2GW6A

Nmr structure of the human trna endonuclease sen15 subunit
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
123
structure length
123
Chain Sequence
SEDAWMGTHPKYLEMMELDIGDATQVYVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIREILKASRKLQGDPDLPMSFTLAIVESDSTIVYYKLTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure determined for a subunit of human tRNA splicing endonuclease (Sen15) reveals a novel dimeric fold.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords tRNA-splicing endonuclease subunit Sen15
total genus 26
structure length 123
sequence length 123
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-05-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 2gw6A01
1A79A 2ZYZA 1OB9A 2FCOA 2WCWA 3AJVA 3DNXA 1HH1A 2WIZA 2EO0A 1IPIA 1Y88A 2INBA 3P1ZB 2WJ0A 4QBNA 2ZYZB 1OB8A 1R0VA 1GEFA 2CV8A 4QBLA 5FDKA 3P1YA 1RLVA 3AJVB 4QBOA 2OSTA 2VLDA 1RZNA 1ZP7A 1Y1OA 2GW6A 1R11A 2OKFA 4TKDA 3IEYA 4TKKA 2GJWA 3P1ZA 2WIWA 1T0FA 2WCZA 1F1ZA 1XMXA 3FOVA
chains in the Genus database with same CATH superfamily
1A79A 2ZYZA 2VS1A 1OB9A 2FCOA 2WCWA 3BT7A 2FKCA 2FLCA 4LQEA 3AJVA 3DNXA 4DA2A 4EV1A 1UWVA 1HH1A 2Z0RA 2DBSA 3IEYB 2WIZA 2EO0A 2IXSA 1IPIA 1Y88A 2INBA 4G6VA 2FL3A 2CZRA 3P1ZB 2WJ0A 4QBNA 2ZYZB 1OB8A 1R0VA 1GEFA 2JJQA 2CV8A 4ZQUA 4QBLA 5FDKA 4G6UA 3P1YA 1RLVA 3AJVB 4E6ZA 4DAVA 4DAPA 4QBOA 2OSTA 2BH2A 2VLDA 1RZNA 1ZP7A 1YNMA 1Y1OA 2W8MA 2GW6A 1R11A 2OKFA 4TKDA 3IEYA 4TKKA 3IF0X 2GJWA 2FKHB 3P1ZA 2WIWA 1T0FA 2WCZA 1F1ZA 1XMXA 3FOVA
chains in the Genus database with same CATH topology
1A79A 2ZYZA 2VS1A 1OB9A 2FCOA 2WCWA 3BT7A 2FKCA 2FLCA 4LQEA 3AJVA 3DNXA 4DA2A 4EV1A 1UWVA 1HH1A 2Z0RA 2DBSA 3IEYB 2WIZA 2EO0A 2IXSA 1IPIA 1Y88A 2INBA 4G6VA 2FL3A 2CZRA 3P1ZB 2WJ0A 4QBNA 2ZYZB 1OB8A 1R0VA 1GEFA 2JJQA 2CV8A 4ZQUA 4QBLA 5FDKA 4G6UA 3P1YA 1RLVA 3AJVB 4E6ZA 4DAVA 4DAPA 4QBOA 2OSTA 2BH2A 2VLDA 1RZNA 1ZP7A 1YNMA 1Y1OA 2W8MA 2GW6A 1R11A 2OKFA 4TKDA 3IEYA 4TKKA 3IF0X 2GJWA 2FKHB 3P1ZA 2WIWA 1T0FA 2WCZA 1F1ZA 1XMXA 3FOVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A79 A;  2ZYZ A;  1OB9 A;  2FCO A;  2WCW A;  3AJV A;  3DNX A;  1HH1 A;  2WIZ A;  2EO0 A;  1IPI A;  1Y88 A;  2INB A;  3P1Z B;  2WJ0 A;  4QBN A;  2ZYZ B;  1OB8 A;  1R0V A;  1GEF A;  2CV8 A;  4QBL A;  5FDK A;  3P1Y A;  1RLV A;  3AJV B;  4QBO A;  2OST A;  2VLD A;  1RZN A;  1ZP7 A;  1Y1O A;  2GW6 A;  1R11 A;  2OKF A;  4TKD A;  3IEY A;  4TKK A;  2GJW A;  3P1Z A;  2WIW A;  1T0F A;  2WCZ A;  1F1Z A;  1XMX A;  3FOV A; 
#chains in the Genus database with same CATH topology
 1A79 A;  2ZYZ A;  2VS1 A;  1OB9 A;  2FCO A;  2WCW A;  3BT7 A;  2FKC A;  2FLC A;  4LQE A;  3AJV A;  3DNX A;  4DA2 A;  4EV1 A;  1UWV A;  1HH1 A;  2Z0R A;  2DBS A;  3IEY B;  2WIZ A;  2EO0 A;  2IXS A;  1IPI A;  1Y88 A;  2INB A;  4G6V A;  2FL3 A;  2CZR A;  3P1Z B;  2WJ0 A;  4QBN A;  2ZYZ B;  1OB8 A;  1R0V A;  1GEF A;  2JJQ A;  2CV8 A;  4ZQU A;  4QBL A;  5FDK A;  4G6U A;  3P1Y A;  1RLV A;  3AJV B;  4E6Z A;  4DAV A;  4DAP A;  4QBO A;  2OST A;  2BH2 A;  2VLD A;  1RZN A;  1ZP7 A;  1YNM A;  1Y1O A;  2W8M A;  2GW6 A;  1R11 A;  2OKF A;  4TKD A;  3IEY A;  4TKK A;  3IF0 X;  2GJW A;  2FKH B;  3P1Z A;  2WIW A;  1T0F A;  2WCZ A;  1F1Z A;  1XMX A;  3FOV A; 
#chains in the Genus database with same CATH homology
 1A79 A;  2ZYZ A;  2VS1 A;  1OB9 A;  2FCO A;  2WCW A;  3BT7 A;  2FKC A;  2FLC A;  4LQE A;  3AJV A;  3DNX A;  4DA2 A;  4EV1 A;  1UWV A;  1HH1 A;  2Z0R A;  2DBS A;  3IEY B;  2WIZ A;  2EO0 A;  2IXS A;  1IPI A;  1Y88 A;  2INB A;  4G6V A;  2FL3 A;  2CZR A;  3P1Z B;  2WJ0 A;  4QBN A;  2ZYZ B;  1OB8 A;  1R0V A;  1GEF A;  2JJQ A;  2CV8 A;  4ZQU A;  4QBL A;  5FDK A;  4G6U A;  3P1Y A;  1RLV A;  3AJV B;  4E6Z A;  4DAV A;  4DAP A;  4QBO A;  2OST A;  2BH2 A;  2VLD A;  1RZN A;  1ZP7 A;  1YNM A;  1Y1O A;  2W8M A;  2GW6 A;  1R11 A;  2OKF A;  4TKD A;  3IEY A;  4TKK A;  3IF0 X;  2GJW A;  2FKH B;  3P1Z A;  2WIW A;  1T0F A;  2WCZ A;  1F1Z A;  1XMX A;  3FOV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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