4ZIFA

Crystal structure of core/latch dimer of bax in complex with bimbh3mini
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
156
structure length
146
Chain Sequence
GGPTSSEQIMKTGALLLQGFIQDRAGRDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptosis regulator BAX
total genus 56
structure length 146
sequence length 156
ec nomenclature
pdb deposition date 2015-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4zifA00
1TY4A 4ZIEA 1OHUA 1R2GA 2O2NA 5KTGA 3IHCA 3KZ0A 1LXLA 3KJ0A 2BIDA 3IIHA 2NLAA 1Q59A 2VM6A 4HW3A 2ROCA 2IMTA 5FMIA 3CVAX 1BXLA 3BL2A 3KJ1A 2O2MA 5FDRA 4BDUA 5C6HA 4BD7A 2VOHA 2MEJA 2A5YA 2NL9A 3IO9A 1R2EA 4OQ6A 2JCNA 2IMSA 3ILCA 4ZEQA 4BD6A 1ZY3A 2O21A 2MHSA 3I1HA 4ZBIA 4ZIIA 3IHDA 1YSIA 1YSNA 3IIGA 4BPIA 4ZBFA 2K7WA 5IEZA 2W3LA 5C3FA 2XPXA 2RODA 1MK3A 3DVUA 1GJHA 2VOGA 3WIYA 2O2FA 3IHEA 2ABOA 2XA0A 1R2IA 4U2VA 1R2DA 2M5BA 4QVXA 4BD2A 1R2HA 4HW4A 4OQ5A 1YSWA 2BZWA 2O22A 4G35A 4BPJA 4OYDA 3MK8A 2ME8A 1O0LA 2VOIA 1PQ0A 1DDBA 5JSBA 4HW2A 4ZIHA 2VOFA 2YV6A 4YJ4A 3QBRA 1WSXA 4BD8A 5IF4A 3WIXA 2LR1A 2PQKA 4ZIFA 4ZIGA 3PK1A 4S0PA 1F16A 1G5MA 3D7VA 1YSGA 3MQPA 4WMRA 4YK9A 4B4SA 4QNQA 4K5BC 1G5JA 5FC4A 4S0OA 2KBWA 5KU9A 5FDOA 1K3KA 1PQ1A 2WH6A 1MAZA 4U2UA 2B48A 2JM6B 1AF3A 2V6QA 3KJ2A 2KUAA 4MI8A
chains in the Genus database with same CATH superfamily
1TY4A 4ZIEA 1OHUA 4BBCA 1R2GA 2O2NA 5KTGA 3IHCA 3KZ0A 1LXLA 3KJ0A 2BIDA 3IIHA 2NLAA 1Q59A 2VM6A 4HW3A 4UF3A 2ROCA 2IMTA 5FMIA 2UXEA 3CVAX 1BXLA 2O42A 3BL2A 2I39A 3KJ1A 2O2MA 5FDRA 4BDUA 5C6HA 4BD7A 2VOHA 2MEJA 2A5YA 2NL9A 3IO9A 1R2EA 4OQ6A 2JCNA 2IMSA 3ILCA 4ZEQA 2VVYA 4BD6A 1ZY3A 2O21A 2MHSA 3I1HA 4ZBIA 4ZIIA 3IHDA 1YSIA 1YSNA 3IIGA 4BPIA 4ZBFA 2K7WA 5IEZA 2W3LA 5C3FA 2XPXA 2RODA 1MK3A 3DVUA 1GJHA 2VOGA 3WIYA 2VVXA 2JBYA 2O2FA 3IHEA 2ABOA 2XA0A 1R2IA 4U2VA 1R2DA 2M5BA 4QVXA 3JRVA 4BD2A 2JBXA 2VTYA 1R2HA 4HW4A 4M0SA 4OQ5A 1YSWA 2BZWA 4BBBA 2O22A 4G35A 4BPJA 4OYDA 4D2MA 3MK8A 2ME8A 1O0LA 2VOIA 1PQ0A 4UF2A 4LQKA 1DDBA 5JSBA 4HW2A 4UF1A 4ZIHA 2VOFA 2VVWA 2YV6A 4YJ4A 3QBRA 1WSXA 4BD8A 5IF4A 2K36A 3WIXA 2LR1A 2PQKA 4ZIFA 4ZIGA 3PK1A 4S0PA 1F16A 1G5MA 3D7VA 1YSGA 4D2LA 3MQPA 4WMRA 4YK9A 4B4SA 4QNQA 4K5BC 1G5JA 5FC4A 4S0OA 2KBWA 5KU9A 5FDOA 1K3KA 1PQ1A 2WH6A 1MAZA 4U2UA 2B48A 4BBDA 2JM6B 1AF3A 2V6QA 3KJ2A 2KUAA 4MI8A
chains in the Genus database with same CATH topology
1TY4A 4ZIEA 1OHUA 1R2GA 2O2NA 5KTGA 3IHCA 3KZ0A 1LXLA 3KJ0A 2BIDA 3IIHA 2NLAA 1Q59A 2VM6A 4HW3A 2ROCA 2IMTA 5FMIA 3CVAX 1BXLA 3BL2A 3KJ1A 2O2MA 5FDRA 4BDUA 5C6HA 4BD7A 2VOHA 2MEJA 2A5YA 2NL9A 3IO9A 1R2EA 4OQ6A 2JCNA 2IMSA 3ILCA 4ZEQA 4BD6A 1ZY3A 2O21A 2MHSA 3I1HA 4ZBIA 4ZIIA 3IHDA 1YSIA 1YSNA 3IIGA 4BPIA 4ZBFA 2K7WA 5IEZA 2W3LA 5C3FA 2XPXA 2RODA 1MK3A 3DVUA 1GJHA 2VOGA 3WIYA 2O2FA 3IHEA 2ABOA 2XA0A 1R2IA 4U2VA 1R2DA 2M5BA 4QVXA 4BD2A 1R2HA 4HW4A 4OQ5A 1YSWA 2BZWA 2O22A 4G35A 4BPJA 4OYDA 3MK8A 2ME8A 1O0LA 2VOIA 1PQ0A 1DDBA 5JSBA 4HW2A 4ZIHA 2VOFA 2YV6A 4YJ4A 3QBRA 1WSXA 4BD8A 5IF4A 3WIXA 2LR1A 2PQKA 4ZIFA 4ZIGA 3PK1A 4S0PA 1F16A 1G5MA 3D7VA 1YSGA 3MQPA 4WMRA 4YK9A 4B4SA 4QNQA 4K5BC 1G5JA 5FC4A 4S0OA 2KBWA 5KU9A 5FDOA 1K3KA 1PQ1A 2WH6A 1MAZA 4U2UA 2B48A 2JM6B 1AF3A 2V6QA 3KJ2A 2KUAA 4MI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TY4 A;  4ZIE A;  1OHU A;  1R2G A;  2O2N A;  5KTG A;  3IHC A;  3KZ0 A;  1LXL A;  3KJ0 A;  2BID A;  3IIH A;  2NLA A;  1Q59 A;  2VM6 A;  4HW3 A;  2ROC A;  2IMT A;  5FMI A;  3CVA X;  1BXL A;  3BL2 A;  3KJ1 A;  2O2M A;  5FDR A;  4BDU A;  5C6H A;  4BD7 A;  2VOH A;  2MEJ A;  2A5Y A;  2NL9 A;  3IO9 A;  1R2E A;  4OQ6 A;  2JCN A;  2IMS A;  3ILC A;  4ZEQ A;  4BD6 A;  1ZY3 A;  2O21 A;  2MHS A;  3I1H A;  4ZBI A;  4ZII A;  3IHD A;  1YSI A;  1YSN A;  3IIG A;  4BPI A;  4ZBF A;  2K7W A;  5IEZ A;  2W3L A;  5C3F A;  2XPX A;  2ROD A;  1MK3 A;  3DVU A;  1GJH A;  2VOG A;  3WIY A;  2O2F A;  3IHE A;  2ABO A;  2XA0 A;  1R2I A;  4U2V A;  1R2D A;  2M5B A;  4QVX A;  4BD2 A;  1R2H A;  4HW4 A;  4OQ5 A;  1YSW A;  2BZW A;  2O22 A;  4G35 A;  4BPJ A;  4OYD A;  3MK8 A;  2ME8 A;  1O0L A;  2VOI A;  1PQ0 A;  1DDB A;  5JSB A;  4HW2 A;  4ZIH A;  2VOF A;  2YV6 A;  4YJ4 A;  3QBR A;  1WSX A;  4BD8 A;  5IF4 A;  3WIX A;  2LR1 A;  2PQK A;  4ZIF A;  4ZIG A;  3PK1 A;  4S0P A;  1F16 A;  1G5M A;  3D7V A;  1YSG A;  3MQP A;  4WMR A;  4YK9 A;  4B4S A;  4QNQ A;  4K5B C;  1G5J A;  5FC4 A;  4S0O A;  2KBW A;  5KU9 A;  5FDO A;  1K3K A;  1PQ1 A;  2WH6 A;  1MAZ A;  4U2U A;  2B48 A;  2JM6 B;  1AF3 A;  2V6Q A;  3KJ2 A;  2KUA A;  4MI8 A; 
#chains in the Genus database with same CATH topology
 1TY4 A;  4ZIE A;  1OHU A;  4BBC A;  1R2G A;  2O2N A;  5KTG A;  3IHC A;  3KZ0 A;  1LXL A;  3KJ0 A;  2BID A;  3IIH A;  2NLA A;  1Q59 A;  2VM6 A;  4HW3 A;  4UF3 A;  2ROC A;  2IMT A;  5FMI A;  2UXE A;  3CVA X;  1BXL A;  2O42 A;  3BL2 A;  2I39 A;  3KJ1 A;  2O2M A;  5FDR A;  4BDU A;  5C6H A;  4BD7 A;  2VOH A;  2MEJ A;  2A5Y A;  2NL9 A;  3IO9 A;  1R2E A;  4OQ6 A;  2JCN A;  2IMS A;  3ILC A;  4ZEQ A;  2VVY A;  4BD6 A;  1ZY3 A;  2O21 A;  2MHS A;  3I1H A;  4ZBI A;  4ZII A;  3IHD A;  1YSI A;  1YSN A;  3IIG A;  4BPI A;  4ZBF A;  2K7W A;  5IEZ A;  2W3L A;  5C3F A;  2XPX A;  2ROD A;  1MK3 A;  3DVU A;  1GJH A;  2VOG A;  3WIY A;  2VVX A;  2JBY A;  2O2F A;  3IHE A;  2ABO A;  2XA0 A;  1R2I A;  4U2V A;  1R2D A;  2M5B A;  4QVX A;  3JRV A;  4BD2 A;  2JBX A;  2VTY A;  1R2H A;  4HW4 A;  4M0S A;  4OQ5 A;  1YSW A;  2BZW A;  4BBB A;  2O22 A;  4G35 A;  4BPJ A;  4OYD A;  4D2M A;  3MK8 A;  2ME8 A;  1O0L A;  2VOI A;  1PQ0 A;  4UF2 A;  4LQK A;  1DDB A;  5JSB A;  4HW2 A;  4UF1 A;  4ZIH A;  2VOF A;  2VVW A;  2YV6 A;  4YJ4 A;  3QBR A;  1WSX A;  4BD8 A;  5IF4 A;  2K36 A;  3WIX A;  2LR1 A;  2PQK A;  4ZIF A;  4ZIG A;  3PK1 A;  4S0P A;  1F16 A;  1G5M A;  3D7V A;  1YSG A;  4D2L A;  3MQP A;  4WMR A;  4YK9 A;  4B4S A;  4QNQ A;  4K5B C;  1G5J A;  5FC4 A;  4S0O A;  2KBW A;  5KU9 A;  5FDO A;  1K3K A;  1PQ1 A;  2WH6 A;  1MAZ A;  4U2U A;  2B48 A;  4BBD A;  2JM6 B;  1AF3 A;  2V6Q A;  3KJ2 A;  2KUA A;  4MI8 A; 
#chains in the Genus database with same CATH homology
 1TY4 A;  4ZIE A;  1OHU A;  1R2G A;  2O2N A;  5KTG A;  3IHC A;  3KZ0 A;  1LXL A;  3KJ0 A;  2BID A;  3IIH A;  2NLA A;  1Q59 A;  2VM6 A;  4HW3 A;  2ROC A;  2IMT A;  5FMI A;  3CVA X;  1BXL A;  3BL2 A;  3KJ1 A;  2O2M A;  5FDR A;  4BDU A;  5C6H A;  4BD7 A;  2VOH A;  2MEJ A;  2A5Y A;  2NL9 A;  3IO9 A;  1R2E A;  4OQ6 A;  2JCN A;  2IMS A;  3ILC A;  4ZEQ A;  4BD6 A;  1ZY3 A;  2O21 A;  2MHS A;  3I1H A;  4ZBI A;  4ZII A;  3IHD A;  1YSI A;  1YSN A;  3IIG A;  4BPI A;  4ZBF A;  2K7W A;  5IEZ A;  2W3L A;  5C3F A;  2XPX A;  2ROD A;  1MK3 A;  3DVU A;  1GJH A;  2VOG A;  3WIY A;  2O2F A;  3IHE A;  2ABO A;  2XA0 A;  1R2I A;  4U2V A;  1R2D A;  2M5B A;  4QVX A;  4BD2 A;  1R2H A;  4HW4 A;  4OQ5 A;  1YSW A;  2BZW A;  2O22 A;  4G35 A;  4BPJ A;  4OYD A;  3MK8 A;  2ME8 A;  1O0L A;  2VOI A;  1PQ0 A;  1DDB A;  5JSB A;  4HW2 A;  4ZIH A;  2VOF A;  2YV6 A;  4YJ4 A;  3QBR A;  1WSX A;  4BD8 A;  5IF4 A;  3WIX A;  2LR1 A;  2PQK A;  4ZIF A;  4ZIG A;  3PK1 A;  4S0P A;  1F16 A;  1G5M A;  3D7V A;  1YSG A;  3MQP A;  4WMR A;  4YK9 A;  4B4S A;  4QNQ A;  4K5B C;  1G5J A;  5FC4 A;  4S0O A;  2KBW A;  5KU9 A;  5FDO A;  1K3K A;  1PQ1 A;  2WH6 A;  1MAZ A;  4U2U A;  2B48 A;  2JM6 B;  1AF3 A;  2V6Q A;  3KJ2 A;  2KUA A;  4MI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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