4OPXC

Structure of human parp-1 bound to a dna double strand break in complex with (2r)-5-fluoro-2-methyl-2,3-dihydro-1-benzofuran-7-carboxamide
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
481
structure length
456
Chain Sequence
AAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Discovery and Structure-Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2H)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors.
pubmed doi rcsb
molecule keywords Poly [ADP-ribose] polymerase 1
molecule tags Transferase/dna/transferase inhibitor
source organism Homo sapiens
total genus 110
structure length 456
sequence length 481
chains with identical sequence F
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2014-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00644 PARP Poly(ADP-ribose) polymerase catalytic domain
C PF02877 PARP_reg Poly(ADP-ribose) polymerase, regulatory domain
C PF05406 WGR WGR domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.142.10 Mainly Alpha Up-down Bundle Poly(ADP-ribose) Polymerase; domain 1 Poly(ADP-ribose) polymerase, regulatory domain 4opxC03
2.20.140.10 Mainly Beta Single Sheet q64v53_bacfr protein fold WGR domain 4opxC01
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 4opxC02
4TVJA 4TK5A 4BUYA 4GV0A 4L7NA 1EFYA 4L0VA 4TKGA 4OQBC 4F0EA 4LI7A 4L10A 2PAWA 5FPFA 3HKVA 4UVZA 3KJDA 4OPXC 4PNQA 4L7LA 4M7BA 4L7UA 4R6EA 2RCWA 5AEHA 4R5WA 4OA7A 4UI3A 4MSGA 3UDDA 4TJUA 4MT9A 5ECEA 1GS0A 1WOKA 4W5SA 4BU3A 4BJCA 4UI8A 4UVTA 4UVWA 4UI6A 4HLHA 4L6ZA 4KRSA 5DCZA 4UX4A 4HYFA 4KZLA 4PY4A 3C4HA 4PNLA 4TKFA 3PAXA 4KZQA 4L70A 3KCZA 4BUEA 4HKNA 4BUVA 4PNNA 4BFPA 4BUSA 5AL4A 4L34A 5LX6A 4DVIA 4UVYA 3MHJA 4L0IA 4L0BA 4ZZYA 4BUUA 1A26A 4J3LA 4TKIA 4UFUA 5C5PA 4L2FA 4J1ZA 4UFYA 5AL3A 4BJ9A 2PAXA 4HL5A 4RV6A 4L7RA 3C49A 4BUDA 4J22A 5ETYA 4UXBA 5ADRA 5LYHA 4UW1A 2EOCA 4L0TA 4L7PA 4HLGA 4HMHA 4HKIA 1UK1A 4ZZZA 4BUTA 5FPGA 4N4VA 4L7OA 4BUAA 3KR8A 4XHUA 4J3MA 4AVWA 3UH4A 3FHBA 4K4FA 4HHYA 5AL1A 4W6EA 4UVNA 4HLFA 4UVVA 4BUFA 2PQFA 4L32A 3L3LA 4N4TA 5C5RA 4UVUA 4F1QA 3GJWA 5LXPA 4IUEA 4L09A 4PAXA 4BU9A 4UVPA 4UVSA 