1R7M | Genus

Total Genus 72

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	72
sequence length	223
structure length	223
Chain Sequence	NIKKNQVMNLGPNSKLLKEYKSQLIELNIEQFEAGIGLILGDAYIRSRDEGKTYCMQFEWKNKAYMDHVCLLYDQWVLSPPHKKERVNHLGNLVITWGAQTFKHQAFNKLANLFIVNNKKTIPNNLVENYLTPMSLAYWFMDDGGKWDYNKNSTNKSIVLNTQSFTFEEVEYLVKGLRNKFQLNCYVKINKNKPIIYIDSMSYLIFYNLIKPYLIPQMMYKLP

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase/dna
source organism	Saccharomyces cerevisiae
publication title	The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity pubmed doi rcsb
molecule keywords	5'-D(CPAPCPGPCPTPAPGPGPGPAPTPAPAPCPAPGPGP*
total genus	72
structure length	223
sequence length	223
chains with identical sequence	B
ec nomenclature	ec 3.1.-.-:
pdb deposition date	2003-10-21

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03161	LAGLIDADG_2	LAGLIDADG DNA endonuclease family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.28.10	Alpha Beta	Roll	Endonuclease I-creI	Homing endonucleases	1r7mA01
3.10.28.10	Alpha Beta	Roll	Endonuclease I-creI	Homing endonucleases	1r7mA02

2I3PA 1DFAA 5A0MA 2I3QA 1N3FA 2EX5A 2AB5A 2VBJB 4Z1ZA 2DCHX 5A0MB 2QOJZ 4YISA 3OOLA 4LQ0A 2VBLA 4Z1XA 1B24A 1T9JA 1R7MA 4UN7A 4AQXA 4UNAA 2XE0B 4AAGA 2CW8A 2VBJA 5A72A 4Z20A 5E5OA 1MOWA 1UM2A 4UN8G 3KO2A 2O7MA 2XE0A 1U0CA 4AAFA 4YHXA 3HYIA 5AKFA 3EH8A 1VDEA 5E5SA 4YITA 2FLDA 5E67A 1LWSA 3MX9A 2VS8A 3E54A 5A0WA 4AABA 2VBOB 3FD2A 3MXBB 1LWTA 2VS7A 4UNCA 5AKMA 2VBNB 1G9ZA 4UN7G 3R7PA 2CW7A 4D6OA 5AK9A 2VBOA 1EF0A 4AAEA 4AQUA 3OORA 5AKNA 3MXBA 3HYJA 3MXAA 3MISA 1BP7A 2VBNA 1M5XA 4D6NA 3QQYA 4UN9A 5E63A 3MIPA 1JVAA 4AADA 1G9YA 1T9IA 1AF5A 4UN8A 1U0DA 1N3EA 1DQ3A 5A78A 4UT0A 5A74A 4LOXA 4EFJA 5A77A 3C0WA 2VBLB 3C0XA 3UVFA 4UNBA 1P8KZ 4UN9G
chains in the Genus database with same CATH superfamily

