4HHYA

Crystal structure of parp catalytic domain in complex with novel inhibitors
Total Genus 106
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
106
sequence length
349
structure length
349
Chain Sequence
KSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKAEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Design, Synthesis, and Biological Evaluation of a Series of Benzo[de][1,7]naphthyridin-7(8H)-ones Bearing a Functionalized Longer Chain Appendage as Novel PARP1 Inhibitors.
pubmed doi rcsb
molecule keywords Poly [ADP-ribose] polymerase 1
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
total genus 106
structure length 349
sequence length 349
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2012-10-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00644 PARP Poly(ADP-ribose) polymerase catalytic domain
A PF02877 PARP_reg Poly(ADP-ribose) polymerase, regulatory domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.142.10 Mainly Alpha Up-down Bundle Poly(ADP-ribose) Polymerase; domain 1 Poly(ADP-ribose) polymerase, regulatory domain 4hhyA01
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 4hhyA02
4ZZXA 4L7NA 4TK0A 1PAXA 4TKFA 4L2GA 4BUIA 5AL1A 4HL5A 4UI5A 4X52A 1GS0A 4I9IA 4L7OA 4PJVA 4L0SA 4UI7A 3KR7A 5A00A 5AL5A 5ETYA 4F1QA 4MSKA 4J21A 4BUYA 4TK5A 4TJUA 4TKIA 4GV2A 4BUXA 4UVUA 4R5WA 3UH2A 3UH4A 4F1LA 4UFUA 3P0PA 3U9HA 4UI3A 4KRSA 1EFYA 4BUEA 4TKGA 5LX6A 5ADRA 4K4EA 4HHZA 5ADQA 4PY4A 3C49A 3MHJA 4KZQA 1UK1A 4LI8A 4UVYA 4W5IA 4W5SA 3W51A 4UVZA 5AKWA 4BJ9A 4HLKA 4BUVA 4K4FA 4UX4A 4HMHA 4L7LA 4UVVA 4W6EA 3SMIA 4BS4A 4TJWA 4OQAC 4XHUA 2X5YA 4BUSA 4L70A 4TOSA 5AL3A 4HLFA 3BLJA 3GJWA 3L3MA 5ADTA 4UFYA 3C4HA 4BUDA 4L7PA 1A26A 3KJDA 4TVJA 4LI6A 4HLMA 4AVUA 4UHGA 4MSGA 4HLHA 4BU6A 2PAXA 4N4VA 4PMLA 4PNTA 4F0EA 5LYHA 4L09A 4L6SA 4L0TA 5C5QA 3GEYA 4UW1A 4BUUA 3UDDA 2PQFA 4GV0A 3HKVA 4PAXA 3U9YA 4DQYC 4BUAA 4L10A 4HKNA 4HKIA 4BU9A 3CE0A 5AL4A 4OA7A 4OQBC 4J3MA 4J1ZA 5C5RA 4HHYA 3GOYA 4L32A 4PNQA 2RCWA 2PAWA 3P0QA 4OPXC 4UVPA 4UVSA 3L3LA 4R6EA 4TORA 4UI8A 4L0VA 4UNDA 4BU8A 4L7UA 4L0IA 4RV6A 4BUTA 5ECEA 4DVIA 4UVLA 5ADSA 4TJYA 4UVTA 4PNSA 4N3RA 3UA9A 4ZZZA 5AEHA 4BUWA 4J22A 4BUFA 4AVWA 4MT9A 4UXBA 3KCZA 4BU5A 5AKUA 5FPFA 4L34A 4UI4A 5C5PA 5LXPA 4UVWA 4HYFA 4BU7A 4HKKA 3SMJA 4IUEA 4PNLA 5DCZA 4UVOA 5FPGA 1UK0A 4GV7A 3KR8A 3SE2A 3MHKA 4BJCA 3FHBA 2RF5A 4PNRA 4L0BA 4M7BA 4HLGA 4J3LA 4KZUA 3P0NA 3PAXA 5EBTA 4GV4A 4BFPA 4LI7A 4PNMA 3GN7A 4L6ZA 4PJTA 4UVNA 4ZZYA 4L7RA 4L2FA 4BJBA 5AL2A 4N4TA 4U6AA 2RD6A 4BU3A 4UVXA 4L31A 4UUHA 4L2KA 1WOKA 4KZLA 4L33A 4UI6A 4PNNA
chains in the Genus database with same CATH superfamily
2QEWA 4L7OA 5ETYA 4R5WA 4WIEA 5ADRA 4K4EA 5ADQA 4PY4A 1YGGA 4UVZA 4K4FA 1J3BA 4UX4A 3SMIA 3GJWA 4BUDA 1A26A 4HLMA 4HLHA 4N4VA 4L0TA 4UW1A 2QF1A 3UDDA 4L10A 4BU9A 1KHBA 5C5RA 3GOYA 2RKEA 4JNGA 4TORA 4BUTA 4RV6A 5ECEA 5ADSA 2FAFA 3UA9A 4GMZA 4BUFA 4MT9A 5AKUA 4L34A 5LXPA 2PXZX 4PNLA 5DCZA 4UVOA 1UK0A 3KR8A 1M51A 4HLGA 4J3LA 4KZUA 4LI7A 4PNMA 4PJTA 4BJBA 1YVYA 4N4TA 4BU3A 5FH3A 4L2KA 4PNNA 4ZZXA 4L7NA 4TK0A 4TKFA 4L2GA 4BUIA 5AL1A 1GS0A 4F1QA 3KR7A 5AL5A 4BGPA 4MSKA 3DT2A 4TJUA 4GV2A 4BUXA 3UH4A 2OLRA 4F1LA 3P0PA 4UI3A 4BUEA 2RKDA 4WOUA 4YW8A 4UVYA 4GMWA 4BJ9A 3DT4A 2X5YA 4L70A 5FH0A 3BLJA 1OENA 5ADTA 3KJDA 4BU6A 2PAXA 4PNTA 4F0EA 5LYHA 5C5QA 1YLHA 4BUUA 4PAXA 4HKNA 4IDXA 4OA7A 4J1ZA 4HHYA 4PNQA 3P0QA 1XKVA 4OPXC 4R43A 4R6EA 4L0VA 4UNDA 5FH1A 4UVLA 4UVTA 4J1GA 4N3RA 1KHGA 2PC9A 4UXBA 2FAHA 1KHFA 4UVWA 2RK7A 5FPGA 3SE2A 3MHKA 1K3CA 4BJCA 2OLQA 3PAXA 4YWBA 4GV4A 4BFPA 3GN7A 4L6ZA 4UVNA 4ZZYA 4L7RA 4L2FA 4UVXA 4L31A 4UUHA 4L0IA 4L33A 4UI6A 1AYLA 1PAXA 4X52A 4I9IA 4PJVA 4GNMA 5A00A 4TK5A 4TKIA 4UVUA 4GNOA 3MOHA 4UFUA 4KRSA 1EFYA 4TKGA 4HHZA 4YW9A 3C49A 3MHJA 4KZQA 4W5SA 4LI8A 4W5IA 3W51A 2GMVA 5AKWA 4HLKA 4BUVA 5FH4A 4HMHA 4L7LA 4UVVA 4W6EA 1AQ2A 4TJWA 4TOSA 4HLFA 4UFYA 3C4HA 4GNLA 4LI6A 4MSGA 2QZYA 4PMLA 4L6SA 3GEYA 4GV0A 2RKAA 4WIUA 3HKVA 4DQYC 4HKIA 4J3MA 2PAWA 4UVPA 3L3LA 1K3DA 4TJYA 1YTMA 1II2A 1OS1A 5C5PA 4HYFA 4BU7A 4HKKA 3SMJA 4IUEA 1NHXA 4IJSA 4PNRA 4L0BA 5EBTA 3P0NA 4OX2A 4RCGA 4WPTA 5AL2A 2RD6A 1WOKA 5FH5A 4KZLA 4HL5A 4UI5A 4L0SA 4UI7A 4J21A 4BUYA 2RK8A 3UH2A 3U9HA 4WL8A 5LX6A 4BHHB 1UK1A 4YWDA 4BS4A 4OQAC 4XHUA 4BUSA 2ZCIA 4WPVA 5AL3A 3DTBA 3L3MA 4L7PA 4TVJA 4GMUA 4AVUA 4UHGA 4L09A 4GNQA 2PQFA 3U9YA 4BUAA 3CE0A 5AL4A 4OQBC 4L32A 2RCWA 4GMMA 4UVSA 4IDUA 4UI8A 4BU8A 4L7UA 4DVIA 4IDUB 1KHEA 4PNSA 4WPUA 4ZZZA 5AEHA 4BUWA 4J22A 4AVWA 3KCZA 4BU5A 3MOEA 5FPFA 4UI4A 2PY7X 4GV7A 4J1JA 5I67A 3FHBA 2RF5A 4GNPA 3MOFA 2QF2A 4M7BA 3DT7A 3ZLAA 4U6AA 2QEYA 5FH2A 3ZL9A
chains in the Genus database with same CATH topology
4ZZXA 4L7NA 4TK0A 1PAXA 4TKFA 4L2GA 2QEWA 4BUIA 5AL1A 4HL5A 4UI5A 4X52A 1GS0A 4I9IA 4L7OA 4PJVA 4L0SA 4GNMA 3KR7A 5A00A 4UI7A 5AL5A 5ETYA 4MSKA 4J21A 4BUYA 4TK5A 3DT2A 4TJUA 4TKIA 4GV2A 4BUXA 4UVUA 2RK8A 4R5WA 4GNOA 3UH2A 3UH4A 2OLRA 3MOHA 4UFUA 4F1LA 3P0PA 3U9HA 4UI3A 4KRSA 1EFYA 4WIEA 4WL8A 4TKGA 4BUEA 5LX6A 2RKDA 5ADRA 4K4EA 4HHZA 4YW9A 5ADQA 4PY4A 4WOUA 3C49A 3MHJA 4KZQA 1UK1A 4LI8A 1YGGA 4UVYA 4W5IA 4GMWA 4W5SA 2GMVA 4YW8A 4YWDA 3W51A 4UVZA 5AKWA 4BJ9A 4HLKA 4BUVA 4K4FA 1J3BA 4UX4A 5FH4A 4HMHA 4L7LA 4UVVA 4W6EA 3SMIA 4BS4A 3DT4A 4OQAC 4TJWA 1AQ2A 4XHUA 2X5YA 4BUSA 4L70A 2ZCIA 4TOSA 5FH0A 4WPVA 5AL3A 4HLFA 3DTBA 3BLJA 3GJWA 3L3MA 1OENA 5ADTA 4UFYA 3C4HA 4BUDA 4L7PA 1A26A 3KJDA 4TVJA 4GNLA 4GMUA 4LI6A 4HLMA 4AVUA 4UHGA 4MSGA 4HLHA 2QZYA 2PAXA 4N4VA 4PMLA 4BU6A 4PNTA 4F0EA 5LYHA 4L09A 4L6SA 4GNQA 4L0TA 5C5QA 3GEYA 1YLHA 4UW1A 4BUUA 2QF1A 3UDDA 2PQFA 4GV0A 2RKAA 4WIUA 3HKVA 4PAXA 3U9YA 4DQYC 4BUAA 4L10A 4HKNA 4HKIA 4BU9A 3CE0A 4PNNA 5AL4A 4OA7A 4OQBC 4J3MA 1KHBA 4J1ZA 5C5RA 4HHYA 3GOYA 2RKEA 4L32A 4PNQA 2RCWA 2PAWA 3P0QA 1XKVA 4OPXC 4UVPA 4GMMA 4UVSA 3L3LA 4R43A 1K3DA 4R6EA 4TORA 4UI8A 4L0VA 4UNDA 4BU8A 4L7UA 4L0IA 4RV6A 5FH1A 4BUTA 5ECEA 4DVIA 4UVLA 5ADSA 4TJYA 1KHEA 4UVTA 2FAFA 1YTMA 4PNSA 4N3RA 4WPUA 4ZZZA 3UA9A 4F1QA 4GMZA 1II2A 1OS1A 5AEHA 4BUWA 4J22A 1KHGA 4BUFA 2PC9A 4AVWA 4MT9A 4UXBA 3KCZA 4BU5A 3MOEA 5AKUA 5FPFA 2FAHA 4L34A 1KHFA 4UI4A 5C5PA 4UVWA 4HYFA 4BU7A 2PXZX 4HKKA 3SMJA 5LXPA 4IUEA 2PY7X 2RK7A 1NHXA 4PNLA 5DCZA 4UVOA 5FPGA 1UK0A 4GV7A 3KR8A 3SE2A 3MHKA 1K3CA 3FHBA 2RF5A 4BJCA 5I67A 4GNPA 1M51A 4PNRA 3MOFA 2QF2A 4L0BA 4M7BA 4HLGA 4J3LA 