3SMIA 4DQYC 3P0QA 4PNTA 3UA9A 3P0PA 4OQAC 4PNRA 3U9HA 3SE2A 4TJWA 4BUXA 4HLMA 4GV7A 2RD6A 4HKKA 3UH2A 3GEYA 4TJYA 5A00A 3GN7A 4UVXA 5ADSA 4UVOA 5ADTA 1PAXA 3CE0A 4UHGA 4ZZXA 4L31A 4PJTA 4U6AA 3BLJA 4BJBA 4X52A 3KR7A 4K4EA 4MSKA 4I9IA 4BU7A 4KZUA 4HLKA 3L3MA 4BU5A 4L0SA 5AL5A 4PNMA 4HHZA 4LI6A 4PMLA 4N3RA 4W5IA 5EBTA 3SMJA 2X5YA 3U9YA 3MHKA 5ADQA 4UVLA 5AKWA 3GOYA 4BS4A 3W51A 4L2GA 4BU8A 4L33A 4PNSA 4TORA 5AL2A 2RA8A 4UI7A 4AVUA 4BUWA 4TK0A 4BU6A 2CR9A 4UI5A 5C5QA 4BUIA 4UNDA 4F1LA 4GV4A 2RF5A 4PJVA 5AKUA 1UK0A 3P0NA 4L2KA 4L6SA 4UUHA 4J21A 4GV2A 4UI4A 4TOSA 4LI8A
chains in the Genus database with same CATH superfamily
4L0VA 1EFYA 4LI7A 4L10A 2PAWA 3KJDA 4OPXC 5FH2A 1KHFA 3MOFA 4R6EA 5AEHA 2GMVA 4WL8A 4R5WA 3MOEA 1GS0A 4BU3A 3DT4A 4HLHA 4L6ZA 4KRSA 4KZQA 4BUSA 4BHHB 4GMUA 4ZZYA 4J3LA 5C5PA 4J1ZA 4L7RA 3C49A 4BUDA 5ETYA 4UXBA 2QEWA 4L7PA 4J1JA 4HKIA 4ZZZA 4BUTA 5FPGA 4BUAA 4AVWA 2PC9A 3UH4A 3DT7A 5AL1A 4W6EA 4HLFA 4IUEA 4IDXA 4GNOA 2RK7A 3SMIA 4DQYC 3P0QA 4PNTA 4TJWA 4BUXA 5A00A 4GMZA 2PY7X 4U6AA 4GMWA 4YWBA 4BU7A 4HHZA 4W5IA 3SMJA 3U9YA 4UVLA 4BS4A 3W51A 4AVUA 4TK0A 4BU6A 4UNDA 2RF5A 4L6SA 4L7NA 2OLQA 4TKGA 5FH1A 4OQBC 4GNPA 4WIEA 3HKVA 4WPUA 4L7UA 2RCWA 5FH3A 4OA7A 4UI3A 4MSGA 4MT9A 2QEYA 4W5SA 4UI8A 4UI6A 5DCZA 4KZLA 3C4HA 3PAXA 4L70A 1M51A 4BUVA 2RKDA 5LX6A 4DVIA 4UVYA 4L0BA 4L2FA 4UFYA 2PAXA 4HL5A 5I67A 4N4VA 1K3DA 3FHBA 4UVNA 4BUFA 2PQFA 4N4TA 5C5RA 2RKEA 4R43A 2HZMA 4YW8A 4UVPA 3UA9A 3P0PA 4PNRA 3U9HA 3SE2A 4GNLA 3GN7A 3CE0A 4UHGA 4ZZXA 3MOHA 4PJTA 4YWDA 4BJBA 3KR7A 4GNMA 4MSKA 2FAFA 4BU5A 4PMLA 4N3RA 2X5YA 3GOYA 4L2GA 4BU8A 4TORA 4BUWA 1J3BA 2CR9A 4BUIA 4WPTA 4GV4A 5AKUA 1UK0A 4YW9A 3P0NA 4UUHA 4TOSA 4TVJA 4BUYA 4F0EA 5FPFA 4UVZA 4PNQA 4L7LA 4M7BA 1YLHA 5ECEA 1WOKA 4BGPA 4UVTA 2OLRA 2HZSA 4WOUA 4PY4A 4BUEA 4PNLA 4PNNA 5AL4A 3ZL9A 3MHJA 5FH0A 4IJSA 4OX2A 1A26A 3DT2A 4TKIA 1KHGA 2FAHA 4J22A 2RK8A 2QF1A 4UW1A 4HLGA 4HMHA 1UK1A 3KR8A 4XHUA 1NHXA 4L32A 4F1QA 4BU9A 4PAXA 4WPVA 1YVYA 4HLMA 4UVXA 4TJYA 5ADSA 4UVOA 1PAXA 4L31A 4IDUA 2QF2A 1XKVA 4KZUA 4HLKA 5ADQA 1KHEA 1KHBA 4PNSA 4JNGA 5AL2A 5C5QA 1YTMA 4F1LA 4PJVA 4L2KA 1K3CA 4LI8A 4TK5A 