4K5BC

Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of bcl-w
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
145
structure length
145
Chain Sequence
PDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEVLVGQVQEWMVAYLETRLADWIHSSGGWAEFTALYG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Co-Crystallization with Conformation-Specific Designed Ankyrin Repeat Proteins Explains the Conformational Flexibility of BCL-W
pubmed doi rcsb
molecule tags Apoptosis
source organism Escherichia coli
molecule keywords Apoptosis regulator BCL-W
total genus 54
structure length 145
sequence length 145
chains with identical sequence D
ec nomenclature
pdb deposition date 2013-04-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
C PF02180 BH4 Bcl-2 homology region 4
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4k5bC00
4ZBFA 1O0LA 2V6QA 3IO9A 5KU9A 1MK3A 3D7VA 1R2EA 3IIHA 1YSWA 5JSBA 2ROCA 1G5JA 1F16A 1R2DA 3ILCA 4HW4A 3PK1A 5FC4A 1PQ0A 1PQ1A 2NL9A 5C3FA 1YSNA 2PQKA 4ZIIA 1R2IA 1TY4A 2O21A 5C6HA 1YSGA 2BZWA 1G5MA 3KZ0A 2JM6B 3WIXA 2VOFA 1Q59A 4YK9A 1MAZA 3BL2A 2RODA 2YV6A 2W3LA 4G35A 5FDRA 2O2FA 4ZIHA 2NLAA 4WMRA 4BDUA 2VOIA 1BXLA 2WH6A 2B48A 2K7WA 2BIDA 2VM6A 2XPXA 3KJ1A 4QNQA 4QVXA 4BD2A 4HW3A 4ZBIA 3WIYA 2O22A 2KBWA 4OQ6A 2M5BA 2VOHA 3KJ2A 1YSIA 4ZIGA 2A5YA 4OQ5A 1OHUA 2ME8A 3MQPA 2MEJA 1WSXA 1DDBA 1AF3A 2VOGA 2ABOA 1K3KA 3IHDA 5IF4A 4ZIFA 5FMIA 1R2HA 3IHCA 2XA0A 3IIGA 4U2UA 4BD6A 4BPJA 2KUAA 4BD8A 1ZY3A 1R2GA 3I1HA 2IMTA 5FDOA 2JCNA 1GJHA 4S0OA 3MK8A 2O2MA 4OYDA 4ZEQA 3IHEA 4U2VA 3CVAX 4S0PA 2LR1A 4BD7A 4BPIA 4YJ4A 2IMSA 2O2NA 3QBRA 4ZIEA 3KJ0A 4B4SA 4K5BC 2MHSA 1LXLA 4HW2A 5IEZA 4MI8A 5KTGA 3DVUA
chains in the Genus database with same CATH superfamily
4ZBFA 1O0LA 2V6QA 2VVYA 3JRVA 3IO9A 5KU9A 1MK3A 3D7VA 1R2EA 3IIHA 1YSWA 5JSBA 2ROCA 1G5JA 2O42A 1F16A 1R2DA 2K36A 3ILCA 4HW4A 3PK1A 5FC4A 1PQ0A 1PQ1A 2NL9A 5C3FA 1YSNA 2PQKA 4ZIIA 1R2IA 1TY4A 2O21A 5C6HA 1YSGA 2BZWA 1G5MA 3KZ0A 2JM6B 3WIXA 2VOFA 1Q59A 4YK9A 1MAZA 4BBBA 2JBXA 3BL2A 4M0SA 2RODA 2YV6A 2W3LA 4G35A 5FDRA 2O2FA 4ZIHA 2NLAA 4WMRA 4BBDA 2VVXA 4BDUA 2VOIA 1BXLA 2WH6A 2B48A 2K7WA 2BIDA 4UF2A 2VM6A 2XPXA 3KJ1A 4QNQA 2JBYA 2UXEA 4QVXA 2I39A 4BD2A 4HW3A 2VTYA 4ZBIA 3WIYA 4UF3A 2O22A 2KBWA 4OQ6A 2M5BA 2VOHA 3KJ2A 4LQKA 1YSIA 4BBCA 4ZIGA 4D2LA 2A5YA 4OQ5A 1OHUA 2ME8A 3MQPA 2MEJA 1WSXA 1DDBA 1AF3A 2VOGA 2ABOA 1K3KA 2VVWA 3IHDA 5IF4A 4ZIFA 5FMIA 1R2HA 3IHCA 2XA0A 3IIGA 4U2UA 4BD6A 4BPJA 2KUAA 4UF1A 1ZY3A 4BD8A 1R2GA 3I1HA 2IMTA 5FDOA 2JCNA 1GJHA 4S0OA 3MK8A 2O2MA 4OYDA 4ZEQA 3IHEA 4U2VA 3CVAX 4S0PA 4D2MA 2LR1A 4BD7A 4BPIA 4YJ4A 2IMSA 2O2NA 3QBRA 4ZIEA 3KJ0A 4B4SA 4K5BC 2MHSA 1LXLA 4HW2A 5IEZA 4MI8A 5KTGA 3DVUA