2OLQA 3P0NA 3PAXA 4KZUA 5EBTA 4GV4A 4OX2A 4YWBA 4LI7A 4BFPA 4RCGA 4PNMA 3GN7A 4L6ZA 4PJTA 4UVNA 3DT7A 4ZZYA 4L7RA 4L2FA 4WPTA 1YVYA 5AL2A 4BJBA 4N4TA 4U6AA 2RD6A 4BU3A 2QEYA 4UVXA 4L31A 4UUHA 5FH2A 4L2KA 5FH3A 1WOKA 5FH5A 4KZLA 4L33A 4UI6A 1AYLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZZX A;  4L7N A;  4TK0 A;  1PAX A;  4TKF A;  4L2G A;  4BUI A;  5AL1 A;  4HL5 A;  4UI5 A;  4X52 A;  1GS0 A;  4I9I A;  4L7O A;  4PJV A;  4L0S A;  4UI7 A;  3KR7 A;  5A00 A;  5AL5 A;  5ETY A;  4F1Q A;  4MSK A;  4J21 A;  4BUY A;  4TK5 A;  4TJU A;  4TKI A;  4GV2 A;  4BUX A;  4UVU A;  4R5W A;  3UH2 A;  3UH4 A;  4F1L A;  4UFU A;  3P0P A;  3U9H A;  4UI3 A;  4KRS A;  1EFY A;  4BUE A;  4TKG A;  5LX6 A;  5ADR A;  4K4E A;  4HHZ A;  5ADQ A;  4PY4 A;  3C49 A;  3MHJ A;  4KZQ A;  1UK1 A;  4LI8 A;  4UVY A;  4W5I A;  4W5S A;  3W51 A;  4UVZ A;  5AKW A;  4BJ9 A;  4HLK A;  4BUV A;  4K4F A;  4UX4 A;  4HMH A;  4L7L A;  4UVV A;  4W6E A;  3SMI A;  4BS4 A;  4TJW A;  4OQA C;  4XHU A;  2X5Y A;  4BUS A;  4L70 A;  4TOS A;  5AL3 A;  4HLF A;  3BLJ A;  3GJW A;  3L3M A;  5ADT A;  4UFY A;  3C4H A;  4BUD A;  4L7P A;  1A26 A;  3KJD A;  4TVJ A;  4LI6 A;  4HLM A;  4AVU A;  4UHG A;  4MSG A;  4HLH A;  4BU6 A;  2PAX A;  4N4V A;  4PML A;  4PNT A;  4F0E A;  5LYH A;  4L09 A;  4L6S A;  4L0T A;  5C5Q A;  3GEY A;  4UW1 A;  4BUU A;  3UDD A;  2PQF A;  4GV0 A;  3HKV A;  4PAX A;  3U9Y A;  4DQY C;  4BUA A;  4L10 A;  4HKN A;  4HKI A;  4BU9 A;  3CE0 A;  5AL4 A;  4OA7 A;  4OQB C;  4J3M A;  4J1Z A;  5C5R A;  4HHY A;  3GOY A;  4L32 A;  4PNQ A;  2RCW A;  2PAW A;  3P0Q A;  4OPX C;  4UVP A;  4UVS A;  3L3L A;  4R6E A;  4TOR A;  4UI8 A;  4L0V A;  4UND A;  4BU8 A;  4L7U A;  4L0I A;  4RV6 A;  4BUT A;  5ECE A;  4DVI A;  4UVL A;  5ADS A;  4TJY A;  4UVT A;  4PNS A;  4N3R A;  3UA9 A;  4ZZZ A;  5AEH A;  4BUW A;  4J22 A;  4BUF A;  4AVW A;  4MT9 A;  4UXB A;  3KCZ A;  4BU5 A;  5AKU A;  5FPF A;  4L34 A;  4UI4 A;  5C5P A;  5LXP A;  4UVW A;  4HYF A;  4BU7 A;  4HKK A;  3SMJ A;  4IUE A;  4PNL A;  5DCZ A;  4UVO A;  5FPG A;  1UK0 A;  4GV7 A;  3KR8 A;  3SE2 A;  3MHK A;  4BJC A;  3FHB A;  2RF5 