4F7GB

Crystal structure of talin autoinhibition complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
170
structure length
170
Chain Sequence
APGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Cell adhesion
source organism Mus musculus
total genus 73
structure length 170
sequence length 170
ec nomenclature
pdb deposition date 2012-05-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 4f7gB00
2KBBA 4F7GB 2L10A 5FZTA 2L7NA 1SJ7A 2KGXA 1SJ8A 3DYJA 4W8PA 2KVPA 3AY5A 2X0CA 3FYQA
chains in the Genus database with same CATH superfamily
5HWXA 5HXCA 4F7GB 2L10A 2XQYA 2KGXA 4BGOA 4W8PA 3AY5A 5T1DA 4ECGA 2LQUA 5JDGA 3M1CA 5FZTA 3PHF1 5JDHA 5JDMA 5HWYA 1SJ7A 1SJ8A 5HXRA 2KVPA 3PF0A 3WURA 3WSCA 3V5SA 2KBBA 5HYAA 2L7NA 3VJZA 5JDLA 5HXSA 5JDNA 3FYQA 5HXEA 2MTCA 4ONRA 5JDFA 5HXHA 3V5UA 3DYJA 5JDQA 3AT7A 2X0CA
chains in the Genus database with same CATH topology
2KBBA 4F7GB 2L10A 5FZTA 2L7NA 1SJ7A 2KGXA 1SJ8A 3DYJA 4W8PA 2KVPA 3AY5A 2X0CA 3FYQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2KBB A;  4F7G B;  2L10 A;  5FZT A;  2L7N A;  1SJ7 A;  2KGX A;  1SJ8 A;  3DYJ A;  4W8P A;  2KVP A;  3AY5 A;  2X0C A;  3FYQ A; 
#chains in the Genus database with same CATH topology
 5HWX A;  5HXC A;  4F7G B;  2L10 A;  2XQY A;  2KGX A;  4BGO A;  4W8P A;  3AY5 A;  5T1D A;  4ECG A;  2LQU A;  5JDG A;  3M1C A;  5FZT A;  3PHF 1;  5JDH A;  5JDM A;  5HWY A;  1SJ7 A;  1SJ8 A;  5HXR A;  2KVP A;  3PF0 A;  3WUR A;  3WSC A;  3V5S A;  2KBB A;  5HYA A;  2L7N A;  3VJZ A;  5JDL A;  5HXS A;  5JDN A;  3FYQ A;  5HXE A;  2MTC A;  4ONR A;  5JDF A;  5HXH A;  3V5U A;  3DYJ A;  5JDQ A;  3AT7 A;  2X0C A; 
#chains in the Genus database with same CATH homology
 2KBB A;  4F7G B;  2L10 A;  5FZT A;  2L7N A;  1SJ7 A;  2KGX A;  1SJ8 A;  3DYJ A;  4W8P A;  2KVP A;  3AY5 A;  2X0C A;  3FYQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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