A;  2QFY A;  2Y3Z A;  1XKD A;  4Y1P A;  1GRO A;  1CW4 A;  3FMX X;  4XXV A;  5GRL A;  1XAB A;  1A05 A;  5ICD A;  5GRF A;  1YCO A;  1HQS A;  3VL7 A;  1V94 A;  4I3K A;  3U9E A;  3U1H A;  2DHT A;  2E0C A;  1X0L A;  4AOY A;  1IDF A;  1XGV A;  5GRL B;  1YXO A;  2D4V A;  1IDE A;  1GC8 A;  4L06 A;  3TY3 A;  5HN5 A;  1W0D A;  3TY4 A;  3BLX A;  3TNG A;  5GRF B;  5J32 A;  3VMJ A;  3VKZ A;  1CW1 A;  2Y40 A;  1XAA A;  1VI1 A;  1GC9 A;  1U7N A;  4XRX A;  1ISO A;  8ICD A;  1DR0 A;  2AYQ A;  3BLX B;  2Y42 A;  1HJ6 A;  2QFW A;  1OSJ A;  3MAS A;  4F7I A;  4ATY A;  1OSI A;  4HCX A;  4AJ3 A;  1DR8 A;  4P69 C;  9ICD A;  3BLV A;  1G2U A;  1VLC A;  1R8K A;  4AJB A;  3MAS B;  1V53 A;  1T0L A;  3DMS A;  3R8W A;  2UXQ A;  1HEX A;  3ICD A;  3LCB C;  5GRH A;  3WZX A;  3BLV B;  1IDC A;  5K10 A;  3MAR A;  2D1C A;  4KZO A;  4AOV A;  3AH3 A;  3TSN A;  1T09 A;  3WZV A;  2G4O A;  5GRH B;  3INM A;  4XS3 A;  4AOU A;  5I95 A;  3VML A;  3MAP A;  5J33 A;  1ZOR A;  3VL4 A;  5GRI A;  1DPZ A;  1PTM A;  4I3L A;  5L57 A;  3VMK A;  2IV0 A;  1PS6 A;  4WUO A;  2Y41 A;  3WZY A;  4AJS A;  5I96 A;  1SJS A;  5GRI B;  1CW7 A;  3US8 A;  3UDO A;  1CNZ A;  4BNP A;  5HN3 A;  1BL5 A;  1P8F A;  3ASJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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