A;  4PNR A;  4L0B A;  4M7B A;  4HLG A;  4J3L A;  4KZU A;  3P0N A;  3PAX A;  5EBT A;  4GV4 A;  4BFP A;  4LI7 A;  4PNM A;  3GN7 A;  4L6Z A;  4PJT A;  4UVN A;  4ZZY A;  4L7R A;  4L2F A;  4BJB A;  5AL2 A;  4N4T A;  4U6A A;  2RD6 A;  4BU3 A;  4UVX A;  4L31 A;  4UUH A;  4L2K A;  1WOK A;  4KZL A;  4L33 A;  4UI6 A;  4PNN A; 
#chains in the Genus database with same CATH topology
 2QEW A;  4L7O A;  5ETY A;  4R5W A;  4WIE A;  5ADR A;  4K4E A;  5ADQ A;  4PY4 A;  1YGG A;  4UVZ A;  4K4F A;  1J3B A;  4UX4 A;  3SMI A;  3GJW A;  4BUD A;  1A26 A;  4HLM A;  4HLH A;  4N4V A;  4L0T A;  4UW1 A;  2QF1 A;  3UDD A;  4L10 A;  4BU9 A;  1KHB A;  5C5R A;  3GOY A;  2RKE A;  4JNG A;  4TOR A;  4BUT A;  4RV6 A;  5ECE A;  5ADS A;  2FAF A;  3UA9 A;  4GMZ A;  4BUF A;  4MT9 A;  5AKU A;  4L34 A;  5LXP A;  2PXZ X;  4PNL A;  5DCZ A;  4UVO A;  1UK0 A;  3KR8 A;  1M51 A;  4HLG A;  4J3L A;  4KZU A;  4LI7 A;  4PNM A;  4PJT A;  4BJB A;  1YVY A;  4N4T A;  4BU3 A;  5FH3 A;  4L2K A;  4PNN A;  4ZZX A;  4L7N A;  4TK0 A;  4TKF A;  4L2G A;  4BUI A;  5AL1 A;  1GS0 A;  4F1Q A;  3KR7 A;  5AL5 A;  4BGP A;  4MSK A;  3DT2 A;  4TJU A;  4GV2 A;  4BUX A;  3UH4 A;  2OLR A;  4F1L A;  3P0P A;  4UI3 A;  4BUE A;  2RKD A;  4WOU A;  4YW8 A;  4UVY A;  4GMW A;  4BJ9 A;  3DT4 A;  2X5Y A;  4L70 A;  5FH0 A;  3BLJ A;  1OEN A;  5ADT A;  3KJD A;  4BU6 A;  2PAX A;  4PNT A;  4F0E A;  5LYH A;  5C5Q A;  1YLH A;  4BUU A;  4PAX A;  4HKN A;  4IDX A;  4OA7 A;  4J1Z A;  4HHY A;  4PNQ A;  3P0Q A;  1XKV A;  4OPX C;  4R43 A;  4R6E A;  4L0V A;  4UND A;  5FH1 A;  4UVL A;  4UVT A;  4J1G A;  4N3R A;  1KHG A;  2PC9 A;  4UXB A;  2FAH A;  1KHF A;  4UVW A;  2RK7 A;  5FPG A;  3SE2 A;  3MHK A;  1K3C A;  4BJC A;  2OLQ A;  3PAX A;  4YWB A;  4GV4 A;  4BFP A;  3GN7 A;  4L6Z A;  4UVN A;  4ZZY A;  4L7R A;  4L2F A;  4UVX A;  4L31 A;  4UUH A;  4L0I A;  4L33 A;  4UI6 A;  1AYL A;  1PAX A;  4X52 A;  4I9I A;  4PJV A;  4GNM A;  5A00 A;  4TK5 A;  4TKI A;  4UVU A;  4GNO A;  3MOH A;  4UFU A;  4KRS A;  1EFY A;  4TKG A;  4HHZ A;  4YW9 A;  3C49 A;  3MHJ A;  4KZQ A;  4W5S A;  4LI8 A;  4W5I A;  3W51 A;  2GMV A;  5AKW