3MFLM

Axial ligand swapping in double mutant maintains intradiol-cleavage chemistry in protocatechuate 3,4-dioxygenase
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
238
structure length
238
Chain Sequence
PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFNNGGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPHPWRNGPNDWRPAHIYFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFENC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Axial Ligand Swapping In Double Mutant Maintains Intradiol-cleavage Chemistry in Protocatechuate 3,4-Dioxygenase
rcsb
molecule tags Oxidoreductase
source organism Pseudomonas putida
molecule keywords Protocatechuate 3,4-dioxygenase alpha chain
total genus 56
structure length 238
sequence length 238
chains with identical sequence N, O
ec nomenclature ec 1.13.11.3: Protocatechuate 3,4-dioxygenase.
pdb deposition date 2010-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00775 Dioxygenase_C Dioxygenase
M PF12391 PCDO_beta_N Protocatechuate 3,4-dioxygenase beta subunit N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.130.10 Mainly Beta Sandwich Protocatechuate 3,4-Dioxygenase, subunit A Aromatic compound dioxygenase 3mflM00
3PCHA 3PCCM 4WHPB 3MI5A 2BUUA 3MV4A 3PCLA 2BUUB 2BUXA 3PCMM 3PCFM 3LXVA 2BUXB 3HJQA 3MFLA 3PCKM 4WHSD 3O6RA 1YKLA 1DLTA 2BUVA 1YKLB 2BUVB 1DMHA 5TD3A 4ILVA 1EOAA 3PCBM 2AZQA 2BUWA 4WHRF 3PCIA 1EOAB 3I4VA 3TH1A 3PCEM 2BUWB 3I51A 3PCGM 4WHRA 3LXVM 3PCAM 3HJSA 3T67M 3HHXA 2BUYA 4WHPD 1DLQA 1YKPA 2BUYB 3MV6A 3HJ8A 4WHPA 3PCIM 1YKPB 3PCJM 1EOCA 3MI1M 1YKKA 4WHQA 3PCDA 1YKNA 3T63M 3LKTM 1EOCB 2BUQA 1YKKB 3PCHM 4WHQB 1YKNB 3HKPA 3MI5M 2BUQB 1TMXA 3MV4M 4WHOA 3PCNA 2BUMA 2PCDA 3PCLM 2BUZA 2BUTA 4WHOB 3PCCA 2BUMB 2BUZB 2BUTB 1YKMA 3MFLM 4WHRB 3I4YA 1YKMB 3PCMA 2BURA 3PCFA 3PCKA 2BURB 3PCDM 3LMXA 1EO2A 1EOBA 2BV0A 3PCBA 1EO2B 1EOBB 2BV0B 3O6JA 1YKOA 4WHSA 3PCEA 3O32A 2BOYA 3O5UA 1DLMA 1YKOB 4WHSB 3PCGA 2XSRA 3HHYA 1EO9A 2XSUA 3N9TA 4ILTA 1EO9B 3PCAA 3T67A 3MV6M 1S9AA 3LMXM 3HGIA 4WHOD 2XSVA 3PCJA 3MI1A 3T63A 3LKTA 3PCNM 2PCDM
chains in the Genus database with same CATH superfamily
3PCHA 3PCCM 4WHPB 3MI5A 2BUUA 3MV4A 3PCLA 2BUUB 2BUXA 3PCMM 3PCFM 3LXVA 2BUXB 3HJQA 3MFLA 3PCKM 4WHSD 3O6RA 1YKLA 1DLTA 2BUVA 1YKLB 2BUVB 1DMHA 5TD3A 4ILVA 1EOAA 3PCBM 2AZQA 2BUWA 4WHRF 3PCIA 1EOAB 3I4VA 3TH1A 3PCEM 2BUWB 3I51A 3PCGM 4WHRA 3LXVM 3PCAM 3HJSA 3T67M 3HHXA 2BUYA 4WHPD 1DLQA 1YKPA 2BUYB 3MV6A 3HJ8A 4WHPA 3PCIM 1YKPB 3PCJM 1EOCA 3MI1M 1YKKA 4WHQA 3PCDA 1YKNA 3T63M 3LKTM 1EOCB 2BUQA 1YKKB 3PCHM 4WHQB 1YKNB 3HKPA 3MI5M 2BUQB 1TMXA 3MV4M 4WHOA 3PCNA 2BUMA 2PCDA 3PCLM 2BUZA 2BUTA 4WHOB 3PCCA 2BUMB 2BUZB 2BUTB 1YKMA 3MFLM 4WHRB 3I4YA 1YKMB 3PCMA 2BURA 3PCFA 3PCKA 2BURB 3PCDM 3LMXA 1EO2A 1EOBA 2BV0A 3PCBA 1EO2B 1EOBB 2BV0B 3O6JA 1YKOA 4WHSA 3PCEA 3O32A 2BOYA 3O5UA 1DLMA 1YKOB 4WHSB 3PCGA 2XSRA 3HHYA 1EO9A 2XSUA 3N9TA 4ILTA 1EO9B 3PCAA 3T67A 3MV6M 1S9AA 3LMXM 3HGIA 4WHOD 2XSVA 3PCJA 3MI1A 3T63A 3LKTA 3PCNM 2PCDM
