2VBJA

Molecular basis of human xpc gene recognition and cleavage by engineered homing endonuclease heterodimers
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIEPNQSYKFKHRLKLTFKVTQKTQRRWFLDKLVDEIGVGYVRDEGSVSNYILSEIKPLRNFLTQLQPFLKLKQKQANLVLKITEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 48
structure length 152
sequence length 152
ec nomenclature ec 3.1.-.-:
pdb deposition date 2007-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2vbjA00
2CW7A 4UN9A 1DQ3A 4Z1ZA 2VBLA 4YISA 3HYJA 5A78A 2QOJZ 4Z1XA 2FLDA 4UNBA 1N3EA 4UN7G 1VDEA 1N3FA 4UN8A 3MX9A 5E63A 3FD2A 2VBLB 3UVFA 4EFJA 4AQUA 2I3QA 1R7MA 1U0DA 1B24A 1P8KZ 4D6OA 1UM2A 3E54A 5AKMA 4UT0A 5E5SA 3MIPA 2VBOA 2XE0A 5A0MA 4AAEA 4D6NA 3EH8A 2VS7A 1T9JA 3C0XA 2VBNA 1AF5A 5AK9A 4AABA 5AKNA 4UN7A 5E5OA 1DFAA 5A72A 2O7MA 2VBOB 4AQXA 4YITA 2XE0B 4YHXA 4UNAA 5A0MB 3MXBA 4UN9G 3OORA 2I3PA 3R7PA 1JVAA 4UNCA 2VBJA 4Z20A 3HYIA 1BP7A 2EX5A 2CW8A 5A74A 2VBNB 1T9IA 1EF0A 5A77A 1U0CA 1LWTA 3QQYA 1M5XA 2AB5A 3OOLA 3MXAA 4LQ0A 5A0WA 3MXBB 4UN8G 4LOXA 3KO2A 5AKFA 3MISA 4AAFA 2VBJB 2DCHX 1G9YA 2VS8A 4AADA 1G9ZA 1MOWA 4AAGA 1LWSA 5E67A 3C0WA
chains in the Genus database with same CATH superfamily
2CW7A 4UN9A 1DQ3A 4Z1ZA 2VBLA 3HYJA 4YISA 5A78A 2QOJZ 4Z1XA 2FLDA 4UNBA 1N3EA 4UN7G 1VDEA 1N3FA 4UN8A 3MX9A 4KZSA 5E63A 3FD2A 2VBLB 3UVFA 4EFJA 4AQUA 2I3QA 1R7MA 1U0DA 1B24A 1P8KZ 4D6OA 1UM2A 3E54A 2F4LA 5AKMA 4UT0A 5E5SA 3MIPA 2VBOA 2XE0A 5A0MA 4AAEA 4D6NA 3EH8A 2VS7A 1T9JA 3C0XA 2VBNA 1AF5A 5AK9A 4AABA 5AKNA 4UN7A 5E5OA 1DFAA 5A72A 2O7MA 2VBOB 4AQXA 4YITA 2XE0B 4YHXA 4UNAA 5A0MB 3MXBA 4UN9G 3OORA 2I3PA 3R7PA 1JVAA 4UNCA 2VBJA 4Z20A 3HYIA 1BP7A 2EX5A 2CW8A 5A74A 2VBNB 1T9IA 1EF0A 5A77A 1U0CA 1LWTA 3QQYA 1M5XA 2AB5A 3OOLA 3MXAA 4LQ0A 5A0WA 3MXBB 4UN8G 4LOXA 3KO2A 5AKFA 3MISA 4AAFA 2VBJB 2DCHX 1G9YA 2VS8A 4AADA 1G9ZA 1MOWA 4AAGA 1LWSA 5E67A 3C0WA
chains in the Genus database with same CATH topology
2CW7A 4UN9A 1DQ3A 4Z1ZA 2VBLA 4YISA 3HYJA 5A78A 2QOJZ 4Z1XA 2FLDA 4UNBA 1N3EA 4UN7G 1VDEA 1N3FA 4UN8A 3MX9A 5E63A 3FD2A 2VBLB 3UVFA 4EFJA 4AQUA 2I3QA 1R7MA 1U0DA 1B24A 1P8KZ 4D6OA 1UM2A 3E54A 5AKMA 4UT0A 5E5SA 3MIPA 2VBOA 2XE0A 5A0MA 4AAEA 4D6NA 3EH8A 2VS7A 1T9JA 3C0XA 2VBNA 1AF5A 5AK9A 4AABA 5AKNA 4UN7A 5E5OA 1DFAA 5A72A 2O7MA 2VBOB 4AQXA 4YITA 2XE0B 4YHXA 4UNAA 5A0MB 3MXBA 4UN9G 3OORA 2I3PA 3R7PA 1JVAA 4UNCA 2VBJA 4Z20A 3HYIA 1BP7A 2EX5A 2CW8A 5A74A 2VBNB 1T9IA 1EF0A 5A77A 1U0CA 1LWTA 3QQYA 1M5XA 2AB5A 3OOLA 3MXAA 4LQ0A 5A0WA 3MXBB 4UN8G 4LOXA 3KO2A 5AKFA 3MISA 4AAFA 2VBJB 2DCHX 1G9YA 2VS8A 4AADA 1G9ZA 1MOWA 4AAGA 1LWSA 5E67A 3C0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CW7 A;  4UN9 A;  1DQ3 A;  4Z1Z A;  2VBL A;  4YIS A;  3HYJ A;  5A78 A;  2QOJ Z;  4Z1X A;  2FLD A;  4UNB A;  1N3E A;  4UN7 G;  1VDE A;  1N3F A;  4UN8 A;  3MX9 A;  5E63 A;  3FD2 A;  2VBL B;  3UVF A;  4EFJ A;  4AQU A;  2I3Q A;  1R7M A;  1U0D A;  1B24 A;  1P8K Z;  4D6O A;  1UM2 A;  