3MFLM

Axial ligand swapping in double mutant maintains intradiol-cleavage chemistry in protocatechuate 3,4-dioxygenase
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
238
structure length
238
Chain Sequence
PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFNNGGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPHPWRNGPNDWRPAHIYFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFENC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
rcsb
molecule tags Oxidoreductase
source organism Pseudomonas putida
molecule keywords Protocatechuate 3,4-dioxygenase alpha chain
total genus 56
structure length 238
sequence length 238
chains with identical sequence N, O
ec nomenclature ec 1.13.11.3: Protocatechuate 3,4-dioxygenase.
pdb deposition date 2010-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00775 Dioxygenase_C Dioxygenase
M PF12391 PCDO_beta_N Protocatechuate 3,4-dioxygenase beta subunit N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.130.10 Mainly Beta Sandwich Protocatechuate 3,4-Dioxygenase, subunit A Aromatic compound dioxygenase 3mflM00
2BV0B 3I4VA 1YKKA 4WHRF 1EO2B 3PCLA 3T67M 3PCDM 3MV6M 4WHPA 2BUZB 3HJ8A 1YKMA 3PCHA 4WHOD 3T63A 1YKLB 3HGIA 1EOBB 3PCJM 3MV4M 3LMXM 1YKNB 1DLQA 3HKPA 2BUVA 3PCKA 1YKOA 2BUMA 1YKKB 3LXVA 3HHXA 2BUWA 1EOCA 2BUUA 3N9TA 2BUYA 3PCCA 1S9AA 2XSUA 3PCGM 3PCEM 4ILTA 3T63M 4WHSA 3PCIA 4WHPB 3MFLA 2AZQA 1YKMB 3PCMA 3O5UA 3MI5M 3LKTM 3O6RA 1EOAA 2BOYA 3PCBM 3LXVM 2BUVB 1TMXA 3TH1A 1YKOB 2BUMB 3I4YA 4WHQA 2BUWB 3PCNA 1YKPA 3MI1A 1EOCB 2BUUB 3PCLM 3PCAA 2BUYB 2BUQA 5TD3A 3HJSA 4WHPD 2BUXA 2BUTA 4WHSB 3O6JA 3PCHM 1EO9A 3PCFA 2XSRA 3T67A 4WHRA 2BURA 1EOAB 2XSVA 3PCKM 1YKNA 3PCAM 4WHQB 4WHOA 3MV4A 3LMXA 1YKPB 2BUQB 3PCCM 4WHSD 2BV0A 3HJQA 3I51A 2BUXB 2PCDA 1DLTA 2BUTB 1DMHA 3PCIM 3MFLM 3PCFM 3PCMM 1EO2A 1EO9B 4WHRB 2BURB 1DLMA 3PCGA 3PCEA 2BUZA 3PCDA 4ILVA 1YKLA 3MV6A 1EOBA 3MI5A 3LKTA 3PCNM 4WHOB 3MI1M 3O32A 3PCJA 3PCBA 2PCDM 3HHYA
chains in the Genus database with same CATH superfamily
2BV0B 3I4VA 1YKKA 4WHRF 1EO2B 3PCLA 3T67M 3PCDM 3MV6M 4WHPA 2BUZB 3HJ8A 1YKMA 3PCHA 4WHOD 3T63A 1YKLB 3HGIA 1EOBB 3PCJM 3MV4M 3LMXM 1YKNB 1DLQA 3HKPA 2BUVA 3PCKA 1YKOA 2BUMA 1YKKB 3LXVA 3HHXA 2BUWA 1EOCA 2BUUA 3N9TA 2BUYA 3PCCA 1S9AA 2XSUA 3PCGM 3PCEM 4ILTA 3T63M 4WHSA 3PCIA 4WHPB 3MFLA 2AZQA 1YKMB 3PCMA 3O5UA 3MI5M 3LKTM 3O6RA 1EOAA 2BOYA 3PCBM 3LXVM 2BUVB 1TMXA 3TH1A 1YKOB 2BUMB 3I4YA 4WHQA 2BUWB 3PCNA 1YKPA 3MI1A 1EOCB 2BUUB 3PCLM 3PCAA 2BUYB 2BUQA 5TD3A 3HJSA 4WHPD 2BUXA 2BUTA 4WHSB 3O6JA 3PCHM 1EO9A 3PCFA 2XSRA 3T67A 4WHRA 2BURA 1EOAB 2XSVA 3PCKM 1YKNA 3PCAM 4WHQB 4WHOA 3MV4A 3LMXA 1YKPB 2BUQB 3PCCM 4WHSD 2BV0A 3HJQA 3I51A 2BUXB 2PCDA 1DLTA 2BUTB 1DMHA 3PCIM 3MFLM 3PCFM 3PCMM 1EO2A 1EO9B 4WHRB 2BURB 1DLMA 3PCGA 3PCEA 2BUZA 3PCDA 4ILVA 1YKLA 3MV6A 1EOBA 3MI5A 3LKTA 3PCNM 4WHOB 3MI1M 3O32A 3PCJA 3PCBA 2PCDM 3HHYA
