4ZIHA

Crystal structure of core/latch dimer of bax in complex with bimbh3mini
Total Genus 54
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
155
structure length
145
Chain Sequence
GGGPTSSEQIMKTGALLLQGFIQDRAGRDPVPQDASTKKLSESLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALSTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Apoptosis regulator BAX
total genus 54
structure length 145
sequence length 155
ec nomenclature
pdb deposition date 2015-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00452 Bcl-2 Apoptosis regulator proteins, Bcl-2 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.437.10 Mainly Alpha Orthogonal Bundle Apoptosis Regulator Bcl-x Blc2-like 4zihA00
4QVXA 4ZIIA 2O2NA 1R2GA 5JSBA 1O0LA 2W3LA 4OYDA 5FDRA 1ZY3A 3IIGA 5KU9A 2KUAA 4BD6A 4WMRA 4ZEQA 5KTGA 3IHEA 2XPXA 4S0OA 3IO9A 4HW3A 5FC4A 3CVAX 1OHUA 4HW4A 3WIXA 3PK1A 4ZIEA 1MK3A 2V6QA 4BD7A 4BPIA 1LXLA 4ZBIA 4OQ5A 5IEZA 3D7VA 3IHDA 3KZ0A 5FMIA 1BXLA 2VOHA 4HW2A 4B4SA 2A5YA 1YSGA 4U2UA 3MQPA 4BDUA 1DDBA 3WIYA 4OQ6A 2PQKA 4BD2A 4YK9A 1R2DA 4S0PA 2MHSA 1WSXA 3KJ0A 5C3FA 2VOFA 3IHCA 2ABOA 3KJ1A 1YSNA 1Q59A 3I1HA 4QNQA 2O2MA 2WH6A 2MEJA 1R2EA 2NLAA 2ME8A 1R2HA 4ZIGA 4MI8A 2B48A 1PQ1A 2K7WA 1F16A 1GJHA 1G5JA 2VM6A 3DVUA 2O2FA 2VOIA 1YSIA 5IF4A 2O21A 3QBRA 3KJ2A 5C6HA 1AF3A 2IMSA 2ROCA 2VOGA 5FDOA 2BIDA 2M5BA 4BPJA 1G5MA 3MK8A 1R2IA 4U2VA 4BD8A 1TY4A 3BL2A 2RODA 2JCNA 2KBWA 2XA0A 3ILCA 4G35A 1MAZA 1YSWA 2JM6B 4K5BC 4ZBFA 2O22A 2IMTA 4ZIHA 2NL9A 4ZIFA 1PQ0A 2BZWA 2LR1A 4YJ4A 1K3KA 3IIHA 2YV6A
chains in the Genus database with same CATH superfamily
4QVXA 4ZIIA 2O2NA 1R2GA 5JSBA 1O0LA 2W3LA 4OYDA 5FDRA 1ZY3A 3IIGA 5KU9A 2KUAA 4BD6A 4WMRA 4ZEQA 5KTGA 2VVWA 3IHEA 2XPXA 4S0OA 3IO9A 4HW3A 4UF2A 5FC4A 3CVAX 1OHUA 4HW4A 3WIXA 3PK1A 4ZIEA 4UF1A 1MK3A 2V6QA 4BD7A 2O42A 4BPIA 2VTYA 1LXLA 4ZBIA 4BBBA 4OQ5A 5IEZA 3D7VA 3IHDA 3KZ0A 5FMIA 1BXLA 2VOHA 4HW2A 4B4SA 2A5YA 1YSGA 4U2UA 3MQPA 4BDUA 1DDBA 3WIYA 4OQ6A 2PQKA 4BD2A 4YK9A 1R2DA 4S0PA 2MHSA 4UF3A 1WSXA 3KJ0A 5C3FA 2VOFA 3IHCA 2ABOA 3KJ1A 4BBDA 1YSNA 1Q59A 2VVYA 3I1HA 4QNQA 2O2MA 2WH6A 2MEJA 4BBCA 1R2EA 2NLAA 2ME8A 1R2HA 4ZIGA 4MI8A 2VVXA 2B48A 1PQ1A 2K7WA 1F16A 1GJHA 1G5JA 2VM6A 4M0SA 4LQKA 3DVUA 2O2FA 2VOIA 1YSIA 5IF4A 2O21A 3QBRA 2JBXA 3KJ2A 5C6HA 1AF3A 2IMSA 2ROCA 2VOGA 5FDOA 2K36A 2BIDA 2M5BA 4BPJA 1G5MA 3MK8A 1R2IA 3JRVA 4U2VA 1TY4A 4BD8A 3BL2A 2RODA 2JCNA 2UXEA 2KBWA 2XA0A 3ILCA 4G35A 1MAZA 1YSWA 4D2MA 2JM6B 4D2LA 4K5BC 4ZBFA 2O22A 2JBYA 2IMTA 4ZIHA 2NL9A 4ZIFA 1PQ0A 2BZWA 2I39A 2LR1A 4YJ4A 1K3KA 3IIHA 2YV6A
