4ZIEA

Crystal structure of core/latch dimer of bax in complex with bimbh3
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
158
structure length
147
Chain Sequence
GGGPTSSEQIMKTGALLLQGFIQDRALDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptosis regulator BAX
total genus 60
structure length 147
sequence length 158
ec nomenclature
pdb deposition date 2015-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4zieA00
1O0LA 2NL9A 1R2IA 1AF3A 2VOGA 2VOHA 1R2DA 2O21A 4BD2A 4MI8A 5C3FA 4ZEQA 1PQ1A 1WSXA 2RODA 4BD7A 4S0OA 3BL2A 2ABOA 3MQPA 2M5BA 3IHDA 4ZIFA 4OQ6A 1G5MA 3I1HA 2KBWA 5JSBA 2NLAA 3IHEA 1YSGA 2WH6A 4BDUA 1R2HA 3KZ0A 4G35A 4BD6A 4YK9A 2ROCA 4QVXA 2O2NA 5FDRA 2MEJA 4ZIHA 1TY4A 4ZIEA 3IO9A 4HW2A 1ZY3A 5IF4A 2JM6B 2W3LA 2BZWA 2A5YA 3PK1A 2XPXA 4U2UA 3WIYA 5C6HA 4OYDA 4B4SA 1MAZA 2BIDA 1R2GA 2KUAA 1YSWA 2MHSA 3ILCA 3QBRA 5KTGA 1Q59A 1DDBA 5FC4A 1G5JA 3IIGA 2O22A 3KJ2A 5KU9A 1BXLA 1PQ0A 1F16A 2B48A 4HW3A 2ME8A 2YV6A 1LXLA 1K3KA 1YSIA 1MK3A 4WMRA 2IMSA 2VM6A 4ZBFA 2O2FA 4HW4A 2XA0A 2IMTA 1OHUA 3DVUA 4BPIA 2VOFA 4BPJA 3IIHA 3WIXA 3KJ0A 1GJHA 4OQ5A 2LR1A 4S0PA 5FMIA 4U2VA 1R2EA 5FDOA 3D7VA 3IHCA 3KJ1A 2K7WA 3CVAX 4K5BC 2PQKA 4ZBIA 4ZIGA 2O2MA 4YJ4A 1YSNA 2V6QA 2VOIA 2JCNA 4ZIIA 3MK8A 5IEZA 4QNQA 4BD8A
chains in the Genus database with same CATH superfamily
1O0LA 2NL9A 4BBBA 1R2IA 1AF3A 2VOGA 2VOHA 2UXEA 1R2DA 2O21A 4BD2A 4MI8A 5C3FA 4ZEQA 1PQ1A 1WSXA 2RODA 4BD7A 4S0OA 3BL2A 2ABOA 3MQPA 2M5BA 2JBXA 3IHDA 4ZIFA 4OQ6A 1G5MA 3I1HA 2KBWA 5JSBA 2NLAA 3IHEA 1YSGA 2WH6A 4BDUA 1R2HA 3KZ0A 4G35A 4BD6A 4YK9A 2ROCA 4QVXA 2O2NA 5FDRA 2MEJA 4UF1A 4ZIHA 1TY4A 4ZIEA 3IO9A 4HW2A 4BBDA 1ZY3A 5IF4A 2JM6B 2W3LA 2BZWA 2A5YA 3PK1A 2XPXA 2I39A 2O42A 4U2UA 3WIYA 5C6HA 4OYDA 2VVWA 4B4SA 1MAZA 3JRVA 4D2MA 2BIDA 1R2GA 4LQKA 2KUAA 4UF2A 1YSWA 2MHSA 3ILCA 3QBRA 5KTGA 1Q59A 1DDBA 5FC4A 1G5JA 3IIGA 2O22A 3KJ2A 5KU9A 1BXLA 2VTYA 1PQ0A 1F16A 2B48A 4D2LA 4HW3A 2JBYA 2K36A 2ME8A 2YV6A 1LXLA 1K3KA 1YSIA 1MK3A 4WMRA 2IMSA 2VM6A 2VVXA 4ZBFA 2O2FA 4HW4A 2XA0A 4BBCA 2IMTA 1OHUA 3DVUA 4BPIA 2VOFA 4UF3A 4BPJA 2VVYA 3IIHA 3WIXA 3KJ0A 1GJHA 4OQ5A 2LR1A 4S0PA 5FMIA 4U2VA 1R2EA 5FDOA 3D7VA 3IHCA 3KJ1A 2K7WA 3CVAX 4K5BC 2PQKA 4ZBIA 4ZIGA 2O2MA 4YJ4A 1YSNA 2V6QA 2VOIA 2JCNA 4ZIIA 3MK8A 5IEZA 4M0SA 4QNQA 4BD8A
chains in the Genus database with same CATH topology
1O0LA 2NL9A 1R2IA 1AF3A 2VOGA 2VOHA 1R2DA 2O21A 4BD2A 4MI8A 5C3FA 4ZEQA 1PQ1A 1WSXA 2RODA 4BD7A 4S0OA 3BL2A 2ABOA 3MQPA 2M5BA 3IHDA 4ZIFA 4OQ6A 1G5MA 3I1HA 2KBWA 5JSBA 2NLAA 3IHEA 1YSGA 2WH6A 4BDUA 1R2HA 3KZ0A 4G35A 4BD6A 4YK9A 2ROCA 4QVXA 2O2NA 5FDRA 2MEJA 4ZIHA 1TY4A 4ZIEA 3IO9A 4HW2A 1ZY3A 5IF4A 2JM6B 2W3LA 2BZWA 2A5YA 3PK1A 2XPXA 4U2UA 3WIYA 5C6HA 4OYDA 4B4SA 1MAZA 2BIDA 1R2GA 2KUAA 1YSWA 2MHSA 3ILCA 3QBRA 5KTGA 1Q59A 1DDBA 5FC4A 1G5JA 3IIGA 2O22A 3KJ2A 5KU9A 1BXLA 1PQ0A 1F16A 2B48A 4HW3A 2ME8A 2YV6A 1LXLA 1K3KA 1YSIA 1MK3A 4WMRA 2IMSA 2VM6A 4ZBFA 2O2FA 4HW4A 2XA0A 2IMTA 1OHUA 3DVUA 4BPIA 2VOFA 4BPJA 3IIHA 3WIXA 3KJ0A 1GJHA 4OQ5A 2LR1A 4S0PA 5FMIA 4U2VA 1R2EA 5FDOA 3D7VA 3IHCA 3KJ1A 2K7WA 3CVAX 4K5BC 2PQKA 4ZBIA 4ZIGA 2O2MA 4YJ4A 1YSNA 2V6QA 2VOIA 2JCNA 4ZIIA 3MK8A 5IEZA 4QNQA 4BD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1O0L A;  2NL9 A;  1R2I A;  1AF3 A;  2VOG A;  2VOH A;  1R2D A;  2O21 A;  4BD2 A;  4MI8 A;  5C3F A;  4ZEQ A;  1PQ1 A;  1WSX A;  2ROD A;  4BD7 A;  4S0O A;  3BL2 A;  2ABO A;  3MQP A;  2M5B A;  3IHD A;  4ZIF A;  4OQ6 A;  1G5M A;  3I1H A;  2KBW A;  5JSB A;  2NLA A;  3IHE A;  1YSG A;  2WH6 A;  4BDU A;  1R2H A;  3KZ0 A;  4G35 A;  4BD6 A;  4YK9 A;  2ROC A;  4QVX A;  2O2N A;  5FDR A;  2MEJ A;  4ZIH A;  1TY4 A;  4ZIE A;  3IO9 A;  4HW2 A;  1ZY3 A;  5IF4 A;  2JM6 B;  2W3L A;  2BZW A;  2A5Y A;  3PK1 A;  2XPX A;  4U2U A;  3WIY A;  5C6H A;  4OYD A;  4B4S A;  1MAZ A;  2BID A;  1R2G A;  2KUA A;  1YSW A;  2MHS A;  3ILC A;  3QBR A;  5KTG A;  1Q59 A;  1DDB A;  5FC4 A;  1G5J A;  3IIG A;  2O22 A;  3KJ2 A;  5KU9 A;  1BXL A;  1PQ0 A;  1F16 A;  2B48 A;  4HW3 A;  2ME8 A;  2YV6 A;  1LXL A;  1K3K A;  1YSI A;  1MK3 A;  4WMR A;  2IMS A;  2VM6 A;  4ZBF A;  2O2F A;  4HW4 A;  2XA0 A;  2IMT A;  1OHU A;  3DVU A;  4BPI A;  2VOF A;  4BPJ A;  3IIH A;  3WIX A;  3KJ0 A;  1GJH A;  4OQ5 A;  2LR1 A;  4S0P A;  5FMI A;  4U2V A;  1R2E A;  5FDO A;  3D7V A;  3IHC A;  3KJ1 A;  2K7W A;  3CVA X;  4K5B C;  2PQK A;  4ZBI A;  4ZIG A;  2O2M A;  4YJ4 A;  1YSN A;  2V6Q A;  2VOI A;  2JCN A;  4ZII A;  3MK8 A;  5IEZ A;  4QNQ A;  4BD8 A; 
#chains in the Genus database with same CATH topology
 1O0L A;  2NL9 A;  4BBB A;  1R2I A;  1AF3 A;  2VOG A;  2VOH A;  2UXE A;  1R2D A;  2O21 A;  4BD2 A;  4MI8 A;  5C3F A;  4ZEQ A;  1PQ1 A;  1WSX A;  2ROD A;  4BD7 A;  4S0O A;  3BL2 A;  2ABO A;  3MQP A;  2M5B A;  2JBX A;  3IHD A;  4ZIF A;  4OQ6 A;  1G5M A;  3I1H A;  2KBW A;  5JSB A;  2NLA A;  3IHE A;  1YSG A;  2WH6 A;  4BDU A;  1R2H A;  3KZ0 A;  4G35 A;  4BD6 A;  4YK9 A;  2ROC A;  4QVX A;  2O2N A;  5FDR A;  2MEJ A;  4UF1 A;  4ZIH A;  1TY4 A;  4ZIE A;  3IO9 A;  4HW2 A;  4BBD A;  1ZY3 A;  5IF4 A;  2JM6 B;  2W3L A;  2BZW A;  2A5Y A;  3PK1 A;  2XPX A;  2I39 A;  2O42 A;  4U2U A;  3WIY A;  5C6H A;  4OYD A;  2VVW A;  4B4S A;  1MAZ A;  3JRV A;  4D2M A;  2BID A;  1R2G A;  4LQK A;  2KUA A;  4UF2 A;  1YSW A;  2MHS A;  3ILC A;  3QBR A;  5KTG A;  1Q59 A;  1DDB A;  5FC4 A;  1G5J A;  3IIG A;  2O22 A;  3KJ2 A;  5KU9 A;  1BXL A;  2VTY A;  1PQ0 A;  1F16 A;  2B48 A;  4D2L A;  4HW3 A;  2JBY A;  2K36 A;  2ME8 A;  2YV6 A;  1LXL A;  1K3K A;  1YSI A;  1MK3 A;  4WMR A;  2IMS A;  2VM6 A;  2VVX A;  4ZBF A;  2O2F A;  4HW4 A;  2XA0 A;  4BBC A;  2IMT A;  1OHU A;  3DVU A;  4BPI A;  2VOF A;  4UF3 A;  4BPJ A;  2VVY A;  3IIH A;  3WIX A;  3KJ0 A;  1GJH A;  4OQ5 A;  2LR1 A;  4S0P A;  5FMI A;  4U2V A;  1R2E A;  5FDO A;  3D7V A;  3IHC A;  3KJ1 A;  2K7W A;  3CVA X;  4K5B C;  2PQK A;  4ZBI A;  4ZIG A;  2O2M A;  4YJ4 A;  1YSN A;  2V6Q A;  2VOI A;  2JCN A;  4ZII A;  3MK8 A;  5IEZ A;  4M0S A;  4QNQ A;  4BD8 A; 
#chains in the Genus database with same CATH homology
 1O0L A;  2NL9 A;  1R2I A;  1AF3 A;  2VOG A;  2VOH A;  1R2D A;  2O21 A;  4BD2 A;  4MI8 A;  5C3F A;  4ZEQ A;  1PQ1 A;  1WSX A;  2ROD A;  4BD7 A;  4S0O A;  3BL2 A;  2ABO A;  3MQP A;  2M5B A;  3IHD A;  4ZIF A;  4OQ6 A;  1G5M A;  3I1H A;  2KBW A;  5JSB A;  2NLA A;  3IHE A;  1YSG A;  2WH6 A;  4BDU A;  1R2H A;  3KZ0 A;  4G35 A;  4BD6 A;  4YK9 A;  2ROC A;  4QVX A;  2O2N A;  5FDR A;  2MEJ A;  4ZIH A;  1TY4 A;  4ZIE A;  3IO9 A;  4HW2 A;  1ZY3 A;  5IF4 A;  2JM6 B;  2W3L A;  2BZW A;  2A5Y A;  3PK1 A;  2XPX A;  4U2U A;  3WIY A;  5C6H A;  4OYD A;  4B4S A;  1MAZ A;  2BID A;  1R2G A;  2KUA A;  1YSW A;  2MHS A;  3ILC A;  3QBR A;  5KTG A;  1Q59 A;  1DDB A;  5FC4 A;  1G5J A;  3IIG A;  2O22 A;  3KJ2 A;  5KU9 A;  1BXL A;  1PQ0 A;  1F16 A;  2B48 A;  4HW3 A;  2ME8 A;  2YV6 A;  1LXL A;  1K3K A;  1YSI A;  1MK3 A;  4WMR A;  2IMS A;  2VM6 A;  4ZBF A;  2O2F A;  4HW4 A;  2XA0 A;  2IMT A;  1OHU A;  3DVU A;  4BPI A;  2VOF A;  4BPJ A;  3IIH A;  3WIX A;  3KJ0 A;  1GJH A;  4OQ5 A;  2LR1 A;  4S0P A;  5FMI A;  4U2V A;  1R2E A;  5FDO A;  3D7V A;  3IHC A;  3KJ1 A;  2K7W A;  3CVA X;  4K5B C;  2PQK A;  4ZBI A;  4ZIG A;  2O2M A;  4YJ4 A;  1YSN A;  2V6Q A;  2VOI A;  2JCN A;  4ZII A;  3MK8 A;  5IEZ A;  4QNQ A;  4BD8 A; 
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