chains in the Genus database with same CATH topology
3PCHA 3PCCM 4WHPB 3MI5A 2BUUA 3MV4A 3PCLA 2BUUB 2BUXA 3PCMM 3PCFM 3LXVA 2BUXB 3HJQA 3MFLA 3PCKM 4WHSD 3O6RA 1YKLA 1DLTA 2BUVA 1YKLB 2BUVB 1DMHA 5TD3A 4ILVA 1EOAA 3PCBM 2AZQA 2BUWA 4WHRF 3PCIA 1EOAB 3I4VA 3TH1A 3PCEM 2BUWB 3I51A 3PCGM 4WHRA 3LXVM 3PCAM 3HJSA 3T67M 3HHXA 2BUYA 4WHPD 1DLQA 1YKPA 2BUYB 3MV6A 3HJ8A 4WHPA 3PCIM 1YKPB 3PCJM 1EOCA 3MI1M 1YKKA 4WHQA 3PCDA 1YKNA 3T63M 3LKTM 1EOCB 2BUQA 1YKKB 3PCHM 4WHQB 1YKNB 3HKPA 3MI5M 2BUQB 1TMXA 3MV4M 4WHOA 3PCNA 2BUMA 2PCDA 3PCLM 2BUZA 2BUTA 4WHOB 3PCCA 2BUMB 2BUZB 2BUTB 1YKMA 3MFLM 4WHRB 3I4YA 1YKMB 3PCMA 2BURA 3PCFA 3PCKA 2BURB 3PCDM 3LMXA 1EO2A 1EOBA 2BV0A 3PCBA 1EO2B 1EOBB 2BV0B 3O6JA 1YKOA 4WHSA 3PCEA 3O32A 2BOYA 3O5UA 1DLMA 1YKOB 4WHSB 3PCGA 2XSRA 3HHYA 1EO9A 2XSUA 3N9TA 4ILTA 1EO9B 3PCAA 3T67A 3MV6M 1S9AA 3LMXM 3HGIA 4WHOD 2XSVA 3PCJA 3MI1A 3T63A 3LKTA 3PCNM 2PCDM
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PCH A;  3PCC M;  4WHP B;  3MI5 A;  2BUU A;  3MV4 A;  3PCL A;  2BUU B;  2BUX A;  3PCM M;  3PCF M;  3LXV A;  2BUX B;  3HJQ A;  3MFL A;  3PCK M;  4WHS D;  3O6R A;  1YKL A;  1DLT A;  2BUV A;  1YKL B;  2BUV B;  1DMH A;  5TD3 A;  4ILV A;  1EOA A;  3PCB M;  2AZQ A;  2BUW A;  4WHR F;  3PCI A;  1EOA B;  3I4V A;  3TH1 A;  3PCE M;  2BUW B;  3I51 A;  3PCG M;  4WHR A;  3LXV M;  3PCA M;  3HJS A;  3T67 M;  3HHX A;  2BUY A;  4WHP D;  1DLQ A;  1YKP A;  2BUY B;  3MV6 A;  3HJ8 A;  4WHP A;  3PCI M;  1YKP B;  3PCJ M;  1EOC A;  3MI1 M;  1YKK A;  4WHQ A;  3PCD A;  1YKN A;  3T63 M;  3LKT M;  1EOC B;  2BUQ A;  1YKK B;  3PCH M;  4WHQ B;  1YKN B;  3HKP A;  3MI5 M;  2BUQ B;  1TMX A;  3MV4 M;  4WHO A;  3PCN A;  2BUM A;  2PCD A;  3PCL M;  2BUZ A;  2BUT A;  4WHO B;  3PCC A;  2BUM B;  2BUZ B;  2BUT B;  1YKM A;  3MFL M;  4WHR B;  3I4Y A;  1YKM B;  3PCM A;  2BUR A;  3PCF A;  3PCK A;  2BUR B;  3PCD M;  3LMX A;  1EO2 A;  1EOB A;  2BV0 A;  3PCB A;  1EO2 B;  1EOB B;  2BV0 B;  3O6J A;  1YKO A;  4WHS A;  3PCE A;  3O32 A;  2BOY A;  3O5U A;  1DLM A;  1YKO B;  4WHS B;  3PCG A;  2XSR A;  3HHY A;  1EO9 A;  2XSU A;  3N9T A;  4ILT A;  1EO9 B;  3PCA A;  3T67 A;  3MV6 M;  1S9A A;  3LMX M;  3HGI A;  4WHO D;  2XSV A;  3PCJ A;  3MI1 A;  3T63 A;  3LKT A;  3PCN M;  2PCD M; 
#chains in the Genus database with same CATH topology
