4DU6 | Genus

Total Genus 69

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	69
sequence length	219
structure length	219
Chain Sequence	SSLSKEAELVHQALLARGLETPLRKPELDAETRKTRIQAHMTEVMHLLNLDLTDDSLADTPRRIAKMYVDEIFSGLDYENFPKITLIQNKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILLALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAVRHHG

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 219 atoms

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219 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Crystal structure of GTP cyclohydrolase I from Yersinia pestis complexed with GTP rcsb
molecule keywords	GTP cyclohydrolase 1
molecule tags	Hydrolase
source organism	Yersinia pestis co92
total genus	69
structure length	219
sequence length	219
chains with identical sequence	B, C, D, E
ec nomenclature	ec 3.5.4.16: GTP cyclohydrolase I.
pdb deposition date	2012-02-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01227	GTP_cyclohydroI	GTP cyclohydrolase I

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.286.10	Mainly Alpha	Orthogonal Bundle	GTP Cyclohydrolase I; Chain A, domain 1	GTP Cyclohydrolase I; Chain A, domain 1	4du6A01
3.30.1130.10	Alpha Beta	2-Layer Sandwich	GTP Cyclohydrolase I, domain 2	GTP Cyclohydrolase I, domain 2	4du6A02

3BP1A 1A9CA 1RRIA 1N3TA 1WUQA 3RZPA 1FBXA 3O1KA 3R2EA 1RRWA 1WM9A 1FB1A 1RS4A 2O90A 1GTPA 1Z9WA 3UXVA 3RJ4A 1RSDA 4UQFA 1WURA 4GHMA 5F3MA 1N3SA 4DU6A 1SQLA 4F8BA 1IS7A 2NM3A 3V9OA 4AEYA 1NBUB 1N3RA 1A8RA 1NBUA 4FGCA 1IS8A 1RS2A 1DHNA 4IQIA 2NM2A 2DHNA 1NBUC 1B9LA 5FARA 3S19A 1WPLA 1RRYA 1U68A 2CG8A 1RSIA 3UXJA
chains in the Genus database with same CATH superfamily

1FB1A 1TFEA 2LNZA 1Z9WA 2WSCK 4UQFA 5F3MA 2LO0A 4QPMA 1SQLA 4F8BA 4DRBJ 2NM3A 4FGCA 5DMZA 1AIPC 2NM2A 1NBUC 1B9LA 2O01G 4JA3A 1RRIA 1N3TA 2WSEG 4NE6B 3O1KA 3R2EA 1RS4A 3RJ4A 3VEJA 1RSDA 2KR1A 3BMBA 4DRAE 1IS7A 4NE5B 3V9OA 1NBUB 1N3RA 3LW5K 1NBUA 1EFUB 4R8QA 1EL6A 2DHNA 1WPLA 1RSIA 2WSCG 3UXJA 1WUQA 1FBXA 2WSFK 1RRWA 1WM9A 2P11A 4Q7JA 1WURA 4GHMA 4DU6A 4AEYA 1A8RA 1IS8A 3B0BC 1DHNA 2PN0A 3BP1A 1A9CA 3RZPA 3LW5G 2O90A 1GTPA 3UXVA 4NE3B 1N3SA 2WSEK 4E45B 2WSFG 1RS2A 4IQIA 4E44B 5FARA 3S19A 1RRYA 1U68A 2CG8A
chains in the Genus database with same CATH topology