2I3PA 1DFAA 2F4LA 5A0MA 2I3QA 1N3FA 2EX5A 2AB5A 2VBJB 4Z1ZA 2DCHX 5A0MB 2QOJZ 4YISA 3OOLA 4LQ0A 2VBLA 4Z1XA 1B24A 1T9JA 1R7MA 4UN7A 4AQXA 4UNAA 2XE0B 4AAGA 2CW8A 2VBJA 5A72A 4Z20A 5E5OA 1MOWA 1UM2A 4UN8G 3KO2A 2O7MA 2XE0A 1U0CA 4AAFA 4YHXA 3HYIA 5AKFA 3EH8A 1VDEA 5E5SA 4YITA 2FLDA 5E67A 1LWSA 3MX9A 2VS8A 3E54A 5A0WA 4AABA 2VBOB 3FD2A 3MXBB 1LWTA 2VS7A 4UNCA 5AKMA 2VBNB 1G9ZA 4UN7G 3R7PA 2CW7A 4D6OA 5AK9A 2VBOA 1EF0A 4KZSA 4AQUA 4AAEA 3OORA 5AKNA 3MXBA 3HYJA 3MXAA 3MISA 1BP7A 2VBNA 1M5XA 4D6NA 3QQYA 4UN9A 5E63A 3MIPA 1JVAA 4AADA 1G9YA 1T9IA 1AF5A 4UN8A 1U0DA 1N3EA 1DQ3A 5A78A 4UT0A 5A74A 4LOXA 4EFJA 5A77A 3C0WA 2VBLB 3C0XA 3UVFA 4UNBA 1P8KZ 4UN9G
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2I3P A;  1DFA A;  5A0M A;  2I3Q A;  1N3F A;  2EX5 A;  2AB5 A;  2VBJ B;  4Z1Z A;  2DCH X;  5A0M B;  2QOJ Z;  4YIS A;  3OOL A;  4LQ0 A;  2VBL A;  4Z1X A;  1B24 A;  1T9J A;  1R7M A;  4UN7 A;  4AQX A;  4UNA A;  2XE0 B;  4AAG A;  2CW8 A;  2VBJ A;  5A72 A;  4Z20 A;  5E5O A;  1MOW A;  1UM2 A;  4UN8 G;  3KO2 A;  2O7M A;  2XE0 A;  1U0C A;  4AAF A;  4YHX A;  3HYI A;  5AKF A;  3EH8 A;  1VDE A;  5E5S A;  4YIT A;  2FLD A;  5E67 A;  1LWS A;  3MX9 A;  2VS8 A;  3E54 A;  5A0W A;  4AAB A;  2VBO B;  3FD2 A;  3MXB B;  1LWT A;  2VS7 A;  4UNC A;  5AKM A;  2VBN B;  1G9Z A;  4UN7 G;  3R7P A;  2CW7 A;  4D6O A;  5AK9 A;  2VBO A;  1EF0 A;  4AAE A;  4AQU A;  3OOR A;  5AKN A;  3MXB A;  3HYJ A;  3MXA A;  3MIS A;  1BP7 A;  2VBN A;  1M5X A;  4D6N A;  3QQY A;  4UN9 A;  5E63 A;  3MIP A;  1JVA A;  4AAD A;  1G9Y A;  1T9I A;  1AF5 A;  4UN8 A;  1U0D A;  1N3E A;  1DQ3 A;  5A78 A;  4UT0 A;  5A74 A;  4LOX A;  4EFJ A;  5A77 A;  3C0W A;  2VBL B;  3C0X A;  3UVF A;  4UNB A;  1P8K Z;  4UN9 G; 
#chains in the Genus database with same CATH topology
 2I3P A;  1DFA A;  2F4L A;  5A0M A;  2I3Q A;  1N3F A;  2EX5 A;  2AB5 A;  2VBJ B;  4Z1Z A;  2DCH X;  5A0M B;  2QOJ Z;  4YIS A;  3OOL A;  4LQ0 A;  2VBL A;  4Z1X A;  1B24 A;  1T9J A;  1R7M A;  4UN7 A;  4AQX A;  4UNA A;  2XE0 B;  4AAG A;  2CW8 A;  2VBJ A;  5A72 A;  4Z20 A;  5E5O A;  1MOW A;  1UM2 A;  4UN8 G;  3KO2 A;  2O7M A;  2XE0 A;  1U0C A;  4AAF A;  4YHX A;  3HYI A;  5AKF A;  3EH8 A;  1VDE A;  5E5S A;  4YIT A;  2FLD A;  5E67 A;  1LWS A;  3MX9 A;  2VS8 A;  3E54 A;  5A0W A;  4AAB A;  2VBO B;  3FD2 A;  3MXB B;  1LWT A;  2VS7 A;  4UNC A;  5AKM A;  2VBN B;  1G9Z A;  4UN7 G;  3R7P A;  2CW7 A;  4D6O A;  5AK9 A;  2VBO A;  1EF0 A;  4KZS A;  4AQU A;  4AAE A;  3OOR A;  5AKN A;  3MXB A;  3HYJ A;  3MXA A;  3MIS A;  1BP7 A;  2VBN A;  1M5X A;  4D6N A;  3QQY A;  4UN9 A;  5E63 A;  3MIP A;  1JVA A;  4AAD A;  1G9Y A;  1T9I A;  1AF5 A;  4UN8 A;  1U0D A;  1N3E A;  1DQ3 A;  5A78 A;  4UT0 A;  5A74 A;  4LOX A;  4EFJ A;  5A77 A;  3C0W A;  2VBL B;  3C0X A;  3UVF A;  4UNB A;  1P8K Z;  4UN9 G; 
#chains in the Genus database with same CATH homology
 2I3P A;  1DFA A;  5A0M A;  2I3Q A;  1N3F A;  2EX5 A;  2AB5 A;  2VBJ B;  4Z1Z A;  2DCH X;  5A0M B;  2QOJ Z;  4YIS A;  3OOL A;  4LQ0 A;  2VBL A;  4Z1X A;  1B24 A;  1T9J A;  1R7M A;  4UN7 A;  4AQX A;  4UNA A;  2XE0 B;  4AAG A;  2CW8 A;  2VBJ A;  5A72 A;  4Z20 A;  5E5O A;  1MOW A;  1UM2 A;  4UN8 G;  3KO2 A;  2O7M A;  2XE0 A;  1U0C A;  4AAF A;  4YHX A;  3HYI A;  5AKF A;  3EH8 A;  1VDE A;  5E5S A;  4YIT A;  2FLD A;  5E67 A;  1LWS A;  3MX9 A;  2VS8 A;  3E54 A;  5A0W A;  4AAB A;  2VBO B;  3FD2 A;  3MXB B;  1LWT A;  2VS7 A;  4UNC A;  5AKM A;  2VBN B;  1G9Z A;  4UN7 G;  3R7P A;  2CW7 A;  4D6O A;  5AK9 A;  2VBO A;  1EF0 A;  4AAE A;  4AQU A;  3OOR A;  5AKN A;  3MXB A;  3HYJ A;  3MXA A;  3MIS A;  1BP7 A;  2VBN A;  1M5X A;  4D6N A;  3QQY A;  4UN9 A;  5E63 A;  3MIP A;  1JVA A;  4AAD A;  1G9Y A;  1T9I A;  1AF5 A;  4UN8 A;  1U0D A;  1N3E A;  1DQ3 A;  5A78 A;  4UT0 A;  5A74 A;  4LOX A;  4EFJ A;  5A77 A;  3C0W A;  2VBL B;  3C0X A;  3UVF A;  4UNB A;  1P8K Z;  4UN9 G;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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1R7MA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations