1XKV | Genus

Total Genus 178

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	178
sequence length	528
structure length	515
Chain Sequence	QRLEALGIHPKKRVFWNTVSPVLVEHTLLRGEGLLAHHGPLVVDTTPYTGRSPKDKFVVREPEVEGEIWWGEVNQPFAPEAFEALYQRVVQYLSERDLYVQDLYAGADRRYRLAVRVVTESPWHALFARNMFILPRRFGAFVPGFTVVHAPYFQAVPERDGTRSEVFVGISFQRRLVLIVGTKYAGEIKKSIFTVMNYLMPKRGVFPMHASANVGKEGDVAVFFGLSGTGKTTLSTDPERPLIGDDEHGWSEDGVFNFEGGCYAKVIRLSPEHEPLIYKASNQFEAILENVVVNPESRRVQWDDDSKTENTRSSYPIAHLENVVESGVAGHPRAIFFLSADAYGVLPPIARLSPEEAMYYFLSGYTARVTEPRATFSACFGAPFLPMHPGVYARMLGEKIRKHAPRVYLVNTGWTGGPYGVGYRFPLPVTRALLKAALSGALENVPYRRDPVFGFEVPLEAPGVPQELLNPRETWADKEAYDQQARKLARLFQENFQKYASGVAKEVAEAGPRTE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Lyase
source organism	Thermus thermophilus
publication title	Structure of ATP-dependent phosphoenolpyruvate carboxykinase from Thermus thermophilus HB8 showing the structural basis of induced fit and thermostability. pubmed doi rcsb
molecule keywords	ATP-dependent phosphoenolpyruvate carboxykinase
total genus	178
structure length	515
sequence length	528
chains with identical sequence	B
ec nomenclature	ec 4.1.1.49: Phosphoenolpyruvate carboxykinase (ATP).
pdb deposition date	2004-09-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01293	PEPCK_ATP	Phosphoenolpyruvate carboxykinase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.170.8.10	Mainly Beta	Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 2	Phosphoenolpyruvate Carboxykinase, domain 2	1xkvA02
3.40.449.10	Alpha Beta	3-Layer(aba) Sandwich	Phosphoenolpyruvate Carboxykinase; domain 1	Phosphoenolpyruvate Carboxykinase, domain 1	1xkvA01
3.90.228.20	Alpha Beta	Alpha-Beta Complex	Phosphoenolpyruvate Carboxykinase; domain 3	Phosphoenolpyruvate Carboxykinase; domain 3	1xkvA03

5FH3A 4WL8A 4OX2A 1AYLA 1XKVA 2OLRA 2QEYA 5FH4A 2GMVA 1NHXA 3DT4A 2RKDA 1KHEA 1KHFA 4GMUA 4YWBA 4GNMA 4WOUA 2QF2A 4WIUA 4GMWA 3DT2A 1J3BA 1M51A 4WIEA 1YTMA 2FAHA 2QEWA 4WPVA 5FH1A 3MOHA 2QF1A 1OS1A 2PC9A 4GNQA 2RKEA 5FH5A 3MOFA 4YW8A 5I67A 2PXZX 4GNLA 4WPUA 5FH2A 4RCGA 3DT7A 3DTBA 1K3CA 1YLHA 5FH0A 4YWDA 1YVYA 2FAFA 2PY7X 1K3DA 2ZCIA 1KHGA 1KHBA 2RKAA 2RK7A 1YGGA 1II2A 2RK8A 3MOEA 4GNPA 4GNOA 4R43A 1AQ2A 2QZYA 4WPTA 4YW9A 4GMMA 4GMZA 2OLQA 1OENA