chains in the Genus database with same CATH topology
4ZBFA 1O0LA 2V6QA 3IO9A 5KU9A 1MK3A 3D7VA 1R2EA 3IIHA 1YSWA 5JSBA 2ROCA 1G5JA 1F16A 1R2DA 3ILCA 4HW4A 3PK1A 5FC4A 1PQ0A 1PQ1A 2NL9A 5C3FA 1YSNA 2PQKA 4ZIIA 1R2IA 1TY4A 2O21A 5C6HA 1YSGA 2BZWA 1G5MA 3KZ0A 2JM6B 3WIXA 2VOFA 1Q59A 4YK9A 1MAZA 3BL2A 2RODA 2YV6A 2W3LA 4G35A 5FDRA 2O2FA 4ZIHA 2NLAA 4WMRA 4BDUA 2VOIA 1BXLA 2WH6A 2B48A 2K7WA 2BIDA 2VM6A 2XPXA 3KJ1A 4QNQA 4QVXA 4BD2A 4HW3A 4ZBIA 3WIYA 2O22A 2KBWA 4OQ6A 2M5BA 2VOHA 3KJ2A 1YSIA 4ZIGA 2A5YA 4OQ5A 1OHUA 2ME8A 3MQPA 2MEJA 1WSXA 1DDBA 1AF3A 2VOGA 2ABOA 1K3KA 3IHDA 5IF4A 4ZIFA 5FMIA 1R2HA 3IHCA 2XA0A 3IIGA 4U2UA 4BD6A 4BPJA 2KUAA 4BD8A 1ZY3A 1R2GA 3I1HA 2IMTA 5FDOA 2JCNA 1GJHA 4S0OA 3MK8A 2O2MA 4OYDA 4ZEQA 3IHEA 4U2VA 3CVAX 4S0PA 2LR1A 4BD7A 4BPIA 4YJ4A 2IMSA 2O2NA 3QBRA 4ZIEA 3KJ0A 4B4SA 4K5BC 2MHSA 1LXLA 4HW2A 5IEZA 4MI8A 5KTGA 3DVUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZBF A;  1O0L A;  2V6Q A;  3IO9 A;  5KU9 A;  1MK3 A;  3D7V A;  1R2E A;  3IIH A;  1YSW A;  5JSB A;  2ROC A;  1G5J A;  1F16 A;  1R2D A;  3ILC A;  4HW4 A;  3PK1 A;  5FC4 A;  1PQ0 A;  1PQ1 A;  2NL9 A;  5C3F A;  1YSN A;  2PQK A;  4ZII A;  1R2I A;  1TY4 A;  2O21 A;  5C6H A;  1YSG A;  2BZW A;  1G5M A;  3KZ0 A;  2JM6 B;  3WIX A;  2VOF A;  1Q59 A;  4YK9 A;  1MAZ A;  3BL2 A;  2ROD A;  2YV6 A;  2W3L A;  4G35 A;  5FDR A;  2O2F A;  4ZIH A;  2NLA A;  4WMR A;  4BDU A;  2VOI A;  1BXL A;  2WH6 A;  2B48 A;  2K7W A;  2BID A;  2VM6 A;  2XPX A;  3KJ1 A;  4QNQ A;  4QVX A;  4BD2 A;  4HW3 A;  4ZBI A;  3WIY A;  2O22 A;  2KBW A;  4OQ6 A;  2M5B A;  2VOH A;  3KJ2 A;  1YSI A;  4ZIG A;  2A5Y A;  4OQ5 A;  1OHU A;  2ME8 A;  3MQP A;  2MEJ A;  1WSX A;  1DDB A;  1AF3 A;  2VOG A;  2ABO A;  1K3K A;  3IHD A;  5IF4 A;  4ZIF A;  5FMI A;  1R2H A;  3IHC A;  2XA0 A;  3IIG A;  4U2U A;  4BD6 A;  4BPJ A;  2KUA A;  4BD8 A;  1ZY3 A;  1R2G A;  3I1H A;  2IMT A;  5FDO A;  2JCN A;  1GJH A;  4S0O A;  3MK8 A;  2O2M A;  4OYD A;  4ZEQ A;  3IHE A;  4U2V A;  3CVA X;  4S0P A;  2LR1 A;  4BD7 A;  4BPI A;  4YJ4 A;  2IMS A;  2O2N A;  3QBR A;  4ZIE A;  3KJ0 A;  4B4S A;  4K5B C;  2MHS A;  1LXL A;  4HW2 A;  5IEZ A;  4MI8 A;  5KTG A;  3DVU A; 
#chains in the Genus database with same CATH topology
