1R7MA

The homing endonuclease i-scei bound to its dna recognition region
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
223
structure length
223
Chain Sequence
NIKKNQVMNLGPNSKLLKEYKSQLIELNIEQFEAGIGLILGDAYIRSRDEGKTYCMQFEWKNKAYMDHVCLLYDQWVLSPPHKKERVNHLGNLVITWGAQTFKHQAFNKLANLFIVNNKKTIPNNLVENYLTPMSLAYWFMDDGGKWDYNKNSTNKSIVLNTQSFTFEEVEYLVKGLRNKFQLNCYVKINKNKPIIYIDSMSYLIFYNLIKPYLIPQMMYKLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
molecule keywords 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP*CP*AP*GP*GP*
total genus 72
structure length 223
sequence length 223
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2003-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03161 LAGLIDADG_2 LAGLIDADG DNA endonuclease family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1r7mA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 1r7mA02
4UNCA 5AKNA 3HYIA 2VBOB 3QQYA 1JVAA 3C0WA 2VBLB 5AKFA 5AK9A 2O7MA 4AAFA 1N3FA 4Z20A 4AADA 3MX9A 4YISA 2VS7A 4AAGA 1UM2A 5A0MB 4Z1ZA 2CW8A 2CW7A 1DFAA 2VBJA 4UN7G 4UT0A 4UNBA 1G9YA 3MXBB 4D6OA 1U0CA 4AQXA 4YHXA 1U0DA 1AF5A 4UNAA 3FD2A 3MISA 2VS8A 5A0WA 2QOJZ 1LWTA 3OORA 2XE0B 5E67A 5A78A 1P8KZ 4UN8A 3E54A 4EFJA 3C0XA 1EF0A 1M5XA 3MIPA 5A74A 4UN9A 2EX5A 4YITA 3R7PA 5E63A 1BP7A 5A77A 4AABA 3KO2A 2VBLA 3EH8A 4Z1XA 1B24A 4UN8G 2VBJB 4LQ0A 2AB5A 1T9IA 2I3PA 1LWSA 1DQ3A 3MXAA 1VDEA 1N3EA 5E5OA 5A0MA 4AQUA 4AAEA 2VBNA 5AKMA 2DCHX 3MXBA 1T9JA 5E5SA 1R7MA 2VBOA 4D6NA 3OOLA 1MOWA 5A72A 2FLDA 2VBNB 2I3QA 4LOXA 2XE0A 1G9ZA 3HYJA 4UN9G 3UVFA 4UN7A
chains in the Genus database with same CATH superfamily
4UNCA 5AKNA 3HYIA 2VBOB 3QQYA 1JVAA 3C0WA 2VBLB 5AKFA 5AK9A 2O7MA 4AAFA 1N3FA 4Z20A 4AADA 3MX9A 4YISA 2VS7A 4AAGA 1UM2A 5A0MB 4Z1ZA 2CW8A 2CW7A 1DFAA 2VBJA 4UN7G 4UT0A 4UNBA 1G9YA 3MXBB 4D6OA 1U0CA 4AQXA 4YHXA 1U0DA 1AF5A 4UNAA 3FD2A 3MISA 2VS8A 5A0WA 2QOJZ 1LWTA 3OORA 2XE0B 5E67A 5A78A 1P8KZ 4UN8A 3E54A 4EFJA 3C0XA 1EF0A 1M5XA 3MIPA 5A74A 4UN9A 2EX5A 4YITA 3R7PA 5E63A 1BP7A 5A77A 4AABA 3KO2A 2VBLA 3EH8A 4Z1XA 1B24A 4UN8G 2VBJB 4LQ0A 2AB5A 1T9IA 2I3PA 1LWSA 1DQ3A 3MXAA 1VDEA 2F4LA 1N3EA 5E5OA 4KZSA 5A0MA 4AQUA 4AAEA 2VBNA 5AKMA 2DCHX 3MXBA 1T9JA 5E5SA 1R7MA 2VBOA 4D6NA 3OOLA 1MOWA 5A72A 2FLDA 2VBNB 2I3QA 4LOXA 2XE0A 1G9ZA 3HYJA 4UN9G 3UVFA 4UN7A
chains in the Genus database with same CATH topology
4UNCA 5AKNA 3HYIA 2VBOB 3QQYA 1JVAA 3C0WA 2VBLB 5AKFA 5AK9A 2O7MA 4AAFA 1N3FA 4Z20A 4AADA 3MX9A 4YISA 2VS7A 4AAGA 1UM2A 5A0MB 4Z1ZA 2CW8A 2CW7A 1DFAA 2VBJA 4UN7G 4UT0A 4UNBA 1G9YA 3MXBB 4D6OA 1U0CA 4AQXA 4YHXA 1U0DA 1AF5A 4UNAA 3FD2A 3MISA 2VS8A 5A0WA 2QOJZ 1LWTA 3OORA 2XE0B 5E67A 5A78A 1P8KZ 4UN8A 3E54A 4EFJA 3C0XA 1EF0A 1M5XA 3MIPA 5A74A 4UN9A 2EX5A 4YITA 3R7PA 5E63A 1BP7A 5A77A 4AABA 3KO2A 2VBLA 3EH8A 4Z1XA 1B24A 4UN8G 2VBJB 4LQ0A 2AB5A 1T9IA 2I3PA 1LWSA 1DQ3A 3MXAA 1VDEA 1N3EA 5E5OA 5A0MA 4AQUA 4AAEA 2VBNA 5AKMA 2DCHX 3MXBA 1T9JA 5E5SA 1R7MA 2VBOA 4D6NA 3OOLA 1MOWA 5A72A 2FLDA 2VBNB 2I3QA 4LOXA 2XE0A 1G9ZA 3HYJA 4UN9G 3UVFA 4UN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UNC A;  5AKN A;  3HYI A;  2VBO B;  3QQY A;  1JVA A;  3C0W A;  2VBL B;  5AKF A;  5AK9 A;  2O7M A;  4AAF A;  1N3F A;  4Z20 A;  4AAD A;  3MX9 A;  4YIS A;  2VS7 A;  4AAG A;  1UM2 A;  5A0M B;  4Z1Z A;  2CW8 A;  2CW7 A;  1DFA A;  2VBJ A;  4UN7 G;  4UT0 A;  4UNB A;  1G9Y A;  3MXB B;  4D6O A;  1U0C A;  4AQX A;  4YHX A;  1U0D A;  1AF5 A;  4UNA A;  3FD2 A;  3MIS A;  2VS8 A;  5A0W A;  2QOJ Z;  1LWT A;  3OOR A;  2XE0 B;  5E67 A;  5A78 A;  1P8K Z;  4UN8 A;  3E54 A;  4EFJ A;  3C0X A;  1EF0 A;  1M5X A;  3MIP A;  5A74 A;  4UN9 A;  2EX5 A;  4YIT A;  3R7P A;  5E63 A;  1BP7 A;  5A77 A;  4AAB A;  3KO2 A;  2VBL A;  3EH8 A;  4Z1X A;  1B24 A;  4UN8 G;  2VBJ B;  4LQ0 A;  2AB5 A;  1T9I A;  2I3P A;  1LWS A;  1DQ3 A;  3MXA A;  1VDE A;  1N3E A;  5E5O A;  5A0M A;  4AQU A;  4AAE A;  2VBN A;  5AKM A;  2DCH X;  3MXB A;  1T9J A;  5E5S A;  1R7M A;  2VBO A;  4D6N A;  3OOL A;  1MOW A;  5A72 A;  2FLD A;  2VBN B;  2I3Q A;  4LOX A;  2XE0 A;  1G9Z A;  3HYJ A;  4UN9 G;  3UVF A;  4UN7 A; 
#chains in the Genus database with same CATH topology
 4UNC A;  5AKN A;  3HYI A;  2VBO B;  3QQY A;  1JVA A;  3C0W A;  2VBL B;  5AKF A;  5AK9 A;  2O7M A;  4AAF A;  1N3F A;  4Z20 A;  4AAD A;  3MX9 A;  4YIS A;  2VS7 A;  4AAG A;  1UM2 A;  5A0M B;  4Z1Z A;  2CW8 A;  2CW7 A;  1DFA A;  2VBJ A;  4UN7 G;  4UT0 A;  4UNB A;  1G9Y A;  3MXB B;  4D6O A;  1U0C A;  4AQX A;  4YHX A;  1U0D A;  1AF5 A;  4UNA A;  3FD2 A;  3MIS A;  2VS8 A;  5A0W A;  2QOJ Z;  1LWT A;  3OOR A;  2XE0 B;  5E67 A;  5A78 A;  1P8K Z;  4UN8 A;  3E54 A;  4EFJ A;  3C0X A;  1EF0 A;  1M5X A;  3MIP A;  5A74 A;  4UN9 A;  2EX5 A;  4YIT A;  3R7P A;  5E63 A;  1BP7 A;  5A77 A;  4AAB A;  3KO2 A;  2VBL A;  3EH8 A;  4Z1X A;  1B24 A;  4UN8 G;  2VBJ B;  4LQ0 A;  2AB5 A;  1T9I A;  2I3P A;  1LWS A;  1DQ3 A;  3MXA A;  1VDE A;  2F4L A;  1N3E A;  5E5O A;  4KZS A;  5A0M A;  4AQU A;  4AAE A;  2VBN A;  5AKM A;  2DCH X;  3MXB A;  1T9J A;  5E5S A;  1R7M A;  2VBO A;  4D6N A;  3OOL A;  1MOW A;  5A72 A;  2FLD A;  2VBN B;  2I3Q A;  4LOX A;  2XE0 A;  1G9Z A;  3HYJ A;  4UN9 G;  3UVF A;  4UN7 A; 
#chains in the Genus database with same CATH homology
 4UNC A;  5AKN A;  3HYI A;  2VBO B;  3QQY A;  1JVA A;  3C0W A;  2VBL B;  5AKF A;  5AK9 A;  2O7M A;  4AAF A;  1N3F A;  4Z20 A;  4AAD A;  3MX9 A;  4YIS A;  2VS7 A;  4AAG A;  1UM2 A;  5A0M B;  4Z1Z A;  2CW8 A;  2CW7 A;  1DFA A;  2VBJ A;  4UN7 G;  4UT0 A;  4UNB A;  1G9Y A;  3MXB B;  4D6O A;  1U0C A;  4AQX A;  4YHX A;  1U0D A;  1AF5 A;  4UNA A;  3FD2 A;  3MIS A;  2VS8 A;  5A0W A;  2QOJ Z;  1LWT A;  3OOR A;  2XE0 B;  5E67 A;  5A78 A;  1P8K Z;  4UN8 A;  3E54 A;  4EFJ A;  3C0X A;  1EF0 A;  1M5X A;  3MIP A;  5A74 A;  4UN9 A;  2EX5 A;  4YIT A;  3R7P A;  5E63 A;  1BP7 A;  5A77 A;  4AAB A;  3KO2 A;  2VBL A;  3EH8 A;  4Z1X A;  1B24 A;  4UN8 G;  2VBJ B;  4LQ0 A;  2AB5 A;  1T9I A;  2I3P A;  1LWS A;  1DQ3 A;  3MXA A;  1VDE A;  1N3E A;  5E5O A;  5A0M A;  4AQU A;  4AAE A;  2VBN A;  5AKM A;  2DCH X;  3MXB A;  1T9J A;  5E5S A;  1R7M A;  2VBO A;  4D6N A;  3OOL A;  1MOW A;  5A72 A;  2FLD A;  2VBN B;  2I3Q A;  4LOX A;  2XE0 A;  1G9Z A;  3HYJ A;  4UN9 G;  3UVF A;  4UN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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