chains in the Genus database with same CATH topology
4QVXA 4ZIIA 2O2NA 1R2GA 5JSBA 1O0LA 2W3LA 4OYDA 5FDRA 1ZY3A 3IIGA 5KU9A 2KUAA 4BD6A 4WMRA 4ZEQA 5KTGA 3IHEA 2XPXA 4S0OA 3IO9A 4HW3A 5FC4A 3CVAX 1OHUA 4HW4A 3WIXA 3PK1A 4ZIEA 1MK3A 2V6QA 4BD7A 4BPIA 1LXLA 4ZBIA 4OQ5A 5IEZA 3D7VA 3IHDA 3KZ0A 5FMIA 1BXLA 2VOHA 4HW2A 4B4SA 2A5YA 1YSGA 4U2UA 3MQPA 4BDUA 1DDBA 3WIYA 4OQ6A 2PQKA 4BD2A 4YK9A 1R2DA 4S0PA 2MHSA 1WSXA 3KJ0A 5C3FA 2VOFA 3IHCA 2ABOA 3KJ1A 1YSNA 1Q59A 3I1HA 4QNQA 2O2MA 2WH6A 2MEJA 1R2EA 2NLAA 2ME8A 1R2HA 4ZIGA 4MI8A 2B48A 1PQ1A 2K7WA 1F16A 1GJHA 1G5JA 2VM6A 3DVUA 2O2FA 2VOIA 1YSIA 5IF4A 2O21A 3QBRA 3KJ2A 5C6HA 1AF3A 2IMSA 2ROCA 2VOGA 5FDOA 2BIDA 2M5BA 4BPJA 1G5MA 3MK8A 1R2IA 4U2VA 4BD8A 1TY4A 3BL2A 2RODA 2JCNA 2KBWA 2XA0A 3ILCA 4G35A 1MAZA 1YSWA 2JM6B 4K5BC 4ZBFA 2O22A 2IMTA 4ZIHA 2NL9A 4ZIFA 1PQ0A 2BZWA 2LR1A 4YJ4A 1K3KA 3IIHA 2YV6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QVX A;  4ZII A;  2O2N A;  1R2G A;  5JSB A;  1O0L A;  2W3L A;  4OYD A;  5FDR A;  1ZY3 A;  3IIG A;  5KU9 A;  2KUA A;  4BD6 A;  4WMR A;  4ZEQ A;  5KTG A;  3IHE A;  2XPX A;  4S0O A;  3IO9 A;  4HW3 A;  5FC4 A;  3CVA X;  1OHU A;  4HW4 A;  3WIX A;  3PK1 A;  4ZIE A;  1MK3 A;  2V6Q A;  4BD7 A;  4BPI A;  1LXL A;  4ZBI A;  4OQ5 A;  5IEZ A;  3D7V A;  3IHD A;  3KZ0 A;  5FMI A;  1BXL A;  2VOH A;  4HW2 A;  4B4S A;  2A5Y A;  1YSG A;  4U2U A;  3MQP A;  4BDU A;  1DDB A;  3WIY A;  4OQ6 A;  2PQK A;  4BD2 A;  4YK9 A;  1R2D A;  4S0P A;  2MHS A;  1WSX A;  3KJ0 A;  5C3F A;  2VOF A;  3IHC A;  2ABO A;  3KJ1 A;  1YSN A;  1Q59 A;  3I1H A;  4QNQ A;  2O2M A;  2WH6 A;  2MEJ A;  1R2E A;  2NLA A;  2ME8 A;  1R2H A;  4ZIG A;  4MI8 A;  2B48 A;  1PQ1 A;  2K7W A;  1F16 A;  1GJH A;  1G5J A;  2VM6 A;  3DVU A;  2O2F A;  2VOI A;  1YSI A;  5IF4 A;  2O21 A;  3QBR A;  3KJ2 A;  5C6H A;  1AF3 A;  2IMS A;  2ROC A;  2VOG A;  5FDO A;  2BID A;  2M5B A;  4BPJ A;  1G5M A;  3MK8 A;  1R2I A;  4U2V A;  4BD8 A;  1TY4 A;  3BL2 A;  2ROD A;  2JCN A;  2KBW A;  2XA0 A;  3ILC A;  4G35 A;  1MAZ A;  1YSW A;  2JM6 B;  4K5B C;  4ZBF A;  2O22 A;  2IMT A;  4ZIH A;  2NL9 A;  4ZIF A;  1PQ0 A;  2BZW A;  2LR1 A;  4YJ4 A;  1K3K A;  3IIH A;  2YV6 A; 
#chains in the Genus database with same CATH topology
