5CZNA

2009 h1n1 pa endonuclease mutant e119d
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
179
structure length
179
Chain Sequence
GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Influenza a virus
molecule keywords Polymerase acidic protein
total genus 68
structure length 179
sequence length 179
ec nomenclature ec 3.1.-.-:
pdb deposition date 2015-07-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.91.90 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 5cznA00
5D42A 3HW3A 5JHVA 5CGVA 3HW4A 5DEBA 5FDDA 4AVGA 4AVQA 5D2OA 4E5EA 5CCYA 5DBSA 5D8UA 4AVLA 4E5FA 4E5JA 4E5IA 4E5HA 3HW6A 4AWFA 4AWGA 4CGSA 4AWHA 5CL0A 3HW5A 4ZI0A 4CHCA 4E5LA 4NFZA 5CZNA 4E5GA 4AWKA 4ZQQA 5FDGA 5D9JA 3EBJA 4AWMA 5I13A 4ZHZA 5JHTA 4CGXA 4YYLA 5D4GA 5EGAA 5DESA
chains in the Genus database with same CATH superfamily
3DPGA 3DVOA 3MQYA 5CCYA 4E5EA 5D2OA 3V1ZA 4E5JA 1CFRA 1BHMA 4E5LA 4AWMA 2BAMA 4CGXA 3WVPA 2XI7A 5DESA 3WVHA 5D42A 3HW3A 5JHVA 1BAMA 1KNVA 3BAMA 5FDDA 4AVQA 5DBSA 2P0JA 3ODHA 2GB7A 3WVIA 1FZRA 2PFJA 5CL0A 3HW5A 3N78A 4ZI0A 3WVGA 1D2IA 5CZNA 3V21A 4E5GA 5FDGA 3EBJA 4AWKA 2P14A 1M0DA 5CGVA 1DFMA 3HW4A 4AVGA 3MQ6A 3BM3A 4AVLA 1M0IA 4OC8A 3HW6A 1SDOA 3A4KA 2XI5A 4AWHA 4NFZA 2FOKA 3WVKA 1VRRA 3DW9A 5D9JA 5I13A 1ES8A 4ZHZA 5JHTA 4YYLA 5D4GA 5EGAA 1FOKA 4E5HA 3CAEA 5DEBA 1DC1A 4E5FA 5D8UA 1ESGA 4E5IA 4AWFA 4CGSA 2E52A 2EWFA 4CHCA 4R28A 4ZQQA 4F0PA 4F0QA 3V20A 3N7BA 2FQZA 4AWGA
chains in the Genus database with same CATH topology
3DPGA 3DVOA 3MQYA 5CCYA 4E5EA 5D2OA 3V1ZA 4E5JA 1CFRA 1BHMA 4E5LA 4AWMA 2BAMA 4CGXA 3WVPA 2XI7A 5DESA 3WVHA 5D42A 3HW3A 5JHVA 1BAMA 1KNVA 3BAMA 5FDDA 4AVQA 5DBSA 2P0JA 3ODHA 2GB7A 3WVIA 1FZRA 2PFJA 5CL0A 3HW5A 3N78A 4ZI0A 3WVGA 1D2IA 5CZNA 3V21A 4E5GA 5FDGA 3EBJA 4AWKA 2P14A 1M0DA 5CGVA 1DFMA 3HW4A 4AVGA 3MQ6A 3BM3A 4AVLA 1M0IA 4OC8A 3HW6A 1SDOA 3A4KA 2XI5A 4AWHA 4NFZA 2FOKA 3WVKA 1VRRA 3DW9A 5D9JA 5I13A 1ES8A 4ZHZA 5JHTA 4YYLA 5D4GA 5EGAA 1FOKA 4E5HA 3CAEA 5DEBA 1DC1A 4E5FA 5D8UA 1ESGA 4E5IA 4AWFA 4CGSA 2E52A 2EWFA 4CHCA 4R28A 4ZQQA 4F0PA 4F0QA 3V20A 3N7BA 2FQZA 4AWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D42 A;  3HW3 A;  5JHV A;  5CGV A;  3HW4 A;  5DEB A;  5FDD A;  4AVG A;  4AVQ A;  5D2O A;  4E5E A;  5CCY A;  5DBS A;  5D8U A;  4AVL A;  4E5F A;  4E5J A;  4E5I A;  4E5H A;  3HW6 A;  4AWF A;  4AWG A;  4CGS A;  4AWH A;  5CL0 A;  3HW5 A;  4ZI0 A;  4CHC A;  4E5L A;  4NFZ A;  5CZN A;  4E5G A;  4AWK A;  4ZQQ A;  5FDG A;  5D9J A;  3EBJ A;  4AWM A;  5I13 A;  4ZHZ A;  5JHT A;  4CGX A;  4YYL A;  5D4G A;  5EGA A;  5DES A; 
