4Z8M | Genus

Total Genus 29

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	29
sequence length	152
structure length	152
Chain Sequence	NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 152 atoms

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152 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Ligase/signaling protein
source organism	Homo sapiens
publication title	Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling pubmed doi rcsb
molecule keywords	TNF receptor-associated factor 6
total genus	29
structure length	152
sequence length	152
chains with identical sequence	B
ec nomenclature	ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date	2015-04-09

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.210.10	Mainly Beta	Sandwich	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	4z8mA00

1LB6A 3IVBA 1D0JA 1F3VB 2FOOA 2A25A 3HQIA 2F1XA 4GHUA 4GWMA 4K8UA 3MQRA 1YY6A 1QSCA 2F1WA 5E1TA 2F1ZA 1LB4A 1LB5A 3HQMA 1D0AA 4I7BA 1YZEA 1D01A 4X3GA 4Z8MA 4GWNA 4I7DA 3HQHA 4I7CA 3HSVA 1CZZA 4GJHA 1FLLA 1KZZA 2AN6A 3HQLA 2FOPA 3IVQA 1CA4A 4KG9A 4O1VA 4CA1A 1CZYA 1FLKA 3HU6A 1K2FA 4YSIA 3IVVA 1RF3A 1ZMSA 1CA9A 2GKWA 2CR2A 4M4EA 3ZJBA 2XXNA 1L0AA 4C9ZA 4JJQA 2FOJA 1D00A 3MQSC 5H9MA 2F1YA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 1LB6 A;  3IVB A;  1D0J A;  1F3V B;  2FOO A;  2A25 A;  3HQI A;  2F1X A;  4GHU A;  4GWM A;  4K8U A;  3MQR A;  1YY6 A;  1QSC A;  2F1W A;  5E1T A;  2F1Z A;  1LB4 A;  1LB5 A;  3HQM A;  1D0A A;  4I7B A;  1YZE A;  1D01 A;  4X3G A;  4Z8M A;  4GWN A;  4I7D A;  3HQH A;  4I7C A;  3HSV A;  1CZZ A;  4GJH A;  1FLL A;  1KZZ A;  2AN6 A;  3HQL A;  2FOP A;  3IVQ A;  1CA4 A;  4KG9 A;  4O1V A;  4CA1 A;  1CZY A;  1FLK A;  3HU6 A;  1K2F A;  4YSI A;  3IVV A;  1RF3 A;  1ZMS A;  1CA9 A;  2GKW A;  2CR2 A;  4M4E A;  3ZJB A;  2XXN A;  1L0A A;  4C9Z A;  4JJQ A;  2FOJ A;  1D00 A;  3MQS C;  5H9M A;  2F1Y A; 
#chains in the Genus database with same CATH topology
 1LB6 A;  3IVB A;  1D0J A;  1F3V B;  2FOO A;  2A25 A;  3HQI A;  2F1X A;  4GHU A;  4GWM A;  4K8U A;  3MQR A;  1YY6 A;  1QSC A;  2F1W A;  5E1T A;  2F1Z A;  1LB4 A;  1LB5 A;  3HQM A;  1D0A A;  4I7B A;  1YZE A;  1D01 A;  4X3G A;  4Z8M A;  4GWN A;  4I7D A;  3HQH A;  4I7C A;  3HSV A;  1CZZ A;  4GJH A;  1FLL A;  1KZZ A;  2AN6 A;  3HQL A;  2FOP A;  3IVQ A;  1CA4 A;  4KG9 A;  4O1V A;  4CA1 A;  1CZY A;  1FLK A;  3HU6 A;  1K2F A;  4YSI A;  3IVV A;  1RF3 A;  1ZMS A;  1CA9 A;  2GKW A;  2CR2 A;  4M4E A;  3ZJB A;  2XXN A;  1L0A A;  4C9Z A;  4JJQ A;  2FOJ A;  1D00 A;  3MQS C;  5H9M A;  2F1Y A; 
#chains in the Genus database with same CATH homology
 1LB6 A;  3IVB A;  1D0J A;  1F3V B;  2FOO A;  2A25 A;  3HQI A;  2F1X A;  4GHU A;  4GWM A;  4K8U A;  3MQR A;  1YY6 A;  1QSC A;  2F1W A;  5E1T A;  2F1Z A;  1LB4 A;  1LB5 A;  3HQM A;  1D0A A;  4I7B A;  1YZE A;  1D01 A;  4X3G A;  4Z8M A;  4GWN A;  4I7D A;  3HQH A;  4I7C A;  3HSV A;  1CZZ A;  4GJH A;  1FLL A;  1KZZ A;  2AN6 A;  3HQL A;  2FOP A;  3IVQ A;  1CA4 A;  4KG9 A;  4O1V A;  4CA1 A;  1CZY A;  1FLK A;  3HU6 A;  1K2F A;  4YSI A;  3IVV A;  1RF3 A;  1ZMS A;  1CA9 A;  2GKW A;  2CR2 A;  4M4E A;  3ZJB A;  2XXN A;  1L0A A;  4C9Z A;  4JJQ A;  2FOJ A;  1D00 A;  3MQS C;  5H9M A;  2F1Y A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4Z8MA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization