4BD2A

Bax domain swapped dimer in complex with bidbh3
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
158
structure length
147
Chain Sequence
GGGPTSSEQIMKTGALLLQGFIQDRAGRPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Bax Crystal Structures Reveal How Bh3 Domains Activate Bax and Nucleate its Oligomerization to Induce Apoptosis.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords APOPTOSIS REGULATOR BAX
total genus 60
structure length 147
sequence length 158
ec nomenclature
pdb deposition date 2012-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4bd2A00
1ZY3A 4BD8A 3IHEA 3BL2A 2K7WA 2NLAA 1YSIA 1R2DA 2ME8A 4G35A 1R2GA 2VM6A 3PK1A 2LR1A 4ZEQA 1F16A 1WSXA 4U2UA 4ZIGA 1PQ0A 3IHDA 2O22A 2W3LA 2V6QA 4ZIHA 5IF4A 2XA0A 4ZIIA 4BDUA 3KJ0A 1OHUA 2A5YA 1R2EA 4HW4A 5FDOA 1TY4A 2JCNA 4ZBFA 3MQPA 3CVAX 2JM6B 3IHCA 2VOHA 3DVUA 4MI8A 1MAZA 4S0OA 1BXLA 1K3KA 2O2NA 1G5MA 1DDBA 1PQ1A 3KJ1A 3MK8A 4ZIEA 4S0PA 2NL9A 4U2VA 1YSWA 3QBRA 3WIYA 4BPJA 2YV6A 2XPXA 4QVXA 5KU9A 1LXLA 2IMSA 3IIGA 2VOFA 3I1HA 2VOIA 4HW2A 1GJHA 1O0LA 4BD7A 2MEJA 2KUAA 2WH6A 1AF3A 5FMIA 1R2HA 4OQ6A 4OYDA 3KJ2A 2ABOA 3IO9A 4ZBIA 1G5JA 2IMTA 4BD6A 2MHSA 1Q59A 4K5BC 2O21A 3KZ0A 5FC4A 1MK3A 4QNQA 2ROCA 4BPIA 1YSGA 1YSNA 3IIHA 4YK9A 3ILCA 4ZIFA 2PQKA 4BD2A 2O2FA 5C6HA 2BZWA 2VOGA 4WMRA 2M5BA 2BIDA 5IEZA 1R2IA 5FDRA 5JSBA 2RODA 2O2MA 4B4SA 4HW3A 5C3FA 3D7VA 4YJ4A 2B48A 4OQ5A 5KTGA 3WIXA 2KBWA
chains in the Genus database with same CATH superfamily
1ZY3A 4D2LA 4BD8A 3IHEA 3BL2A 2K7WA 2NLAA 1YSIA 1R2DA 2ME8A 4G35A 1R2GA 2VM6A 3PK1A 2LR1A 4ZEQA 1F16A 1WSXA 2VVWA 4U2UA 2UXEA 4ZIGA 1PQ0A 3IHDA 2JBXA 2O22A 2W3LA 2V6QA 4ZIHA 4M0SA 5IF4A 2XA0A 4ZIIA 4BDUA 3JRVA 1OHUA 3KJ0A 2A5YA 1R2EA 4HW4A 5FDOA 1TY4A 2JCNA 4ZBFA 3MQPA 2K36A 3CVAX 2JM6B 3IHCA 2VOHA 3DVUA 4MI8A 1MAZA 4S0OA 1BXLA 1K3KA 2O2NA 1G5MA 2VVYA 1DDBA 1PQ1A 3KJ1A 3MK8A 4ZIEA 4LQKA 4S0PA 2NL9A 4U2VA 1YSWA 3QBRA 3WIYA 4BPJA 2YV6A 2XPXA 4QVXA 5KU9A 1LXLA 2IMSA 3IIGA 2VOFA 2JBYA 3I1HA 2VOIA 4HW2A 1GJHA 1O0LA 4BD7A 2MEJA 2KUAA 2WH6A 1AF3A 5FMIA 4BBCA 1R2HA 4UF3A 4BBDA 2VVXA 4OQ6A 4OYDA 3KJ2A 4UF2A 2ABOA 3IO9A 4D2MA 4ZBIA 1G5JA 2IMTA 2I39A 4BD6A 2MHSA 1Q59A 4K5BC 2O21A 3KZ0A 5FC4A 1MK3A 4UF1A 2ROCA 4QNQA 4BPIA 1YSGA 2O42A 1YSNA 3IIHA 4YK9A 3ILCA 4ZIFA 2PQKA 4BD2A 2O2FA 5C6HA 2BZWA 2VOGA 4WMRA 2M5BA 2BIDA 5IEZA 1R2IA 5FDRA 5JSBA 2RODA 2O2MA 4B4SA 4HW3A 4BBBA 5C3FA 3D7VA 4YJ4A 2B48A 4OQ5A 5KTGA 2VTYA 2KBWA 3WIXA
chains in the Genus database with same CATH topology