A;  4HLK A;  4BUV A;  5FH4 A;  4HMH A;  4L7L A;  4UVV A;  4W6E A;  1AQ2 A;  4TJW A;  4TOS A;  4HLF A;  4UFY A;  3C4H A;  4GNL A;  4LI6 A;  4MSG A;  2QZY A;  4PML A;  4L6S A;  3GEY A;  4GV0 A;  2RKA A;  4WIU A;  3HKV A;  4DQY C;  4HKI A;  4J3M A;  2PAW A;  4UVP A;  3L3L A;  1K3D A;  4TJY A;  1YTM A;  1II2 A;  1OS1 A;  5C5P A;  4HYF A;  4BU7 A;  4HKK A;  3SMJ A;  4IUE A;  1NHX A;  4IJS A;  4PNR A;  4L0B A;  5EBT A;  3P0N A;  4OX2 A;  4RCG A;  4WPT A;  5AL2 A;  2RD6 A;  1WOK A;  5FH5 A;  4KZL A;  4HL5 A;  4UI5 A;  4L0S A;  4UI7 A;  4J21 A;  4BUY A;  2RK8 A;  3UH2 A;  3U9H A;  4WL8 A;  5LX6 A;  4BHH B;  1UK1 A;  4YWD A;  4BS4 A;  4OQA C;  4XHU A;  4BUS A;  2ZCI A;  4WPV A;  5AL3 A;  3DTB A;  3L3M A;  4L7P A;  4TVJ A;  4GMU A;  4AVU A;  4UHG A;  4L09 A;  4GNQ A;  2PQF A;  3U9Y A;  4BUA A;  3CE0 A;  5AL4 A;  4OQB C;  4L32 A;  2RCW A;  4GMM A;  4UVS A;  4IDU A;  4UI8 A;  4BU8 A;  4L7U A;  4DVI A;  4IDU B;  1KHE A;  4PNS A;  4WPU A;  4ZZZ A;  5AEH A;  4BUW A;  4J22 A;  4AVW A;  3KCZ A;  4BU5 A;  3MOE A;  5FPF A;  4UI4 A;  2PY7 X;  4GV7 A;  4J1J A;  5I67 A;  3FHB A;  2RF5 A;  4GNP A;  3MOF A;  2QF2 A;  4M7B A;  3DT7 A;  3ZLA A;  4U6A A;  2QEY A;  5FH2 A;  3ZL9 A; 
#chains in the Genus database with same CATH homology
 4ZZX A;  4L7N A;  4TK0 A;  1PAX A;  4TKF A;  4L2G A;  2QEW A;  4BUI A;  5AL1 A;  4HL5 A;  4UI5 A;  4X52 A;  1GS0 A;  4I9I A;  4L7O A;  4PJV A;  4L0S A;  4GNM A;  3KR7 A;  5A00 A;  4UI7 A;  5AL5 A;  5ETY A;  4MSK A;  4J21 A;  4BUY A;  4TK5 A;  3DT2 A;  4TJU A;  4TKI A;  4GV2 A;  4BUX A;  4UVU A;  2RK8 A;  4R5W A;  4GNO A;  3UH2 A;  3UH4 A;  2OLR A;  3MOH A;  4UFU A;  4F1L A;  3P0P A;  3U9H A;  4UI3 A;  4KRS A;  1EFY A;  4WIE A;  4WL8 A;  4TKG A;  4BUE A;  5LX6 A;  2RKD A;  5ADR A;  4K4E A;  4HHZ A;  4YW9 A;  5ADQ A;  4PY4 A;  4WOU A;  3C49 A;  3MHJ A;  4KZQ A;  1UK1 A;  4LI8 A;  1YGG A;  4UVY A;  4W5I A;  4GMW A;  4W5S A;  2GMV A;  4YW8 A;  4YWD A;  3W51 A;  4UVZ A;  5AKW A;  4BJ9 A;  4HLK A;  4BUV A;  4K4F A;  1J3B A;  4UX4 A;  5FH4 A;  4HMH A;  4L7L A;  4UVV A;  4W6E A;  3SMI A;  4BS4 A;  