4ZIFA

Crystal structure of core/latch dimer of bax in complex with bimbh3mini
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
156
structure length
146
Chain Sequence
GGPTSSEQIMKTGALLLQGFIQDRAGRDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptosis regulator BAX
total genus 56
structure length 146
sequence length 156
ec nomenclature
pdb deposition date 2015-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4zifA00
4BDUA 3IIGA 1YSIA 3KJ1A 4ZEQA 3BL2A 3ILCA 2BZWA 4OQ6A 2ABOA 4B4SA 1WSXA 2KBWA 3DVUA 4U2VA 5IF4A 5KTGA 4YK9A 4S0OA 3WIYA 1TY4A 4ZIGA 4ZBIA 1OHUA 3D7VA 2NL9A 3QBRA 2VOIA 2B48A 2W3LA 2XA0A 2XPXA 4BPIA 4S0PA 5FDRA 1LXLA 2VOFA 1YSNA 3IHEA 4HW4A 3KZ0A 4U2UA 2IMTA 5IEZA 5KU9A 2A5YA 1G5MA 3IO9A 2BIDA 2M5BA 2RODA 1DDBA 2JCNA 4QNQA 5FMIA 5FDOA 1YSWA 2VOHA 4BD8A 1MAZA 2O22A 4MI8A 2IMSA 2NLAA 5JSBA 1PQ1A 3IIHA 1R2DA 2O21A 5C3FA 2LR1A 3MK8A 1AF3A 2KUAA 1Q59A 4K5BC 2O2FA 4HW2A 1BXLA 3CVAX 4BD6A 2JM6B 3IHDA 4ZBFA 1R2IA 3WIXA 2VOGA 2O2MA 2VM6A 4HW3A 4BD7A 4BPJA 1YSGA 5FC4A 2ME8A 4G35A 1O0LA 4QVXA 2ROCA 3PK1A 4ZIFA 5C6HA 4ZIEA 2WH6A 1R2EA 2YV6A 3KJ2A 2MHSA 2MEJA 2V6QA 4OYDA 4ZIHA 1MK3A 1PQ0A 1ZY3A 2O2NA 3IHCA 2K7WA 3KJ0A 4ZIIA 4OQ5A 4BD2A 2PQKA 3I1HA 1K3KA 1R2HA 1R2GA 1GJHA 1F16A 1G5JA 4WMRA 4YJ4A 3MQPA
chains in the Genus database with same CATH superfamily
4BDUA 3IIGA 1YSIA 3KJ1A 4ZEQA 3BL2A 3ILCA 2BZWA 4OQ6A 2ABOA 4B4SA 1WSXA 2KBWA 4UF3A 3DVUA 4U2VA 2I39A 5IF4A 5KTGA 2O42A 4YK9A 4S0OA 3WIYA 1TY4A 4ZIGA 2UXEA 4ZBIA 1OHUA 3D7VA 2NL9A 3QBRA 2VOIA 2B48A 2W3LA 2XA0A 2XPXA 4BBCA 4BPIA 4S0PA 5FDRA 4UF2A 1LXLA 2VOFA 1YSNA 3IHEA 4HW4A 3KZ0A 4BBBA 4U2UA 2IMTA 5IEZA 5KU9A 2A5YA 1G5MA 3IO9A 2BIDA 2M5BA 2RODA 4D2MA 2VVWA 1DDBA 2JCNA 4QNQA 2JBXA 5FMIA 2JBYA 5FDOA 1YSWA 2VOHA 4BD8A 1MAZA 2O22A 4MI8A 2IMSA 2NLAA 5JSBA 1PQ1A 4BBDA 3IIHA 1R2DA 2O21A 5C3FA 2LR1A 4D2LA 3MK8A 1AF3A 2KUAA 1Q59A 4K5BC 2O2FA 4HW2A 1BXLA 3CVAX 4BD6A 2JM6B 3IHDA 4ZBFA 1R2IA 3WIXA 2VOGA 4LQKA 2O2MA 2VM6A 4HW3A 4BD7A 4BPJA 1YSGA 2K36A 2ME8A 3JRVA 1O0LA 4G35A 4M0SA 4QVXA 5FC4A 2VVYA 2ROCA 3PK1A 2VVXA 4ZIFA 5C6HA 4ZIEA 2WH6A 1R2EA 4UF1A 2YV6A 3KJ2A 2MHSA 2MEJA 2V6QA 4OYDA 4ZIHA 1MK3A 1PQ0A 1ZY3A 2O2NA 3IHCA 2K7WA 2VTYA 3KJ0A 4ZIIA 4OQ5A 4BD2A 2PQKA 3I1HA 1K3KA 1R2HA 1R2GA 1GJHA 1F16A 1G5JA 4WMRA 4YJ4A 3MQPA
chains in the Genus database with same CATH topology
4BDUA 3IIGA 1YSIA 3KJ1A 4ZEQA 3BL2A 3ILCA 2BZWA 4OQ6A 2ABOA 4B4SA 1WSXA 2KBWA 3DVUA 4U2VA 5IF4A 5KTGA 4YK9A 4S0OA 3WIYA 1TY4A 4ZIGA 4ZBIA 1OHUA 3D7VA 2NL9A 3QBRA 2VOIA 2B48A 2W3LA 2XA0A 2XPXA 4BPIA 4S0PA 5FDRA 1LXLA 2VOFA 1YSNA 3IHEA 4HW4A 3KZ0A 4U2UA 2IMTA 5IEZA 5KU9A 2A5YA 1G5MA 3IO9A 2BIDA 2M5BA 2RODA 1DDBA 2JCNA 4QNQA 5FMIA 5FDOA 1YSWA 2VOHA 4BD8A 1MAZA 2O22A 4MI8A 2IMSA 2NLAA 5JSBA 1PQ1A 3IIHA 1R2DA 2O21A 5C3FA 2LR1A 3MK8A 1AF3A 2KUAA 1Q59A 4K5BC 2O2FA 4HW2A 1BXLA 3CVAX 4BD6A 2JM6B 3IHDA 4ZBFA 1R2IA 3WIXA 2VOGA 2O2MA 2VM6A 4HW3A 4BD7A 4BPJA 1YSGA 5FC4A 2ME8A 4G35A 1O0LA 4QVXA 2ROCA 3PK1A 4ZIFA 5C6HA 4ZIEA 2WH6A 1R2EA 2YV6A 3KJ2A 2MHSA 2MEJA 2V6QA 4OYDA 4ZIHA 1MK3A 1PQ0A 1ZY3A 2O2NA 3IHCA 2K7WA 3KJ0A 4ZIIA 4OQ5A 4BD2A 2PQKA 3I1HA 1K3KA 1R2HA 1R2GA 1GJHA 1F16A 1G5JA 4WMRA 4YJ4A 3MQPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BDU A;  3IIG A;  1YSI A;  3KJ1 A;  4ZEQ A;  3BL2 A;  3ILC A;  2BZW A;  4OQ6 A;  2ABO A;  4B4S A;  1WSX A;  2KBW A;  3DVU A;  4U2V A;  5IF4 A;  5KTG A;  4YK9 A;  4S0O A;  3WIY A;  1TY4 A;  4ZIG A;  4ZBI A;  1OHU A;  3D7V A;  2NL9 A;  3QBR A;  2VOI A;  2B48 A;  2W3L A;  2XA0 A;  2XPX A;  4BPI A;  4S0P A;  5FDR A;  1LXL A;  2VOF A;  1YSN A;  3IHE A;  4HW4 A;  3KZ0 A;  4U2U A;  2IMT A;  5IEZ A;  5KU9 A;  2A5Y A;  1G5M A;  3IO9 A;  2BID A;  2M5B A;  2ROD A;  1DDB A;  2JCN A;  4QNQ A;  5FMI A;  5FDO A;  1YSW A;  2VOH A;  4BD8 A;  1MAZ A;  2O22 A;  4MI8 A;  2IMS A;  2NLA A;  5JSB A;  1PQ1 A;  3IIH A;  1R2D A;  2O21 A;  5C3F A;  2LR1 A;  3MK8 A;  1AF3 A;  2KUA A;  1Q59 A;  4K5B C;  2O2F A;  4HW2 A;  1BXL A;  3CVA X;  4BD6 A;  2JM6 B;  3IHD A;  4ZBF A;  1R2I A;  3WIX A;  2VOG A;  2O2M A;  2VM6 A;  4HW3 A;  4BD7 A;  4BPJ A;  1YSG A;  5FC4 A;  2ME8 A;  4G35 A;  1O0L A;  4QVX A;  2ROC A;  3PK1 A;  4ZIF A;  5C6H A;  4ZIE A;  2WH6 A;  1R2E A;  2YV6 A;  3KJ2 A;  2MHS A;  2MEJ A;  2V6Q A;  4OYD A;  4ZIH A;  1MK3 A;  1PQ0 A;  1ZY3 A;  2O2N A;  3IHC A;  2K7W A;  3KJ0 A;  4ZII A;  4OQ5 A;  4BD2 A;  2PQK A;  3I1H A;  1K3K A;  1R2H A;  1R2G A;  1GJH A;  1F16 A;  1G5J A;  4WMR A;  4YJ4 A;  3MQP A; 
#chains in the Genus database with same CATH topology
 4BDU A;  3IIG A;  1YSI A;  3KJ1 A;  4ZEQ A;  3BL2 A;  3ILC A;  2BZW A;  4OQ6 A;  2ABO A;  4B4S A;  1WSX A;  2KBW A;  4UF3 A;  3DVU A;  4U2V A;  2I39 A;  5IF4 A;  5KTG A;  2O42 A;  4YK9 A;  4S0O A;  3WIY A;  1TY4 A;  4ZIG A;  2UXE A;  4ZBI A;  1OHU A;  3D7V A;  2NL9 A;  3QBR A;  2VOI A;  2B48 A;  2W3L A;  2XA0 A;  2XPX A;  4BBC A;  4BPI A;  4S0P A;  5FDR A;  4UF2 A;  1LXL A;  2VOF A;  1YSN A;  3IHE A;  4HW4 A;  