2VBJB

Molecular basis of human xpc gene recognition and cleavage by engineered homing endonuclease heterodimers
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDADGSIIAQIEPNQSSKFKHRLKLTFQVTQKTQRRWFLDKLVDEIGVGYVRDSGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 48
structure length 152
sequence length 152
ec nomenclature ec 3.1.-.-:
pdb deposition date 2007-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2vbjB00
3KO2A 2QOJZ 2VBJA 3MXBB 4UNCA 5A0MA 1N3EA 3HYJA 2FLDA 3MXBA 4Z20A 3C0WA 2I3PA 1EF0A 5AKMA 4Z1XA 4AABA 4UNBA 4UT0A 4LOXA 2EX5A 3EH8A 1G9ZA 1LWTA 5AKNA 3HYIA 3QQYA 2VS7A 2VBOB 3UVFA 5A77A 5A72A 3E54A 3R7PA 4LQ0A 2VBNB 4UNAA 4YISA 5AKFA 3OOLA 2CW8A 4YHXA 2VBOA 4AQXA 1MOWA 2VBNA 3MX9A 3FD2A 1P8KZ 2I3QA 4Z1ZA 4AADA 1UM2A 4D6OA 2AB5A 1B24A 3C0XA 4AAEA 4UN7A 1M5XA 1T9JA 2VBLB 2XE0B 1U0CA 4EFJA 4UN7G 5E5SA 1G9YA 2DCHX 5A74A 1N3FA 3MISA 2VBLA 2XE0A 5E63A 5A0WA 1AF5A 4UN8A 1LWSA 1DQ3A 3MIPA 4UN9A 1JVAA 2O7MA 4AAGA 2CW7A 5E5OA 1BP7A 4UN8G 4YITA 4AAFA 3OORA 1R7MA 1DFAA 5AK9A 4UN9G 5E67A 5A78A 1T9IA 4AQUA 2VS8A 1U0DA 2VBJB 1VDEA 5A0MB 4D6NA 3MXAA
chains in the Genus database with same CATH superfamily
3KO2A 2QOJZ 2VBJA 3MXBB 4UNCA 5A0MA 1N3EA 3HYJA 2FLDA 3MXBA 4Z20A 3C0WA 2I3PA 1EF0A 5AKMA 4Z1XA 4AABA 4UNBA 4UT0A 4LOXA 2EX5A 2F4LA 3EH8A 1G9ZA 1LWTA 5AKNA 3HYIA 3QQYA 2VS7A 2VBOB 3UVFA 5A77A 5A72A 3E54A 3R7PA 4LQ0A 2VBNB 4UNAA 4YISA 5AKFA 3OOLA 2CW8A 4YHXA 2VBOA 4AQXA 1MOWA 2VBNA 3MX9A 3FD2A 1P8KZ 2I3QA 4Z1ZA 4AADA 1UM2A 4D6OA 2AB5A 1B24A 3C0XA 4AAEA 4KZSA 4UN7A 1M5XA 1T9JA 2VBLB 2XE0B 1U0CA 4EFJA 4UN7G 5E5SA 1G9YA 2DCHX 5A74A 1N3FA 3MISA 2VBLA 2XE0A 5E63A 5A0WA 1AF5A 4UN8A 1LWSA 1DQ3A 3MIPA 4UN9A 1JVAA 2O7MA 4AAGA 2CW7A 5E5OA 1BP7A 4UN8G 4YITA 4AAFA 3OORA 1R7MA 1DFAA 5AK9A 4UN9G 5E67A 5A78A 1T9IA 4AQUA 2VS8A 1U0DA 2VBJB 1VDEA 5A0MB 4D6NA 3MXAA
chains in the Genus database with same CATH topology
3KO2A 2QOJZ 2VBJA 3MXBB 4UNCA 5A0MA 1N3EA 3HYJA 2FLDA 3MXBA 4Z20A 3C0WA 2I3PA 1EF0A 5AKMA 4Z1XA 4AABA 4UNBA 4UT0A 4LOXA 2EX5A 3EH8A 1G9ZA 1LWTA 5AKNA 3HYIA 3QQYA 2VS7A 2VBOB 3UVFA 5A77A 5A72A 3E54A 3R7PA 4LQ0A 2VBNB 4UNAA 4YISA 5AKFA 3OOLA 2CW8A 4YHXA 2VBOA 4AQXA 1MOWA 2VBNA 3MX9A 3FD2A 1P8KZ 2I3QA 4Z1ZA 4AADA 1UM2A 4D6OA 2AB5A 1B24A 3C0XA 4AAEA 4UN7A 1M5XA 1T9JA 2VBLB 2XE0B 1U0CA 4EFJA 4UN7G 5E5SA 1G9YA 2DCHX 5A74A 1N3FA 3MISA 2VBLA 2XE0A 5E63A 5A0WA 1AF5A 4UN8A 1LWSA 1DQ3A 3MIPA 4UN9A 1JVAA 2O7MA 4AAGA 2CW7A 5E5OA 1BP7A 4UN8G 4YITA 4AAFA 3OORA 1R7MA 1DFAA 5AK9A 4UN9G 5E67A 5A78A 1T9IA 4AQUA 2VS8A 1U0DA 2VBJB 1VDEA 5A0MB 4D6NA 3MXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KO2 A;  2QOJ Z;  2VBJ A;  3MXB B;  4UNC A;  5A0M A;  1N3E A;  3HYJ A;  2FLD A;  3MXB A;  4Z20 A;  3C0W A;  2I3P A;  1EF0 A;  5AKM A;  4Z1X A;  4AAB A;  4UNB A;  4UT0 A;  4LOX A;  2EX5 A;  3EH8 A;  1G9Z A;  1LWT A;  5AKN A;  3HYI A;  3QQY A;  2VS7 A;  2VBO B;  3UVF A;  5A77 A;  5A72 A;  3E54 A;  3R7P A;  4LQ0 A;  2VBN B;  4UNA A;  4YIS A;  5AKF A;  3OOL A;  2CW8 A;  4YHX A;  2VBO A;  4AQX A;  1MOW A;  2VBN A;  3MX9 A;  3FD2 A;  1P8K Z;  2I3Q A;  4Z1Z A;  4AAD A;  1UM2 A;  4D6O A;  2AB5 A;  1B24 A;  3C0X A;  4AAE A;  4UN7 A;  1M5X A;  1T9J A;  2VBL B;  2XE0 B;  1U0C A;  4EFJ A;  4UN7 G;  5E5S A;  1G9Y A;  2DCH X;  5A74 A;  1N3F A;  3MIS A;  2VBL A;  2XE0 A;  5E63 A;  5A0W A;  1AF5 A;  4UN8 A;  1LWS A;  1DQ3 A;  3MIP A;  4UN9 A;  1JVA A;  2O7M A;  4AAG A;  2CW7 A;  5E5O A;  1BP7 A;  4UN8 G;  4YIT A;  4AAF A;  3OOR A;  1R7M A;  1DFA A;  5AK9 A;  4UN9 G;  5E67 A;  5A78 A;  1T9I A;  4AQU A;  2VS8 A;  1U0D A;  2VBJ B;  1VDE A;  5A0M B;  4D6N A;  3MXA A; 
#chains in the Genus database with same CATH topology
 3KO2 A;  2QOJ Z;  2VBJ A;  3MXB B;  4UNC A;  5A0M A;  1N3E A;  3HYJ A;  2FLD A;  3MXB A;  4Z20 A;  3C0W A;  2I3P A;  1EF0 A;  5AKM A;  4Z1X A;  4AAB A;  4UNB A;  4UT0 A;  4LOX A;  2EX5 A;  2F4L A;  3EH8 A;  1G9Z A;  1LWT A;  5AKN A;  3HYI A;  3QQY A;  2VS7 A;  2VBO B;  3UVF A;  5A77 A;  5A72 A;  3E54 A;  3R7P A;  4LQ0 A;  2VBN B;  4UNA A;  4YIS A;  5AKF A;  3OOL A;  2CW8 A;  4YHX A;  2VBO A;  4AQX A;  1MOW A;  2VBN A;  3MX9 A;  3FD2 A;  1P8K Z;  2I3Q A;  4Z1Z A;  4AAD A;  1UM2 A;  4D6O A;  2AB5 A;  1B24 A;  3C0X A;  4AAE A;  4KZS A;  4UN7 A;  1M5X A;  1T9J A;  2VBL B;  2XE0 B;  1U0C A;  4EFJ A;  4UN7 G;  5E5S A;  1G9Y A;  2DCH X;  5A74 A;  1N3F A;  3MIS A;  2VBL A;  2XE0 A;  5E63 A;  5A0W A;  1AF5 A;  4UN8 A;  1LWS A;  1DQ3 A;  3MIP A;  4UN9 A;  1JVA A;  2O7M A;  4AAG A;  2CW7 A;  5E5O A;  1BP7 A;  4UN8 G;  4YIT A;  4AAF A;  3OOR A;  1R7M A;  1DFA A;  5AK9 A;  4UN9 G;  5E67 A;  5A78 A;  1T9I A;  4AQU A;  2VS8 A;  1U0D A;  2VBJ B;  1VDE A;  5A0M B;  4D6N A;  3MXA A; 
#chains in the Genus database with same CATH homology
 3KO2 A;  2QOJ Z;  2VBJ A;  3MXB B;  4UNC A;  5A0M A;  1N3E A;  3HYJ A;  2FLD A;  3MXB A;  4Z20 A;  3C0W A;  2I3P A;  1EF0 A;  5AKM A;  4Z1X A;  4AAB A;  4UNB A;  4UT0 A;  4LOX A;  2EX5 A;  3EH8 A;  1G9Z A;  1LWT A;  5AKN A;  3HYI A;  3QQY A;  2VS7 A;  2VBO B;  3UVF A;  5A77 A;  5A72 A;  3E54 A;  3R7P A;  4LQ0 A;  2VBN B;  4UNA A;  4YIS A;  5AKF A;  3OOL A;  2CW8 A;  4YHX A;  2VBO A;  4AQX A;  1MOW A;  2VBN A;  3MX9 A;  3FD2 A;  1P8K Z;  2I3Q A;  4Z1Z A;  4AAD A;  1UM2 A;  4D6O A;  2AB5 A;  1B24 A;  3C0X A;  4AAE A;  4UN7 A;  1M5X A;  1T9J A;  2VBL B;  2XE0 B;  1U0C A;  4EFJ A;  4UN7 G;  5E5S A;  1G9Y A;  2DCH X;  5A74 A;  1N3F A;  3MIS A;  2VBL A;  2XE0 A;  5E63 A;  5A0W A;  1AF5 A;  4UN8 A;  1LWS A;  1DQ3 A;  3MIP A;  4UN9 A;  1JVA A;  2O7M A;  4AAG A;  2CW7 A;  5E5O A;  1BP7 A;  4UN8 G;  4YIT A;  4AAF A;  3OOR A;  1R7M A;  1DFA A;  5AK9 A;  4UN9 G;  5E67 A;  5A78 A;  1T9I A;  4AQU A;  2VS8 A;  1U0D A;  2VBJ B;  1VDE A;  5A0M B;  4D6N A;  3MXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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