2VBNB

Molecular basis of human xpc gene recognition and cleavage by engineered homing endonuclease heterodimers
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIEPNQSYKFKHRLKLTFKVTQKTQRRWFLDKLVDEIGVGYVSDSGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
pubmed doi rcsb
molecule tags Hydrolase
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 48
structure length 152
sequence length 152
ec nomenclature ec 3.1.-.-:
pdb deposition date 2007-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2vbnB00
1EF0A 3R7PA 3MXBA 2XE0B 1AF5A 3QQYA 4UN9G 4UNAA 4LQ0A 2EX5A 2VS7A 3MXAA 2VBJA 4AQXA 4LOXA 2VBOB 5E67A 4YITA 4Z1ZA 2O7MA 4UNBA 4AQUA 5E5OA 1U0CA 1G9ZA 4UN8G 1P8KZ 5E63A 4UNCA 1G9YA 3HYJA 1M5XA 4AABA 2VBNA 1BP7A 1UM2A 2I3QA 4AADA 5AKFA 2CW7A 2CW8A 4UN7A 4YISA 3C0XA 2DCHX 1B24A 4D6NA 5AKNA 4AAEA 5A0MB 3HYIA 4AAGA 3MX9A 1DQ3A 1VDEA 4D6OA 2XE0A 2VBLB 1U0DA 4UN9A 3OORA 5E5SA 4YHXA 3EH8A 1JVAA 3MISA 1N3FA 5AKMA 4UT0A 2VBOA 3MXBB 1LWTA 2I3PA 2VS8A 4EFJA 4AAFA 5AK9A 1T9JA 5A77A 2VBJB 5A74A 3FD2A 3UVFA 3C0WA 3MIPA 3OOLA 3KO2A 2QOJZ 5A72A 1N3EA 5A0MA 2AB5A 3E54A 5A0WA 4Z1XA 1DFAA 1T9IA 2VBNB 1R7MA 4UN8A 2VBLA 1MOWA 2FLDA 5A78A 1LWSA 4Z20A 4UN7G
chains in the Genus database with same CATH superfamily
1EF0A 3R7PA 3MXBA 2XE0B 1AF5A 3QQYA 4UN9G 4UNAA 4LQ0A 2EX5A 2VS7A 3MXAA 2VBJA 4AQXA 4LOXA 2VBOB 5E67A 4YITA 4Z1ZA 2O7MA 4UNBA 4AQUA 5E5OA 1U0CA 1G9ZA 4UN8G 1P8KZ 5E63A 4UNCA 1G9YA 3HYJA 1M5XA 4AABA 2VBNA 1BP7A 1UM2A 2I3QA 4KZSA 4AADA 5AKFA 2CW7A 2CW8A 4UN7A 2F4LA 4YISA 3C0XA 2DCHX 1B24A 4D6NA 5AKNA 4AAEA 5A0MB 3HYIA 4AAGA 3MX9A 1DQ3A 1VDEA 4D6OA 2XE0A 2VBLB 1U0DA 4UN9A 3OORA 5E5SA 4YHXA 3EH8A 1JVAA 3MISA 1N3FA 5AKMA 4UT0A 2VBOA 3MXBB 1LWTA 2I3PA 2VS8A 4EFJA 4AAFA 5AK9A 1T9JA 5A77A 2VBJB 5A74A 3FD2A 3UVFA 3C0WA 3MIPA 3OOLA 3KO2A 2QOJZ 5A72A 1N3EA 5A0MA 2AB5A 3E54A 5A0WA 4Z1XA 1DFAA 1T9IA 2VBNB 1R7MA 4UN8A 2VBLA 1MOWA 2FLDA 5A78A 1LWSA 4Z20A 4UN7G
chains in the Genus database with same CATH topology
1EF0A 3R7PA 3MXBA 2XE0B 1AF5A 3QQYA 4UN9G 4UNAA 4LQ0A 2EX5A 2VS7A 3MXAA 2VBJA 4AQXA 4LOXA 2VBOB 5E67A 4YITA 4Z1ZA 2O7MA 4UNBA 4AQUA 5E5OA 1U0CA 1G9ZA 4UN8G 1P8KZ 5E63A 4UNCA 1G9YA 3HYJA 1M5XA 4AABA 2VBNA 1BP7A 1UM2A 2I3QA 4AADA 5AKFA 2CW7A 2CW8A 4UN7A 4YISA 3C0XA 2DCHX 1B24A 4D6NA 5AKNA 4AAEA 5A0MB 3HYIA 4AAGA 3MX9A 1DQ3A 1VDEA 4D6OA 2XE0A 2VBLB 1U0DA 4UN9A 3OORA 5E5SA 4YHXA 3EH8A 1JVAA 3MISA 1N3FA 5AKMA 4UT0A 2VBOA 3MXBB 1LWTA 2I3PA 2VS8A 4EFJA 4AAFA 5AK9A 1T9JA 5A77A 2VBJB 5A74A 3FD2A 3UVFA 3C0WA 3MIPA 3OOLA 3KO2A 2QOJZ 5A72A 1N3EA 5A0MA 2AB5A 3E54A 5A0WA 4Z1XA 1DFAA 1T9IA 2VBNB 1R7MA 4UN8A 2VBLA 1MOWA 2FLDA 5A78A 1LWSA 4Z20A 4UN7G
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EF0 A;  3R7P A;  3MXB A;  2XE0 B;  1AF5 A;  3QQY A;  4UN9 G;  4UNA A;  4LQ0 A;  2EX5 A;  2VS7 A;  3MXA A;  2VBJ A;  4AQX A;  4LOX A;  2VBO B;  5E67 A;  4YIT A;  4Z1Z A;  2O7M A;  4UNB A;  4AQU A;  5E5O A;  1U0C A;  1G9Z A;  4UN8 G;  1P8K Z;  5E63 A;  4UNC A;  1G9Y A;  3HYJ A;  1M5X A;  4AAB A;  2VBN A;  1BP7 A;  1UM2 A;  2I3Q A;  4AAD A;  5AKF A;  2CW7 A;  2CW8 A;  4UN7 A;  4YIS A;  3C0X A;  2DCH X;  1B24 A;  4D6N A;  5AKN A;  4AAE A;  5A0M B;  3HYI A;  4AAG A;  3MX9 A;  1DQ3 A;  1VDE A;  4D6O A;  2XE0 A;  2VBL B;  1U0D A;  4UN9 A;  3OOR A;  5E5S A;  4YHX A;  3EH8 A;  1JVA A;  3MIS A;  1N3F A;  5AKM A;  4UT0 A;  2VBO A;  3MXB B;  1LWT A;  2I3P A;  2VS8 A;  4EFJ A;  4AAF A;  5AK9 A;  1T9J A;  5A77 A;  2VBJ B;  5A74 A;  3FD2 A;  3UVF A;  3C0W A;  3MIP A;  3OOL A;  3KO2 A;  2QOJ Z;  5A72 A;  1N3E A;  5A0M A;  2AB5 A;  3E54 A;  5A0W A;  4Z1X A;  1DFA A;  1T9I A;  2VBN B;  1R7M A;  4UN8 A;  2VBL A;  1MOW A;  2FLD A;  5A78 A;  1LWS A;  4Z20 A;  4UN7 G; 
#chains in the Genus database with same CATH topology
 1EF0 A;  3R7P A;  3MXB A;  2XE0 B;  1AF5 A;  3QQY A;  4UN9 G;  4UNA A;  4LQ0 A;  2EX5 A;  2VS7 A;  3MXA A;  2VBJ A;  4AQX A;  4LOX A;  2VBO B;  5E67 A;  4YIT A;  4Z1Z A;  2O7M A;  4UNB A;  4AQU A;  5E5O A;  1U0C A;  1G9Z A;  4UN8 G;  1P8K Z;  5E63 A;  4UNC A;  1G9Y A;  3HYJ A;  1M5X A;  4AAB A;  2VBN A;  1BP7 A;  1UM2 A;  2I3Q A;  4KZS A;  4AAD A;  5AKF A;  2CW7 A;  2CW8 A;  4UN7 A;  2F4L A;  4YIS A;  3C0X A;  2DCH X;  1B24 A;  4D6N A;  5AKN A;  4AAE A;  5A0M B;  3HYI A;  4AAG A;  3MX9 A;  1DQ3 A;  1VDE A;  4D6O A;  2XE0 A;  2VBL B;  1U0D A;  4UN9 A;  3OOR A;  5E5S A;  4YHX A;  3EH8 A;  1JVA A;  3MIS A;  1N3F A;  5AKM A;  4UT0 A;  2VBO A;  3MXB B;  1LWT A;  2I3P A;  2VS8 A;  4EFJ A;  4AAF A;  5AK9 A;  1T9J A;  5A77 A;  2VBJ B;  5A74 A;  3FD2 A;  3UVF A;  3C0W A;  3MIP A;  3OOL A;  3KO2 A;  2QOJ Z;  5A72 A;  1N3E A;  5A0M A;  2AB5 A;  3E54 A;  5A0W A;  4Z1X A;  1DFA A;  1T9I A;  2VBN B;  1R7M A;  4UN8 A;  2VBL A;  1MOW A;  2FLD A;  5A78 A;  1LWS A;  4Z20 A;  4UN7 G; 
#chains in the Genus database with same CATH homology
 1EF0 A;  3R7P A;  3MXB A;  2XE0 B;  1AF5 A;  3QQY A;  4UN9 G;  4UNA A;  4LQ0 A;  2EX5 A;  2VS7 A;  3MXA A;  2VBJ A;  4AQX A;  4LOX A;  2VBO B;  5E67 A;  4YIT A;  4Z1Z A;  2O7M A;  4UNB A;  4AQU A;  5E5O A;  1U0C A;  1G9Z A;  4UN8 G;  1P8K Z;  5E63 A;  4UNC A;  1G9Y A;  3HYJ A;  1M5X A;  4AAB A;  2VBN A;  1BP7 A;  1UM2 A;  2I3Q A;  4AAD A;  5AKF A;  2CW7 A;  2CW8 A;  4UN7 A;  4YIS A;  3C0X A;  2DCH X;  1B24 A;  4D6N A;  5AKN A;  4AAE A;  5A0M B;  3HYI A;  4AAG A;  3MX9 A;  1DQ3 A;  1VDE A;  4D6O A;  2XE0 A;  2VBL B;  1U0D A;  4UN9 A;  3OOR A;  5E5S A;  4YHX A;  3EH8 A;  1JVA A;  3MIS A;  1N3F A;  5AKM A;  4UT0 A;  2VBO A;  3MXB B;  1LWT A;  2I3P A;  2VS8 A;  4EFJ A;  4AAF A;  5AK9 A;  1T9J A;  5A77 A;  2VBJ B;  5A74 A;  3FD2 A;  3UVF A;  3C0W A;  3MIP A;  3OOL A;  3KO2 A;  2QOJ Z;  5A72 A;  1N3E A;  5A0M A;  2AB5 A;  3E54 A;  5A0W A;  4Z1X A;  1DFA A;  1T9I A;  2VBN B;  1R7M A;  4UN8 A;  2VBL A;  1MOW A;  2FLD A;  5A78 A;  1LWS A;  4Z20 A;  4UN7 G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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