5CZNA

2009 h1n1 pa endonuclease mutant e119d
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
179
structure length
179
Chain Sequence
GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
pubmed doi rcsb
molecule tags Hydrolase
source organism Influenza a virus
molecule keywords Polymerase acidic protein
total genus 68
structure length 179
sequence length 179
ec nomenclature ec 3.1.-.-:
pdb deposition date 2015-07-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.91.90 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 5cznA00
4AWHA 5FDDA 5FDGA 4AWFA 5CL0A 4AVLA 4E5FA 4CHCA 4YYLA 5D2OA 4CGSA 5D42A 4NFZA 4ZHZA 3HW3A 4E5IA 3HW6A 4ZI0A 4AWMA 4AVGA 5D4GA 4E5EA 5DESA 5DEBA 5D8UA 5I13A 4ZQQA 4E5HA 5DBSA 4CGXA 3EBJA 3HW4A 3HW5A 5CGVA 4AWGA 5CCYA 4E5GA 5D9JA 4AWKA 5CZNA 4AVQA 5JHTA 4E5JA 5EGAA 5JHVA 4E5LA
chains in the Genus database with same CATH superfamily
4AWHA 4AWFA 5CL0A 2PFJA 5D42A 3A4KA 4ZHZA 3V1ZA 4E5IA 3DVOA 1M0IA 3ODHA 3N78A 5D8UA 2P14A 3WVHA 1M0DA 4AWKA 2FOKA 1BAMA 5EGAA 4R28A 5FDGA 4E5LA 5FDDA 4AVLA 5D2OA 1ESGA 4CGSA 2XI5A 4NFZA 1DC1A 1VRRA 2BAMA 3BAMA 4ZI0A 4AWMA 1CFRA 5DESA 3V21A 3DW9A 5DBSA 2XI7A 4AWGA 2P0JA 5D9JA 5CZNA 1KNVA 4F0PA 4OC8A 1FZRA 3CAEA 3DPGA 4CHCA 2E52A 4YYLA 1D2IA 3MQYA 3WVKA 4E5EA 5D4GA 4F0QA 3BM3A 4E5HA 3HW5A 5CGVA 3V20A 1DFMA 5JHTA 4AVQA 3MQ6A 2EWFA 3WVGA 1FOKA 4E5FA 3N7BA 1BHMA 2FQZA 3HW3A 3HW6A 1ES8A 4AVGA 5DEBA 5I13A 4ZQQA 4CGXA 3EBJA 3HW4A 5CCYA 2GB7A 1SDOA 4E5GA 3WVIA 4E5JA 5JHVA 3WVPA
chains in the Genus database with same CATH topology
4AWHA 4AWFA 5CL0A 2PFJA 5D42A 3A4KA 4ZHZA 3V1ZA 4E5IA 3DVOA 1M0IA 3ODHA 3N78A 5D8UA 2P14A 3WVHA 1M0DA 4AWKA 2FOKA 1BAMA 5EGAA 4R28A 5FDGA 4E5LA 5FDDA 4AVLA 5D2OA 1ESGA 4CGSA 2XI5A 4NFZA 1DC1A 1VRRA 2BAMA 3BAMA 4ZI0A 4AWMA 1CFRA 5DESA 3V21A 3DW9A 5DBSA 2XI7A 4AWGA 2P0JA 5D9JA 5CZNA 1KNVA 4F0PA 4OC8A 1FZRA 3CAEA 3DPGA 4CHCA 2E52A 4YYLA 1D2IA 3MQYA 3WVKA 4E5EA 5D4GA 4F0QA 3BM3A 4E5HA 3HW5A 5CGVA 3V20A 1DFMA 5JHTA 4AVQA 3MQ6A 2EWFA 3WVGA 1FOKA 4E5FA 3N7BA 1BHMA 2FQZA 3HW3A 3HW6A 1ES8A 4AVGA 5DEBA 5I13A 4ZQQA 4CGXA 3EBJA 3HW4A 5CCYA 2GB7A 1SDOA 4E5GA 3WVIA 4E5JA 5JHVA 3WVPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4AWH A;  5FDD A;  5FDG A;  4AWF A;  5CL0 A;  4AVL A;  4E5F A;  4CHC A;  4YYL A;  5D2O A;  4CGS A;  5D42 A;  4NFZ A;  4ZHZ A;  3HW3 A;  4E5I A;  3HW6 A;  4ZI0 A;  4AWM A;  4AVG A;  5D4G A;  4E5E A;  5DES A;  5DEB A;  5D8U A;  5I13 A;  4ZQQ A;  4E5H A;  5DBS A;  4CGX A;  3EBJ A;  3HW4 A;  3HW5 A;  5CGV A;  4AWG A;  5CCY A;  4E5G A;  5D9J A;  4AWK A;  5CZN A;  4AVQ A;  5JHT A;  4E5J A;  5EGA A;  5JHV A;  4E5L A; 
#chains in the Genus database with same CATH topology
 4AWH A;  4AWF A;  5CL0 A;  2PFJ A;  5D42 A;  3A4K A;  4ZHZ A;  3V1Z A;  4E5I A;  3DVO A;  1M0I A;  3ODH A;  3N78 A;  5D8U A;  2P14 A;  3WVH A;  1M0D A;  4AWK A;  2FOK A;  1BAM A;  5EGA A;  4R28 A;  5FDG A;  4E5L A;  5FDD A;  4AVL A;  5D2O A;  1ESG A;  4CGS A;  2XI5 A;  4NFZ A;  1DC1 A;  1VRR A;  2BAM A;  3BAM A;  4ZI0 A;  4AWM A;  1CFR A;  5DES A;  3V21 A;  3DW9 A;  5DBS A;  2XI7 A;  4AWG A;  2P0J A;  5D9J A;  5CZN A;  1KNV A;  4F0P A;  4OC8 A;  1FZR A;  3CAE A;  3DPG A;  4CHC A;  2E52 A;  4YYL A;  1D2I A;  3MQY A;  3WVK A;  4E5E A;  5D4G A;  4F0Q A;  3BM3 A;  4E5H A;  3HW5 A;  5CGV A;  3V20 A;  1DFM A;  5JHT A;  4AVQ A;  3MQ6 A;  2EWF A;  3WVG A;  1FOK A;  4E5F A;  3N7B A;  1BHM A;  2FQZ A;  3HW3 A;  3HW6 A;  1ES8 A;  4AVG A;  5DEB A;  5I13 A;  4ZQQ A;  4CGX A;  3EBJ A;  3HW4 A;  5CCY A;  2GB7 A;  1SDO A;  4E5G A;  3WVI A;  4E5J A;  5JHV A;  3WVP A; 
#chains in the Genus database with same CATH homology
 4AWH A;  4AWF A;  5CL0 A;  2PFJ A;  5D42 A;  3A4K A;  4ZHZ A;  3V1Z A;  4E5I A;  3DVO A;  1M0I A;  3ODH A;  3N78 A;  5D8U A;  2P14 A;  3WVH A;  1M0D A;  4AWK A;  2FOK A;  1BAM A;  5EGA A;  4R28 A;  5FDG A;  4E5L A;  5FDD A;  4AVL A;  5D2O A;  1ESG A;  4CGS A;  2XI5 A;  4NFZ A;  1DC1 A;  1VRR A;  2BAM A;  3BAM A;  4ZI0 A;  4AWM A;  1CFR A;  5DES A;  3V21 A;  3DW9 A;  5DBS A;  2XI7 A;  4AWG A;  2P0J A;  5D9J A;  5CZN A;  1KNV A;  4F0P A;  4OC8 A;  1FZR A;  3CAE A;  3DPG A;  4CHC A;  2E52 A;  4YYL A;  1D2I A;  3MQY A;  3WVK A;  4E5E A;  5D4G A;  4F0Q A;  3BM3 A;  4E5H A;  3HW5 A;  5CGV A;  3V20 A;  1DFM A;  5JHT A;  4AVQ A;  3MQ6 A;  2EWF A;  3WVG A;  1FOK A;  4E5F A;  3N7B A;  1BHM A;  2FQZ A;  3HW3 A;  3HW6 A;  1ES8 A;  4AVG A;  5DEB A;  5I13 A;  4ZQQ A;  4CGX A;  3EBJ A;  3HW4 A;  5CCY A;  2GB7 A;  1SDO A;  4E5G A;  3WVI A;  4E5J A;  5JHV A;  3WVP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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