4DFC | Genus

Total Genus 26

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	26
sequence length	123
structure length	121
Chain Sequence	MASTVSQMVDNVLSQPEGKRLMLLAPIIKERKGEHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRLTQRLAESFETALELSGGTAVVADMDDPKAEELLFSAN

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Nucleotide excision repair (NER) machinery recruitment by the transcription-repair coupling factor involves unmasking of a conserved intramolecular interface. pubmed doi rcsb
molecule keywords	Transcription-repair-coupling factor
molecule tags	Hydrolase/dna binding protein
source organism	Escherichia coli
total genus	26
structure length	121
sequence length	123
chains with identical sequence	D
ec nomenclature	ec 3.6.1.3: Adenosinetriphosphatase.
pdb deposition date	2012-01-23

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.190.20	Alpha Beta	2-Layer Sandwich	Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase	Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase	4dfcB00

1DWUA 4QGBA 1CJSA 1U63A 4DFCB 4REOA 3TG8A 1AD2A 3FPNA 3UMYA 2HW8A 1MZPA 4QG3A 4F9TA 3U56A 5DM70 1I2AA 5DM60 3QOYA 4QVIA 3ZQJA 3U4MA 1ZHOA 4LQ4A
chains in the Genus database with same CATH superfamily

2YBVB 1DWUA 1RBOC 2DFXI 3AXKS 1CJSA 1RSCI 4QGBA 1U63A 4DFCB 2VDII 2V69I 1RLCS 8RUCI 1UPPI 4REOA 4F0MB 1WDDS 3TG8A 1AD2A 1BXNI 1RCOC 3FPNA 1IWAB 2VDHI 3UMYA 1EJ7S 1UPMC 2V68I 1RCXC 2V67I 1IR21 1SVDM 1UZHC 2V63I 2HW8A 1GK8I 4F0KB 1RLDS 1MZPA 1IR1S 4QG3A 4F9TA 3U56A 4RUBS 5DM70 2FHZA 4F0HB 3ZXWB 1I2AA 5DM60 3QOYA 4MKVS 2V6AI 4QVIA 3ZQJA 1UW9C 4LQ4A 1RXOC 1UWAC 1UZDC 1RBLI 3RUBS 3U4MA 4HHHS 1BWVS 3AXMS 1ZHOA 1AA1C 1AUSS
chains in the Genus database with same CATH topology

1DWUA 2DFXI 4QGBA 1CJSA 1U63A 4DFCB 4REOA 3TG8A 1AD2A 3FPNA 3UMYA 2HW8A 1MZPA 4QG3A 4F9TA 3U56A 5DM70 2FHZA 1I2AA 5DM60 3QOYA 4QVIA 3ZQJA 3U4MA 1ZHOA 4LQ4A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1DWU A;  4QGB A;  1CJS A;  1U63 A;  4DFC B;  4REO A;  3TG8 A;  1AD2 A;  3FPN A;  3UMY A;  2HW8 A;  1MZP A;  4QG3 A;  4F9T A;  3U56 A;  5DM7 0;  1I2A A;  5DM6 0;  3QOY A;  4QVI A;  3ZQJ A;  3U4M A;  1ZHO A;  4LQ4 A; 
#chains in the Genus database with same CATH topology
 2YBV B;  1DWU A;  1RBO C;  2DFX I;  3AXK S;  1CJS A;  1RSC I;  4QGB A;  1U63 A;  4DFC B;  2VDI I;  2V69 I;  1RLC S;  8RUC I;  1UPP I;  4REO A;  4F0M B;  1WDD S;  3TG8 A;  1AD2 A;  1BXN I;  1RCO C;  3FPN A;  1IWA B;  2VDH I;  3UMY A;  1EJ7 S;  1UPM C;  2V68 I;  1RCX C;  2V67 I;  1IR2 1;  1SVD M;  1UZH C;  2V63 I;  2HW8 A;  1GK8 I;  4F0K B;  1RLD S;  1MZP A;  1IR1 S;  4QG3 A;  4F9T A;  3U56 A;  4RUB S;  5DM7 0;  2FHZ A;  4F0H B;  3ZXW B;  1I2A A;  5DM6 0;  3QOY A;  4MKV S;  2V6A I;  4QVI A;  3ZQJ A;  1UW9 C;  4LQ4 A;  1RXO C;  1UWA C;  1UZD C;  1RBL I;  3RUB S;  3U4M A;  4HHH S;  1BWV S;  3AXM S;  1ZHO A;  1AA1 C;  1AUS S; 
#chains in the Genus database with same CATH homology
 1DWU A;  2DFX I;  4QGB A;  1CJS A;  1U63 A;  4DFC B;  4REO A;  3TG8 A;  1AD2 A;  3FPN A;  3UMY A;  2HW8 A;  1MZP A;  4QG3 A;  4F9T A;  3U56 A;  5DM7 0;  2FHZ A;  1I2A A;  5DM6 0;  3QOY A;  4QVI A;  3ZQJ A;  3U4M A;  1ZHO A;  4LQ4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4DFCB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization