3MFLA

Axial ligand swapping in double mutant maintains intradiol-cleavage chemistry in protocatechuate 3,4-dioxygenase
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
200
structure length
200
Chain Sequence
PIELLPETPSQTAGPYVHIGLALEAAGNPTRDQEIWNRLAKPDAPGEHILLLGQVYDGNGHLVRDSFLEVWQADANGEYQDAYNLENAFNSFGRTATTFDAGEWTLHTVKPGVVNNAAGVPMAPHINISLFARGINIHLHTRLYFDDEAQANAKCPVLNLIEQPQRRETLIAKRCEVDGKTAYRFDIRIQGEGETVFFDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
rcsb
molecule tags Oxidoreductase
source organism Pseudomonas putida
molecule keywords Protocatechuate 3,4-dioxygenase alpha chain
total genus 43
structure length 200
sequence length 200
chains with identical sequence B, C
ec nomenclature ec 1.13.11.3: Protocatechuate 3,4-dioxygenase.
pdb deposition date 2010-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00775 Dioxygenase_C Dioxygenase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.130.10 Mainly Beta Sandwich Protocatechuate 3,4-Dioxygenase, subunit A Aromatic compound dioxygenase 3mflA00
1EOCA 1EOAA 4WHQB 2BUVA 2XSRA 2BUWB 3HHXA 3PCIM 3HJQA 4WHPB 3T67M 3HGIA 3PCEM 2BURB 3PCBA 1TMXA 3LKTM 3PCJM 3MI1M 1EO2B 3O6JA 3PCCM 3I4VA 1DLMA 1DLQA 2XSVA 3PCKA 2BUTA 4WHOD 3LMXA 3PCNM 1YKNA 1DMHA 3I51A 2BUQA 3PCDA 3PCHA 3MI5M 3MV4A 3PCLM 3LXVM 3PCFA 1EOBB 3PCMM 3O5UA 4WHRB 2BUXA 3T63M 1YKMA 3O6RA 3PCAA 2BV0B 2BUZA 3O32A 1YKLA 3MV6A 3PCGM 3TH1A 2BUMB 2BUUA 2BUTB 1YKKA 3HJ8A 3I4YA 4WHOB 1EO9A 4ILTA 2BUYA 3MFLM 1YKOB 3HHYA 1EOCB 1EOAB 2BUVB 3PCBM 1YKPA 2AZQA 4WHSA 4WHRF 3PCKM 4WHPD 1DLTA 2PCDA 1S9AA 4WHQA 3PCMA 2BUWA 3LMXM 3N9TA 4WHPA 3PCDM 3PCHM 2BURA 3PCIA 2BOYA 3PCFM 1YKNB 1EO2A 3HKPA 2BUQB 3T67A 3PCGA 3PCEA 3HJSA 3LKTA 3PCJA 3MI1A 3PCAM 3PCCA 3MV6M 2XSUA 2BUXB 4WHSD 1YKMB 3MFLA 2BUZB 1YKLB 2BUUB 3PCNA 1EOBA 3MI5A 1YKKB 4WHRA 3PCLA 3LXVA 1EO9B 2BV0A 2BUYB 2BUMA 3MV4M 3T63A 5TD3A 4ILVA 4WHOA 1YKPB 4WHSB 2PCDM 1YKOA
chains in the Genus database with same CATH superfamily
1EOCA 1EOAA 4WHQB 2BUVA 2XSRA 2BUWB 3HHXA 3PCIM 3HJQA 4WHPB 3T67M 3HGIA 3PCEM 2BURB 3PCBA 1TMXA 3LKTM 3PCJM 3MI1M 1EO2B 3O6JA 3PCCM 3I4VA 1DLMA 1DLQA 2XSVA 3PCKA 2BUTA 4WHOD 3LMXA 3PCNM 1YKNA 1DMHA 3I51A 2BUQA 3PCDA 3PCHA 3MI5M 3MV4A 3PCLM 3LXVM 3PCFA 1EOBB 3PCMM 3O5UA 4WHRB 2BUXA 3T63M 1YKMA 3O6RA 3PCAA 2BV0B 2BUZA 3O32A 1YKLA 3MV6A 3PCGM 3TH1A 2BUMB 2BUUA 2BUTB 1YKKA 3HJ8A 3I4YA 4WHOB 1EO9A 4ILTA 2BUYA 3MFLM 1YKOB 3HHYA 1EOCB 1EOAB 2BUVB 3PCBM 1YKPA 2AZQA 4WHSA 4WHRF 3PCKM 4WHPD 1DLTA 2PCDA 1S9AA 4WHQA 3PCMA 2BUWA 3LMXM 3N9TA 4WHPA 3PCDM 3PCHM 2BURA 3PCIA 2BOYA 3PCFM 1YKNB 1EO2A 3HKPA 2BUQB 3T67A 3PCGA 3PCEA 3HJSA 3LKTA 3PCJA 3MI1A 3PCAM 3PCCA 3MV6M 2XSUA 2BUXB 4WHSD 1YKMB 3MFLA 2BUZB 1YKLB 2BUUB 3PCNA 1EOBA 3MI5A 1YKKB 4WHRA 3PCLA 3LXVA 1EO9B 2BV0A 2BUYB 2BUMA 3MV4M 3T63A 5TD3A 4ILVA 4WHOA 1YKPB 4WHSB 2PCDM 1YKOA