 4QVX A;  4ZII A;  2O2N A;  1R2G A;  5JSB A;  1O0L A;  2W3L A;  4OYD A;  5FDR A;  1ZY3 A;  3IIG A;  5KU9 A;  2KUA A;  4BD6 A;  4WMR A;  4ZEQ A;  5KTG A;  2VVW A;  3IHE A;  2XPX A;  4S0O A;  3IO9 A;  4HW3 A;  4UF2 A;  5FC4 A;  3CVA X;  1OHU A;  4HW4 A;  3WIX A;  3PK1 A;  4ZIE A;  4UF1 A;  1MK3 A;  2V6Q A;  4BD7 A;  2O42 A;  4BPI A;  2VTY A;  1LXL A;  4ZBI A;  4BBB A;  4OQ5 A;  5IEZ A;  3D7V A;  3IHD A;  3KZ0 A;  5FMI A;  1BXL A;  2VOH A;  4HW2 A;  4B4S A;  2A5Y A;  1YSG A;  4U2U A;  3MQP A;  4BDU A;  1DDB A;  3WIY A;  4OQ6 A;  2PQK A;  4BD2 A;  4YK9 A;  1R2D A;  4S0P A;  2MHS A;  4UF3 A;  1WSX A;  3KJ0 A;  5C3F A;  2VOF A;  3IHC A;  2ABO A;  3KJ1 A;  4BBD A;  1YSN A;  1Q59 A;  2VVY A;  3I1H A;  4QNQ A;  2O2M A;  2WH6 A;  2MEJ A;  4BBC A;  1R2E A;  2NLA A;  2ME8 A;  1R2H A;  4ZIG A;  4MI8 A;  2VVX A;  2B48 A;  1PQ1 A;  2K7W A;  1F16 A;  1GJH A;  1G5J A;  2VM6 A;  4M0S A;  4LQK A;  3DVU A;  2O2F A;  2VOI A;  1YSI A;  5IF4 A;  2O21 A;  3QBR A;  2JBX A;  3KJ2 A;  5C6H A;  1AF3 A;  2IMS A;  2ROC A;  2VOG A;  5FDO A;  2K36 A;  2BID A;  2M5B A;  4BPJ A;  1G5M A;  3MK8 A;  1R2I A;  3JRV A;  4U2V A;  1TY4 A;  4BD8 A;  3BL2 A;  2ROD A;  2JCN A;  2UXE A;  2KBW A;  2XA0 A;  3ILC A;  4G35 A;  1MAZ A;  1YSW A;  4D2M A;  2JM6 B;  4D2L A;  4K5B C;  4ZBF A;  2O22 A;  2JBY A;  2IMT A;  4ZIH A;  2NL9 A;  4ZIF A;  1PQ0 A;  2BZW A;  2I39 A;  2LR1 A;  4YJ4 A;  1K3K A;  3IIH A;  2YV6 A; 
#chains in the Genus database with same CATH homology
 4QVX A;  4ZII A;  2O2N A;  1R2G A;  5JSB A;  1O0L A;  2W3L A;  4OYD A;  5FDR A;  1ZY3 A;  3IIG A;  5KU9 A;  2KUA A;  4BD6 A;  4WMR A;  4ZEQ A;  5KTG A;  3IHE A;  2XPX A;  4S0O A;  3IO9 A;  4HW3 A;  5FC4 A;  3CVA X;  1OHU A;  4HW4 A;  3WIX A;  3PK1 A;  4ZIE A;  1MK3 A;  2V6Q A;  4BD7 A;  4BPI A;  1LXL A;  4ZBI A;  4OQ5 A;  5IEZ A;  3D7V A;  3IHD A;  3KZ0 A;  5FMI A;  1BXL A;  2VOH A;  4HW2 A;  4B4S A;  2A5Y A;  1YSG A;  4U2U A;  3MQP A;  4BDU A;  1DDB A;  3WIY A;  4OQ6 A;  2PQK A;  4BD2 A;  4YK9 A;  1R2D A;  4S0P A;  2MHS A;  1WSX A;  3KJ0 A;  5C3F A;  2VOF A;  3IHC A;  2ABO A;  3KJ1 A;  1YSN A;  1Q59 A;  3I1H A;  4QNQ A;  2O2M A;  2WH6 A;  2MEJ A;  1R2E A;  2NLA A;  2ME8 A;  1R2H A;  4ZIG A;  4MI8 A;  2B48 A;  1PQ1 A;  2K7W A;  1F16 A;  1GJH A;  1G5J A;  2VM6 A;  3DVU A;  2O2F A;  2VOI A;  1YSI A;  5IF4 A;  2O21 A;  3QBR A;  3KJ2 A;  5C6H A;  1AF3 A;  2IMS A;  2ROC A;  2VOG A;  5FDO A;  2BID A;  2M5B A;  4BPJ A;  1G5M A;  3MK8 A;  1R2I A;  4U2V A;  4BD8 A;  1TY4 A;  3BL2 A;  2ROD A;  2JCN A;  2KBW A;  2XA0 A;  3ILC A;  4G35 A;  1MAZ A;  1YSW A;  2JM6 B;  4K5B C;  4ZBF A;  2O22 A;  2IMT A;  4ZIH A;  2NL9 A;  4ZIF A;  1PQ0 A;  2BZW A;  2LR1 A;  4YJ4 A;  1K3K A;  3IIH A;  2YV6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...