chains in the Genus database with same CATH topology
2BV0B 3I4VA 1YKKA 4WHRF 1EO2B 3PCLA 3T67M 3PCDM 3MV6M 4WHPA 2BUZB 3HJ8A 1YKMA 3PCHA 4WHOD 3T63A 1YKLB 3HGIA 1EOBB 3PCJM 3MV4M 3LMXM 1YKNB 1DLQA 3HKPA 2BUVA 3PCKA 1YKOA 2BUMA 1YKKB 3LXVA 3HHXA 2BUWA 1EOCA 2BUUA 3N9TA 2BUYA 3PCCA 1S9AA 2XSUA 3PCGM 3PCEM 4ILTA 3T63M 4WHSA 3PCIA 4WHPB 3MFLA 2AZQA 1YKMB 3PCMA 3O5UA 3MI5M 3LKTM 3O6RA 1EOAA 2BOYA 3PCBM 3LXVM 2BUVB 1TMXA 3TH1A 1YKOB 2BUMB 3I4YA 4WHQA 2BUWB 3PCNA 1YKPA 3MI1A 1EOCB 2BUUB 3PCLM 3PCAA 2BUYB 2BUQA 5TD3A 3HJSA 4WHPD 2BUXA 2BUTA 4WHSB 3O6JA 3PCHM 1EO9A 3PCFA 2XSRA 3T67A 4WHRA 2BURA 1EOAB 2XSVA 3PCKM 1YKNA 3PCAM 4WHQB 4WHOA 3MV4A 3LMXA 1YKPB 2BUQB 3PCCM 4WHSD 2BV0A 3HJQA 3I51A 2BUXB 2PCDA 1DLTA 2BUTB 1DMHA 3PCIM 3MFLM 3PCFM 3PCMM 1EO2A 1EO9B 4WHRB 2BURB 1DLMA 3PCGA 3PCEA 2BUZA 3PCDA 4ILVA 1YKLA 3MV6A 1EOBA 3MI5A 3LKTA 3PCNM 4WHOB 3MI1M 3O32A 3PCJA 3PCBA 2PCDM 3HHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BV0 B;  3I4V A;  1YKK A;  4WHR F;  1EO2 B;  3PCL A;  3T67 M;  3PCD M;  3MV6 M;  4WHP A;  2BUZ B;  3HJ8 A;  1YKM A;  3PCH A;  4WHO D;  3T63 A;  1YKL B;  3HGI A;  1EOB B;  3PCJ M;  3MV4 M;  3LMX M;  1YKN B;  1DLQ A;  3HKP A;  2BUV A;  3PCK A;  1YKO A;  2BUM A;  1YKK B;  3LXV A;  3HHX A;  2BUW A;  1EOC A;  2BUU A;  3N9T A;  2BUY A;  3PCC A;  1S9A A;  2XSU A;  3PCG M;  3PCE M;  4ILT A;  3T63 M;  4WHS A;  3PCI A;  4WHP B;  3MFL A;  2AZQ A;  1YKM B;  3PCM A;  3O5U A;  3MI5 M;  3LKT M;  3O6R A;  1EOA A;  2BOY A;  3PCB M;  3LXV M;  2BUV B;  1TMX A;  3TH1 A;  1YKO B;  2BUM B;  3I4Y A;  4WHQ A;  2BUW B;  3PCN A;  1YKP A;  3MI1 A;  1EOC B;  2BUU B;  3PCL M;  3PCA A;  2BUY B;  2BUQ A;  5TD3 A;  3HJS A;  4WHP D;  2BUX A;  2BUT A;  4WHS B;  3O6J A;  3PCH M;  1EO9 A;  3PCF A;  2XSR A;  3T67 A;  4WHR A;  2BUR A;  1EOA B;  2XSV A;  3PCK M;  1YKN A;  3PCA M;  4WHQ B;  4WHO A;  3MV4 A;  3LMX A;  1YKP B;  2BUQ B;  3PCC M;  4WHS D;  2BV0 A;  3HJQ A;  3I51 A;  2BUX B;  2PCD A;  1DLT A;  2BUT B;  1DMH A;  3PCI M;  3MFL M;  3PCF M;  3PCM M;  1EO2 A;  1EO9 B;  4WHR B;  2BUR B;  1DLM A;  3PCG A;  3PCE A;  2BUZ A;  3PCD A;  4ILV A;  1YKL A;  3MV6 A;  1EOB A;  3MI5 A;  3LKT A;  3PCN M;  4WHO B;  3MI1 M;  3O32 A;  3PCJ A;  3PCB A;  2PCD M;  3HHY A; 
#chains in the Genus database with same CATH topology
 2BV0 B;  3I4V A;  1YKK A;  4WHR F;  1EO2 B;  3PCL A;  3T67 M;  3PCD M;  3MV6 M;  4WHP A;  2BUZ B;  3HJ8 A;  1YKM A;  3PCH A;  4WHO D;  3T63 A;  1YKL B;  3HGI A;  1EOB B;  3PCJ M;  3MV4 M;  3LMX M;  1YKN B;  1DLQ A;  3HKP A;  2BUV A;  3PCK A;  1YKO A;  2BUM A;  1YKK B;  3LXV A;  3HHX A;  2BUW A;  1EOC A;  2BUU A;  3N9T A;  2BUY A;  3PCC A;  1S9A A;  2XSU A;  3PCG M;  3PCE M;  4ILT A;  3T63 M;  4WHS A;  3PCI A;  4WHP B;  3MFL A;  2AZQ A;  1YKM B;  3PCM A;  3O5U A;  3MI5 M;  3LKT M;  3O6R A;  1EOA A;  2BOY A;  3PCB M;  3LXV M;  2BUV B;  1TMX A;  3TH1 A;  1YKO B;  2BUM B;  3I4Y A;  4WHQ A;  2BUW B;  3PCN A;  1YKP A;  3MI1 A;  1EOC B;  2BUU B;  3PCL M;  3PCA A;  2BUY B;  2BUQ A;  5TD3 A;  3HJS A;  4WHP D;  2BUX A;  2BUT A;  4WHS B;  3O6J A;  3PCH M;  1EO9 A;  3PCF A;  2XSR A;  3T67 A;  4WHR A;  2BUR A;  1EOA B;  2XSV A;  3PCK M;  1YKN A;  3PCA M;  4WHQ B;  4WHO A;  3MV4 A;  3LMX A;  1YKP B;  2BUQ B;  3PCC M;  4WHS D;  2BV0 A;  3HJQ A;  3I51 A;  2BUX B;  2PCD A;  1DLT A;  2BUT B;  1DMH A;  3PCI M;  3MFL M;  3PCF M;  3PCM M;  1EO2 A;  1EO9 B;  4WHR B;  2BUR B;  1DLM A;  3PCG A;  3PCE A;  2BUZ A;  3PCD A;  4ILV A;  1YKL A;  3MV6 A;  1EOB A;  3MI5 A;  3LKT A;  3PCN M;  4WHO B;  3MI1 M;  3O32 A;  3PCJ A;  3PCB A;  2PCD M;  3HHY A; 
#chains in the Genus database with same CATH homology
 2BV0 B;  3I4V A;  1YKK A;  4WHR F;  1EO2 B;  3PCL A;  3T67 M;  3PCD M;  3MV6 M;  4WHP A;  2BUZ B;  3HJ8 A;  1YKM A;  3PCH A;  4WHO D;  3T63 A;  1YKL B;  3HGI A;  1EOB B;  3PCJ M;  3MV4 M;  3LMX M;  1YKN B;  1DLQ A;  3HKP A;  2BUV A;  3PCK A;  1YKO A;  2BUM A;  1YKK B;  3LXV A;  3HHX A;  2BUW A;  1EOC A;  2BUU A;  3N9T A;  2BUY A;  3PCC A;  1S9A A;  2XSU A;  3PCG M;  3PCE M;  4ILT A;  3T63 M;  4WHS A;  3PCI A;  4WHP B;  3MFL A;  2AZQ A;  1YKM B;  3PCM A;  3O5U A;  3MI5 M;  3LKT M;  3O6R A;  1EOA A;  2BOY A;  3PCB M;  3LXV M;  2BUV B;  1TMX A;  3TH1 A;  1YKO B;  2BUM B;  3I4Y A;  4WHQ A;  2BUW B;  3PCN A;  1YKP A;  3MI1 A;  1EOC B;  2BUU B;  3PCL M;  3PCA A;  2BUY B;  2BUQ A;  5TD3 A;  3HJS A;  4WHP D;  2BUX A;  2BUT A;  4WHS B;  3O6J A;  3PCH M;  1EO9 A;  3PCF A;  2XSR A;  3T67 A;  4WHR A;  2BUR A;  1EOA B;  2XSV A;  3PCK M;  1YKN A;  3PCA M;  4WHQ B;  4WHO A;  3MV4 A;  3LMX A;  1YKP B;  2BUQ B;  3PCC M;  4WHS D;  2BV0 A;  3HJQ A;  3I51 A;  2BUX B;  2PCD A;  1DLT A;  2BUT B;  1DMH A;  3PCI M;  3MFL M;  3PCF M;  3PCM M;  1EO2 A;  1EO9 B;  4WHR B;  2BUR B;  1DLM A;  3PCG A;  3PCE A;  2BUZ A;  3PCD A;  4ILV A;  1YKL A;  3MV6 A;  1EOB A;  3MI5 A;  3LKT A;  3PCN M;  4WHO B;  3MI1 M;  3O32 A;  3PCJ A;  3PCB A;  2PCD M;  3HHY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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