4F7GB

Crystal structure of talin autoinhibition complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
170
structure length
170
Chain Sequence
APGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEALHTQMLTAVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNEAASAAGVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion.
pubmed doi rcsb
molecule keywords Talin-1
molecule tags Cell adhesion
source organism Mus musculus
total genus 73
structure length 170
sequence length 170
ec nomenclature
pdb deposition date 2012-05-16
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1420.10 Mainly Alpha Up-down Bundle A middle domain of Talin 1 Talin, central domain 4f7gB00
3DYJA 2KBBA 3AY5A 2L7NA 2X0CA 5FZTA 1SJ7A 2KVPA 4W8PA 3FYQA 4F7GB 2KGXA 1SJ8A 2L10A
chains in the Genus database with same CATH superfamily
2KBBA 2L7NA 5T1DA 4ECGA 2KVPA 3V5SA 3FYQA 4F7GB 5JDGA 3AY5A 5HYAA 5HXEA 5FZTA 5HWYA 4ONRA 4W8PA 3PF0A 2MTCA 5JDNA 3VJZA 5HWXA 5JDFA 3DYJA 3AT7A 2LQUA 5HXSA 2XQYA 2X0CA 3WSCA 3WURA 5HXCA 5JDMA 2L10A 4BGOA 3V5UA 5JDLA 5JDHA 5HXHA 5JDQA 1SJ7A 3PHF1 5HXRA 2KGXA 1SJ8A 3M1CA
chains in the Genus database with same CATH topology
3DYJA 2KBBA 3AY5A 2L7NA 2X0CA 5FZTA 1SJ7A 2KVPA 4W8PA 3FYQA 4F7GB 2KGXA 1SJ8A 2L10A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DYJ A;  2KBB A;  3AY5 A;  2L7N A;  2X0C A;  5FZT A;  1SJ7 A;  2KVP A;  4W8P A;  3FYQ A;  4F7G B;  2KGX A;  1SJ8 A;  2L10 A; 
#chains in the Genus database with same CATH topology
 2KBB A;  2L7N A;  5T1D A;  4ECG A;  2KVP A;  3V5S A;  3FYQ A;  4F7G B;  5JDG A;  3AY5 A;  5HYA A;  5HXE A;  5FZT A;  5HWY A;  4ONR A;  4W8P A;  3PF0 A;  2MTC A;  5JDN A;  3VJZ A;  5HWX A;  5JDF A;  3DYJ A;  3AT7 A;  2LQU A;  5HXS A;  2XQY A;  2X0C A;  3WSC A;  3WUR A;  5HXC A;  5JDM A;  2L10 A;  4BGO A;  3V5U A;  5JDL A;  5JDH A;  5HXH A;  5JDQ A;  1SJ7 A;  3PHF 1;  5HXR A;  2KGX A;  1SJ8 A;  3M1C A; 
#chains in the Genus database with same CATH homology
 3DYJ A;  2KBB A;  3AY5 A;  2L7N A;  2X0C A;  5FZT A;  1SJ7 A;  2KVP A;  4W8P A;  3FYQ A;  4F7G B;  2KGX A;  1SJ8 A;  2L10 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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