4Z8MA

Crystal structure of the mavs-traf6 complex
Total Genus 29
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
29
sequence length
152
structure length
152
Chain Sequence
NGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVST
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Insights into Mitochondrial Antiviral Signaling Protein (MAVS)-Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Signaling
pubmed doi rcsb
molecule tags Ligase/signaling protein
source organism Homo sapiens
molecule keywords TNF receptor-associated factor 6
total genus 29
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2015-04-09
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 4z8mA00
4GJHA 2F1YA 2F1WA 3IVVA 1CA4A 2CR2A 3IVQA 4I7BA 1YZEA 1FLLA 2F1ZA 2XXNA 3IVBA 3ZJBA 1QSCA 3HQIA 1D00A 3HQHA 3MQSC 4C9ZA 1K2FA 1D0JA 4JJQA 2A25A 4YSIA 1KZZA 5H9MA 4CA1A 1RF3A 1LB4A 1F3VB 2FOOA 3HU6A 2GKWA 3MQRA 1L0AA 4KG9A 3HQMA 1CZYA 1D0AA 1FLKA 3HSVA 2FOPA 4GWNA 4I7DA 4K8UA 1ZMSA 1LB6A 4GHUA 5E1TA 1YY6A 1LB5A 2F1XA 3HQLA 1CZZA 4X3GA 4Z8MA 1CA9A 1D01A 4M4EA 2FOJA 4I7CA 4GWMA 4O1VA 2AN6A
chains in the Genus database with same CATH superfamily
4GJHA 2F1YA 2F1WA 3IVVA 1CA4A 2CR2A 3IVQA 4I7BA 1YZEA 1FLLA 2F1ZA 2XXNA 3IVBA 3ZJBA 1QSCA 3HQIA 1D00A 3HQHA 3MQSC 4C9ZA 1K2FA 1D0JA 4JJQA 2A25A 4YSIA 1KZZA 5H9MA 4CA1A 1RF3A 1LB4A 1F3VB 2FOOA 3HU6A 2GKWA 3MQRA 1L0AA 4KG9A 3HQMA 1CZYA 1D0AA 1FLKA 3HSVA 2FOPA 4GWNA 4I7DA 4K8UA 1ZMSA 1LB6A 4GHUA 5E1TA 1YY6A 1LB5A 2F1XA 3HQLA 1CZZA 4X3GA 4Z8MA 1CA9A 1D01A 4M4EA 2FOJA 4I7CA 4GWMA 4O1VA 2AN6A
chains in the Genus database with same CATH topology
4GJHA 2F1YA 2F1WA 3IVVA 1CA4A 2CR2A 3IVQA 4I7BA 1YZEA 1FLLA 2F1ZA 2XXNA 3IVBA 3ZJBA 1QSCA 3HQIA 1D00A 3HQHA 3MQSC 4C9ZA 1K2FA 1D0JA 4JJQA 2A25A 4YSIA 1KZZA 5H9MA 4CA1A 1RF3A 1LB4A 1F3VB 2FOOA 3HU6A 2GKWA 3MQRA 1L0AA 4KG9A 3HQMA 1CZYA 1D0AA 1FLKA 3HSVA 2FOPA 4GWNA 4I7DA 4K8UA 1ZMSA 1LB6A 4GHUA 5E1TA 1YY6A 1LB5A 2F1XA 3HQLA 1CZZA 4X3GA 4Z8MA 1CA9A 1D01A 4M4EA 2FOJA 4I7CA 4GWMA 4O1VA 2AN6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GJH A;  2F1Y A;  2F1W A;  3IVV A;  1CA4 A;  2CR2 A;  3IVQ A;  4I7B A;  1YZE A;  1FLL A;  2F1Z A;  2XXN A;  3IVB A;  3ZJB A;  1QSC A;  3HQI A;  1D00 A;  3HQH A;  3MQS C;  4C9Z A;  1K2F A;  1D0J A;  4JJQ A;  2A25 A;  4YSI A;  1KZZ A;  5H9M A;  4CA1 A;  1RF3 A;  1LB4 A;  1F3V B;  2FOO A;  3HU6 A;  2GKW A;  3MQR A;  1L0A A;  4KG9 A;  3HQM A;  1CZY A;  1D0A A;  1FLK A;  3HSV A;  2FOP A;  4GWN A;  4I7D A;  4K8U A;  1ZMS A;  1LB6 A;  4GHU A;  5E1T A;  1YY6 A;  1LB5 A;  2F1X A;  3HQL A;  1CZZ A;  4X3G A;  4Z8M A;  1CA9 A;  1D01 A;  4M4E A;  2FOJ A;  4I7C A;  4GWM A;  4O1V A;  2AN6 A; 
#chains in the Genus database with same CATH topology
 4GJH A;  2F1Y A;  2F1W A;  3IVV A;  1CA4 A;  2CR2 A;  3IVQ A;  4I7B A;  1YZE A;  1FLL A;  2F1Z A;  2XXN A;  3IVB A;  3ZJB A;  1QSC A;  3HQI A;  1D00 A;  3HQH A;  3MQS C;  4C9Z A;  1K2F A;  1D0J A;  4JJQ A;  2A25 A;  4YSI A;  1KZZ A;  5H9M A;  4CA1 A;  1RF3 A;  1LB4 A;  1F3V B;  2FOO A;  3HU6 A;  2GKW A;  3MQR A;  1L0A A;  4KG9 A;  3HQM A;  1CZY A;  1D0A A;  1FLK A;  3HSV A;  2FOP A;  4GWN A;  4I7D A;  4K8U A;  1ZMS A;  1LB6 A;  4GHU A;  5E1T A;  1YY6 A;  1LB5 A;  2F1X A;  3HQL A;  1CZZ A;  4X3G A;  4Z8M A;  1CA9 A;  1D01 A;  4M4E A;  2FOJ A;  4I7C A;  4GWM A;  4O1V A;  2AN6 A; 
#chains in the Genus database with same CATH homology
 4GJH A;  2F1Y A;  2F1W A;  3IVV A;  1CA4 A;  2CR2 A;  3IVQ A;  4I7B A;  1YZE A;  1FLL A;  2F1Z A;  2XXN A;  3IVB A;  3ZJB A;  1QSC A;  3HQI A;  1D00 A;  3HQH A;  3MQS C;  4C9Z A;  1K2F A;  1D0J A;  4JJQ A;  2A25 A;  4YSI A;  1KZZ A;  5H9M A;  4CA1 A;  1RF3 A;  1LB4 A;  1F3V B;  2FOO A;  3HU6 A;  2GKW A;  3MQR A;  1L0A A;  4KG9 A;  3HQM A;  1CZY A;  1D0A A;  1FLK A;  3HSV A;  2FOP A;  4GWN A;  4I7D A;  4K8U A;  1ZMS A;  1LB6 A;  4GHU A;  5E1T A;  1YY6 A;  1LB5 A;  2F1X A;  3HQL A;  1CZZ A;  4X3G A;  4Z8M A;  1CA9 A;  1D01 A;  4M4E A;  2FOJ A;  4I7C A;  4GWM A;  4O1V A;  2AN6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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