2GW6A

Nmr structure of the human trna endonuclease sen15 subunit
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
123
structure length
123
Chain Sequence
SEDAWMGTHPKYLEMMELDIGDATQVYVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIREILKASRKLQGDPDLPMSFTLAIVESDSTIVYYKLTD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Three-dimensional structure determined for a subunit of human tRNA splicing endonuclease (Sen15) reveals a novel dimeric fold.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords tRNA-splicing endonuclease subunit Sen15
total genus 26
structure length 123
sequence length 123
chains with identical sequence B
ec nomenclature
pdb deposition date 2006-05-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1350.10 Alpha Beta 3-Layer(aba) Sandwich Trna Endonuclease; Chain: A, domain 1 Trna Endonuclease; Chain: A, domain 1 2gw6A01
4TKDA 4QBOA 2OKFA 1XMXA 1F1ZA 1HH1A 1T0FA 2VLDA 2CV8A 3FOVA 3IEYA 5FDKA 2WIZA 1A79A 2ZYZA 4QBNA 1Y1OA 2GW6A 3AJVA 1ZP7A 1RZNA 1OB8A 2ZYZB 2WCWA 3AJVB 3P1ZA 4TKKA 1OB9A 3DNXA 3P1ZB 1R0VA 2GJWA 1R11A 2INBA 1GEFA 4QBLA 2WIWA 1IPIA 2WJ0A 1Y88A 2FCOA 2OSTA 1RLVA 2WCZA 2EO0A 3P1YA
chains in the Genus database with same CATH superfamily
4TKDA 4QBOA 2OKFA 1XMXA 1F1ZA 1HH1A 1T0FA 2VLDA 2CV8A 2VS1A 3FOVA 3IEYA 5FDKA 2WIZA 2FLCA 4LQEA 2FL3A 3IEYB 1A79A 2ZYZA 4QBNA 1Y1OA 2GW6A 4G6UA 4DAVA 3AJVA 1ZP7A 1RZNA 1OB8A 2ZYZB 4DA2A 2WCWA 4EV1A 2FKCA 3AJVB 3IF0X 3P1ZA 1UWVA 2BH2A 3BT7A 2DBSA 4TKKA 4G6VA 1OB9A 3DNXA 3P1ZB 4ZQUA 1R0VA 4E6ZA 2GJWA 1R11A 4DAPA 2INBA 1GEFA 4QBLA 2WIWA 2W8MA 1IPIA 2WJ0A 2JJQA 2CZRA 2IXSA 2Z0RA 1Y88A 2FCOA 2OSTA 1RLVA 2FKHB 2WCZA 2EO0A 1YNMA 3P1YA
chains in the Genus database with same CATH topology
4TKDA 4QBOA 2OKFA 1XMXA 1F1ZA 1HH1A 1T0FA 2VLDA 2CV8A 2VS1A 3FOVA 3IEYA 5FDKA 2WIZA 2FLCA 4LQEA 2FL3A 3IEYB 1A79A 2ZYZA 4QBNA 1Y1OA 2GW6A 4G6UA 4DAVA 3AJVA 1ZP7A 1RZNA 1OB8A 2ZYZB 4DA2A 2WCWA 4EV1A 2FKCA 3AJVB 3IF0X 3P1ZA 1UWVA 2BH2A 3BT7A 2DBSA 4TKKA 4G6VA 1OB9A 3DNXA 3P1ZB 4ZQUA 1R0VA 4E6ZA 2GJWA 1R11A 4DAPA 2INBA 1GEFA 4QBLA 2WIWA 2W8MA 1IPIA 2WJ0A 2JJQA 2CZRA 2IXSA 2Z0RA 1Y88A 2FCOA 2OSTA 1RLVA 2FKHB 2WCZA 2EO0A 1YNMA 3P1YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TKD A;  4QBO A;  2OKF A;  1XMX A;  1F1Z A;  1HH1 A;  1T0F A;  2VLD A;  2CV8 A;  3FOV A;  3IEY A;  5FDK A;  2WIZ A;  1A79 A;  2ZYZ A;  4QBN A;  1Y1O A;  2GW6 A;  3AJV A;  1ZP7 A;  1RZN A;  1OB8 A;  2ZYZ B;  2WCW A;  3AJV B;  3P1Z A;  4TKK A;  1OB9 A;  3DNX A;  3P1Z B;  1R0V A;  2GJW A;  1R11 A;  2INB A;  1GEF A;  4QBL A;  2WIW A;  1IPI A;  2WJ0 A;  1Y88 A;  2FCO A;  2OST A;  1RLV A;  2WCZ A;  2EO0 A;  3P1Y A; 
#chains in the Genus database with same CATH topology
 4TKD A;  4QBO A;  2OKF A;  1XMX A;  1F1Z A;  1HH1 A;  1T0F A;  2VLD A;  2CV8 A;  2VS1 A;  3FOV A;  3IEY A;  5FDK A;  2WIZ A;  2FLC A;  4LQE A;  2FL3 A;  3IEY B;  1A79 A;  2ZYZ A;  4QBN A;  1Y1O A;  2GW6 A;  4G6U A;  4DAV A;  3AJV A;  1ZP7 A;  1RZN A;  1OB8 A;  2ZYZ B;  4DA2 A;  2WCW A;  4EV1 A;  2FKC A;  3AJV B;  3IF0 X;  3P1Z A;  1UWV A;  2BH2 A;  3BT7 A;  2DBS A;  4TKK A;  4G6V A;  1OB9 A;  3DNX A;  3P1Z B;  4ZQU A;  1R0V A;  4E6Z A;  2GJW A;  1R11 A;  4DAP A;  2INB A;  1GEF A;  4QBL A;  2WIW A;  2W8M A;  1IPI A;  2WJ0 A;  2JJQ A;  2CZR A;  2IXS A;  2Z0R A;  1Y88 A;  2FCO A;  2OST A;  1RLV A;  2FKH B;  2WCZ A;  2EO0 A;  1YNM A;  3P1Y A; 
#chains in the Genus database with same CATH homology
 4TKD A;  4QBO A;  2OKF A;  1XMX A;  1F1Z A;  1HH1 A;  1T0F A;  2VLD A;  2CV8 A;  2VS1 A;  3FOV A;  3IEY A;  5FDK A;  2WIZ A;  2FLC A;  4LQE A;  2FL3 A;  3IEY B;  1A79 A;  2ZYZ A;  4QBN A;  1Y1O A;  2GW6 A;  4G6U A;  4DAV A;  3AJV A;  1ZP7 A;  1RZN A;  1OB8 A;  2ZYZ B;  4DA2 A;  2WCW A;  4EV1 A;  2FKC A;  3AJV B;  3IF0 X;  3P1Z A;  1UWV A;  2BH2 A;  3BT7 A;  2DBS A;  4TKK A;  4G6V A;  1OB9 A;  3DNX A;  3P1Z B;  4ZQU A;  1R0V A;  4E6Z A;  2GJW A;  1R11 A;  4DAP A;  2INB A;  1GEF A;  4QBL A;  2WIW A;  2W8M A;  1IPI A;  2WJ0 A;  2JJQ A;  2CZR A;  2IXS A;  2Z0R A;  1Y88 A;  2FCO A;  2OST A;  1RLV A;  2FKH B;  2WCZ A;  2EO0 A;  1YNM A;  3P1Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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