1N3EA

Crystal structure of i-crei bound to a palindromic dna sequence i (palindrome of left side of wildtype dna target sequence)
Total Genus 51
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
151
structure length
151
Chain Sequence
TKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3'
total genus 51
structure length 151
sequence length 151
chains with identical sequence B, G, H
ec nomenclature ec 3.1.-.-:
pdb deposition date 2002-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1n3eA00
1T9JA 3C0XA 3UVFA 1P8KZ 1DFAA 2VBLB 1UM2A 2CW7A 2XE0B 4AADA 1G9YA 2VBOA 2I3QA 4UT0A 2DCHX 1N3EA 3MISA 3QQYA 4AQUA 5AKNA 5A72A 3OORA 4YHXA 1N3FA 4D6OA 4AQXA 5A0MA 1MOWA 5AKMA 2VBJA 4UN8A 4UNBA 3HYJA 4Z1ZA 2EX5A 4AAFA 4UN9G 4UN7G 2VBNB 1U0DA 1B24A 4YITA 3MXAA 3OOLA 4UNCA 1LWTA 2VBOB 2VS8A 4AABA 5AKFA 4LOXA 3MXBA 5E63A 1JVAA 5A74A 4AAGA 2FLDA 1LWSA 4UN8G 3EH8A 1EF0A 5A0MB 5E67A 2VBJB 4D6NA 2AB5A 2O7MA 2QOJZ 3FD2A 5AK9A 1U0CA 5A77A 2VBLA 4EFJA 1VDEA 2XE0A 1M5XA 1BP7A 1T9IA 2VS7A 2CW8A 1R7MA 2I3PA 2VBNA 3R7PA 1AF5A 5E5OA 3MIPA 4UN9A 4UN7A 4YISA 4LQ0A 4AAEA 3MXBB 3HYIA 4UNAA 1DQ3A 5E5SA 3KO2A 5A78A 3C0WA 3E54A 1G9ZA 4Z20A 3MX9A 5A0WA 4Z1XA
chains in the Genus database with same CATH superfamily
1T9JA 3C0XA 2F4LA 3UVFA 1P8KZ 1DFAA 2VBLB 1UM2A 4KZSA 2CW7A 2XE0B 4AADA 1G9YA 2VBOA 2I3QA 4UT0A 2DCHX 1N3EA 3MISA 3QQYA 4AQUA 5AKNA 5A72A 3OORA 4YHXA 1N3FA 4D6OA 4AQXA 5A0MA 1MOWA 5AKMA 2VBJA 4UN8A 4UNBA 3HYJA 4Z1ZA 2EX5A 4AAFA 4UN9G 4UN7G 2VBNB 1U0DA 1B24A 4YITA 3MXAA 3OOLA 4UNCA 1LWTA 2VBOB 2VS8A 4AABA 5AKFA 4LOXA 3MXBA 5E63A 1JVAA 5A74A 4AAGA 2FLDA 1LWSA 4UN8G 3EH8A 1EF0A 5A0MB 5E67A 2VBJB 4D6NA 2AB5A 2O7MA 2QOJZ 3FD2A 5AK9A 1U0CA 5A77A 2VBLA 4EFJA 1VDEA 2XE0A 1M5XA 1BP7A 1T9IA 2VS7A 2CW8A 1R7MA 2I3PA 2VBNA 3R7PA 1AF5A 5E5OA 3MIPA 4UN9A 4UN7A 4YISA 4LQ0A 4AAEA 3MXBB 3HYIA 4UNAA 1DQ3A 5E5SA 3KO2A 5A78A 3C0WA 3E54A 1G9ZA 4Z20A 3MX9A 5A0WA 4Z1XA
chains in the Genus database with same CATH topology
1T9JA 3C0XA 3UVFA 1P8KZ 1DFAA 2VBLB 1UM2A 2CW7A 2XE0B 4AADA 1G9YA 2VBOA 2I3QA 4UT0A 2DCHX 1N3EA 3MISA 3QQYA 4AQUA 5AKNA 5A72A 3OORA 4YHXA 1N3FA 4D6OA 4AQXA 5A0MA 1MOWA 5AKMA 2VBJA 4UN8A 4UNBA 3HYJA 4Z1ZA 2EX5A 4AAFA 4UN9G 4UN7G 2VBNB 1U0DA 1B24A 4YITA 3MXAA 3OOLA 4UNCA 1LWTA 2VBOB 2VS8A 4AABA 5AKFA 4LOXA 3MXBA 5E63A 1JVAA 5A74A 4AAGA 2FLDA 1LWSA 4UN8G 3EH8A 1EF0A 5A0MB 5E67A 2VBJB 4D6NA 2AB5A 2O7MA 2QOJZ 3FD2A 5AK9A 1U0CA 5A77A 2VBLA 4EFJA 1VDEA 2XE0A 1M5XA 1BP7A 1T9IA 2VS7A 2CW8A 1R7MA 2I3PA 2VBNA 3R7PA 1AF5A 5E5OA 3MIPA 4UN9A 4UN7A 4YISA 4LQ0A 4AAEA 3MXBB 3HYIA 4UNAA 1DQ3A 5E5SA 3KO2A 5A78A 3C0WA 3E54A 1G9ZA 4Z20A 3MX9A 5A0WA 4Z1XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1T9J A;  3C0X A;  3UVF A;  1P8K Z;  1DFA A;  2VBL B;  1UM2 A;  2CW7 A;  2XE0 B;  4AAD A;  1G9Y A;  2VBO A;  2I3Q A;  4UT0 A;  2DCH X;  1N3E A;  3MIS A;  3QQY A;  4AQU A;  5AKN A;  5A72 A;  3OOR A;  4YHX A;  1N3F A;  4D6O A;  4AQX A;  5A0M A;  1MOW A;  5AKM A;  2VBJ A;  4UN8 A;  4UNB A;  3HYJ A;  4Z1Z A;  2EX5 A;  4AAF A;  4UN9 G;  4UN7 G;  2VBN B;  1U0D A;  1B24 A;  4YIT A;  3MXA A;  3OOL A;  4UNC A;  1LWT A;  2VBO B;  2VS8 A;  4AAB A;  5AKF A;  4LOX A;  3MXB A;  5E63 A;  1JVA A;  5A74 A;  4AAG A;  2FLD A;  1LWS A;  4UN8 G;  3EH8 A;  1EF0 A;  5A0M B;  5E67 A;  2VBJ B;  4D6N A;  2AB5 A;  2O7M A;  2QOJ Z;  3FD2 A;  5AK9 A;  1U0C A;  5A77 A;  2VBL A;  4EFJ A;  1VDE A;  2XE0 A;  1M5X A;  1BP7 A;  1T9I A;  2VS7 A;  2CW8 A;  1R7M A;  2I3P A;  2VBN A;  3R7P A;  1AF5 A;  5E5O A;  3MIP A;  4UN9 A;  4UN7 A;  4YIS A;  4LQ0 A;  4AAE A;  3MXB B;  3HYI A;  4UNA A;  1DQ3 A;  5E5S A;  3KO2 A;  5A78 A;  3C0W A;  3E54 A;  1G9Z A;  4Z20 A;  3MX9 A;  5A0W A;  4Z1X A; 
#chains in the Genus database with same CATH topology
 1T9J A;  3C0X A;  2F4L A;  3UVF A;  1P8K Z;  1DFA A;  2VBL B;  1UM2 A;  4KZS A;  2CW7 A;  2XE0 B;  4AAD A;  1G9Y A;  2VBO A;  2I3Q A;  4UT0 A;  2DCH X;  1N3E A;  3MIS A;  3QQY A;  4AQU A;  5AKN A;  5A72 A;  3OOR A;  4YHX A;  1N3F A;  4D6O A;  4AQX A;  5A0M A;  1MOW A;  5AKM A;  2VBJ A;  4UN8 A;  4UNB A;  3HYJ A;  4Z1Z A;  2EX5 A;  4AAF A;  4UN9 G;  4UN7 G;  2VBN B;  1U0D A;  1B24 A;  4YIT A;  3MXA A;  3OOL A;  4UNC A;  1LWT A;  2VBO B;  2VS8 A;  4AAB A;  5AKF A;  4LOX A;  3MXB A;  5E63 A;  1JVA A;  5A74 A;  4AAG A;  2FLD A;  1LWS A;  4UN8 G;  3EH8 A;  1EF0 A;  5A0M B;  5E67 A;  2VBJ B;  4D6N A;  2AB5 A;  2O7M A;  2QOJ Z;  3FD2 A;  5AK9 A;  1U0C A;  5A77 A;  2VBL A;  4EFJ A;  1VDE A;  2XE0 A;  1M5X A;  1BP7 A;  1T9I A;  2VS7 A;  2CW8 A;  1R7M A;  2I3P A;  2VBN A;  3R7P A;  1AF5 A;  5E5O A;  3MIP A;  4UN9 A;  4UN7 A;  4YIS A;  4LQ0 A;  4AAE A;  3MXB B;  3HYI A;  4UNA A;  1DQ3 A;  5E5S A;  3KO2 A;  5A78 A;  3C0W A;  3E54 A;  1G9Z A;  4Z20 A;  3MX9 A;  5A0W A;  4Z1X A; 
#chains in the Genus database with same CATH homology
 1T9J A;  3C0X A;  3UVF A;  1P8K Z;  1DFA A;  2VBL B;  1UM2 A;  2CW7 A;  2XE0 B;  4AAD A;  1G9Y A;  2VBO A;  2I3Q A;  4UT0 A;  2DCH X;  1N3E A;  3MIS A;  3QQY A;  4AQU A;  5AKN A;  5A72 A;  3OOR A;  4YHX A;  1N3F A;  4D6O A;  4AQX A;  5A0M A;  1MOW A;  5AKM A;  2VBJ A;  4UN8 A;  4UNB A;  3HYJ A;  4Z1Z A;  2EX5 A;  4AAF A;  4UN9 G;  4UN7 G;  2VBN B;  1U0D A;  1B24 A;  4YIT A;  3MXA A;  3OOL A;  4UNC A;  1LWT A;  2VBO B;  2VS8 A;  4AAB A;  5AKF A;  4LOX A;  3MXB A;  5E63 A;  1JVA A;  5A74 A;  4AAG A;  2FLD A;  1LWS A;  4UN8 G;  3EH8 A;  1EF0 A;  5A0M B;  5E67 A;  2VBJ B;  4D6N A;  2AB5 A;  2O7M A;  2QOJ Z;  3FD2 A;  5AK9 A;  1U0C A;  5A77 A;  2VBL A;  4EFJ A;  1VDE A;  2XE0 A;  1M5X A;  1BP7 A;  1T9I A;  2VS7 A;  2CW8 A;  1R7M A;  2I3P A;  2VBN A;  3R7P A;  1AF5 A;  5E5O A;  3MIP A;  4UN9 A;  4UN7 A;  4YIS A;  4LQ0 A;  4AAE A;  3MXB B;  3HYI A;  4UNA A;  1DQ3 A;  5E5S A;  3KO2 A;  5A78 A;  3C0W A;  3E54 A;  1G9Z A;  4Z20 A;  3MX9 A;  5A0W A;  4Z1X A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...