chains in the Genus database with same CATH superfamily

4KZQA 4L6SA 4TORA 4UVOA 4BU7A 4L0IA 5AEHA 4R6EA 4KRSA 4GV2A 4UFUA 5EBTA 4PNNA 4J22A 1KHFA 4YWBA 1UK1A 4HMHA 5LXPA 5ADRA 4WIUA 4M7BA 3MHKA 3DT2A 3MHJA 4GV4A 4X52A 4XHUA 4BUTA 4ZZYA 5AL3A 3L3LA 2QF1A 4MT9A 2PQFA 5FPGA 5ADQA 4OQAC 2PC9A 1GS0A 5A00A 4UVUA 4LI6A 1UK0A 4RCGA 4U6AA 3DTBA 4IUEA 3SMIA 4YWDA 4MSGA 4L7OA 4UI3A 5AKWA 4HLKA 4PNMA 5AL4A 1K3DA 5AL1A 3PAXA 4L2GA 4HKNA 4L0TA 1YGGA 1II2A 4GNPA 1WOKA 4KZUA 4UVPA 4BUYA 4R43A 4OPXC 4GMWA 4GMZA 3CE0A 2OLQA 4HHYA 4BUSA 4I9IA 1AYLA 1XKVA 4PJTA 4UVLA 4BU9A 4UUHA 4UX4A 5C5PA 4L0SA 5ADSA 3KR8A 3U9YA 4R5WA 4UW1A 4GNMA 1A26A 4BJBA 4W6EA 5ADTA 3GJWA 4WPVA 1YTMA 4HHZA 4AVWA 4J21A 5ECEA 4GNQA 5FH5A 2RD6A 4L0VA 4PAXA 4ZZXA 3MOFA 4L7RA 4BU5A 2X5YA 4J1ZA 5FH2A 3FHBA 4L32A 4UVSA 4L70A 4AVUA 1K3CA 4TVJA 3GEYA 4TJWA 5LYHA 4L7UA 4UI8A 2PY7X 4ZZZA 4TOSA 4PNTA 2RK7A 4HLMA 4TK5A 4BUIA 4F1QA 4L7PA 4LI7A 4YW9A 4WPTA 4L7NA 4GMMA 4PNQA 4UI5A 4OQBC 4HL5A 4PY4A 4LI8A 1EFYA 4BUVA 4UVWA 4L2FA 3P0PA 2GMVA 1NHXA 4L7LA 4J3LA 4RV6A 4TKFA 3UDDA 3DT4A 3P0NA 5AKUA 4L2KA 4UI7A 5AL5A 3UA9A 4BU3A 4BUUA 1KHEA 4GMUA 3KR7A 4BUFA 4PNSA 4N4VA 4W5SA 4J3MA 4UVZA 4BJ9A 5FH1A 2FAHA 4L33A 3MOHA 3SMJA 4PNRA 5C5RA 1OS1A 4N4TA 3BLJA 4GV0A 2RKEA 4BUDA 2RCWA 5AL2A 5I67A 4WPUA 2PAXA 4L0BA 4BFPA 4F0EA 4DVIA 2RF5A 1YVYA 4L6ZA 5LX6A 1KHGA 2RK8A 2RKAA 3KCZA 3GOYA 4PJVA 3MOEA 4KZLA 4BS4A 4BUEA 1AQ2A 3UH2A 2QZYA 3KJDA 4UFYA 4F1LA 4TJYA 4UNDA 4K4FA 4UI4A 1OENA 5FH3A 4W5IA 4WL8A 4OX2A 4K4EA 4TJUA 4N3RA 5C5QA 3W51A 2OLRA 2QEYA 5FH4A 4HKKA 4HLHA 3C4HA 4BJCA 4BUWA 4BUXA 4UHGA 4BU6A 2RKDA 4GV7A 4L10A 4UXBA 4WOUA 4PMLA 4UVTA 2QF2A 4OA7A 4UVNA 1J3BA 1M51A 4WIEA 2QEWA 4L09A 4MSKA 4BU8A 5FPFA 4L31A 4PNLA 4TKIA 3SE2A 4TK0A 5DCZA 4UVVA 3C49A 4HLGA 4HKIA 4UVYA 4L34A 4HLFA 4YW8A 2PXZX 4GNLA 3GN7A 4DQYC 3DT7A 3L3MA 1YLHA 5FH0A 4UI6A 5ETYA 4UVXA 2FAFA 2PAWA 3HKVA 3U9HA 2ZCIA 1KHBA 4BUAA 4HYFA 4GNOA 4TKGA 3P0QA 1PAXA 3UH4A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5FH3 A;  4WL8 A;  4OX2 A;  1AYL A;  1XKV A;  2OLR A;  2QEY