2VBOA

Molecular basis of human xpc gene recognition and cleavage by engineered homing endonuclease heterodimers
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
153
structure length
153
Chain Sequence
MNTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSSKFKHRLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDSGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases
pubmed doi rcsb
molecule tags Hydrolase
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 49
structure length 153
sequence length 153
ec nomenclature ec 3.1.-.-:
pdb deposition date 2007-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2vboA00
4UNAA 1JVAA 4UT0A 3C0XA 1U0DA 1U0CA 4UN9A 5A77A 5E5SA 5AKNA 1T9JA 4AAGA 3MXAA 2AB5A 1MOWA 1N3FA 3MX9A 3HYJA 4UNCA 2XE0B 5A72A 2DCHX 3OORA 5A74A 4AQUA 4UN8G 4LOXA 2XE0A 2I3PA 5A0WA 3C0WA 1LWTA 4D6NA 4AAEA 2VBLB 1N3EA 2FLDA 3QQYA 4UN7A 4UNBA 2VBJA 5A0MA 5E5OA 3MXBB 5AK9A 4Z20A 5E67A 3R7PA 2VBLA 2O7MA 4AADA 3UVFA 4UN9G 2QOJZ 1DFAA 3OOLA 3FD2A 4AAFA 4D6OA 3MXBA 2CW8A 2VBJB 5A0MB 4EFJA 2VBNA 4UN7G 4YITA 2I3QA 1B24A 3HYIA 4YISA 2VS7A 4AQXA 1R7MA 2VS8A 3KO2A 1G9ZA 2VBNB 3MISA 2VBOB 4AABA 4Z1XA 2EX5A 1VDEA 1BP7A 5AKMA 4YHXA 1T9IA 4UN8A 1UM2A 3MIPA 3EH8A 2CW7A 2VBOA 1G9YA 1LWSA 1EF0A 5E63A 5AKFA 4Z1ZA 1AF5A 3E54A 1P8KZ 4LQ0A 1DQ3A 1M5XA 5A78A
chains in the Genus database with same CATH superfamily
4UNAA 1JVAA 4UT0A 3C0XA 1U0DA 1U0CA 4UN9A 5A77A 5E5SA 5AKNA 1T9JA 4AAGA 3MXAA 2AB5A 4KZSA 1MOWA 1N3FA 3MX9A 3HYJA 4UNCA 2XE0B 5A72A 2DCHX 3OORA 5A74A 4AQUA 4UN8G 4LOXA 2XE0A 2I3PA 5A0WA 3C0WA 1LWTA 4D6NA 4AAEA 2VBLB 1N3EA 2FLDA 3QQYA 4UN7A 4UNBA 2VBJA 5A0MA 5E5OA 3MXBB 5AK9A 4Z20A 5E67A 3R7PA 2VBLA 2O7MA 4AADA 3UVFA 4UN9G 2QOJZ 1DFAA 3OOLA 3FD2A 4AAFA 4D6OA 3MXBA 2CW8A 2VBJB 5A0MB 4EFJA 2VBNA 4UN7G 4YITA 2I3QA 1B24A 3HYIA 4YISA 2VS7A 4AQXA 1R7MA 2VS8A 3KO2A 1G9ZA 2VBNB 3MISA 2VBOB 4AABA 4Z1XA 2EX5A 1VDEA 2F4LA 1BP7A 5AKMA 4YHXA 1T9IA 4UN8A 1UM2A 3MIPA 3EH8A 2CW7A 2VBOA 1G9YA 1LWSA 1EF0A 5E63A 5AKFA 4Z1ZA 1AF5A 3E54A 1P8KZ 4LQ0A 1DQ3A 1M5XA 5A78A
chains in the Genus database with same CATH topology
4UNAA 1JVAA 4UT0A 3C0XA 1U0DA 1U0CA 4UN9A 5A77A 5E5SA 5AKNA 1T9JA 4AAGA 3MXAA 2AB5A 1MOWA 1N3FA 3MX9A 3HYJA 4UNCA 2XE0B 5A72A 2DCHX 3OORA 5A74A 4AQUA 4UN8G 4LOXA 2XE0A 2I3PA 5A0WA 3C0WA 1LWTA 4D6NA 4AAEA 2VBLB 1N3EA 2FLDA 3QQYA 4UN7A 4UNBA 2VBJA 5A0MA 5E5OA 3MXBB 5AK9A 4Z20A 5E67A 3R7PA 2VBLA 2O7MA 4AADA 3UVFA 4UN9G 2QOJZ 1DFAA 3OOLA 3FD2A 4AAFA 4D6OA 3MXBA 2CW8A 2VBJB 5A0MB 4EFJA 2VBNA 4UN7G 4YITA 2I3QA 1B24A 3HYIA 4YISA 2VS7A 4AQXA 1R7MA 2VS8A 3KO2A 1G9ZA 2VBNB 3MISA 2VBOB 4AABA 4Z1XA 2EX5A 1VDEA 1BP7A 5AKMA 4YHXA 1T9IA 4UN8A 1UM2A 3MIPA 3EH8A 2CW7A 2VBOA 1G9YA 1LWSA 1EF0A 5E63A 5AKFA 4Z1ZA 1AF5A 3E54A 1P8KZ 4LQ0A 1DQ3A 1M5XA 5A78A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UNA A;  1JVA A;  4UT0 A;  3C0X A;  1U0D A;  1U0C A;  4UN9 A;  5A77 A;  5E5S A;  5AKN A;  1T9J A;  4AAG A;  3MXA A;  2AB5 A;  1MOW A;  1N3F A;  3MX9 A;  3HYJ A;  4UNC A;  2XE0 B;  5A72 A;  2DCH X;  3OOR A;  5A74 A;  4AQU A;  4UN8 G;  4LOX A;  2XE0 A;  2I3P A;  5A0W A;  3C0W A;  1LWT A;  4D6N A;  4AAE A;  2VBL B;  1N3E A;  2FLD A;  3QQY A;  4UN7 A;  4UNB A;  2VBJ A;  5A0M A;  5E5O A;  3MXB B;  5AK9 A;  4Z20 A;  5E67 A;  3R7P A;  2VBL A;  2O7M A;  4AAD A;  3UVF A;  4UN9 G;  2QOJ Z;  1DFA A;  3OOL A;  3FD2 A;  4AAF A;  4D6O A;  3MXB A;  2CW8 A;  2VBJ B;  5A0M B;  4EFJ A;  2VBN A;  4UN7 G;  4YIT A;  2I3Q A;  1B24 A;  3HYI A;  4YIS A;  2VS7 A;  4AQX A;  1R7M A;  2VS8 A;  3KO2 A;  1G9Z A;  2VBN B;  3MIS A;  2VBO B;  4AAB A;  4Z1X A;  2EX5 A;  1VDE A;  1BP7 A;  5AKM A;  4YHX A;  1T9I A;  4UN8 A;  1UM2 A;  3MIP A;  3EH8 A;  2CW7 A;  2VBO A;  1G9Y A;  1LWS A;  1EF0 A;  5E63 A;  5AKF A;  4Z1Z A;  1AF5 A;  3E54 A;  1P8K Z;  4LQ0 A;  1DQ3 A;  1M5X A;  5A78 A; 
#chains in the Genus database with same CATH topology
 4UNA A;  1JVA A;  4UT0 A;  3C0X A;  1U0D A;  1U0C A;  4UN9 A;  5A77 A;  5E5S A;  5AKN A;  1T9J A;  4AAG A;  3MXA A;  2AB5 A;  4KZS A;  1MOW A;  1N3F A;  3MX9 A;  3HYJ A;  4UNC A;  2XE0 B;  5A72 A;  2DCH X;  3OOR A;  5A74 A;  4AQU A;  4UN8 G;  4LOX A;  2XE0 A;  2I3P A;  5A0W A;  3C0W A;  1LWT A;  4D6N A;  4AAE A;  2VBL B;  1N3E A;  2FLD A;  3QQY A;  4UN7 A;  4UNB A;  2VBJ A;  5A0M A;  5E5O A;  3MXB B;  5AK9 A;  4Z20 A;  5E67 A;  3R7P A;  2VBL A;  2O7M A;  4AAD A;  3UVF A;  4UN9 G;  2QOJ Z;  1DFA A;  3OOL A;  3FD2 A;  4AAF A;  4D6O A;  3MXB A;  2CW8 A;  2VBJ B;  5A0M B;  4EFJ A;  2VBN A;  4UN7 G;  4YIT A;  2I3Q A;  1B24 A;  3HYI A;  4YIS A;  2VS7 A;  4AQX A;  1R7M A;  2VS8 A;  3KO2 A;  1G9Z A;  2VBN B;  3MIS A;  2VBO B;  4AAB A;  4Z1X A;  2EX5 A;  1VDE A;  2F4L A;  1BP7 A;  5AKM A;  4YHX A;  1T9I A;  4UN8 A;  1UM2 A;  3MIP A;  3EH8 A;  2CW7 A;  2VBO A;  1G9Y A;  1LWS A;  1EF0 A;  5E63 A;  5AKF A;  4Z1Z A;  1AF5 A;  3E54 A;  1P8K Z;  4LQ0 A;  1DQ3 A;  1M5X A;  5A78 A; 
#chains in the Genus database with same CATH homology
 4UNA A;  1JVA A;  4UT0 A;  3C0X A;  1U0D A;  1U0C A;  4UN9 A;  5A77 A;  5E5S A;  5AKN A;  1T9J A;  4AAG A;  3MXA A;  2AB5 A;  1MOW A;  1N3F A;  3MX9 A;  3HYJ A;  4UNC A;  2XE0 B;  5A72 A;  2DCH X;  3OOR A;  5A74 A;  4AQU A;  4UN8 G;  4LOX A;  2XE0 A;  2I3P A;  5A0W A;  3C0W A;  1LWT A;  4D6N A;  4AAE A;  2VBL B;  1N3E A;  2FLD A;  3QQY A;  4UN7 A;  4UNB A;  2VBJ A;  5A0M A;  5E5O A;  3MXB B;  5AK9 A;  4Z20 A;  5E67 A;  3R7P A;  2VBL A;  2O7M A;  4AAD A;  3UVF A;  4UN9 G;  2QOJ Z;  1DFA A;  3OOL A;  3FD2 A;  4AAF A;  4D6O A;  3MXB A;  2CW8 A;  2VBJ B;  5A0M B;  4EFJ A;  2VBN A;  4UN7 G;  4YIT A;  2I3Q A;  1B24 A;  3HYI A;  4YIS A;  2VS7 A;  4AQX A;  1R7M A;  2VS8 A;  3KO2 A;  1G9Z A;  2VBN B;  3MIS A;  2VBO B;  4AAB A;  4Z1X A;  2EX5 A;  1VDE A;  1BP7 A;  5AKM A;  4YHX A;  1T9I A;  4UN8 A;  1UM2 A;  3MIP A;  3EH8 A;  2CW7 A;  2VBO A;  1G9Y A;  1LWS A;  1EF0 A;  5E63 A;  5AKF A;  4Z1Z A;  1AF5 A;  3E54 A;  1P8K Z;  4LQ0 A;  1DQ3 A;  1M5X A;  5A78 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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