1AQ2A 4GV0A 1OS1A 2QZYA 3UDDA 2RKAA 4TJUA 1II2A 4GNQA 4BJCA 4UVWA 5FH5A 2PXZX 4UX4A 4HYFA 4TKFA 3KCZA 4HKNA 4BFPA 4L34A 1AYLA 4L0IA 4BUUA 3ZLAA 4UFUA 5AL3A 4BJ9A 4RV6A 5LYHA 5ADRA 2EOCA 4L0TA 4L7OA 4J3MA 4K4FA 4HHYA 4UVVA 3L3LA 5LXPA 4UVUA 3GJWA 4L09A 4UVSA 1OENA 4GMMA 4OQAC 4GV7A 2RD6A 1YGGA 4HKKA 3GEYA 3UH2A 5ADTA 4IDUB 4WIUA 3BLJA 4X52A 4K4EA 4I9IA 3L3MA 4L0SA 5AL5A 4PNMA 5EBTA 4LI6A 3MHKA 2ZCIA 5AKWA 4L33A 2RA8A 4UI7A 4UI5A 4J1GA 5FH4A 4J21A 4GV2A 4UI4A 3DTBA 4RCGA
chains in the Genus database with same CATH topology
4L0VA 1EFYA 4LI7A 4L10A 2PAWA 3KJDA 4OPXC 5FH2A 1KHFA 3MOFA 4R6EA 5AEHA 2GMVA 4WL8A 4R5WA 3MOEA 1GS0A 4BU3A 3DT4A 4HLHA 4L6ZA 4KRSA 4KZQA 4BUSA 4GMUA 4ZZYA 4J3LA 5C5PA 4J1ZA 4L7RA 3C49A 4BUDA 5ETYA 4UXBA 2QEWA 4L7PA 4HKIA 4ZZZA 4BUTA 5FPGA 4BUAA 4AVWA 2PC9A 3UH4A 3DT7A 5AL1A 4W6EA 4HLFA 4IUEA 4GNOA 2RK7A 3SMIA 4DQYC 3P0QA 4PNTA 4TJWA 4BUXA 5A00A 4GMZA 2PY7X 4U6AA 4GMWA 4YWBA 4BU7A 4HHZA 4W5IA 3SMJA 3U9YA 4UVLA 4BS4A 3W51A 4AVUA 4TK0A 4BU6A 4UNDA 2RF5A 4L6SA 4L7NA 2OLQA 4TKGA 5FH1A 4OQBC 4GNPA 4WIEA 3HKVA 4WPUA 4L7UA 2RCWA 5FH3A 4OA7A 4UI3A 4MSGA 4MT9A 2QEYA 4W5SA 4UI8A 4UI6A 5DCZA 4KZLA 3C4HA 3PAXA 4L70A 1M51A 4BUVA 2RKDA 5LX6A 4DVIA 4UVYA 4L0BA 4L2FA 4UFYA 2PAXA 4HL5A 5I67A 4N4VA 1K3DA 3FHBA 4UVNA 4BUFA 2PQFA 4N4TA 5C5RA 2RKEA 4R43A 4YW8A 4UVPA 3UA9A 3P0PA 4PNRA 3U9HA 3SE2A 4GNLA 3GN7A 3CE0A 4UHGA 4ZZXA 3MOHA 4PJTA 4YWDA 4BJBA 3KR7A 4GNMA 4MSKA 2FAFA 4BU5A 4PMLA 4N3RA 2X5YA 3GOYA 4L2GA 4BU8A 4TORA 4BUWA 1J3BA 2CR9A 4BUIA 4WPTA 4GV4A 5AKUA 1UK0A 4YW9A 3P0NA 4UUHA 4TOSA 4TVJA 4BUYA 4F0EA 5FPFA 4UVZA 4PNQA 4L7LA 4M7BA 1YLHA 5ECEA 1WOKA 4UVTA 2OLRA 4WOUA 4PY4A 4BUEA 4PNLA 4PNNA 5AL4A 3MHJA 5FH0A 4OX2A 1A26A 3DT2A 4TKIA 1KHGA 2FAHA 4J22A 2RK8A 2QF1A 4UW1A 4HLGA 4HMHA 1UK1A 3KR8A 4XHUA 1NHXA 4L32A 4F1QA 4BU9A 4PAXA 4WPVA 1YVYA 4HLMA 4UVXA 4TJYA 5ADSA 4UVOA 1PAXA 4L31A 2QF2A 1XKVA 4KZUA 4HLKA 5ADQA 1KHEA 1KHBA 4PNSA 5AL2A 5C5QA 1YTMA 4F1LA 4PJVA 4L2KA 1K3CA 4LI8A 4TK5A 1AQ2A 4GV0A 1OS1A 2QZYA 3UDDA 2RKAA 4TJUA 1II2A 4GNQA 4BJCA 4UVWA 5FH5A 2PXZX 4UX4A 4HYFA 4TKFA 3KCZA 4HKNA 4BFPA 4L34A 1AYLA 4L0IA 4BUUA 4UFUA 5AL3A 4BJ9A 4RV6A 