#chains in the Genus database with same CATH topology
 3DPG A;  3DVO A;  3MQY A;  5CCY A;  4E5E A;  5D2O A;  3V1Z A;  4E5J A;  1CFR A;  1BHM A;  4E5L A;  4AWM A;  2BAM A;  4CGX A;  3WVP A;  2XI7 A;  5DES A;  3WVH A;  5D42 A;  3HW3 A;  5JHV A;  1BAM A;  1KNV A;  3BAM A;  5FDD A;  4AVQ A;  5DBS A;  2P0J A;  3ODH A;  2GB7 A;  3WVI A;  1FZR A;  2PFJ A;  5CL0 A;  3HW5 A;  3N78 A;  4ZI0 A;  3WVG A;  1D2I A;  5CZN A;  3V21 A;  4E5G A;  5FDG A;  3EBJ A;  4AWK A;  2P14 A;  1M0D A;  5CGV A;  1DFM A;  3HW4 A;  4AVG A;  3MQ6 A;  3BM3 A;  4AVL A;  1M0I A;  4OC8 A;  3HW6 A;  1SDO A;  3A4K A;  2XI5 A;  4AWH A;  4NFZ A;  2FOK A;  3WVK A;  1VRR A;  3DW9 A;  5D9J A;  5I13 A;  1ES8 A;  4ZHZ A;  5JHT A;  4YYL A;  5D4G A;  5EGA A;  1FOK A;  4E5H A;  3CAE A;  5DEB A;  1DC1 A;  4E5F A;  5D8U A;  1ESG A;  4E5I A;  4AWF A;  4CGS A;  2E52 A;  2EWF A;  4CHC A;  4R28 A;  4ZQQ A;  4F0P A;  4F0Q A;  3V20 A;  3N7B A;  2FQZ A;  4AWG A; 
#chains in the Genus database with same CATH homology
 3DPG A;  3DVO A;  3MQY A;  5CCY A;  4E5E A;  5D2O A;  3V1Z A;  4E5J A;  1CFR A;  1BHM A;  4E5L A;  4AWM A;  2BAM A;  4CGX A;  3WVP A;  2XI7 A;  5DES A;  3WVH A;  5D42 A;  3HW3 A;  5JHV A;  1BAM A;  1KNV A;  3BAM A;  5FDD A;  4AVQ A;  5DBS A;  2P0J A;  3ODH A;  2GB7 A;  3WVI A;  1FZR A;  2PFJ A;  5CL0 A;  3HW5 A;  3N78 A;  4ZI0 A;  3WVG A;  1D2I A;  5CZN A;  3V21 A;  4E5G A;  5FDG A;  3EBJ A;  4AWK A;  2P14 A;  1M0D A;  5CGV A;  1DFM A;  3HW4 A;  4AVG A;  3MQ6 A;  3BM3 A;  4AVL A;  1M0I A;  4OC8 A;  3HW6 A;  1SDO A;  3A4K A;  2XI5 A;  4AWH A;  4NFZ A;  2FOK A;  3WVK A;  1VRR A;  3DW9 A;  5D9J A;  5I13 A;  1ES8 A;  4ZHZ A;  5JHT A;  4YYL A;  5D4G A;  5EGA A;  1FOK A;  4E5H A;  3CAE A;  5DEB A;  1DC1 A;  4E5F A;  5D8U A;  1ESG A;  4E5I A;  4AWF A;  4CGS A;  2E52 A;  2EWF A;  4CHC A;  4R28 A;  4ZQQ A;  4F0P A;  4F0Q A;  3V20 A;  3N7B A;  2FQZ A;  4AWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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