3KZ0 A;  4BBB A;  4U2U A;  2IMT A;  5IEZ A;  5KU9 A;  2A5Y A;  1G5M A;  3IO9 A;  2BID A;  2M5B A;  2ROD A;  4D2M A;  2VVW A;  1DDB A;  2JCN A;  4QNQ A;  2JBX A;  5FMI A;  2JBY A;  5FDO A;  1YSW A;  2VOH A;  4BD8 A;  1MAZ A;  2O22 A;  4MI8 A;  2IMS A;  2NLA A;  5JSB A;  1PQ1 A;  4BBD A;  3IIH A;  1R2D A;  2O21 A;  5C3F A;  2LR1 A;  4D2L A;  3MK8 A;  1AF3 A;  2KUA A;  1Q59 A;  4K5B C;  2O2F A;  4HW2 A;  1BXL A;  3CVA X;  4BD6 A;  2JM6 B;  3IHD A;  4ZBF A;  1R2I A;  3WIX A;  2VOG A;  4LQK A;  2O2M A;  2VM6 A;  4HW3 A;  4BD7 A;  4BPJ A;  1YSG A;  2K36 A;  2ME8 A;  3JRV A;  1O0L A;  4G35 A;  4M0S A;  4QVX A;  5FC4 A;  2VVY A;  2ROC A;  3PK1 A;  2VVX A;  4ZIF A;  5C6H A;  4ZIE A;  2WH6 A;  1R2E A;  4UF1 A;  2YV6 A;  3KJ2 A;  2MHS A;  2MEJ A;  2V6Q A;  4OYD A;  4ZIH A;  1MK3 A;  1PQ0 A;  1ZY3 A;  2O2N A;  3IHC A;  2K7W A;  2VTY A;  3KJ0 A;  4ZII A;  4OQ5 A;  4BD2 A;  2PQK A;  3I1H A;  1K3K A;  1R2H A;  1R2G A;  1GJH A;  1F16 A;  1G5J A;  4WMR A;  4YJ4 A;  3MQP A; 
#chains in the Genus database with same CATH homology
 4BDU A;  3IIG A;  1YSI A;  3KJ1 A;  4ZEQ A;  3BL2 A;  3ILC A;  2BZW A;  4OQ6 A;  2ABO A;  4B4S A;  1WSX A;  2KBW A;  3DVU A;  4U2V A;  5IF4 A;  5KTG A;  4YK9 A;  4S0O A;  3WIY A;  1TY4 A;  4ZIG A;  4ZBI A;  1OHU A;  3D7V A;  2NL9 A;  3QBR A;  2VOI A;  2B48 A;  2W3L A;  2XA0 A;  2XPX A;  4BPI A;  4S0P A;  5FDR A;  1LXL A;  2VOF A;  1YSN A;  3IHE A;  4HW4 A;  3KZ0 A;  4U2U A;  2IMT A;  5IEZ A;  5KU9 A;  2A5Y A;  1G5M A;  3IO9 A;  2BID A;  2M5B A;  2ROD A;  1DDB A;  2JCN A;  4QNQ A;  5FMI A;  5FDO A;  1YSW A;  2VOH A;  4BD8 A;  1MAZ A;  2O22 A;  4MI8 A;  2IMS A;  2NLA A;  5JSB A;  1PQ1 A;  3IIH A;  1R2D A;  2O21 A;  5C3F A;  2LR1 A;  3MK8 A;  1AF3 A;  2KUA A;  1Q59 A;  4K5B C;  2O2F A;  4HW2 A;  1BXL A;  3CVA X;  4BD6 A;  2JM6 B;  3IHD A;  4ZBF A;  1R2I A;  3WIX A;  2VOG A;  2O2M A;  2VM6 A;  4HW3 A;  4BD7 A;  4BPJ A;  1YSG A;  5FC4 A;  2ME8 A;  4G35 A;  1O0L A;  4QVX A;  2ROC A;  3PK1 A;  4ZIF A;  5C6H A;  4ZIE A;  2WH6 A;  1R2E A;  2YV6 A;  3KJ2 A;  2MHS A;  2MEJ A;  2V6Q A;  4OYD A;  4ZIH A;  1MK3 A;  1PQ0 A;  1ZY3 A;  2O2N A;  3IHC A;  2K7W A;  3KJ0 A;  4ZII A;  4OQ5 A;  4BD2 A;  2PQK A;  3I1H A;  1K3K A;  1R2H A;  1R2G A;  1GJH A;  1F16 A;  1G5J A;  4WMR A;  4YJ4 A;  3MQP A; 
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similar chains in the Genus database (?% sequence similarity)
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