4K8U | Genus

Total Genus 39

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	39
sequence length	178
structure length	178
Chain Sequence	ELQELRRELEELSVGSDGVLIWKIGSYGRRLQEAKAKPNLECFSPAFYTHKYGYKLQVSAFLNGNGSGEGTHLSLYIRVLPGAFDNLLEWPFARRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQDIRKRNYVRDDAVFIRAAVELPRKI

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 178 atoms

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178 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structure of the TRAF4 TRAF domain with a coiled-coil domain and its implications for the TRAF4 signalling pathway doi rcsb
molecule keywords	TNF receptor-associated factor 4
total genus	39
structure length	178
sequence length	178
chains with identical sequence	B, C
ec nomenclature
pdb deposition date	2013-04-18

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.210.10	Mainly Beta	Sandwich	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	4k8uA00

1YZEA 3IVVA 1D01A 4GHUA 3HQMA 1L0AA 1YY6A 3IVQA 2CR2A 1LB6A 1FLLA 1LB5A 2F1YA 1CA4A 4JJQA 4KG9A 2FOPA 1KZZA 1RF3A 4CA1A 1LB4A 1FLKA 4I7CA 3HQLA 3HU6A 4X3GA 4GWMA 1K2FA 1CA9A 5E1TA 2F1WA 2GKWA 3IVBA 2F1ZA 3ZJBA 4I7DA 4M4EA 1QSCA 3HQIA 4GJHA 1D0AA 3HQHA 2AN6A 4GWNA 5H9MA 2XXNA 4Z8MA 1CZZA 2FOJA 4YSIA 3MQSC 4O1VA 3MQRA 4I7BA 1ZMSA 1D0JA 2A25A 2F1XA 1CZYA 3HSVA 4K8UA 2FOOA 4C9ZA 1D00A 1F3VB
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1YZE A;  3IVV A;  1D01 A;  4GHU A;  3HQM A;  1L0A A;  1YY6 A;  3IVQ A;  2CR2 A;  1LB6 A;  1FLL A;  1LB5 A;  2F1Y A;  1CA4 A;  4JJQ A;  4KG9 A;  2FOP A;  1KZZ A;  1RF3 A;  4CA1 A;  1LB4 A;  1FLK A;  4I7C A;  3HQL A;  3HU6 A;  4X3G A;  4GWM A;  1K2F A;  1CA9 A;  5E1T A;  2F1W A;  2GKW A;  3IVB A;  2F1Z A;  3ZJB A;  4I7D A;  4M4E A;  1QSC A;  3HQI A;  4GJH A;  1D0A A;  3HQH A;  2AN6 A;  4GWN A;  5H9M A;  2XXN A;  4Z8M A;  1CZZ A;  2FOJ A;  4YSI A;  3MQS C;  4O1V A;  3MQR A;  4I7B A;  1ZMS A;  1D0J A;  2A25 A;  2F1X A;  1CZY A;  3HSV A;  4K8U A;  2FOO A;  4C9Z A;  1D00 A;  1F3V B; 
#chains in the Genus database with same CATH topology
 1YZE A;  3IVV A;  1D01 A;  4GHU A;  3HQM A;  1L0A A;  1YY6 A;  3IVQ A;  2CR2 A;  1LB6 A;  1FLL A;  1LB5 A;  2F1Y A;  1CA4 A;  4JJQ A;  4KG9 A;  2FOP A;  1KZZ A;  1RF3 A;  4CA1 A;  1LB4 A;  1FLK A;  4I7C A;  3HQL A;  3HU6 A;  4X3G A;  4GWM A;  1K2F A;  1CA9 A;  5E1T A;  2F1W A;  2GKW A;  3IVB A;  2F1Z A;  3ZJB A;  4I7D A;  4M4E A;  1QSC A;  3HQI A;  4GJH A;  1D0A A;  3HQH A;  2AN6 A;  4GWN A;  5H9M A;  2XXN A;  4Z8M A;  1CZZ A;  2FOJ A;  4YSI A;  3MQS C;  4O1V A;  3MQR A;  4I7B A;  1ZMS A;  1D0J A;  2A25 A;  2F1X A;  1CZY A;  3HSV A;  4K8U A;  2FOO A;  4C9Z A;  1D00 A;  1F3V B; 
#chains in the Genus database with same CATH homology
 1YZE A;  3IVV A;  1D01 A;  4GHU A;  3HQM A;  1L0A A;  1YY6 A;  3IVQ A;  2CR2 A;  1LB6 A;  1FLL A;  1LB5 A;  2F1Y A;  1CA4 A;  4JJQ A;  4KG9 A;  2FOP A;  1KZZ A;  1RF3 A;  4CA1 A;  1LB4 A;  1FLK A;  4I7C A;  3HQL A;  3HU6 A;  4X3G A;  4GWM A;  1K2F A;  1CA9 A;  5E1T A;  2F1W A;  2GKW A;  3IVB A;  2F1Z A;  3ZJB A;  4I7D A;  4M4E A;  1QSC A;  3HQI A;  4GJH A;  1D0A A;  3HQH A;  2AN6 A;  4GWN A;  5H9M A;  2XXN A;  4Z8M A;  1CZZ A;  2FOJ A;  4YSI A;  3MQS C;  4O1V A;  3MQR A;  4I7B A;  1ZMS A;  1D0J A;  2A25 A;  2F1X A;  1CZY A;  3HSV A;  4K8U A;  2FOO A;  4C9Z A;  1D00 A;  1F3V B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4K8UA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization