4ZIGA

Crystal structure of core/latch dimer of bax in complex with bidbh3mini
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
157
structure length
152
Chain Sequence
GGGPTSSEQIMKTGALLLQGFIQDRAGAPELALDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptosis regulator BAX
total genus 58
structure length 152
sequence length 157
ec nomenclature
pdb deposition date 2015-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4zigA00
1YSNA 4S0PA 4ZIEA 5C3FA 3IHCA 1WSXA 1K3KA 1YSWA 3DVUA 2M5BA 5C6HA 4ZBIA 3IIGA 1TY4A 4BPJA 4K5BC 2NLAA 4YJ4A 5IF4A 1MAZA 2RODA 5FC4A 2YV6A 4ZEQA 1R2HA 1G5MA 4ZIIA 2MEJA 2VOFA 4QNQA 2KBWA 2IMTA 3KZ0A 3MK8A 2VOHA 4ZBFA 2O21A 3MQPA 1AF3A 2BIDA 2VM6A 4BPIA 2ME8A 4QVXA 4OQ5A 1R2GA 2XPXA 3WIXA 2O2NA 1BXLA 3PK1A 3KJ0A 2O2FA 5IEZA 1GJHA 3KJ1A 4BD7A 2K7WA 4HW2A 4B4SA 2W3LA 3IHDA 2JM6B 3IO9A 2ABOA 4HW3A 3ILCA 2A5YA 1G5JA 4OYDA 2B48A 4BD8A 2JCNA 1YSIA 1LXLA 5FDRA 4BD6A 5JSBA 2O22A 3IIHA 2KUAA 4YK9A 2LR1A 4HW4A 4S0OA 1R2IA 5FDOA 1DDBA 2VOGA 2NL9A 1PQ1A 4WMRA 3I1HA 4G35A 1OHUA 2IMSA 2MHSA 5FMIA 5KTGA 2VOIA 2XA0A 2BZWA 1O0LA 2O2MA 2PQKA 3BL2A 4BD2A 4ZIHA 3WIYA 1MK3A 4BDUA 1R2DA 4ZIGA 5KU9A 4OQ6A 2ROCA 3IHEA 1Q59A 1R2EA 2V6QA 2WH6A 3CVAX 3KJ2A 4U2VA 4ZIFA 4U2UA 1ZY3A 4MI8A 3QBRA 3D7VA 1YSGA 1PQ0A 1F16A
chains in the Genus database with same CATH superfamily
1YSNA 4S0PA 4ZIEA 5C3FA 3IHCA 1WSXA 1K3KA 1YSWA 3DVUA 2M5BA 5C6HA 4ZBIA 4BBBA 3IIGA 1TY4A 4BPJA 4K5BC 2NLAA 4YJ4A 5IF4A 1MAZA 2RODA 5FC4A 2YV6A 4ZEQA 1R2HA 1G5MA 4ZIIA 2MEJA 2VOFA 4QNQA 2KBWA 2IMTA 3KZ0A 3MK8A 2VOHA 4ZBFA 2O21A 3MQPA 2JBXA 1AF3A 2BIDA 2VM6A 4BPIA 4BBDA 2ME8A 2UXEA 4QVXA 4OQ5A 2K36A 1R2GA 2XPXA 3WIXA 2O2NA 1BXLA 3PK1A 2JBYA 3KJ0A 2O2FA 5IEZA 1GJHA 4UF2A 4LQKA 3KJ1A 2VVYA 4BD7A 2K7WA 4D2MA 4HW2A 2O42A 4UF1A 4B4SA 2W3LA 3IHDA 2JM6B 3IO9A 2ABOA 4HW3A 3ILCA 2A5YA 1G5JA 4OYDA 2B48A 4BD8A 2JCNA 1YSIA 1LXLA 5FDRA 4BD6A 5JSBA 2O22A 2I39A 3IIHA 3JRVA 2KUAA 4YK9A 2LR1A 4HW4A 4S0OA 4BBCA 1R2IA 2VTYA 5FDOA 1DDBA 2VOGA 2NL9A 1PQ1A 4WMRA 3I1HA 4G35A 1OHUA 2IMSA 4M0SA 2VVXA 2MHSA 5FMIA 5KTGA 2VOIA 2XA0A 2BZWA 1O0LA 2O2MA 2PQKA 3BL2A 4BD2A 4ZIHA 3WIYA 1MK3A 4D2LA 4BDUA 1R2DA 4ZIGA 5KU9A 4OQ6A 2ROCA 3IHEA 1Q59A 1R2EA 2V6QA 2WH6A 3CVAX 3KJ2A 4U2VA 4ZIFA 4U2UA 1ZY3A 4MI8A 3QBRA 4UF3A 3D7VA 1YSGA 1PQ0A 2VVWA 1F16A
chains in the Genus database with same CATH topology