A;  5FH4 A;  2GMV A;  1NHX A;  3DT4 A;  2RKD A;  1KHE A;  1KHF A;  4GMU A;  4YWB A;  4GNM A;  4WOU A;  2QF2 A;  4WIU A;  4GMW A;  3DT2 A;  1J3B A;  1M51 A;  4WIE A;  1YTM A;  2FAH A;  2QEW A;  4WPV A;  5FH1 A;  3MOH A;  2QF1 A;  1OS1 A;  2PC9 A;  4GNQ A;  2RKE A;  5FH5 A;  3MOF A;  4YW8 A;  5I67 A;  2PXZ X;  4GNL A;  4WPU A;  5FH2 A;  4RCG A;  3DT7 A;  3DTB A;  1K3C A;  1YLH A;  5FH0 A;  4YWD A;  1YVY A;  2FAF A;  2PY7 X;  1K3D A;  2ZCI A;  1KHG A;  1KHB A;  2RKA A;  2RK7 A;  1YGG A;  1II2 A;  2RK8 A;  3MOE A;  4GNP A;  4GNO A;  4R43 A;  1AQ2 A;  2QZY A;  4WPT A;  4YW9 A;  4GMM A;  4GMZ A;  2OLQ A;  1OEN A; 
#chains in the Genus database with same CATH topology
 4KZQ A;  4L6S A;  4TOR A;  4UVO A;  4BU7 A;  4L0I A;  5AEH A;  4R6E A;  4KRS A;  4GV2 A;  4UFU A;  5EBT A;  4PNN A;  4J22 A;  1KHF A;  4YWB A;  1UK1 A;  4HMH A;  5LXP A;  5ADR A;  4WIU A;  4M7B A;  3MHK A;  3DT2 A;  3MHJ A;  4GV4 A;  4X52 A;  4XHU A;  4BUT A;  4ZZY A;  5AL3 A;  3L3L A;  2QF1 A;  4MT9 A;  2PQF A;  5FPG A;  5ADQ A;  4OQA C;  2PC9 A;  1GS0 A;  5A00 A;  4UVU A;  4LI6 A;  1UK0 A;  4RCG A;  4U6A A;  3DTB A;  4IUE A;  3SMI A;  4YWD A;  4MSG A;  4L7O A;  4UI3 A;  5AKW A;  4HLK A;  4PNM A;  5AL4 A;  1K3D A;  5AL1 A;  3PAX A;  4L2G A;  4HKN A;  4L0T A;  1YGG A;  1II2 A;  4GNP A;  1WOK A;  4KZU A;  4UVP A;  4BUY A;  4R43 A;  4OPX C;  4GMW A;  4GMZ A;  3CE0 A;  2OLQ A;  4HHY A;  4BUS A;  4I9I A;  1AYL A;  1XKV A;  4PJT A;  4UVL A;  4BU9 A;  4UUH A;  4UX4 A;  5C5P A;  4L0S A;  5ADS A;  3KR8 A;  3U9Y A;  4R5W A;  4UW1 A;  4GNM A;  1A26 A;  4BJB A;  4W6E A;  5ADT A;  3GJW A;  4WPV A;  1YTM A;  4HHZ A;  4AVW A;  4J21 A;  5ECE A;  4GNQ A;  5FH5 A;  2RD6 A;  4L0V A;  4PAX A;  4ZZX A;  3MOF A;  4L7R A;  4BU5 A;  2X5Y A;  4J1Z A;  5FH2 A;  3FHB A;  4L32 A;  4UVS A;  4L70 A;  4AVU A;  1K3C A;  4TVJ A;  3GEY A;  4TJW A;  5LYH A;  4L7U A;  4UI8 A;  2PY7 X;  4ZZZ A;  4TOS A;  4PNT A;  2RK7 A;  4HLM A;  4TK5 A;  4BUI A;  4F1Q A;  4L7P A;  4LI7 A;  4YW9 A;  4WPT A;  4L7N A;  4GMM A;  4PNQ A;  4UI5 A;  4OQB C;  4HL5 A;  4PY4 A;  4LI8 A;  1EFY A;  4BUV A;  4UVW A;  4L2F A;  3P0P A;  2GMV A;  1NHX A;  4L7L A;  4J3L A;  