 4ZBF A;  1O0L A;  2V6Q A;  2VVY A;  3JRV A;  3IO9 A;  5KU9 A;  1MK3 A;  3D7V A;  1R2E A;  3IIH A;  1YSW A;  5JSB A;  2ROC A;  1G5J A;  2O42 A;  1F16 A;  1R2D A;  2K36 A;  3ILC A;  4HW4 A;  3PK1 A;  5FC4 A;  1PQ0 A;  1PQ1 A;  2NL9 A;  5C3F A;  1YSN A;  2PQK A;  4ZII A;  1R2I A;  1TY4 A;  2O21 A;  5C6H A;  1YSG A;  2BZW A;  1G5M A;  3KZ0 A;  2JM6 B;  3WIX A;  2VOF A;  1Q59 A;  4YK9 A;  1MAZ A;  4BBB A;  2JBX A;  3BL2 A;  4M0S A;  2ROD A;  2YV6 A;  2W3L A;  4G35 A;  5FDR A;  2O2F A;  4ZIH A;  2NLA A;  4WMR A;  4BBD A;  2VVX A;  4BDU A;  2VOI A;  1BXL A;  2WH6 A;  2B48 A;  2K7W A;  2BID A;  4UF2 A;  2VM6 A;  2XPX A;  3KJ1 A;  4QNQ A;  2JBY A;  2UXE A;  4QVX A;  2I39 A;  4BD2 A;  4HW3 A;  2VTY A;  4ZBI A;  3WIY A;  4UF3 A;  2O22 A;  2KBW A;  4OQ6 A;  2M5B A;  2VOH A;  3KJ2 A;  4LQK A;  1YSI A;  4BBC A;  4ZIG A;  4D2L A;  2A5Y A;  4OQ5 A;  1OHU A;  2ME8 A;  3MQP A;  2MEJ A;  1WSX A;  1DDB A;  1AF3 A;  2VOG A;  2ABO A;  1K3K A;  2VVW A;  3IHD A;  5IF4 A;  4ZIF A;  5FMI A;  1R2H A;  3IHC A;  2XA0 A;  3IIG A;  4U2U A;  4BD6 A;  4BPJ A;  2KUA A;  4UF1 A;  1ZY3 A;  4BD8 A;  1R2G A;  3I1H A;  2IMT A;  5FDO A;  2JCN A;  1GJH A;  4S0O A;  3MK8 A;  2O2M A;  4OYD A;  4ZEQ A;  3IHE A;  4U2V A;  3CVA X;  4S0P A;  4D2M A;  2LR1 A;  4BD7 A;  4BPI A;  4YJ4 A;  2IMS A;  2O2N A;  3QBR A;  4ZIE A;  3KJ0 A;  4B4S A;  4K5B C;  2MHS A;  1LXL A;  4HW2 A;  5IEZ A;  4MI8 A;  5KTG A;  3DVU A; 
#chains in the Genus database with same CATH homology
 4ZBF A;  1O0L A;  2V6Q A;  3IO9 A;  5KU9 A;  1MK3 A;  3D7V A;  1R2E A;  3IIH A;  1YSW A;  5JSB A;  2ROC A;  1G5J A;  1F16 A;  1R2D A;  3ILC A;  4HW4 A;  3PK1 A;  5FC4 A;  1PQ0 A;  1PQ1 A;  2NL9 A;  5C3F A;  1YSN A;  2PQK A;  4ZII A;  1R2I A;  1TY4 A;  2O21 A;  5C6H A;  1YSG A;  2BZW A;  1G5M A;  3KZ0 A;  2JM6 B;  3WIX A;  2VOF A;  1Q59 A;  4YK9 A;  1MAZ A;  3BL2 A;  2ROD A;  2YV6 A;  2W3L A;  4G35 A;  5FDR A;  2O2F A;  4ZIH A;  2NLA A;  4WMR A;  4BDU A;  2VOI A;  1BXL A;  2WH6 A;  2B48 A;  2K7W A;  2BID A;  2VM6 A;  2XPX A;  3KJ1 A;  4QNQ A;  4QVX A;  4BD2 A;  4HW3 A;  4ZBI A;  3WIY A;  2O22 A;  2KBW A;  4OQ6 A;  2M5B A;  2VOH A;  3KJ2 A;  1YSI A;  4ZIG A;  2A5Y A;  4OQ5 A;  1OHU A;  2ME8 A;  3MQP A;  2MEJ A;  1WSX A;  1DDB A;  1AF3 A;  2VOG A;  2ABO A;  1K3K A;  3IHD A;  5IF4 A;  4ZIF A;  5FMI A;  1R2H A;  3IHC A;  2XA0 A;  3IIG A;  4U2U A;  4BD6 A;  4BPJ A;  2KUA A;  4BD8 A;  1ZY3 A;  1R2G A;  3I1H A;  2IMT A;  5FDO A;  2JCN A;  1GJH A;  4S0O A;  3MK8 A;  2O2M A;  4OYD A;  4ZEQ A;  3IHE A;  4U2V A;  3CVA X;  4S0P A;  2LR1 A;  4BD7 A;  4BPI A;  4YJ4 A;  2IMS A;  2O2N A;  3QBR A;  4ZIE A;  3KJ0 A;  4B4S A;  4K5B C;  2MHS A;  1LXL A;  4HW2 A;  5IEZ A;  4MI8 A;  5KTG A;  3DVU A; 
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