5LYHA 5ADRA 2EOCA 4L0TA 4L7OA 4J3MA 4K4FA 4HHYA 4UVVA 3L3LA 5LXPA 4UVUA 3GJWA 4L09A 4UVSA 1OENA 4GMMA 4OQAC 4GV7A 2RD6A 1YGGA 4HKKA 3GEYA 3UH2A 5ADTA 4WIUA 3BLJA 4X52A 4K4EA 4I9IA 3L3MA 4L0SA 5AL5A 4PNMA 5EBTA 4LI6A 3MHKA 2ZCIA 5AKWA 4L33A 2RA8A 4UI7A 4UI5A 5FH4A 4J21A 4GV2A 4UI4A 3DTBA 4RCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TVJ A;  4TK5 A;  4BUY A;  4GV0 A;  4L7N A;  1EFY A;  4L0V A;  4TKG A;  4OQB C;  4F0E A;  4LI7 A;  4L10 A;  2PAW A;  5FPF A;  3HKV A;  4UVZ A;  3KJD A;  4OPX C;  4PNQ A;  4L7L A;  4M7B A;  4L7U A;  4R6E A;  2RCW A;  5AEH A;  4R5W A;  4OA7 A;  4UI3 A;  4MSG A;  3UDD A;  4TJU A;  4MT9 A;  5ECE A;  1GS0 A;  1WOK A;  4W5S A;  4BU3 A;  4BJC A;  4UI8 A;  4UVT A;  4UVW A;  4UI6 A;  4HLH A;  4L6Z A;  4KRS A;  5DCZ A;  4UX4 A;  4HYF A;  4KZL A;  4PY4 A;  3C4H A;  4PNL A;  4TKF A;  3PAX A;  4KZQ A;  4L70 A;  3KCZ A;  4BUE A;  4HKN A;  4BUV A;  4PNN A;  4BFP A;  4BUS A;  5AL4 A;  4L34 A;  5LX6 A;  4DVI A;  4UVY A;  3MHJ A;  4L0I A;  4L0B A;  4ZZY A;  4BUU A;  1A26 A;  4J3L A;  4TKI A;  4UFU A;  5C5P A;  4L2F A;  4J1Z A;  4UFY A;  5AL3 A;  4BJ9 A;  2PAX A;  4HL5 A;  4RV6 A;  4L7R A;  3C49 A;  4BUD A;  4J22 A;  5ETY A;  4UXB A;  5ADR A;  5LYH A;  4UW1 A;  2EOC A;  4L0T A;  4L7P A;  4HLG A;  4HMH A;  4HKI A;  1UK1 A;  4ZZZ A;  4BUT A;  5FPG A;  4N4V A;  4L7O A;  4BUA A;  3KR8 A;  4XHU A;  4J3M A;  4AVW A;  3UH4 A;  3FHB A;  4K4F A;  4HHY A;  5AL1 A;  4W6E A;  4UVN A;  4HLF A;  4UVV A;  4BUF A;  2PQF A;  4L32 A;  3L3L A;  4N4T A;  5C5R A;  4UVU A;  4F1Q A;  3GJW A;  5LXP A;  4IUE A;  4L09 A;  4PAX A;  4BU9 A;  4UVP A;  4UVS A;  3SMI A;  4DQY C;  3P0Q A;  4PNT A;  3UA9 A;  3P0P A;  4OQA C;  4PNR A;  3U9H A;  3SE2 A;  4TJW A;  4BUX A;  4HLM A;  4GV7 A;  2RD6 A;  4HKK A;  3UH2 A;  3GEY A;  4TJY A;  5A00 A;  3GN7 A;  4UVX A;  5ADS A;  4UVO A;  5ADT A;  1PAX A;  3CE0 A;  4UHG A;  4ZZX A;  4L31 A;  4PJT A;  4U6A A;  3BLJ A;  4BJB A;  4X52 A;  3KR7 A;  4K4E A;  4MSK A;  4I9I A;  4BU7 A;  4KZU A;  4HLK A;  3L3M A;  4BU5 A;  4L0S A;  5AL5 A;  4PNM A;  4HHZ A;  4LI6 A;  4PML A;  4N3R A;  4W5I A;  5EBT A;  3SMJ A;  2X5Y A;  3U9Y A;  3MHK A;  5ADQ A;  4UVL A;  5AKW A;  3GOY A;  4BS4 A;  3W51 A;  4L2G A;  4BU8 A;  4L33 A;  4PNS A;  4TOR A;  5AL2 A;  2RA8 A;  4UI7 A;  4AVU A;  4BUW A;  4TK0 A;  4BU6 A;  2CR9 A;  4UI5 A;  5C5Q A;  4BUI A;  4UND A;  4F1L A;  4GV4 A;  2RF5 A;  4PJV A;  5AKU A;  1UK0 A;  3P0N A;  4L2K A;  4L6S A;  4UUH A;  4J21 A;  4GV2 A;  4UI4 A;  4TOS A;  4LI8 A; 
#chains in the Genus database with same CATH topology
 4L0V A;  1EFY A;  4LI7 A;  4L10 A;  2PAW A;  3KJD A;  4OPX C;  5FH2 A;  1KHF A;  3MOF A;  4R6E A;  5AEH A;  2GMV A;  4WL8 A;  4R5W A;  3MOE A;  1GS0 A;  4BU3 A;  3DT4 A;  4HLH A;  4L6Z A;  4KRS A;  4KZQ A;  4BUS A;  4BHH B;  4GMU A;  4ZZY A;  4J3L A;  5C5P A;  4J1Z A;  4L7R A;  3C49 A;  4BUD A;  5ETY A;  4UXB A;  2QEW A;  4L7P A;  4J1J A;  4HKI A;  4ZZZ A;  4BUT A;  5FPG A;  4BUA A;  4AVW A;  2PC9 A;  3UH4 A;  3DT7 A;  5AL1 A;  4W6E A;  4HLF A;  4IUE A;  4IDX A;  4GNO A;  2RK7 A;  3SMI A;  4DQY C;  3P0Q A;  4PNT A;  4TJW A;  4BUX A;  5A00 A;  4GMZ A;  2PY7 X;  4U6A A;  4GMW A;  4YWB A;  4BU7 A;  4HHZ A;  4W5I A;  3SMJ A;  3U9Y A;  4UVL A;  4BS4 A;  3W51 A;  4AVU A;  4TK0 A;  4BU6 A;  4UND A;  2RF5 A;  4L6S A;  4L7N A;  2OLQ A;  4TKG A;  5FH1 A;  4OQB C;  4GNP A;  4WIE A;  3HKV A;  4WPU A;  4L7U A;  2RCW A;  5FH3 A;  4OA7 A;  4UI3 A;  4MSG A;  4MT9 A;  2QEY A;  4W5S A;  4UI8 A;  4UI6 A;  5DCZ A;  4KZL A;  3C4H A;  3PAX A;  4L70 A;  1M51 A;  4BUV A;  2RKD A;  5LX6 A;  4DVI A;  4UVY A;  4L0B A;  4L2F A;  4UFY A;  2PAX A;  4HL5 A;  5I67 A;  4N4V A;  1K3D A;  3FHB A;  4UVN A;  4BUF A;  2PQF A;  4N4T A;  5C5R A;  2RKE A;  4R43 A;  2HZM A;  4YW8 A;  4UVP A;  3UA9 A;  3P0P A;  4PNR A;  3U9H A;  3SE2 A;  4GNL A;  3GN7 A;  3CE0 A;  4UHG A;  4ZZX A;  3MOH A;  4PJT A;  4YWD A;  4BJB A;  3KR7 A;  4GNM A;  4MSK A;  2FAF A;  4BU5 A;  4PML A;  4N3R A;  2X5Y A;  3GOY A;  4L2G A;  4BU8 A;  4TOR A;  4BUW A;  1J3B A;  2CR9 A;  4BUI A;  4WPT A;  4GV4 A;  5AKU A;  1UK0 A;  4YW9 A;  3P0N A;  4UUH A;  4TOS A;  4TVJ A;  4BUY A;  4F0E A;  5FPF A;  4UVZ A;  4PNQ A;  4L7L A;  4M7B A;  1YLH A;  5ECE A;  1WOK A;  4BGP A;  4UVT A;  2OLR A;  2HZS A;  4WOU A;  