1ZY3A 4BD8A 3IHEA 3BL2A 2K7WA 2NLAA 1YSIA 1R2DA 2ME8A 4G35A 1R2GA 2VM6A 3PK1A 2LR1A 4ZEQA 1F16A 1WSXA 4U2UA 4ZIGA 1PQ0A 3IHDA 2O22A 2W3LA 2V6QA 4ZIHA 5IF4A 2XA0A 4ZIIA 4BDUA 3KJ0A 1OHUA 2A5YA 1R2EA 4HW4A 5FDOA 1TY4A 2JCNA 4ZBFA 3MQPA 3CVAX 2JM6B 3IHCA 2VOHA 3DVUA 4MI8A 1MAZA 4S0OA 1BXLA 1K3KA 2O2NA 1G5MA 1DDBA 1PQ1A 3KJ1A 3MK8A 4ZIEA 4S0PA 2NL9A 4U2VA 1YSWA 3QBRA 3WIYA 4BPJA 2YV6A 2XPXA 4QVXA 5KU9A 1LXLA 2IMSA 3IIGA 2VOFA 3I1HA 2VOIA 4HW2A 1GJHA 1O0LA 4BD7A 2MEJA 2KUAA 2WH6A 1AF3A 5FMIA 1R2HA 4OQ6A 4OYDA 3KJ2A 2ABOA 3IO9A 4ZBIA 1G5JA 2IMTA 4BD6A 2MHSA 1Q59A 4K5BC 2O21A 3KZ0A 5FC4A 1MK3A 4QNQA 2ROCA 4BPIA 1YSGA 1YSNA 3IIHA 4YK9A 3ILCA 4ZIFA 2PQKA 4BD2A 2O2FA 5C6HA 2BZWA 2VOGA 4WMRA 2M5BA 2BIDA 5IEZA 1R2IA 5FDRA 5JSBA 2RODA 2O2MA 4B4SA 4HW3A 5C3FA 3D7VA 4YJ4A 2B48A 4OQ5A 5KTGA 3WIXA 2KBWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ZY3 A;  4BD8 A;  3IHE A;  3BL2 A;  2K7W A;  2NLA A;  1YSI A;  1R2D A;  2ME8 A;  4G35 A;  1R2G A;  2VM6 A;  3PK1 A;  2LR1 A;  4ZEQ A;  1F16 A;  1WSX A;  4U2U A;  4ZIG A;  1PQ0 A;  3IHD A;  2O22 A;  2W3L A;  2V6Q A;  4ZIH A;  5IF4 A;  2XA0 A;  4ZII A;  4BDU A;  3KJ0 A;  1OHU A;  2A5Y A;  1R2E A;  4HW4 A;  5FDO A;  1TY4 A;  2JCN A;  4ZBF A;  3MQP A;  3CVA X;  2JM6 B;  3IHC A;  2VOH A;  3DVU A;  4MI8 A;  1MAZ A;  4S0O A;  1BXL A;  1K3K A;  2O2N A;  1G5M A;  1DDB A;  1PQ1 A;  3KJ1 A;  3MK8 A;  4ZIE A;  4S0P A;  2NL9 A;  4U2V A;  1YSW A;  3QBR A;  3WIY A;  4BPJ A;  2YV6 A;  2XPX A;  4QVX A;  5KU9 A;  1LXL A;  2IMS A;  3IIG A;  2VOF A;  3I1H A;  2VOI A;  4HW2 A;  1GJH A;  1O0L A;  4BD7 A;  2MEJ A;  2KUA A;  2WH6 A;  1AF3 A;  5FMI A;  1R2H A;  4OQ6 A;  4OYD A;  3KJ2 A;  2ABO A;  3IO9 A;  4ZBI A;  1G5J A;  2IMT A;  4BD6 A;  2MHS A;  1Q59 A;  4K5B C;  2O21 A;  3KZ0 A;  5FC4 A;  1MK3 A;  4QNQ A;  2ROC A;  4BPI A;  1YSG A;  1YSN A;  3IIH A;  4YK9 A;  3ILC A;  4ZIF A;  2PQK A;  4BD2 A;  2O2F A;  5C6H A;  2BZW A;  2VOG A;  4WMR A;  2M5B A;  2BID A;  5IEZ A;  1R2I A;  5FDR A;  5JSB A;  2ROD A;  2O2M A;  4B4S A;  4HW3 A;  5C3F A;  3D7V A;  4YJ4 A;  2B48 A;  4OQ5 A;  5KTG A;  3WIX A;  2KBW A; 
#chains in the Genus database with same CATH topology
 1ZY3 A;  4D2L A;  4BD8 A;  3IHE A;  3BL2 A;  2K7W A;  2NLA A;  1YSI A;  1R2D A;  2ME8 A;  4G35 A;  1R2G A;  2VM6 A;  3PK1 A;  2LR1 A;  4ZEQ A;  1F16 A;  1WSX A;  2VVW A;  4U2U A;  2UXE A;  4ZIG A;  1PQ0 A;  3IHD A;  2JBX A;  2O22 A;  2W3L A;  2V6Q A;  4ZIH A;  4M0S A;  5IF4 A;  2XA0 A;  4ZII A;  4BDU A;  3JRV A;  1OHU A;  3KJ0 A;  2A5Y A;  1R2E A;  4HW4 A;  5FDO A;  1TY4 A;  2JCN A;  4ZBF A;  3MQP A;  2K36 A;  3CVA X;  2JM6 B;  3IHC A;  2VOH A;  3DVU A;  4MI8 A;  1MAZ A;  4S0O A;  1BXL A;  1K3K A;  2O2N A;  1G5M A;  2VVY A;  1DDB A;  1PQ1 A;  3KJ1 A;  3MK8 A;  4ZIE A;  4LQK A;  4S0P A;  2NL9 A;  4U2V A;  1YSW A;  3QBR A;  3WIY A;  4BPJ A;  2YV6 A;  2XPX A;  4QVX A;  5KU9 A;  1LXL A;  2IMS A;  3IIG A;  2VOF A;  2JBY A;  3I1H A;  2VOI A;  4HW2 A;  1GJH A;  1O0L A;  4BD7 A;  2MEJ A;  2KUA A;  2WH6 A;  1AF3 A;  5FMI A;  4BBC A;  1R2H A;  4UF3 A;  4BBD A;  2VVX A;  4OQ6 A;  4OYD A;  3KJ2 A;  4UF2 A;  2ABO A;  3IO9 A;  4D2M A;  4ZBI A;  1G5J A;  2IMT A;  2I39 A;  4BD6 A;  2MHS A;  1Q59 A;  4K5B C;  2O21 A;  3KZ0 A;  5FC4 A;  1MK3 A;  4UF1 A;  2ROC A;  4QNQ A;  4BPI A;  1YSG A;  2O42 A;  1YSN A;  3IIH A;  4YK9 A;  3ILC A;  4ZIF A;  2PQK A;  4BD2 A;  2O2F A;  5C6H A;  2BZW A;  2VOG A;  4WMR A;  2M5B A;  2BID A;  5IEZ A;  1R2I A;  5FDR A;  5JSB A;  2ROD A;  2O2M A;  4B4S A;  4HW3 A;  4BBB A;  5C3F A;  3D7V A;  4YJ4 A;  2B48 A;  4OQ5 A;  5KTG A;  2VTY A;  2KBW A;  3WIX A; 
#chains in the Genus database with same CATH homology
 1ZY3 A;  4BD8 A;  3IHE A;  3BL2 A;  2K7W A;  2NLA A;  1YSI A;  1R2D A;  2ME8 A;  4G35 A;  1R2G A;  2VM6 A;  3PK1 A;  2LR1 A;  4ZEQ A;  1F16 A;  1WSX A;  4U2U A;  4ZIG A;  1PQ0 A;  3IHD A;  2O22 A;  2W3L A;  2V6Q A;  4ZIH A;  5IF4 A;  2XA0 A;  4ZII A;  4BDU A;  3KJ0 A;  1OHU A;  2A5Y A;  1R2E A;  4HW4 A;  5FDO A;  1TY4 A;  2JCN A;  4ZBF A;  3MQP A;  3CVA X;  2JM6 B;  3IHC A;  2VOH A;  3DVU A;  4MI8 A;  1MAZ A;  4S0O A;  1BXL A;  1K3K A;  2O2N A;  1G5M A;  1DDB A;  1PQ1 A;  3KJ1 A;  3MK8 A;  4ZIE A;  4S0P A;  2NL9 A;  4U2V A;  1YSW A;  3QBR A;  3WIY A;  4BPJ A;  2YV6 A;  2XPX A;  4QVX A;  5KU9 A;  1LXL A;  2IMS A;  3IIG A;  2VOF A;  3I1H A;  2VOI A;  4HW2 A;  1GJH A;  1O0L A;  4BD7 A;  2MEJ A;  2KUA A;  2WH6 A;  1AF3 A;  5FMI A;  1R2H A;  4OQ6 A;  4OYD A;  3KJ2 A;  2ABO A;  3IO9 A;  4ZBI A;  1G5J A;  2IMT A;  4BD6 A;  2MHS A;  1Q59 A;  4K5B C;  2O21 A;  3KZ0 A;  5FC4 A;  1MK3 A;  4QNQ A;  2ROC A;  4BPI A;  1YSG A;  1YSN A;  3IIH A;  4YK9 A;  3ILC A;  4ZIF A;  2PQK A;  4BD2 A;  2O2F A;  5C6H A;  2BZW A;  2VOG A;  4WMR A;  2M5B A;  2BID A;  5IEZ A;  1R2I A;  5FDR A;  5JSB A;  2ROD A;  2O2M A;  4B4S A;  4HW3 A;  5C3F A;  3D7V A;  4YJ4 A;  2B48 A;  4OQ5 A;  5KTG A;  3WIX A;  2KBW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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