1YSNA 4S0PA 4ZIEA 5C3FA 3IHCA 1WSXA 1K3KA 1YSWA 3DVUA 2M5BA 5C6HA 4ZBIA 3IIGA 1TY4A 4BPJA 4K5BC 2NLAA 4YJ4A 5IF4A 1MAZA 2RODA 5FC4A 2YV6A 4ZEQA 1R2HA 1G5MA 4ZIIA 2MEJA 2VOFA 4QNQA 2KBWA 2IMTA 3KZ0A 3MK8A 2VOHA 4ZBFA 2O21A 3MQPA 1AF3A 2BIDA 2VM6A 4BPIA 2ME8A 4QVXA 4OQ5A 1R2GA 2XPXA 3WIXA 2O2NA 1BXLA 3PK1A 3KJ0A 2O2FA 5IEZA 1GJHA 3KJ1A 4BD7A 2K7WA 4HW2A 4B4SA 2W3LA 3IHDA 2JM6B 3IO9A 2ABOA 4HW3A 3ILCA 2A5YA 1G5JA 4OYDA 2B48A 4BD8A 2JCNA 1YSIA 1LXLA 5FDRA 4BD6A 5JSBA 2O22A 3IIHA 2KUAA 4YK9A 2LR1A 4HW4A 4S0OA 1R2IA 5FDOA 1DDBA 2VOGA 2NL9A 1PQ1A 4WMRA 3I1HA 4G35A 1OHUA 2IMSA 2MHSA 5FMIA 5KTGA 2VOIA 2XA0A 2BZWA 1O0LA 2O2MA 2PQKA 3BL2A 4BD2A 4ZIHA 3WIYA 1MK3A 4BDUA 1R2DA 4ZIGA 5KU9A 4OQ6A 2ROCA 3IHEA 1Q59A 1R2EA 2V6QA 2WH6A 3CVAX 3KJ2A 4U2VA 4ZIFA 4U2UA 1ZY3A 4MI8A 3QBRA 3D7VA 1YSGA 1PQ0A 1F16A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YSN A;  4S0P A;  4ZIE A;  5C3F A;  3IHC A;  1WSX A;  1K3K A;  1YSW A;  3DVU A;  2M5B A;  5C6H A;  4ZBI A;  3IIG A;  1TY4 A;  4BPJ A;  4K5B C;  2NLA A;  4YJ4 A;  5IF4 A;  1MAZ A;  2ROD A;  5FC4 A;  2YV6 A;  4ZEQ A;  1R2H A;  1G5M A;  4ZII A;  2MEJ A;  2VOF A;  4QNQ A;  2KBW A;  2IMT A;  3KZ0 A;  3MK8 A;  2VOH A;  4ZBF A;  2O21 A;  3MQP A;  1AF3 A;  2BID A;  2VM6 A;  4BPI A;  2ME8 A;  4QVX A;  4OQ5 A;  1R2G A;  2XPX A;  3WIX A;  2O2N A;  1BXL A;  3PK1 A;  3KJ0 A;  2O2F A;  5IEZ A;  1GJH A;  3KJ1 A;  4BD7 A;  2K7W A;  4HW2 A;  4B4S A;  2W3L A;  3IHD A;  2JM6 B;  3IO9 A;  2ABO A;  4HW3 A;  3ILC A;  2A5Y A;  1G5J A;  4OYD A;  2B48 A;  4BD8 A;  2JCN A;  1YSI A;  1LXL A;  5FDR A;  4BD6 A;  5JSB A;  2O22 A;  3IIH A;  2KUA A;  4YK9 A;  2LR1 A;  4HW4 A;  4S0O A;  1R2I A;  5FDO A;  1DDB A;  2VOG A;  2NL9 A;  1PQ1 A;  4WMR A;  3I1H A;  4G35 A;  1OHU A;  2IMS A;  2MHS A;  5FMI A;  5KTG A;  2VOI A;  2XA0 A;  2BZW A;  1O0L A;  2O2M A;  2PQK A;  3BL2 A;  4BD2 A;  4ZIH A;  3WIY A;  1MK3 A;  4BDU A;  1R2D A;  4ZIG A;  5KU9 A;  4OQ6 A;  2ROC A;  3IHE A;  1Q59 A;  1R2E A;  2V6Q A;  2WH6 A;  3CVA X;  3KJ2 A;  4U2V A;  4ZIF A;  4U2U A;  1ZY3 A;  4MI8 A;  3QBR A;  3D7V A;  1YSG A;  1PQ0 A;  1F16 A; 
#chains in the Genus database with same CATH topology
