2QOJZ

Coevolution of a homing endonuclease and its host target sequence
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
254
structure length
254
Chain Sequence
GSDLTYAYLVGLFEGDGYFSITKKGKYLTYELGIELSIKDVQLIYKIKKILGIGIVSFRKRNEIEMVALRIRDKNHLKSFILPIFEKYPMFSNKQYDYLRFRNALLSGIISLEDLPDYTRSDEPLNSIESIINTSYFSAWLVGFIEAEGCFSVYKLNKDDDYLIASFDIAQRDGDILISAIRKYLSFTTKVYLDKTNCSKLKVTSVRSVENIIKFLQNAPVKLLGNKKLQYLLWLKQLRKISRYSEKIKIPSNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
source organism Emericella nidulans
publication title Coevolution of a homing endonuclease and its host target sequence.
pubmed doi rcsb
molecule keywords Intron-encoded DNA endonuclease I-AniI
total genus 68
structure length 254
sequence length 254
ec nomenclature ec 3.1.-.-:
pdb deposition date 2007-07-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
Z PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2qojZ01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2qojZ02
1MOWA 2XE0B 3C0XA 4UN9A 2VBJA 2VBOA 4AAFA 1N3EA 3MXAA 4UNBA 1DQ3A 1DFAA 3R7PA 4D6OA 5E5SA 1BP7A 2XE0A 4D6NA 4YISA 2VBLB 1VDEA 5A0WA 4AQUA 4UN7G 4UNCA 1B24A 3MIPA 1EF0A 2VS7A 4Z20A 1LWSA 3EH8A 3HYJA 4AAGA 3OORA 4AAEA 4UT0A 3E54A 3QQYA 5E5OA 3MX9A 4UN7A 5A72A 1T9JA 3MXBB 4EFJA 2DCHX 5A0MB 1P8KZ 3UVFA 2I3PA 4LQ0A 2VBNB 4AQXA 4AADA 1G9ZA 2EX5A 2VBLA 1AF5A 5AK9A 1JVAA 4UN8G 4AABA 5A77A 4Z1ZA 2QOJZ 5AKFA 5E67A 4UN8A 1R7MA 3MXBA 2VS8A 2AB5A 3KO2A 4YITA 5A78A 5A0MA 5E63A 2CW8A 1N3FA 4YHXA 2VBNA 2VBJB 1U0CA 2VBOB 3HYIA 2FLDA 4Z1XA 3MISA 4LOXA 1U0DA 1LWTA 1T9IA 1M5XA 3C0WA 5AKNA 4UNAA 4UN9G 1G9YA 2O7MA 5A74A 2CW7A 3FD2A 1UM2A 5AKMA 2I3QA 3OOLA
chains in the Genus database with same CATH superfamily
1MOWA 2XE0B 3C0XA 4UN9A 2VBJA 2VBOA 4AAFA 1N3EA 3MXAA 4UNBA 1DQ3A 1DFAA 3R7PA 4D6OA 4KZSA 5E5SA 1BP7A 2XE0A 4D6NA 4YISA 2VBLB 1VDEA 5A0WA 4AQUA 4UN7G 4UNCA 1B24A 3MIPA 1EF0A 2VS7A 4Z20A 1LWSA 3EH8A 3HYJA 4AAGA 3OORA 4AAEA 4UT0A 3E54A 3QQYA 5E5OA 3MX9A 4UN7A 5A72A 1T9JA 3MXBB 4EFJA 2DCHX 5A0MB 1P8KZ 3UVFA 2I3PA 4LQ0A 2VBNB 4AQXA 4AADA 1G9ZA 2EX5A 2VBLA 2F4LA 1AF5A 5AK9A 1JVAA 4UN8G 4AABA 5A77A 4Z1ZA 2QOJZ 5AKFA 5E67A 4UN8A 1R7MA 3MXBA 2VS8A 2AB5A 3KO2A 4YITA 5A78A 5A0MA 5E63A 2CW8A 1N3FA 4YHXA 2VBNA 2VBJB 1U0CA 2VBOB 3HYIA 2FLDA 4Z1XA 3MISA 4LOXA 1U0DA 1LWTA 1T9IA 1M5XA 3C0WA 5AKNA 4UNAA 4UN9G 1G9YA 2O7MA 5A74A 2CW7A 3FD2A 1UM2A 5AKMA 2I3QA 3OOLA
