2VS8A

The crystal structure of i-dmoi in complex with dna and mn
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
183
structure length
183
Chain Sequence
ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDKTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLNPLPP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering.
pubmed doi rcsb
molecule tags Dna binding protein
source organism Desulfurococcus mobilis
molecule keywords HOMING ENDONUCLEASE I-DMOI
total genus 53
structure length 183
sequence length 183
chains with identical sequence F, K
ec nomenclature ec 3.1.-.-:
pdb deposition date 2008-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF14528 LAGLIDADG_3 LAGLIDADG-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2vs8A01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 2vs8A02
2CW8A 1EF0A 1AF5A 5A0MB 4D6NA 1VDEA 5E63A 3MXBB 3R7PA 3HYIA 1JVAA 4UN8G 1MOWA 3E54A 4Z1ZA 1DQ3A 4YISA 4UN8A 2VS7A 5A77A 4UNBA 2DCHX 4AAGA 1UM2A 4YHXA 2VBLB 2EX5A 3UVFA 5A74A 2VBJB 4AAEA 1LWTA 3C0WA 5E67A 4AAFA 3HYJA 1LWSA 1B24A 5AK9A 1N3FA 3KO2A 2I3QA 2VBOA 4UT0A 5AKNA 2VBNA 5AKMA 2CW7A 5AKFA 3OORA 1R7MA 4AQXA 1N3EA 4YITA 4Z1XA 3MX9A 1P8KZ 5A78A 5E5SA 4AADA 1U0CA 1U0DA 1M5XA 5A0MA 1G9ZA 3MXAA 5E5OA 3MXBA 1T9IA 1BP7A 3OOLA 2XE0A 4UNCA 2QOJZ 4AABA 1DFAA 2AB5A 4EFJA 3QQYA 3EH8A 4UN7G 4UNAA 2I3PA 2VS8A 3MISA 4D6OA 4UN7A 4LOXA 2VBLA 1G9YA 2VBJA 4Z20A 3MIPA 2XE0B 2O7MA 2VBOB 4UN9G 4UN9A 4LQ0A 2VBNB 3C0XA 3FD2A 5A72A 4AQUA 1T9JA 2FLDA 5A0WA
chains in the Genus database with same CATH superfamily
2CW8A 1EF0A 1AF5A 5A0MB 4D6NA 1VDEA 5E63A 3MXBB 3R7PA 3HYIA 1JVAA 4UN8G 1MOWA 3E54A 4Z1ZA 1DQ3A 4YISA 4UN8A 2VS7A 5A77A 4UNBA 2DCHX 4AAGA 1UM2A 4KZSA 4YHXA 2VBLB 2EX5A 3UVFA 5A74A 2VBJB 4AAEA 1LWTA 3C0WA 5E67A 4AAFA 3HYJA 1LWSA 1B24A 5AK9A 1N3FA 3KO2A 2I3QA 2VBOA 4UT0A 5AKNA 2VBNA 5AKMA 2CW7A 5AKFA 3OORA 1R7MA 4AQXA 1N3EA 4YITA 4Z1XA 3MX9A 1P8KZ 5A78A 5E5SA 4AADA 1U0CA 1U0DA 1M5XA 5A0MA 1G9ZA 3MXAA 5E5OA 3MXBA 1T9IA 1BP7A 3OOLA 2F4LA 2XE0A 4UNCA 2QOJZ 4AABA 1DFAA 2AB5A 4EFJA 3QQYA 3EH8A 4UN7G 4UNAA 2I3PA 2VS8A 3MISA 4D6OA 4UN7A 4LOXA 2VBLA 1G9YA 2VBJA 4Z20A 3MIPA 2XE0B 2O7MA 2VBOB 4UN9G 4UN9A 4LQ0A 2VBNB 3C0XA 3FD2A 5A72A 4AQUA 1T9JA 2FLDA 5A0WA
chains in the Genus database with same CATH topology
2CW8A 1EF0A 1AF5A 5A0MB 4D6NA 1VDEA 5E63A 3MXBB 3R7PA 3HYIA 1JVAA 4UN8G 1MOWA 3E54A 4Z1ZA 1DQ3A 4YISA 4UN8A 2VS7A 5A77A 4UNBA 2DCHX 4AAGA 1UM2A 4YHXA 2VBLB 2EX5A 3UVFA 5A74A 2VBJB 4AAEA 1LWTA 3C0WA 5E67A 4AAFA 3HYJA 1LWSA 1B24A 5AK9A 1N3FA 3KO2A 2I3QA 2VBOA 4UT0A 5AKNA 2VBNA 5AKMA 2CW7A 5AKFA 3OORA 1R7MA 4AQXA 1N3EA 4YITA 4Z1XA 3MX9A 1P8KZ 5A78A 5E5SA 4AADA 1U0CA 1U0DA 1M5XA 5A0MA 1G9ZA 3MXAA 5E5OA 3MXBA 1T9IA 1BP7A 3OOLA 2XE0A 4UNCA 2QOJZ 4AABA 1DFAA 2AB5A 4EFJA 3QQYA 3EH8A 4UN7G 4UNAA 2I3PA 2VS8A 3MISA 4D6OA 4UN7A 4LOXA 2VBLA 1G9YA 2VBJA 4Z20A 3MIPA 2XE0B 2O7MA 2VBOB 4UN9G 4UN9A 4LQ0A 2VBNB 3C0XA 3FD2A 5A72A 4AQUA 1T9JA 2FLDA 5A0WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CW8 A;  1EF0 A;  1AF5 A;  5A0M B;  4D6N A;  1VDE A;  5E63 A;  3MXB B;  3R7P A;  3HYI A;  1JVA A;  4UN8 G;  1MOW A;  3E54 A;  4Z1Z A;  1DQ3 A;  4YIS A;  4UN8 A;  2VS7 A;  5A77 A;  4UNB A;  2DCH X;  4AAG A;  1UM2 A;  4YHX A;  2VBL B;  2EX5 A;  3UVF A;  5A74 A;  2VBJ B;  4AAE A;  1LWT A;  3C0W A;  5E67 A;  4AAF A;  3HYJ A;  1LWS A;  1B24 A;  5AK9 A;  1N3F A;  3KO2 A;  2I3Q A;  2VBO A;  4UT0 A;  5AKN A;  2VBN A;  5AKM A;  2CW7 A;  5AKF A;  3OOR A;  1R7M A;  4AQX A;  1N3E A;  4YIT A;  4Z1X A;  3MX9 A;  1P8K Z;  5A78 A;  5E5S A;  4AAD A;  1U0C A;  1U0D A;  1M5X A;  5A0M A;  1G9Z A;  3MXA A;  5E5O A;  3MXB A;  1T9I A;  1BP7 A;  3OOL A;  2XE0 A;  4UNC A;  2QOJ Z;  4AAB A;  1DFA A;  2AB5 A;  4EFJ A;  3QQY A;  3EH8 A;  4UN7 G;  4UNA A;  2I3P A;  2VS8 A;  3MIS A;  4D6O A;  4UN7 A;  4LOX A;  2VBL A;  1G9Y A;  2VBJ A;  4Z20 A;  3MIP A;  2XE0 B;  2O7M A;  2VBO B;  4UN9 G;  4UN9 A;  4LQ0 A;  2VBN B;  3C0X A;  3FD2 A;  5A72 A;  4AQU A;  1T9J A;  2FLD A;  5A0W A; 
#chains in the Genus database with same CATH topology