chains in the Genus database with same CATH topology
1EOCA 1EOAA 4WHQB 2BUVA 2XSRA 2BUWB 3HHXA 3PCIM 3HJQA 4WHPB 3T67M 3HGIA 3PCEM 2BURB 3PCBA 1TMXA 3LKTM 3PCJM 3MI1M 1EO2B 3O6JA 3PCCM 3I4VA 1DLMA 1DLQA 2XSVA 3PCKA 2BUTA 4WHOD 3LMXA 3PCNM 1YKNA 1DMHA 3I51A 2BUQA 3PCDA 3PCHA 3MI5M 3MV4A 3PCLM 3LXVM 3PCFA 1EOBB 3PCMM 3O5UA 4WHRB 2BUXA 3T63M 1YKMA 3O6RA 3PCAA 2BV0B 2BUZA 3O32A 1YKLA 3MV6A 3PCGM 3TH1A 2BUMB 2BUUA 2BUTB 1YKKA 3HJ8A 3I4YA 4WHOB 1EO9A 4ILTA 2BUYA 3MFLM 1YKOB 3HHYA 1EOCB 1EOAB 2BUVB 3PCBM 1YKPA 2AZQA 4WHSA 4WHRF 3PCKM 4WHPD 1DLTA 2PCDA 1S9AA 4WHQA 3PCMA 2BUWA 3LMXM 3N9TA 4WHPA 3PCDM 3PCHM 2BURA 3PCIA 2BOYA 3PCFM 1YKNB 1EO2A 3HKPA 2BUQB 3T67A 3PCGA 3PCEA 3HJSA 3LKTA 3PCJA 3MI1A 3PCAM 3PCCA 3MV6M 2XSUA 2BUXB 4WHSD 1YKMB 3MFLA 2BUZB 1YKLB 2BUUB 3PCNA 1EOBA 3MI5A 1YKKB 4WHRA 3PCLA 3LXVA 1EO9B 2BV0A 2BUYB 2BUMA 3MV4M 3T63A 5TD3A 4ILVA 4WHOA 1YKPB 4WHSB 2PCDM 1YKOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EOC A;  1EOA A;  4WHQ B;  2BUV A;  2XSR A;  2BUW B;  3HHX A;  3PCI M;  3HJQ A;  4WHP B;  3T67 M;  3HGI A;  3PCE M;  2BUR B;  3PCB A;  1TMX A;  3LKT M;  3PCJ M;  3MI1 M;  1EO2 B;  3O6J A;  3PCC M;  3I4V A;  1DLM A;  1DLQ A;  2XSV A;  3PCK A;  2BUT A;  4WHO D;  3LMX A;  3PCN M;  1YKN A;  1DMH A;  3I51 A;  2BUQ A;  3PCD A;  3PCH A;  3MI5 M;  3MV4 A;  3PCL M;  3LXV M;  3PCF A;  1EOB B;  3PCM M;  3O5U A;  4WHR B;  2BUX A;  3T63 M;  1YKM A;  3O6R A;  3PCA A;  2BV0 B;  2BUZ A;  3O32 A;  1YKL A;  3MV6 A;  3PCG M;  3TH1 A;  2BUM B;  2BUU A;  2BUT B;  1YKK A;  3HJ8 A;  3I4Y A;  4WHO B;  1EO9 A;  4ILT A;  2BUY A;  3MFL M;  1YKO B;  3HHY A;  1EOC B;  1EOA B;  2BUV B;  3PCB M;  1YKP A;  2AZQ A;  4WHS A;  4WHR F;  3PCK M;  4WHP D;  1DLT A;  2PCD A;  1S9A A;  4WHQ A;  3PCM A;  2BUW A;  3LMX M;  3N9T A;  4WHP A;  3PCD M;  3PCH M;  2BUR A;  3PCI A;  2BOY A;  3PCF M;  1YKN B;  1EO2 A;  3HKP A;  2BUQ B;  3T67 A;  3PCG A;  3PCE A;  3HJS A;  3LKT A;  3PCJ A;  3MI1 A;  3PCA M;  3PCC A;  3MV6 M;  2XSU A;  2BUX B;  4WHS D;  1YKM B;  3MFL A;  2BUZ B;  1YKL B;  2BUU B;  3PCN A;  1EOB A;  3MI5 A;  1YKK B;  4WHR A;  3PCL A;  3LXV A;  1EO9 B;  2BV0 A;  2BUY B;  2BUM A;  3MV4 M;  3T63 A;  5TD3 A;  4ILV A;  4WHO A;  1YKP B;  4WHS B;  2PCD M;  1YKO A; 
#chains in the Genus database with same CATH topology
 1EOC A;  1EOA A;  4WHQ B;  2BUV A;  2XSR A;  2BUW B;  3HHX A;  3PCI M;  3HJQ A;  4WHP B;  3T67 M;  3HGI A;  3PCE M;  2BUR B;  3PCB A;  1TMX A;  3LKT M;  3PCJ M;  3MI1 M;  1EO2 B;  3O6J A;  3PCC M;  3I4V A;  1DLM A;  1DLQ A;  2XSV A;  3PCK A;  2BUT A;  4WHO D;  3LMX A;  3PCN M;  1YKN A;  1DMH A;  3I51 A;  2BUQ A;  3PCD A;  3PCH A;  3MI5 M;  3MV4 A;  3PCL M;  3LXV M;  3PCF A;  1EOB B;  3PCM M;  3O5U A;  4WHR B;  2BUX A;  3T63 M;  1YKM A;  3O6R A;  3PCA A;  2BV0 B;  2BUZ A;  3O32 A;  1YKL A;  3MV6 A;  3PCG M;  3TH1 A;  2BUM B;  2BUU A;  2BUT B;  1YKK A;  3HJ8 A;  3I4Y A;  4WHO B;  1EO9 A;  4ILT A;  2BUY A;  3MFL M;  1YKO B;  3HHY A;  1EOC B;  1EOA B;  2BUV B;  3PCB M;  1YKP A;  2AZQ A;  4WHS A;  4WHR F;  3PCK M;  4WHP D;  1DLT A;  2PCD A;  1S9A A;  4WHQ A;  3PCM A;  2BUW A;  3LMX M;  3N9T A;  4WHP A;  3PCD M;  3PCH M;  2BUR A;  3PCI A;  2BOY A;  3PCF M;  1YKN B;  1EO2 A;  3HKP A;  2BUQ B;  3T67 A;  3PCG A;  3PCE A;  3HJS A;  3LKT A;  3PCJ A;  3MI1 A;  3PCA M;  3PCC A;  3MV6 M;  2XSU A;  2BUX B;  4WHS D;  1YKM B;  3MFL A;  2BUZ B;  1YKL B;  2BUU B;  3PCN A;  1EOB A;  3MI5 A;  1YKK B;  4WHR A;  3PCL A;  3LXV A;  1EO9 B;  2BV0 A;  2BUY B;  2BUM A;  3MV4 M;  3T63 A;  5TD3 A;  4ILV A;  4WHO A;  1YKP B;  4WHS B;  2PCD M;  1YKO A; 
#chains in the Genus database with same CATH homology
 1EOC A;  1EOA A;  4WHQ B;  2BUV A;  2XSR A;  2BUW B;  3HHX A;  3PCI M;  3HJQ A;  4WHP B;  3T67 M;  3HGI A;  3PCE M;  2BUR B;  3PCB A;  1TMX A;  3LKT M;  3PCJ M;  3MI1 M;  1EO2 B;  3O6J A;  3PCC M;  3I4V A;  1DLM A;  1DLQ A;  2XSV A;  3PCK A;  2BUT A;  4WHO D;  3LMX A;  3PCN M;  1YKN A;  1DMH A;  3I51 A;  2BUQ A;  3PCD A;  3PCH A;  3MI5 M;  3MV4 A;  3PCL M;  3LXV M;  3PCF A;  1EOB B;  3PCM M;  3O5U A;  4WHR B;  2BUX A;  3T63 M;  1YKM A;  3O6R A;  3PCA A;  2BV0 B;  2BUZ A;  3O32 A;  1YKL A;  3MV6 A;  3PCG M;  3TH1 A;  2BUM B;  2BUU A;  2BUT B;  1YKK A;  3HJ8 A;  3I4Y A;  4WHO B;  1EO9 A;  4ILT A;  2BUY A;  3MFL M;  1YKO B;  3HHY A;  1EOC B;  1EOA B;  2BUV B;  3PCB M;  1YKP A;  2AZQ A;  4WHS A;  4WHR F;  3PCK M;  4WHP D;  1DLT A;  2PCD A;  1S9A A;  4WHQ A;  3PCM A;  2BUW A;  3LMX M;  3N9T A;  4WHP A;  3PCD M;  3PCH M;  2BUR A;  3PCI A;  2BOY A;  3PCF M;  1YKN B;  1EO2 A;  3HKP A;  2BUQ B;  3T67 A;  3PCG A;  3PCE A;  3HJS A;  3LKT A;  3PCJ A;  3MI1 A;  3PCA M;  3PCC A;  3MV6 M;  2XSU A;  2BUX B;  4WHS D;  1YKM B;  3MFL A;  2BUZ B;  1YKL B;  2BUU B;  3PCN A;  1EOB A;  3MI5 A;  1YKK B;  4WHR A;  3PCL A;  3LXV A;  1EO9 B;  2BV0 A;  2BUY B;  2BUM A;  3MV4 M;  3T63 A;  5TD3 A;  4ILV A;  4WHO A;  1YKP B;  4WHS B;  2PCD M;  1YKO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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