 3PCH A;  3PCC M;  4WHP B;  3MI5 A;  2BUU A;  3MV4 A;  3PCL A;  2BUU B;  2BUX A;  3PCM M;  3PCF M;  3LXV A;  2BUX B;  3HJQ A;  3MFL A;  3PCK M;  4WHS D;  3O6R A;  1YKL A;  1DLT A;  2BUV A;  1YKL B;  2BUV B;  1DMH A;  5TD3 A;  4ILV A;  1EOA A;  3PCB M;  2AZQ A;  2BUW A;  4WHR F;  3PCI A;  1EOA B;  3I4V A;  3TH1 A;  3PCE M;  2BUW B;  3I51 A;  3PCG M;  4WHR A;  3LXV M;  3PCA M;  3HJS A;  3T67 M;  3HHX A;  2BUY A;  4WHP D;  1DLQ A;  1YKP A;  2BUY B;  3MV6 A;  3HJ8 A;  4WHP A;  3PCI M;  1YKP B;  3PCJ M;  1EOC A;  3MI1 M;  1YKK A;  4WHQ A;  3PCD A;  1YKN A;  3T63 M;  3LKT M;  1EOC B;  2BUQ A;  1YKK B;  3PCH M;  4WHQ B;  1YKN B;  3HKP A;  3MI5 M;  2BUQ B;  1TMX A;  3MV4 M;  4WHO A;  3PCN A;  2BUM A;  2PCD A;  3PCL M;  2BUZ A;  2BUT A;  4WHO B;  3PCC A;  2BUM B;  2BUZ B;  2BUT B;  1YKM A;  3MFL M;  4WHR B;  3I4Y A;  1YKM B;  3PCM A;  2BUR A;  3PCF A;  3PCK A;  2BUR B;  3PCD M;  3LMX A;  1EO2 A;  1EOB A;  2BV0 A;  3PCB A;  1EO2 B;  1EOB B;  2BV0 B;  3O6J A;  1YKO A;  4WHS A;  3PCE A;  3O32 A;  2BOY A;  3O5U A;  1DLM A;  1YKO B;  4WHS B;  3PCG A;  2XSR A;  3HHY A;  1EO9 A;  2XSU A;  3N9T A;  4ILT A;  1EO9 B;  3PCA A;  3T67 A;  3MV6 M;  1S9A A;  3LMX M;  3HGI A;  4WHO D;  2XSV A;  3PCJ A;  3MI1 A;  3T63 A;  3LKT A;  3PCN M;  2PCD M; 
#chains in the Genus database with same CATH homology
 3PCH A;  3PCC M;  4WHP B;  3MI5 A;  2BUU A;  3MV4 A;  3PCL A;  2BUU B;  2BUX A;  3PCM M;  3PCF M;  3LXV A;  2BUX B;  3HJQ A;  3MFL A;  3PCK M;  4WHS D;  3O6R A;  1YKL A;  1DLT A;  2BUV A;  1YKL B;  2BUV B;  1DMH A;  5TD3 A;  4ILV A;  1EOA A;  3PCB M;  2AZQ A;  2BUW A;  4WHR F;  3PCI A;  1EOA B;  3I4V A;  3TH1 A;  3PCE M;  2BUW B;  3I51 A;  3PCG M;  4WHR A;  3LXV M;  3PCA M;  3HJS A;  3T67 M;  3HHX A;  2BUY A;  4WHP D;  1DLQ A;  1YKP A;  2BUY B;  3MV6 A;  3HJ8 A;  4WHP A;  3PCI M;  1YKP B;  3PCJ M;  1EOC A;  3MI1 M;  1YKK A;  4WHQ A;  3PCD A;  1YKN A;  3T63 M;  3LKT M;  1EOC B;  2BUQ A;  1YKK B;  3PCH M;  4WHQ B;  1YKN B;  3HKP A;  3MI5 M;  2BUQ B;  1TMX A;  3MV4 M;  4WHO A;  3PCN A;  2BUM A;  2PCD A;  3PCL M;  2BUZ A;  2BUT A;  4WHO B;  3PCC A;  2BUM B;  2BUZ B;  2BUT B;  1YKM A;  3MFL M;  4WHR B;  3I4Y A;  1YKM B;  3PCM A;  2BUR A;  3PCF A;  3PCK A;  2BUR B;  3PCD M;  3LMX A;  1EO2 A;  1EOB A;  2BV0 A;  3PCB A;  1EO2 B;  1EOB B;  2BV0 B;  3O6J A;  1YKO A;  4WHS A;  3PCE A;  3O32 A;  2BOY A;  3O5U A;  1DLM A;  1YKO B;  4WHS B;  3PCG A;  2XSR A;  3HHY A;  1EO9 A;  2XSU A;  3N9T A;  4ILT A;  1EO9 B;  3PCA A;  3T67 A;  3MV6 M;  1S9A A;  3LMX M;  3HGI A;  4WHO D;  2XSV A;  3PCJ A;  3MI1 A;  3T63 A;  3LKT A;  3PCN M;  2PCD M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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