chains in the Genus database with same CATH topology
1MOWA 2XE0B 3C0XA 4UN9A 2VBJA 2VBOA 4AAFA 1N3EA 3MXAA 4UNBA 1DQ3A 1DFAA 3R7PA 4D6OA 5E5SA 1BP7A 2XE0A 4D6NA 4YISA 2VBLB 1VDEA 5A0WA 4AQUA 4UN7G 4UNCA 1B24A 3MIPA 1EF0A 2VS7A 4Z20A 1LWSA 3EH8A 3HYJA 4AAGA 3OORA 4AAEA 4UT0A 3E54A 3QQYA 5E5OA 3MX9A 4UN7A 5A72A 1T9JA 3MXBB 4EFJA 2DCHX 5A0MB 1P8KZ 3UVFA 2I3PA 4LQ0A 2VBNB 4AQXA 4AADA 1G9ZA 2EX5A 2VBLA 1AF5A 5AK9A 1JVAA 4UN8G 4AABA 5A77A 4Z1ZA 2QOJZ 5AKFA 5E67A 4UN8A 1R7MA 3MXBA 2VS8A 2AB5A 3KO2A 4YITA 5A78A 5A0MA 5E63A 2CW8A 1N3FA 4YHXA 2VBNA 2VBJB 1U0CA 2VBOB 3HYIA 2FLDA 4Z1XA 3MISA 4LOXA 1U0DA 1LWTA 1T9IA 1M5XA 3C0WA 5AKNA 4UNAA 4UN9G 1G9YA 2O7MA 5A74A 2CW7A 3FD2A 1UM2A 5AKMA 2I3QA 3OOLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MOW A;  2XE0 B;  3C0X A;  4UN9 A;  2VBJ A;  2VBO A;  4AAF A;  1N3E A;  3MXA A;  4UNB A;  1DQ3 A;  1DFA A;  3R7P A;  4D6O A;  5E5S A;  1BP7 A;  2XE0 A;  4D6N A;  4YIS A;  2VBL B;  1VDE A;  5A0W A;  4AQU A;  4UN7 G;  4UNC A;  1B24 A;  3MIP A;  1EF0 A;  2VS7 A;  4Z20 A;  1LWS A;  3EH8 A;  3HYJ A;  4AAG A;  3OOR A;  4AAE A;  4UT0 A;  3E54 A;  3QQY A;  5E5O A;  3MX9 A;  4UN7 A;  5A72 A;  1T9J A;  3MXB B;  4EFJ A;  2DCH X;  5A0M B;  1P8K Z;  3UVF A;  2I3P A;  4LQ0 A;  2VBN B;  4AQX A;  4AAD A;  1G9Z A;  2EX5 A;  2VBL A;  1AF5 A;  5AK9 A;  1JVA A;  4UN8 G;  4AAB A;  5A77 A;  4Z1Z A;  2QOJ Z;  5AKF A;  5E67 A;  4UN8 A;  1R7M A;  3MXB A;  2VS8 A;  2AB5 A;  3KO2 A;  4YIT A;  5A78 A;  5A0M A;  5E63 A;  2CW8 A;  1N3F A;  4YHX A;  2VBN A;  2VBJ B;  1U0C A;  2VBO B;  3HYI A;  2FLD A;  4Z1X A;  3MIS A;  4LOX A;  1U0D A;  1LWT A;  1T9I A;  1M5X A;  3C0W A;  5AKN A;  4UNA A;  4UN9 G;  1G9Y A;  2O7M A;  5A74 A;  2CW7 A;  3FD2 A;  1UM2 A;  5AKM A;  2I3Q A;  3OOL A; 
#chains in the Genus database with same CATH topology