 1YSN A;  4S0P A;  4ZIE A;  5C3F A;  3IHC A;  1WSX A;  1K3K A;  1YSW A;  3DVU A;  2M5B A;  5C6H A;  4ZBI A;  4BBB A;  3IIG A;  1TY4 A;  4BPJ A;  4K5B C;  2NLA A;  4YJ4 A;  5IF4 A;  1MAZ A;  2ROD A;  5FC4 A;  2YV6 A;  4ZEQ A;  1R2H A;  1G5M A;  4ZII A;  2MEJ A;  2VOF A;  4QNQ A;  2KBW A;  2IMT A;  3KZ0 A;  3MK8 A;  2VOH A;  4ZBF A;  2O21 A;  3MQP A;  2JBX A;  1AF3 A;  2BID A;  2VM6 A;  4BPI A;  4BBD A;  2ME8 A;  2UXE A;  4QVX A;  4OQ5 A;  2K36 A;  1R2G A;  2XPX A;  3WIX A;  2O2N A;  1BXL A;  3PK1 A;  2JBY A;  3KJ0 A;  2O2F A;  5IEZ A;  1GJH A;  4UF2 A;  4LQK A;  3KJ1 A;  2VVY A;  4BD7 A;  2K7W A;  4D2M A;  4HW2 A;  2O42 A;  4UF1 A;  4B4S A;  2W3L A;  3IHD A;  2JM6 B;  3IO9 A;  2ABO A;  4HW3 A;  3ILC A;  2A5Y A;  1G5J A;  4OYD A;  2B48 A;  4BD8 A;  2JCN A;  1YSI A;  1LXL A;  5FDR A;  4BD6 A;  5JSB A;  2O22 A;  2I39 A;  3IIH A;  3JRV A;  2KUA A;  4YK9 A;  2LR1 A;  4HW4 A;  4S0O A;  4BBC A;  1R2I A;  2VTY A;  5FDO A;  1DDB A;  2VOG A;  2NL9 A;  1PQ1 A;  4WMR A;  3I1H A;  4G35 A;  1OHU A;  2IMS A;  4M0S A;  2VVX A;  2MHS A;  5FMI A;  5KTG A;  2VOI A;  2XA0 A;  2BZW A;  1O0L A;  2O2M A;  2PQK A;  3BL2 A;  4BD2 A;  4ZIH A;  3WIY A;  1MK3 A;  4D2L A;  4BDU A;  1R2D A;  4ZIG A;  5KU9 A;  4OQ6 A;  2ROC A;  3IHE A;  1Q59 A;  1R2E A;  2V6Q A;  2WH6 A;  3CVA X;  3KJ2 A;  4U2V A;  4ZIF A;  4U2U A;  1ZY3 A;  4MI8 A;  3QBR A;  4UF3 A;  3D7V A;  1YSG A;  1PQ0 A;  2VVW A;  1F16 A; 
#chains in the Genus database with same CATH homology
 1YSN A;  4S0P A;  4ZIE A;  5C3F A;  3IHC A;  1WSX A;  1K3K A;  1YSW A;  3DVU A;  2M5B A;  5C6H A;  4ZBI A;  3IIG A;  1TY4 A;  4BPJ A;  4K5B C;  2NLA A;  4YJ4 A;  5IF4 A;  1MAZ A;  2ROD A;  5FC4 A;  2YV6 A;  4ZEQ A;  1R2H A;  1G5M A;  4ZII A;  2MEJ A;  2VOF A;  4QNQ A;  2KBW A;  2IMT A;  3KZ0 A;  3MK8 A;  2VOH A;  4ZBF A;  2O21 A;  3MQP A;  1AF3 A;  2BID A;  2VM6 A;  4BPI A;  2ME8 A;  4QVX A;  4OQ5 A;  1R2G A;  2XPX A;  3WIX A;  2O2N A;  1BXL A;  3PK1 A;  3KJ0 A;  2O2F A;  5IEZ A;  1GJH A;  3KJ1 A;  4BD7 A;  2K7W A;  4HW2 A;  4B4S A;  2W3L A;  3IHD A;  2JM6 B;  3IO9 A;  2ABO A;  4HW3 A;  3ILC A;  2A5Y A;  1G5J A;  4OYD A;  2B48 A;  4BD8 A;  2JCN A;  1YSI A;  1LXL A;  5FDR A;  4BD6 A;  5JSB A;  2O22 A;  3IIH A;  2KUA A;  4YK9 A;  2LR1 A;  4HW4 A;  4S0O A;  1R2I A;  5FDO A;  1DDB A;  2VOG A;  2NL9 A;  1PQ1 A;  4WMR A;  3I1H A;  4G35 A;  1OHU A;  2IMS A;  2MHS A;  5FMI A;  5KTG A;  2VOI A;  2XA0 A;  2BZW A;  1O0L A;  2O2M A;  2PQK A;  3BL2 A;  4BD2 A;  4ZIH A;  3WIY A;  1MK3 A;  4BDU A;  1R2D A;  4ZIG A;  5KU9 A;  4OQ6 A;  2ROC A;  3IHE A;  1Q59 A;  1R2E A;  2V6Q A;  2WH6 A;  3CVA X;  3KJ2 A;  4U2V A;  4ZIF A;  4U2U A;  1ZY3 A;  4MI8 A;  3QBR A;  3D7V A;  1YSG A;  1PQ0 A;  1F16 A; 
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