3EH8A

Crystal structure of y2 i-anii variant (f13y/s111y)/dna complex with calcium
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
254
structure length
254
Chain Sequence
GSDLTYAYLVGLYEGDGYFSITKKGKYLTYELGIELSIKDVQLIYKIKKILGIGIVSFRKRNEIEMVALRIRDKNHLKSKILPIFEKYPMFSNKQYDYLRFRNALLSGIIYLEDLPDYTRSDEPLNSIESIINTSYFSAWLVGFIEAEGCFSVYKLNKDDDYLIASFDIAQRDGDILISAIRKYLSFTTKVYLDKTNCSKLKVTSVRSVENIIKFLQNAPVKLLGNKKLQYKLWLKQLRKISRYSEKIKIPSNY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Optimization of in vivo activity of a bifunctional homing endonuclease and maturase reverses evolutionary degradation.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Emericella nidulans
molecule keywords Intron-encoded DNA endonuclease I-AniI
total genus 70
structure length 254
sequence length 254
chains with identical sequence D, G
ec nomenclature ec 3.1.-.-:
pdb deposition date 2008-09-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3eh8A01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3eh8A02
4UN9A 5A77A 3EH8A 4LQ0A 2VBNA 3C0XA 1G9ZA 5A0MB 2XE0A 3E54A 5E5SA 2AB5A 2VBNB 5A74A 4UN8G 1UM2A 5E63A 5AKFA 2VBOA 4UN9G 3MISA 3QQYA 1G9YA 2XE0B 4UNAA 3HYIA 4LOXA 2FLDA 1AF5A 3OOLA 1N3FA 2QOJZ 1T9IA 2VBOB 3OORA 2VS8A 1U0DA 2CW7A 1M5XA 1LWTA 1N3EA 4AAFA 4Z20A 1JVAA 3MX9A 5A78A 2DCHX 3HYJA 4AQXA 1BP7A 4UT0A 1LWSA 3MIPA 2I3QA 1B24A 4AAGA 4AAEA 4YHXA 4UN7A 3MXBA 4AADA 3R7PA 1DQ3A 1VDEA 5AK9A 5AKNA 2VS7A 3C0WA 4AABA 1MOWA 4EFJA 1U0CA 2VBJA 5A0MA 4UN7G 4Z1ZA 4UNCA 4D6NA 1T9JA 2VBLA 5AKMA 2VBJB 3KO2A 5E5OA 4Z1XA 2VBLB 4YITA 3FD2A 4UNBA 4YISA 3MXBB 1R7MA 4AQUA 5A72A 4D6OA 3UVFA 2EX5A 1EF0A 1P8KZ 5A0WA 3MXAA 1DFAA 5E67A 4UN8A 2O7MA 2CW8A 2I3PA
chains in the Genus database with same CATH superfamily
4UN9A 5A77A 3EH8A 4LQ0A 2VBNA 3C0XA 1G9ZA 5A0MB 2XE0A 3E54A 5E5SA 2AB5A 2VBNB 5A74A 4UN8G 1UM2A 5E63A 5AKFA 2VBOA 4UN9G 3MISA 3QQYA 1G9YA 2XE0B 4UNAA 3HYIA 4LOXA 2FLDA 1AF5A 3OOLA 1N3FA 2QOJZ 1T9IA 2VBOB 3OORA 2VS8A 1U0DA 2CW7A 1M5XA 1LWTA 1N3EA 4AAFA 4Z20A 1JVAA 3MX9A 5A78A 2DCHX 3HYJA 4AQXA 1BP7A 4UT0A 1LWSA 3MIPA 2I3QA 1B24A 4AAGA 4AAEA 4YHXA 4UN7A 3MXBA 4AADA 3R7PA 1DQ3A 1VDEA 5AK9A 5AKNA 2VS7A 3C0WA 4AABA 1MOWA 4EFJA 1U0CA 2VBJA 5A0MA 4UN7G 4Z1ZA 4UNCA 4D6NA 1T9JA 2VBLA 5AKMA 2VBJB 3KO2A 5E5OA 4KZSA 4Z1XA 2VBLB 4YITA 3FD2A 2F4LA 4UNBA 4YISA 3MXBB 1R7MA 4AQUA 5A72A 4D6OA 3UVFA 2EX5A 1EF0A 1P8KZ 5A0WA 3MXAA 1DFAA 5E67A 4UN8A 2O7MA 2CW8A 2I3PA
chains in the Genus database with same CATH topology
4UN9A 5A77A 3EH8A 4LQ0A 2VBNA 3C0XA 1G9ZA 5A0MB 2XE0A 3E54A 5E5SA 2AB5A 2VBNB 5A74A 4UN8G 1UM2A 5E63A 5AKFA 2VBOA 4UN9G 3MISA 3QQYA 1G9YA 2XE0B 4UNAA 3HYIA 4LOXA 2FLDA 1AF5A 3OOLA 1N3FA 2QOJZ 1T9IA 2VBOB 3OORA 2VS8A 1U0DA 2CW7A 1M5XA 1LWTA 1N3EA 4AAFA 4Z20A 1JVAA 3MX9A 5A78A 2DCHX 3HYJA 4AQXA 1BP7A 4UT0A 1LWSA 3MIPA 2I3QA 1B24A 4AAGA 4AAEA 4YHXA 4UN7A 3MXBA 4AADA 3R7PA 1DQ3A 1VDEA 5AK9A 5AKNA 2VS7A 3C0WA 4AABA 1MOWA 4EFJA 1U0CA 2VBJA 5A0MA 4UN7G 4Z1ZA 4UNCA 4D6NA 1T9JA 2VBLA 5AKMA 2VBJB 3KO2A 5E5OA 4Z1XA 2VBLB 4YITA 3FD2A 4UNBA 4YISA 3MXBB 1R7MA 4AQUA 5A72A 4D6OA 3UVFA 2EX5A 1EF0A 1P8KZ 5A0WA 3MXAA 1DFAA 5E67A 4UN8A 2O7MA 2CW8A 2I3PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UN9 A;  5A77 A;  3EH8 A;  4LQ0 A;  2VBN A;  3C0X A;  1G9Z A;  5A0M B;  2XE0 A;  3E54 A;  5E5S A;  2AB5 A;  2VBN B;  5A74 A;  4UN8 G;  1UM2 A;  5E63 A;  5AKF A;  2VBO A;  4UN9 G;  3MIS A;  3QQY A;  1G9Y A;  2XE0 B;  4UNA A;  3HYI A;  4LOX A;  2FLD A;  1AF5 A;  3OOL A;  1N3F A;  2QOJ Z;  1T9I A;  2VBO B;  3OOR A;  2VS8 A;  1U0D A;  2CW7 A;  1M5X A;  1LWT A;  1N3E A;  4AAF A;  4Z20 A;  1JVA A;  3MX9 A;  5A78 A;  2DCH X;  3HYJ A;  4AQX A;  1BP7 A;  4UT0 A;  1LWS A;  3MIP A;  2I3Q A;  1B24 A;  4AAG A;  4AAE A;  4YHX A;  4UN7 A;  3MXB A;  4AAD A;  3R7P A;  1DQ3 A;  1VDE A;  5AK9 A;  5AKN A;  2VS7 A;  3C0W A;  4AAB A;  1MOW A;  4EFJ A;  1U0C A;  2VBJ A;  5A0M A;  4UN7 G;  4Z1Z A;  4UNC A;  4D6N A;  1T9J A;  2VBL A;  5AKM A;  2VBJ B;  3KO2 A;  5E5O A;  4Z1X A;  2VBL B;  4YIT A;  3FD2 A;  4UNB A;  4YIS A;  3MXB B;  1R7M A;  4AQU A;  5A72 A;  4D6O A;  3UVF A;  2EX5 A;  1EF0 A;  1P8K Z;  5A0W A;  3MXA A;  1DFA A;  5E67 A;  4UN8 A;  2O7M A;  2CW8 A;  2I3P A; 
#chains in the Genus database with same CATH topology
 4UN9 A;  5A77 A;  3EH8 A;  4LQ0 A;  2VBN A;  3C0X A;  1G9Z A;  5A0M B;  2XE0 A;  3E54 A;  5E5S A;  2AB5 A;  2VBN B;  5A74 A;  4UN8 G;  1UM2 A;  5E63 A;  5AKF A;  2VBO A;  4UN9 G;  3MIS A;  3QQY A;  1G9Y A;  2XE0 B;  4UNA A;  3HYI A;  4LOX A;  2FLD A;  1AF5 A;  3OOL A;  1N3F A;  2QOJ Z;  1T9I A;  2VBO B;  3OOR A;  2VS8 A;  1U0D A;  2CW7 A;  1M5X A;  1LWT A;  1N3E A;  4AAF A;  4Z20 A;  1JVA A;  3MX9 A;  5A78 A;  2DCH X;  3HYJ A;  4AQX A;  1BP7 A;  4UT0 A;  1LWS A;  3MIP A;  2I3Q A;  1B24 A;  4AAG A;  4AAE A;  4YHX A;  4UN7 A;  3MXB A;  4AAD A;  3R7P A;  1DQ3 A;  1VDE A;  5AK9 A;  5AKN A;  2VS7 A;  3C0W A;  4AAB A;  1MOW A;  4EFJ A;  1U0C A;  2VBJ A;  5A0M A;  4UN7 G;  4Z1Z A;  4UNC A;  4D6N A;  1T9J A;  2VBL A;  5AKM A;  2VBJ B;  3KO2 A;  5E5O A;  4KZS A;  4Z1X A;  2VBL B;  4YIT A;  3FD2 A;  2F4L A;  4UNB A;  4YIS A;  3MXB B;  1R7M A;  4AQU A;  5A72 A;  4D6O A;  3UVF A;  2EX5 A;  1EF0 A;  1P8K Z;  5A0W A;  3MXA A;  1DFA A;  5E67 A;  4UN8 A;  2O7M A;  2CW8 A;  2I3P A; 
#chains in the Genus database with same CATH homology
 4UN9 A;  5A77 A;  3EH8 A;  4LQ0 A;  2VBN A;  3C0X A;  1G9Z A;  5A0M B;  2XE0 A;  3E54 A;  5E5S A;  2AB5 A;  2VBN B;  5A74 A;  4UN8 G;  1UM2 A;  5E63 A;  5AKF A;  2VBO A;  4UN9 G;  3MIS A;  3QQY A;  1G9Y A;  2XE0 B;  4UNA A;  3HYI A;  4LOX A;  2FLD A;  1AF5 A;  3OOL A;  1N3F A;  2QOJ Z;  1T9I A;  2VBO B;  3OOR A;  2VS8 A;  1U0D A;  2CW7 A;  1M5X A;  1LWT A;  1N3E A;  4AAF A;  4Z20 A;  1JVA A;  3MX9 A;  5A78 A;  2DCH X;  3HYJ A;  4AQX A;  1BP7 A;  4UT0 A;  1LWS A;  3MIP A;  2I3Q A;  1B24 A;  4AAG A;  4AAE A;  4YHX A;  4UN7 A;  3MXB A;  4AAD A;  3R7P A;  1DQ3 A;  1VDE A;  5AK9 A;  5AKN A;  2VS7 A;  3C0W A;  4AAB A;  1MOW A;  4EFJ A;  1U0C A;  2VBJ A;  5A0M A;  4UN7 G;  4Z1Z A;  4UNC A;  4D6N A;  1T9J A;  2VBL A;  5AKM A;  2VBJ B;  3KO2 A;  5E5O A;  4Z1X A;  2VBL B;  4YIT A;  3FD2 A;  4UNB A;  4YIS A;  3MXB B;  1R7M A;  4AQU A;  5A72 A;  4D6O A;  3UVF A;  2EX5 A;  1EF0 A;  1P8K Z;  5A0W A;  3MXA A;  1DFA A;  5E67 A;  4UN8 A;  2O7M A;  2CW8 A;  2I3P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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