3DT4 A;  4OQA C;  4TJW A;  1AQ2 A;  4XHU A;  2X5Y A;  4BUS A;  4L70 A;  2ZCI A;  4TOS A;  5FH0 A;  4WPV A;  5AL3 A;  4HLF A;  3DTB A;  3BLJ A;  3GJW A;  3L3M A;  1OEN A;  5ADT A;  4UFY A;  3C4H A;  4BUD A;  4L7P A;  1A26 A;  3KJD A;  4TVJ A;  4GNL A;  4GMU A;  4LI6 A;  4HLM A;  4AVU A;  4UHG A;  4MSG A;  4HLH A;  2QZY A;  2PAX A;  4N4V A;  4PML A;  4BU6 A;  4PNT A;  4F0E A;  5LYH A;  4L09 A;  4L6S A;  4GNQ A;  4L0T A;  5C5Q A;  3GEY A;  1YLH A;  4UW1 A;  4BUU A;  2QF1 A;  3UDD A;  2PQF A;  4GV0 A;  2RKA A;  4WIU A;  3HKV A;  4PAX A;  3U9Y A;  4DQY C;  4BUA A;  4L10 A;  4HKN A;  4HKI A;  4BU9 A;  3CE0 A;  4PNN A;  5AL4 A;  4OA7 A;  4OQB C;  4J3M A;  1KHB A;  4J1Z A;  5C5R A;  4HHY A;  3GOY A;  2RKE A;  4L32 A;  4PNQ A;  2RCW A;  2PAW A;  3P0Q A;  1XKV A;  4OPX C;  4UVP A;  4GMM A;  4UVS A;  3L3L A;  4R43 A;  1K3D A;  4R6E A;  4TOR A;  4UI8 A;  4L0V A;  4UND A;  4BU8 A;  4L7U A;  4L0I A;  4RV6 A;  5FH1 A;  4BUT A;  5ECE A;  4DVI A;  4UVL A;  5ADS A;  4TJY A;  1KHE A;  4UVT A;  2FAF A;  1YTM A;  4PNS A;  4N3R A;  4WPU A;  4ZZZ A;  3UA9 A;  4F1Q A;  4GMZ A;  1II2 A;  1OS1 A;  5AEH A;  4BUW A;  4J22 A;  1KHG A;  4BUF A;  2PC9 A;  4AVW A;  4MT9 A;  4UXB A;  3KCZ A;  4BU5 A;  3MOE A;  5AKU A;  5FPF A;  2FAH A;  4L34 A;  1KHF A;  4UI4 A;  5C5P A;  4UVW A;  4HYF A;  4BU7 A;  2PXZ X;  4HKK A;  3SMJ A;  5LXP A;  4IUE A;  2PY7 X;  2RK7 A;  1NHX A;  4PNL A;  5DCZ A;  4UVO A;  5FPG A;  1UK0 A;  4GV7 A;  3KR8 A;  3SE2 A;  3MHK A;  1K3C A;  3FHB A;  2RF5 A;  4BJC A;  5I67 A;  4GNP A;  1M51 A;  4PNR A;  3MOF A;  2QF2 A;  4L0B A;  4M7B A;  4HLG A;  4J3L A;  2OLQ A;  3P0N A;  3PAX A;  4KZU A;  5EBT A;  4GV4 A;  4OX2 A;  4YWB A;  4LI7 A;  4BFP A;  4RCG A;  4PNM A;  3GN7 A;  4L6Z A;  4PJT A;  4UVN A;  3DT7 A;  4ZZY A;  4L7R A;  4L2F A;  4WPT A;  1YVY A;  5AL2 A;  4BJB A;  4N4T A;  4U6A A;  2RD6 A;  4BU3 A;  2QEY A;  4UVX A;  4L31 A;  4UUH A;  5FH2 A;  4L2K A;  5FH3 A;  1WOK A;  5FH5 A;  4KZL A;  4L33 A;  4UI6 A;  1AYL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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