 1MOW A;  2XE0 B;  3C0X A;  4UN9 A;  2VBJ A;  2VBO A;  4AAF A;  1N3E A;  3MXA A;  4UNB A;  1DQ3 A;  1DFA A;  3R7P A;  4D6O A;  4KZS A;  5E5S A;  1BP7 A;  2XE0 A;  4D6N A;  4YIS A;  2VBL B;  1VDE A;  5A0W A;  4AQU A;  4UN7 G;  4UNC A;  1B24 A;  3MIP A;  1EF0 A;  2VS7 A;  4Z20 A;  1LWS A;  3EH8 A;  3HYJ A;  4AAG A;  3OOR A;  4AAE A;  4UT0 A;  3E54 A;  3QQY A;  5E5O A;  3MX9 A;  4UN7 A;  5A72 A;  1T9J A;  3MXB B;  4EFJ A;  2DCH X;  5A0M B;  1P8K Z;  3UVF A;  2I3P A;  4LQ0 A;  2VBN B;  4AQX A;  4AAD A;  1G9Z A;  2EX5 A;  2VBL A;  2F4L A;  1AF5 A;  5AK9 A;  1JVA A;  4UN8 G;  4AAB A;  5A77 A;  4Z1Z A;  2QOJ Z;  5AKF A;  5E67 A;  4UN8 A;  1R7M A;  3MXB A;  2VS8 A;  2AB5 A;  3KO2 A;  4YIT A;  5A78 A;  5A0M A;  5E63 A;  2CW8 A;  1N3F A;  4YHX A;  2VBN A;  2VBJ B;  1U0C A;  2VBO B;  3HYI A;  2FLD A;  4Z1X A;  3MIS A;  4LOX A;  1U0D A;  1LWT A;  1T9I A;  1M5X A;  3C0W A;  5AKN A;  4UNA A;  4UN9 G;  1G9Y A;  2O7M A;  5A74 A;  2CW7 A;  3FD2 A;  1UM2 A;  5AKM A;  2I3Q A;  3OOL A; 
#chains in the Genus database with same CATH homology
 1MOW A;  2XE0 B;  3C0X A;  4UN9 A;  2VBJ A;  2VBO A;  4AAF A;  1N3E A;  3MXA A;  4UNB A;  1DQ3 A;  1DFA A;  3R7P A;  4D6O A;  5E5S A;  1BP7 A;  2XE0 A;  4D6N A;  4YIS A;  2VBL B;  1VDE A;  5A0W A;  4AQU A;  4UN7 G;  4UNC A;  1B24 A;  3MIP A;  1EF0 A;  2VS7 A;  4Z20 A;  1LWS A;  3EH8 A;  3HYJ A;  4AAG A;  3OOR A;  4AAE A;  4UT0 A;  3E54 A;  3QQY A;  5E5O A;  3MX9 A;  4UN7 A;  5A72 A;  1T9J A;  3MXB B;  4EFJ A;  2DCH X;  5A0M B;  1P8K Z;  3UVF A;  2I3P A;  4LQ0 A;  2VBN B;  4AQX A;  4AAD A;  1G9Z A;  2EX5 A;  2VBL A;  1AF5 A;  5AK9 A;  1JVA A;  4UN8 G;  4AAB A;  5A77 A;  4Z1Z A;  2QOJ Z;  5AKF A;  5E67 A;  4UN8 A;  1R7M A;  3MXB A;  2VS8 A;  2AB5 A;  3KO2 A;  4YIT A;  5A78 A;  5A0M A;  5E63 A;  2CW8 A;  1N3F A;  4YHX A;  2VBN A;  2VBJ B;  1U0C A;  2VBO B;  3HYI A;  2FLD A;  4Z1X A;  3MIS A;  4LOX A;  1U0D A;  1LWT A;  1T9I A;  1M5X A;  3C0W A;  5AKN A;  4UNA A;  4UN9 G;  1G9Y A;  2O7M A;  5A74 A;  2CW7 A;  3FD2 A;  1UM2 A;  5AKM A;  2I3Q A;  3OOL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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