4JA3A 2PN0A 3BP1A 1A9CA 1RRIA 1N3TA 1WUQA 3RZPA 1FBXA 4NE6B 3O1KA 3R2EA 1RRWA 1WM9A 1FB1A 1RS4A 1TFEA 1GTPA 2P11A 2LNZA 4Q7JA 1Z9WA 2O90A 3UXVA 3RJ4A 3VEJA 1RSDA 2KR1A 1WURA 4UQFA 3BMBA 4NE3B 4GHMA 5F3MA 4DRAE 1N3SA 2LO0A 4QPMA 4DU6A 1SQLA 4DRBJ 4F8BA 1IS7A 4NE5B 2NM3A 3V9OA 4AEYA 4E45B 1NBUB 1N3RA 1A8RA 1NBUA 4FGCA 1EFUB 5DMZA 1IS8A 1RS2A 3B0BC 1AIPC 4R8QA 1DHNA 1EL6A 4IQIA 4E44B 2NM2A 2DHNA 1NBUC 1B9LA 5FARA 3S19A 1WPLA 1RRYA 1U68A 2CG8A 1RSIA 3UXJA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3BP1 A;  1A9C A;  1RRI A;  1N3T A;  1WUQ A;  3RZP A;  1FBX A;  3O1K A;  3R2E A;  1RRW A;  1WM9 A;  1FB1 A;  1RS4 A;  2O90 A;  1GTP A;  1Z9W A;  3UXV A;  3RJ4 A;  1RSD A;  4UQF A;  1WUR A;  4GHM A;  5F3M A;  1N3S A;  4DU6 A;  1SQL A;  4F8B A;  1IS7 A;  2NM3 A;  3V9O A;  4AEY A;  1NBU B;  1N3R A;  1A8R A;  1NBU A;  4FGC A;  1IS8 A;  1RS2 A;  1DHN A;  4IQI A;  2NM2 A;  2DHN A;  1NBU C;  1B9L A;  5FAR A;  3S19 A;  1WPL A;  1RRY A;  1U68 A;  2CG8 A;  1RSI A;  3UXJ A; 
#chains in the Genus database with same CATH topology
 1FB1 A;  1TFE A;  2LNZ A;  1Z9W A;  2WSC K;  4UQF A;  5F3M A;  2LO0 A;  4QPM A;  1SQL A;  4F8B A;  4DRB J;  2NM3 A;  4FGC A;  5DMZ A;  1AIP C;  2NM2 A;  1NBU C;  1B9L A;  2O01 G;  4JA3 A;  1RRI A;  1N3T A;  2WSE G;  4NE6 B;  3O1K A;  3R2E A;  1RS4 A;  3RJ4 A;  3VEJ A;  1RSD A;  2KR1 A;  3BMB A;  4DRA E;  1IS7 A;  4NE5 B;  3V9O A;  1NBU B;  1N3R A;  3LW5 K;  1NBU A;  1EFU B;  4R8Q A;  1EL6 A;  2DHN A;  1WPL A;  1RSI A;  2WSC G;  3UXJ A;  1WUQ A;  1FBX A;  2WSF K;  1RRW A;  1WM9 A;  2P11 A;  4Q7J A;  1WUR A;  4GHM A;  4DU6 A;  4AEY A;  1A8R A;  1IS8 A;  3B0B C;  1DHN A;  2PN0 A;  3BP1 A;  1A9C A;  3RZP A;  3LW5 G;  2O90 A;  1GTP A;  3UXV A;  4NE3 B;  1N3S A;  2WSE K;  4E45 B;  2WSF G;  1RS2 A;  4IQI A;  4E44 B;  5FAR A;  3S19 A;  1RRY A;  1U68 A;  2CG8 A; 
#chains in the Genus database with same CATH homology
 4JA3 A;  2PN0 A;  3BP1 A;  1A9C A;  1RRI A;  1N3T A;  1WUQ A;  3RZP A;  1FBX A;  4NE6 B;  3O1K A;  3R2E A;  1RRW A;  1WM9 A;  1FB1 A;  1RS4 A;  1TFE A;  1GTP A;  2P11 A;  2LNZ A;  4Q7J A;  1Z9W A;  2O90 A;  3UXV A;  3RJ4 A;  3VEJ A;  1RSD A;  2KR1 A;  1WUR A;  4UQF A;  3BMB A;  4NE3 B;  4GHM A;  5F3M A;  4DRA E;  1N3S A;  2LO0 A;  4QPM A;  4DU6 A;  1SQL A;  4DRB J;  4F8B A;  1IS7 A;  4NE5 B;  2NM3 A;  3V9O A;  4AEY A;  4E45 B;  1NBU B;  1N3R A;  1A8R A;  1NBU A;  4FGC A;  1EFU B;  5DMZ A;  1IS8 A;  1RS2 A;  3B0B C;  1AIP C;  4R8Q A;  1DHN A;  1EL6 A;  4IQI A;  4E44 B;  2NM2 A;  2DHN A;  1NBU C;  1B9L A;  5FAR A;  3S19 A;  1WPL A;  1RRY A;  1U68 A;  2CG8 A;  1RSI A;  3UXJ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4DU6A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations