5DEBA

2009 h1n1 pa endonuclease mutant e119d in complex with rump
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
179
structure length
179
Chain Sequence
GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIDIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Influenza a virus
molecule keywords Polymerase acidic protein
total genus 66
structure length 179
sequence length 179
ec nomenclature ec 3.1.-.-:
pdb deposition date 2015-08-25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.91.90 Alpha Beta 3-Layer(aba) Sandwich Restriction Endonuclease Restriction Endonuclease 5debA00
3HW6A 4E5JA 5D42A 5DESA 5JHTA 4ZQQA 3HW3A 5CGVA 4E5LA 4AVLA 3EBJA 5EGAA 4ZHZA 5FDDA 4E5GA 5DBSA 4AWFA 4CGSA 5JHVA 4YYLA 5CCYA 4ZI0A 5DEBA 4AWHA 4AVGA 4E5IA 4E5FA 3HW4A 4AWMA 5I13A 4E5EA 4NFZA 3HW5A 4AWGA 5D2OA 5D8UA 5CZNA 5FDGA 4AVQA 4AWKA 5D9JA 4CHCA 4E5HA 5CL0A 5D4GA 4CGXA
chains in the Genus database with same CATH superfamily
3HW6A 4E5JA 3WVIA 5CGVA 1ESGA 1DC1A 4CGSA 4YYLA 5CCYA 3WVHA 2FOKA 4ZI0A 3MQYA 2P14A 4AWHA 2EWFA 1M0IA 2FQZA 4AVQA 1VRRA 4ZHZA 5CL0A 5D4GA 4CGXA 3DPGA 5JHTA 4ZQQA 3HW3A 3DVOA 4AVLA 3EBJA 4E5GA 5JHVA 1BAMA 1KNVA 3V1ZA 3N7BA 4E5IA 3ODHA 3HW4A 5D2OA 5CZNA 4AWKA 3A4KA 3DW9A 5D42A 4R28A 4E5LA 5EGAA 5DBSA 4AWFA 1FZRA 3WVKA 3N78A 4OC8A 5DEBA 3WVGA 2E52A 3BM3A 1DFMA 4AWMA 1BHMA 5I13A 1M0DA 3MQ6A 2GB7A 5D8UA 2BAMA 1SDOA 1D2IA 5DESA 4F0QA 5FDDA 3V21A 2P0JA 3BAMA 1FOKA 4F0PA 1CFRA 4AVGA 4E5FA 3CAEA 4E5EA 4NFZA 3HW5A 2XI5A 4AWGA 2PFJA 5FDGA 3WVPA 1ES8A 2XI7A 5D9JA 4CHCA 3V20A 4E5HA
chains in the Genus database with same CATH topology
3HW6A 4E5JA 3WVIA 5CGVA 1ESGA 1DC1A 4CGSA 4YYLA 5CCYA 3WVHA 2FOKA 4ZI0A 3MQYA 2P14A 4AWHA 2EWFA 1M0IA 2FQZA 4AVQA 1VRRA 4ZHZA 5CL0A 5D4GA 4CGXA 3DPGA 5JHTA 4ZQQA 3HW3A 3DVOA 4AVLA 3EBJA 4E5GA 5JHVA 1BAMA 1KNVA 3V1ZA 3N7BA 4E5IA 3ODHA 3HW4A 5D2OA 5CZNA 4AWKA 3A4KA 3DW9A 5D42A 4R28A 4E5LA 5EGAA 5DBSA 4AWFA 1FZRA 3WVKA 3N78A 4OC8A 5DEBA 3WVGA 2E52A 3BM3A 1DFMA 4AWMA 1BHMA 5I13A 1M0DA 3MQ6A 2GB7A 5D8UA 2BAMA 1SDOA 1D2IA 5DESA 4F0QA 5FDDA 3V21A 2P0JA 3BAMA 1FOKA 4F0PA 1CFRA 4AVGA 4E5FA 3CAEA 4E5EA 4NFZA 3HW5A 2XI5A 4AWGA 2PFJA 5FDGA 3WVPA 1ES8A 2XI7A 5D9JA 4CHCA 3V20A 4E5HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HW6 A;  4E5J A;  5D42 A;  5DES A;  5JHT A;  4ZQQ A;  3HW3 A;  5CGV A;  4E5L A;  4AVL A;  3EBJ A;  5EGA A;  4ZHZ A;  5FDD A;  4E5G A;  5DBS A;  4AWF A;  4CGS A;  5JHV A;  4YYL A;  5CCY A;  4ZI0 A;  5DEB A;  4AWH A;  4AVG A;  4E5I A;  4E5F A;  3HW4 A;  4AWM A;  5I13 A;  4E5E A;  4NFZ A;  3HW5 A;  4AWG A;  5D2O A;  5D8U A;  5CZN A;  5FDG A;  4AVQ A;  4AWK A;  5D9J A;  4CHC A;  4E5H A;  5CL0 A;  5D4G A;  4CGX A; 
#chains in the Genus database with same CATH topology
 3HW6 A;  4E5J A;  3WVI A;  5CGV A;  1ESG A;  1DC1 A;  4CGS A;  4YYL A;  5CCY A;  3WVH A;  2FOK A;  4ZI0 A;  3MQY A;  2P14 A;  4AWH A;  2EWF A;  1M0I A;  2FQZ A;  4AVQ A;  1VRR A;  4ZHZ A;  5CL0 A;  5D4G A;  4CGX A;  3DPG A;  5JHT A;  4ZQQ A;  3HW3 A;  3DVO A;  4AVL A;  3EBJ A;  4E5G A;  5JHV A;  1BAM A;  1KNV A;  3V1Z A;  3N7B A;  4E5I A;  3ODH A;  3HW4 A;  5D2O A;  5CZN A;  4AWK A;  3A4K A;  3DW9 A;  5D42 A;  4R28 A;  4E5L A;  5EGA A;  5DBS A;  4AWF A;  1FZR A;  3WVK A;  3N78 A;  4OC8 A;  5DEB A;  3WVG A;  2E52 A;  3BM3 A;  1DFM A;  4AWM A;  1BHM A;  5I13 A;  1M0D A;  3MQ6 A;  2GB7 A;  5D8U A;  2BAM A;  1SDO A;  1D2I A;  5DES A;  4F0Q A;  5FDD A;  3V21 A;  2P0J A;  3BAM A;  1FOK A;  4F0P A;  1CFR A;  4AVG A;  4E5F A;  3CAE A;  4E5E A;  4NFZ A;  3HW5 A;  2XI5 A;  4AWG A;  2PFJ A;  5FDG A;  3WVP A;  1ES8 A;  2XI7 A;  5D9J A;  4CHC A;  3V20 A;  4E5H A; 
#chains in the Genus database with same CATH homology
 3HW6 A;  4E5J A;  3WVI A;  5CGV A;  1ESG A;  1DC1 A;  4CGS A;  4YYL A;  5CCY A;  3WVH A;  2FOK A;  4ZI0 A;  3MQY A;  2P14 A;  4AWH A;  2EWF A;  1M0I A;  2FQZ A;  4AVQ A;  1VRR A;  4ZHZ A;  5CL0 A;  5D4G A;  4CGX A;  3DPG A;  5JHT A;  4ZQQ A;  3HW3 A;  3DVO A;  4AVL A;  3EBJ A;  4E5G A;  5JHV A;  1BAM A;  1KNV A;  3V1Z A;  3N7B A;  4E5I A;  3ODH A;  3HW4 A;  5D2O A;  5CZN A;  4AWK A;  3A4K A;  3DW9 A;  5D42 A;  4R28 A;  4E5L A;  5EGA A;  5DBS A;  4AWF A;  1FZR A;  3WVK A;  3N78 A;  4OC8 A;  5DEB A;  3WVG A;  2E52 A;  3BM3 A;  1DFM A;  4AWM A;  1BHM A;  5I13 A;  1M0D A;  3MQ6 A;  2GB7 A;  5D8U A;  2BAM A;  1SDO A;  1D2I A;  5DES A;  4F0Q A;  5FDD A;  3V21 A;  2P0J A;  3BAM A;  1FOK A;  4F0P A;  1CFR A;  4AVG A;  4E5F A;  3CAE A;  4E5E A;  4NFZ A;  3HW5 A;  2XI5 A;  4AWG A;  2PFJ A;  5FDG A;  3WVP A;  1ES8 A;  2XI7 A;  5D9J A;  4CHC A;  3V20 A;  4E5H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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