3E54 A;  5AKM A;  4UT0 A;  5E5S A;  3MIP A;  2VBO A;  2XE0 A;  5A0M A;  4AAE A;  4D6N A;  3EH8 A;  2VS7 A;  1T9J A;  3C0X A;  2VBN A;  1AF5 A;  5AK9 A;  4AAB A;  5AKN A;  4UN7 A;  5E5O A;  1DFA A;  5A72 A;  2O7M A;  2VBO B;  4AQX A;  4YIT A;  2XE0 B;  4YHX A;  4UNA A;  5A0M B;  3MXB A;  4UN9 G;  3OOR A;  2I3P A;  3R7P A;  1JVA A;  4UNC A;  2VBJ A;  4Z20 A;  3HYI A;  1BP7 A;  2EX5 A;  2CW8 A;  5A74 A;  2VBN B;  1T9I A;  1EF0 A;  5A77 A;  1U0C A;  1LWT A;  3QQY A;  1M5X A;  2AB5 A;  3OOL A;  3MXA A;  4LQ0 A;  5A0W A;  3MXB B;  4UN8 G;  4LOX A;  3KO2 A;  5AKF A;  3MIS A;  4AAF A;  2VBJ B;  2DCH X;  1G9Y A;  2VS8 A;  4AAD A;  1G9Z A;  1MOW A;  4AAG A;  1LWS A;  5E67 A;  3C0W A; 
#chains in the Genus database with same CATH topology
 2CW7 A;  4UN9 A;  1DQ3 A;  4Z1Z A;  2VBL A;  3HYJ A;  4YIS A;  5A78 A;  2QOJ Z;  4Z1X A;  2FLD A;  4UNB A;  1N3E A;  4UN7 G;  1VDE A;  1N3F A;  4UN8 A;  3MX9 A;  4KZS A;  5E63 A;  3FD2 A;  2VBL B;  3UVF A;  4EFJ A;  4AQU A;  2I3Q A;  1R7M A;  1U0D A;  1B24 A;  1P8K Z;  4D6O A;  1UM2 A;  3E54 A;  2F4L A;  5AKM A;  4UT0 A;  5E5S A;  3MIP A;  2VBO A;  2XE0 A;  5A0M A;  4AAE A;  4D6N A;  3EH8 A;  2VS7 A;  1T9J A;  3C0X A;  2VBN A;  1AF5 A;  5AK9 A;  4AAB A;  5AKN A;  4UN7 A;  5E5O A;  1DFA A;  5A72 A;  2O7M A;  2VBO B;  4AQX A;  4YIT A;  2XE0 B;  4YHX A;  4UNA A;  5A0M B;  3MXB A;  4UN9 G;  3OOR A;  2I3P A;  3R7P A;  1JVA A;  4UNC A;  2VBJ A;  4Z20 A;  3HYI A;  1BP7 A;  2EX5 A;  2CW8 A;  5A74 A;  2VBN B;  1T9I A;  1EF0 A;  5A77 A;  1U0C A;  1LWT A;  3QQY A;  1M5X A;  2AB5 A;  3OOL A;  3MXA A;  4LQ0 A;  5A0W A;  3MXB B;  4UN8 G;  4LOX A;  3KO2 A;  5AKF A;  3MIS A;  4AAF A;  2VBJ B;  2DCH X;  1G9Y A;  2VS8 A;  4AAD A;  1G9Z A;  1MOW A;  4AAG A;  1LWS A;  5E67 A;  3C0W A; 
#chains in the Genus database with same CATH homology
 2CW7 A;  4UN9 A;  1DQ3 A;  4Z1Z A;  2VBL A;  4YIS A;  3HYJ A;  5A78 A;  2QOJ Z;  4Z1X A;  2FLD A;  4UNB A;  1N3E A;  4UN7 G;  1VDE A;  1N3F A;  4UN8 A;  3MX9 A;  5E63 A;  3FD2 A;  2VBL B;  3UVF A;  4EFJ A;  4AQU A;  2I3Q A;  1R7M A;  1U0D A;  1B24 A;  1P8K Z;  4D6O A;  1UM2 A;  3E54 A;  5AKM A;  4UT0 A;  5E5S A;  3MIP A;  2VBO A;  2XE0 A;  5A0M A;  4AAE A;  4D6N A;  3EH8 A;  2VS7 A;  1T9J A;  3C0X A;  2VBN A;  1AF5 A;  5AK9 A;  4AAB A;  5AKN A;  4UN7 A;  5E5O A;  1DFA A;  5A72 A;  2O7M A;  2VBO B;  4AQX A;  4YIT A;  2XE0 B;  4YHX A;  4UNA A;  5A0M B;  3MXB A;  4UN9 G;  3OOR A;  2I3P A;  3R7P A;  1JVA A;  4UNC A;  2VBJ A;  4Z20 A;  3HYI A;  1BP7 A;  2EX5 A;  2CW8 A;  5A74 A;  2VBN B;  1T9I A;  1EF0 A;  5A77 A;  1U0C A;  1LWT A;  3QQY A;  1M5X A;  2AB5 A;  3OOL A;  3MXA A;  4LQ0 A;  5A0W A;  3MXB B;  4UN8 G;  4LOX A;  3KO2 A;  5AKF A;  3MIS A;  4AAF A;  2VBJ B;  2DCH X;  1G9Y A;  2VS8 A;  4AAD A;  1G9Z A;  1MOW A;  4AAG A;  1LWS A;  5E67 A;  3C0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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