4F7GB

Crystal structure of talin autoinhibition complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
170
structure length
170
Chain Sequence
APGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Mus musculus
molecule keywords Talin-1
total genus 73
structure length 170
sequence length 170
ec nomenclature
pdb deposition date 2012-05-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 4f7gB00
4F7GB 1SJ7A 2KGXA 3FYQA 4W8PA 2KVPA 3DYJA 2X0CA 2L10A 3AY5A 5FZTA 2KBBA 2L7NA 1SJ8A
chains in the Genus database with same CATH superfamily
1SJ7A 5JDFA 3AT7A 3M1CA 4BGOA 5HYAA 2LQUA 3AY5A 5HXCA 3WSCA 3VJZA 4F7GB 5HXSA 5HXEA 5JDQA 3WURA 5HXRA 5T1DA 2KBBA 2L7NA 1SJ8A 2X0CA 3PF0A 4ECGA 2KGXA 2XQYA 5JDLA 5JDGA 5JDNA 3PHF1 5HWXA 4ONRA 5JDHA 4W8PA 3FYQA 5JDMA 2KVPA 3V5SA 3V5UA 2L10A 5FZTA 5HWYA 2MTCA 5HXHA 3DYJA
chains in the Genus database with same CATH topology
4F7GB 1SJ7A 2KGXA 3FYQA 4W8PA 2KVPA 3DYJA 2X0CA 2L10A 3AY5A 5FZTA 2KBBA 2L7NA 1SJ8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4F7G B;  1SJ7 A;  2KGX A;  3FYQ A;  4W8P A;  2KVP A;  3DYJ A;  2X0C A;  2L10 A;  3AY5 A;  5FZT A;  2KBB A;  2L7N A;  1SJ8 A; 
#chains in the Genus database with same CATH topology
 1SJ7 A;  5JDF A;  3AT7 A;  3M1C A;  4BGO A;  5HYA A;  2LQU A;  3AY5 A;  5HXC A;  3WSC A;  3VJZ A;  4F7G B;  5HXS A;  5HXE A;  5JDQ A;  3WUR A;  5HXR A;  5T1D A;  2KBB A;  2L7N A;  1SJ8 A;  2X0C A;  3PF0 A;  4ECG A;  2KGX A;  2XQY A;  5JDL A;  5JDG A;  5JDN A;  3PHF 1;  5HWX A;  4ONR A;  5JDH A;  4W8P A;  3FYQ A;  5JDM A;  2KVP A;  3V5S A;  3V5U A;  2L10 A;  5FZT A;  5HWY A;  2MTC A;  5HXH A;  3DYJ A; 
#chains in the Genus database with same CATH homology
 4F7G B;  1SJ7 A;  2KGX A;  3FYQ A;  4W8P A;  2KVP A;  3DYJ A;  2X0C A;  2L10 A;  3AY5 A;  5FZT A;  2KBB A;  2L7N A;  1SJ8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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