4RV6 A;  4TKF A;  3UDD A;  3DT4 A;  3P0N A;  5AKU A;  4L2K A;  4UI7 A;  5AL5 A;  3UA9 A;  4BU3 A;  4BUU A;  1KHE A;  4GMU A;  3KR7 A;  4BUF A;  4PNS A;  4N4V A;  4W5S A;  4J3M A;  4UVZ A;  4BJ9 A;  5FH1 A;  2FAH A;  4L33 A;  3MOH A;  3SMJ A;  4PNR A;  5C5R A;  1OS1 A;  4N4T A;  3BLJ A;  4GV0 A;  2RKE A;  4BUD A;  2RCW A;  5AL2 A;  5I67 A;  4WPU A;  2PAX A;  4L0B A;  4BFP A;  4F0E A;  4DVI A;  2RF5 A;  1YVY A;  4L6Z A;  5LX6 A;  1KHG A;  2RK8 A;  2RKA A;  3KCZ A;  3GOY A;  4PJV A;  3MOE A;  4KZL A;  4BS4 A;  4BUE A;  1AQ2 A;  3UH2 A;  2QZY A;  3KJD A;  4UFY A;  4F1L A;  4TJY A;  4UND A;  4K4F A;  4UI4 A;  1OEN A;  5FH3 A;  4W5I A;  4WL8 A;  4OX2 A;  4K4E A;  4TJU A;  4N3R A;  5C5Q A;  3W51 A;  2OLR A;  2QEY A;  5FH4 A;  4HKK A;  4HLH A;  3C4H A;  4BJC A;  4BUW A;  4BUX A;  4UHG A;  4BU6 A;  2RKD A;  4GV7 A;  4L10 A;  4UXB A;  4WOU A;  4PML A;  4UVT A;  2QF2 A;  4OA7 A;  4UVN A;  1J3B A;  1M51 A;  4WIE A;  2QEW A;  4L09 A;  4MSK A;  4BU8 A;  5FPF A;  4L31 A;  4PNL A;  4TKI A;  3SE2 A;  4TK0 A;  5DCZ A;  4UVV A;  3C49 A;  4HLG A;  4HKI A;  4UVY A;  4L34 A;  4HLF A;  4YW8 A;  2PXZ X;  4GNL A;  3GN7 A;  4DQY C;  3DT7 A;  3L3M A;  1YLH A;  5FH0 A;  4UI6 A;  5ETY A;  4UVX A;  2FAF A;  2PAW A;  3HKV A;  3U9H A;  2ZCI A;  1KHB A;  4BUA A;  4HYF A;  4GNO A;  4TKG A;  3P0Q A;  1PAX A;  3UH4 A; 
#chains in the Genus database with same CATH homology
 4KZQ A;  4L6S A;  4TOR A;  4UVO A;  4BU7 A;  4L0I A;  5AEH A;  4R6E A;  4KRS A;  4GV2 A;  4UFU A;  5EBT A;  4PNN A;  4J22 A;  1KHF A;  4YWB A;  1UK1 A;  4HMH A;  5LXP A;  5ADR A;  4WIU A;  4M7B A;  3MHK A;  3DT2 A;  3MHJ A;  4GV4 A;  4X52 A;  4XHU A;  4BUT A;  4ZZY A;  5AL3 A;  3L3L A;  2QF1 A;  4MT9 A;  2PQF A;  5FPG A;  5ADQ A;  4OQA C;  2PC9 A;  1GS0 A;  5A00 A;  4UVU A;  4LI6 A;  1UK0 A;  4RCG A;  4U6A A;  3DTB A;  4IUE A;  3SMI A;  4YWD A;  4MSG A;  4L7O A;  4UI3 A;  5AKW A;  4HLK A;  4PNM A;  5AL4 A;  1K3D A;  5AL1 A;  3PAX A;  4L2G A;  4HKN A;  4L0T A;  1YGG A;  1II2 A;  4GNP A;  1WOK A;  4KZU A;  4UVP A;  4BUY A;  4R43 A;  4OPX C;  4GMW A;  4GMZ A;  3CE0 A;  2OLQ A;  4HHY A;  4BUS A;  4I9I A;  1AYL A;  1XKV A;  4PJT A;  4UVL