 2CW8 A;  1EF0 A;  1AF5 A;  5A0M B;  4D6N A;  1VDE A;  5E63 A;  3MXB B;  3R7P A;  3HYI A;  1JVA A;  4UN8 G;  1MOW A;  3E54 A;  4Z1Z A;  1DQ3 A;  4YIS A;  4UN8 A;  2VS7 A;  5A77 A;  4UNB A;  2DCH X;  4AAG A;  1UM2 A;  4KZS A;  4YHX A;  2VBL B;  2EX5 A;  3UVF A;  5A74 A;  2VBJ B;  4AAE A;  1LWT A;  3C0W A;  5E67 A;  4AAF A;  3HYJ A;  1LWS A;  1B24 A;  5AK9 A;  1N3F A;  3KO2 A;  2I3Q A;  2VBO A;  4UT0 A;  5AKN A;  2VBN A;  5AKM A;  2CW7 A;  5AKF A;  3OOR A;  1R7M A;  4AQX A;  1N3E A;  4YIT A;  4Z1X A;  3MX9 A;  1P8K Z;  5A78 A;  5E5S A;  4AAD A;  1U0C A;  1U0D A;  1M5X A;  5A0M A;  1G9Z A;  3MXA A;  5E5O A;  3MXB A;  1T9I A;  1BP7 A;  3OOL A;  2F4L A;  2XE0 A;  4UNC A;  2QOJ Z;  4AAB A;  1DFA A;  2AB5 A;  4EFJ A;  3QQY A;  3EH8 A;  4UN7 G;  4UNA A;  2I3P A;  2VS8 A;  3MIS A;  4D6O A;  4UN7 A;  4LOX A;  2VBL A;  1G9Y A;  2VBJ A;  4Z20 A;  3MIP A;  2XE0 B;  2O7M A;  2VBO B;  4UN9 G;  4UN9 A;  4LQ0 A;  2VBN B;  3C0X A;  3FD2 A;  5A72 A;  4AQU A;  1T9J A;  2FLD A;  5A0W A; 
#chains in the Genus database with same CATH homology
 2CW8 A;  1EF0 A;  1AF5 A;  5A0M B;  4D6N A;  1VDE A;  5E63 A;  3MXB B;  3R7P A;  3HYI A;  1JVA A;  4UN8 G;  1MOW A;  3E54 A;  4Z1Z A;  1DQ3 A;  4YIS A;  4UN8 A;  2VS7 A;  5A77 A;  4UNB A;  2DCH X;  4AAG A;  1UM2 A;  4YHX A;  2VBL B;  2EX5 A;  3UVF A;  5A74 A;  2VBJ B;  4AAE A;  1LWT A;  3C0W A;  5E67 A;  4AAF A;  3HYJ A;  1LWS A;  1B24 A;  5AK9 A;  1N3F A;  3KO2 A;  2I3Q A;  2VBO A;  4UT0 A;  5AKN A;  2VBN A;  5AKM A;  2CW7 A;  5AKF A;  3OOR A;  1R7M A;  4AQX A;  1N3E A;  4YIT A;  4Z1X A;  3MX9 A;  1P8K Z;  5A78 A;  5E5S A;  4AAD A;  1U0C A;  1U0D A;  1M5X A;  5A0M A;  1G9Z A;  3MXA A;  5E5O A;  3MXB A;  1T9I A;  1BP7 A;  3OOL A;  2XE0 A;  4UNC A;  2QOJ Z;  4AAB A;  1DFA A;  2AB5 A;  4EFJ A;  3QQY A;  3EH8 A;  4UN7 G;  4UNA A;  2I3P A;  2VS8 A;  3MIS A;  4D6O A;  4UN7 A;  4LOX A;  2VBL A;  1G9Y A;  2VBJ A;  4Z20 A;  3MIP A;  2XE0 B;  2O7M A;  2VBO B;  4UN9 G;  4UN9 A;  4LQ0 A;  2VBN B;  3C0X A;  3FD2 A;  5A72 A;  4AQU A;  1T9J A;  2FLD A;  5A0W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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