4PY4 A;  4BUE A;  4PNL A;  4PNN A;  5AL4 A;  3ZL9 A;  3MHJ A;  5FH0 A;  4IJS A;  4OX2 A;  1A26 A;  3DT2 A;  4TKI A;  1KHG A;  2FAH A;  4J22 A;  2RK8 A;  2QF1 A;  4UW1 A;  4HLG A;  4HMH A;  1UK1 A;  3KR8 A;  4XHU A;  1NHX A;  4L32 A;  4F1Q A;  4BU9 A;  4PAX A;  4WPV A;  1YVY A;  4HLM A;  4UVX A;  4TJY A;  5ADS A;  4UVO A;  1PAX A;  4L31 A;  4IDU A;  2QF2 A;  1XKV A;  4KZU A;  4HLK A;  5ADQ A;  1KHE A;  1KHB A;  4PNS A;  4JNG A;  5AL2 A;  5C5Q A;  1YTM A;  4F1L A;  4PJV A;  4L2K A;  1K3C A;  4LI8 A;  4TK5 A;  1AQ2 A;  4GV0 A;  1OS1 A;  2QZY A;  3UDD A;  2RKA A;  4TJU A;  1II2 A;  4GNQ A;  4BJC A;  4UVW A;  5FH5 A;  2PXZ X;  4UX4 A;  4HYF A;  4TKF A;  3KCZ A;  4HKN A;  4BFP A;  4L34 A;  1AYL A;  4L0I A;  4BUU A;  3ZLA A;  4UFU A;  5AL3 A;  4BJ9 A;  4RV6 A;  5LYH A;  5ADR A;  2EOC A;  4L0T A;  4L7O A;  4J3M A;  4K4F A;  4HHY A;  4UVV A;  3L3L A;  5LXP A;  4UVU A;  3GJW A;  4L09 A;  4UVS A;  1OEN A;  4GMM A;  4OQA C;  4GV7 A;  2RD6 A;  1YGG A;  4HKK A;  3GEY A;  3UH2 A;  5ADT A;  4IDU B;  4WIU A;  3BLJ A;  4X52 A;  4K4E A;  4I9I A;  3L3M A;  4L0S A;  5AL5 A;  4PNM A;  5EBT A;  4LI6 A;  3MHK A;  2ZCI A;  5AKW A;  4L33 A;  2RA8 A;  4UI7 A;  4UI5 A;  4J1G A;  5FH4 A;  4J21 A;  4GV2 A;  4UI4 A;  3DTB A;  4RCG A; 
#chains in the Genus database with same CATH homology
 4L0V A;  1EFY A;  4LI7 A;  4L10 A;  2PAW A;  3KJD A;  4OPX C;  5FH2 A;  1KHF A;  3MOF A;  4R6E A;  5AEH A;  2GMV A;  4WL8 A;  4R5W A;  3MOE A;  1GS0 A;  4BU3 A;  3DT4 A;  4HLH A;  4L6Z A;  4KRS A;  4KZQ A;  4BUS A;  4GMU A;  4ZZY A;  4J3L A;  5C5P A;  4J1Z A;  4L7R A;  3C49 A;  4BUD A;  5ETY A;  4UXB A;  2QEW A;  4L7P A;  4HKI A;  4ZZZ A;  4BUT A;  5FPG A;  4BUA A;  4AVW A;  2PC9 A;  3UH4 A;  3DT7 A;  5AL1 A;  4W6E A;  4HLF A;  4IUE A;  4GNO A;  2RK7 A;  3SMI A;  4DQY C;  3P0Q A;  4PNT A;  4TJW A;  4BUX A;  5A00 A;  4GMZ A;  2PY7 X;  4U6A A;  4GMW A;  4YWB A;  4BU7 A;  4HHZ A;  4W5I A;  3SMJ A;  3U9Y A;  4UVL A;  4BS4 A;  3W51 A;  4AVU A;  4TK0 A;  4BU6 A;  4UND A;  2RF5 A;  4L6S A;  4L7N A;  2OLQ A;  4TKG A;  5FH1 A;  4OQB C;  4GNP A;  4WIE A;  3HKV A;  4WPU A;  4L7U A;  2RCW A;  5FH3 A;  4OA7 A;  4UI3 A;  4MSG A;  4MT9 A;  2QEY A;  4W5S A;  4UI8 A;  4UI6 A;  5DCZ A;  4KZL A;  3C4H A;  3PAX A;  4L70 A;  1M51 A;  4BUV A;  2RKD A;  5LX6 A;  4DVI A;  4UVY A;  4L0B A;  4L2F A;  4UFY A;  2PAX A;  4HL5 A;  5I67 A;  4N4V A;  1K3D A;  3FHB A;  4UVN A;  4BUF A;  2PQF A;  4N4T A;  5C5R A;  2RKE A;  4R43 A;  4YW8 A;  4UVP A;  3UA9 A;  3P0P A;  4PNR A;  3U9H A;  3SE2 A;  4GNL A;  3GN7 A;  3CE0 A;  4UHG A;  4ZZX A;  3MOH A;  4PJT A;  4YWD A;  4BJB A;  3KR7 A;  4GNM A;  4MSK A;  2FAF A;  4BU5 A;  4PML A;  4N3R A;  2X5Y A;  3GOY A;  4L2G A;  4BU8 A;  4TOR A;  4BUW A;  1J3B A;  2CR9 A;  4BUI A;  4WPT A;  4GV4 A;  5AKU A;  1UK0 A;  4YW9 A;  3P0N A;  4UUH A;  4TOS A;  4TVJ A;  4BUY A;  4F0E A;  5FPF A;  4UVZ A;  4PNQ A;  4L7L A;  4M7B A;  1YLH A;  5ECE A;  1WOK A;  4UVT A;  2OLR A;  4WOU A;  4PY4 A;  4BUE A;  4PNL A;  4PNN A;  5AL4 A;  3MHJ A;  5FH0 A;  4OX2 A;  1A26 A;  3DT2 A;  4TKI A;  1KHG A;  2FAH A;  4J22 A;  2RK8 A;  2QF1 A;  4UW1 A;  4HLG A;  4HMH A;  1UK1 A;  3KR8 A;  4XHU A;  1NHX A;  4L32 A;  4F1Q A;  4BU9 A;  4PAX A;  4WPV A;  1YVY A;  4HLM A;  4UVX A;  4TJY A;  5ADS A;  4UVO A;  1PAX A;  4L31 A;  2QF2 A;  1XKV A;  4KZU A;  4HLK A;  5ADQ A;  1KHE A;  1KHB A;  4PNS A;  5AL2 A;  5C5Q A;  1YTM A;  4F1L A;  4PJV A;  4L2K A;  1K3C A;  4LI8 A;  4TK5 A;  1AQ2 A;  4GV0 A;  1OS1 A;  2QZY A;  3UDD A;  2RKA A;  4TJU A;  1II2 A;  4GNQ A;  4BJC A;  4UVW A;  5FH5 A;  2PXZ X;  4UX4 A;  4HYF A;  4TKF A;  3KCZ A;  4HKN A;  4BFP A;  4L34 A;  1AYL A;  4L0I A;  4BUU A;  4UFU A;  5AL3 A;  4BJ9 A;  4RV6 A;  5LYH A;  5ADR A;  2EOC A;  4L0T A;  4L7O A;  4J3M A;  4K4F A;  4HHY A;  4UVV A;  3L3L A;  5LXP A;  4UVU A;  3GJW A;  4L09 A;  4UVS A;  1OEN A;  4GMM A;  4OQA C;  4GV7 A;  2RD6 A;  1YGG A;  4HKK A;  3GEY A;  3UH2 A;  5ADT A;  4WIU A;  3BLJ A;  4X52 A;  4K4E A;  4I9I A;  3L3M A;  4L0S A;  5AL5 A;  4PNM A;  5EBT A;  4LI6 A;  3MHK A;  2ZCI A;  5AKW A;  4L33 A;  2RA8 A;  4UI7 A;  4UI5 A;  5FH4 A;  4J21 A;  4GV2 A;  4UI4 A;  3DTB A;  4RCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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