A;  4BU9 A;  4UUH A;  4UX4 A;  5C5P A;  4L0S A;  5ADS A;  3KR8 A;  3U9Y A;  4R5W A;  4UW1 A;  4GNM A;  1A26 A;  4BJB A;  4W6E A;  5ADT A;  3GJW A;  4WPV A;  1YTM A;  4HHZ A;  4AVW A;  4J21 A;  5ECE A;  4GNQ A;  5FH5 A;  2RD6 A;  4L0V A;  4PAX A;  4ZZX A;  3MOF A;  4L7R A;  4BU5 A;  2X5Y A;  4J1Z A;  5FH2 A;  3FHB A;  4L32 A;  4UVS A;  4L70 A;  4AVU A;  1K3C A;  4TVJ A;  3GEY A;  4TJW A;  5LYH A;  4L7U A;  4UI8 A;  2PY7 X;  4ZZZ A;  4TOS A;  4PNT A;  2RK7 A;  4HLM A;  4TK5 A;  4BUI A;  4F1Q A;  4L7P A;  4LI7 A;  4YW9 A;  4WPT A;  4L7N A;  4GMM A;  4PNQ A;  4UI5 A;  4OQB C;  4HL5 A;  4PY4 A;  4LI8 A;  1EFY A;  4BUV A;  4UVW A;  4L2F A;  3P0P A;  2GMV A;  1NHX A;  4L7L A;  4J3L A;  4RV6 A;  4TKF A;  3UDD A;  3DT4 A;  3P0N A;  5AKU A;  4L2K A;  4UI7 A;  5AL5 A;  3UA9 A;  4BU3 A;  4BUU A;  1KHE A;  4GMU A;  3KR7 A;  4BUF A;  4PNS A;  4N4V A;  4W5S A;  4J3M A;  4UVZ A;  4BJ9 A;  5FH1 A;  2FAH A;  4L33 A;  3MOH A;  3SMJ A;  4PNR A;  5C5R A;  1OS1 A;  4N4T A;  3BLJ A;  4GV0 A;  2RKE A;  4BUD A;  2RCW A;  5AL2 A;  5I67 A;  4WPU A;  2PAX A;  4L0B A;  4BFP A;  4F0E A;  4DVI A;  2RF5 A;  1YVY A;  4L6Z A;  5LX6 A;  1KHG A;  2RK8 A;  2RKA A;  3KCZ A;  3GOY A;  4PJV A;  3MOE A;  4KZL A;  4BS4 A;  4BUE A;  1AQ2 A;  3UH2 A;  2QZY A;  3KJD A;  4UFY A;  4F1L A;  4TJY A;  4UND A;  4K4F A;  4UI4 A;  1OEN A;  5FH3 A;  4W5I A;  4WL8 A;  4OX2 A;  4K4E A;  4TJU A;  4N3R A;  5C5Q A;  3W51 A;  2OLR A;  2QEY A;  5FH4 A;  4HKK A;  4HLH A;  3C4H A;  4BJC A;  4BUW A;  4BUX A;  4UHG A;  4BU6 A;  2RKD A;  4GV7 A;  4L10 A;  4UXB A;  4WOU A;  4PML A;  4UVT A;  2QF2 A;  4OA7 A;  4UVN A;  1J3B A;  1M51 A;  4WIE A;  2QEW A;  4L09 A;  4MSK A;  4BU8 A;  5FPF A;  4L31 A;  4PNL A;  4TKI A;  3SE2 A;  4TK0 A;  5DCZ A;  4UVV A;  3C49 A;  4HLG A;  4HKI A;  4UVY A;  4L34 A;  4HLF A;  4YW8 A;  2PXZ X;  4GNL A;  3GN7 A;  4DQY C;  3DT7 A;  3L3M A;  1YLH A;  5FH0 A;  4UI6 A;  5ETY A;  4UVX A;  2FAF A;  2PAW A;  3HKV A;  3U9H A;  2ZCI A;  1KHB A;  4BUA A;  4HYF A;  4GNO A;  4TKG A;  3P0Q A;  1PAX A;  3UH4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1XKVA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations