3MXAA

Molecular basis of engineered meganuclease targeting of the endogenous human rag1 locus
Total Genus 97
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
343
structure length
301
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQINPNQSSKFKHRLRLTFYVTQKTQRRWFLDKLVDEIGVGYVRDSGSVSQYVLSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLSNKEFLLYLAGFVDSDGSIIAQIKPRQSNKFKHQLSLTFAVTQKTQRRWFLDKLVDEIGVGYVYDSGSVSDYRLSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLDS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords scV3V2(G19S)
total genus 97
structure length 301
sequence length 343
ec nomenclature
pdb deposition date 2010-05-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3mxaA02
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3mxaA01
2XE0B 3OORA 2VS8A 4AADA 3UVFA 1DFAA 2XE0A 2VBNA 1EF0A 4LOXA 5A0MB 3C0XA 5A77A 2O7MA 1M5XA 5A78A 4UN9A 4AAGA 5AKNA 1JVAA 4AAFA 4EFJA 2VBLB 4UN8G 5E63A 2VBLA 1U0CA 4UT0A 3E54A 2VBNB 1BP7A 2VS7A 2AB5A 4Z1ZA 3C0WA 1DQ3A 2CW8A 1P8KZ 1T9JA 2CW7A 3MIPA 2VBJB 5A72A 5E5OA 2VBJA 2FLDA 4Z1XA 4UN8A 4D6NA 1AF5A 5AKFA 5E67A 1T9IA 4UN7G 3HYIA 4YITA 3QQYA 2EX5A 3EH8A 1B24A 4AABA 5E5SA 3MX9A 3MXBA 1LWTA 1G9YA 4LQ0A 3HYJA 3KO2A 5A74A 3R7PA 1R7MA 4D6OA 4YISA 1G9ZA 2VBOA 4AQXA 4UNCA 4UN7A 4YHXA 1VDEA 3MISA 2DCHX 4AAEA 1UM2A 4UNBA 1LWSA 5A0WA 2I3PA 1MOWA 5A0MA 3OOLA 3MXBB 5AKMA 1U0DA 2I3QA 4UNAA 4UN9G 2VBOB 4Z20A 3FD2A 4AQUA 1N3EA 2QOJZ 1N3FA 5AK9A 3MXAA
chains in the Genus database with same CATH superfamily
2XE0B 3OORA 2VS8A 4AADA 3UVFA 1DFAA 2XE0A 2VBNA 1EF0A 4LOXA 5A0MB 3C0XA 5A77A 2O7MA 1M5XA 5A78A 4UN9A 4AAGA 5AKNA 1JVAA 4AAFA 4EFJA 2VBLB 4UN8G 5E63A 2VBLA 1U0CA 4UT0A 3E54A 2VBNB 1BP7A 2VS7A 2AB5A 4Z1ZA 3C0WA 1DQ3A 2CW8A 1P8KZ 2F4LA 1T9JA 2CW7A 3MIPA 2VBJB 5A72A 5E5OA 2VBJA 2FLDA 4Z1XA 4UN8A 4D6NA 1AF5A 5AKFA 5E67A 1T9IA 4UN7G 3HYIA 4YITA 3QQYA 2EX5A 3EH8A 1B24A 4AABA 4KZSA 5E5SA 3MX9A 3MXBA 1LWTA 1G9YA 4LQ0A 3HYJA 3KO2A 5A74A 3R7PA 1R7MA 4D6OA 4YISA 1G9ZA 2VBOA 4AQXA 4UNCA 4UN7A 4YHXA 1VDEA 3MISA 2DCHX 4AAEA 1UM2A 4UNBA 1LWSA 5A0WA 2I3PA 1MOWA 5A0MA 3OOLA 3MXBB 5AKMA 1U0DA 2I3QA 4UNAA 4UN9G 2VBOB 4Z20A 3FD2A 4AQUA 1N3EA 2QOJZ 1N3FA 5AK9A 3MXAA
chains in the Genus database with same CATH topology
2XE0B 3OORA 2VS8A 4AADA 3UVFA 1DFAA 2XE0A 2VBNA 1EF0A 4LOXA 5A0MB 3C0XA 5A77A 2O7MA 1M5XA 5A78A 4UN9A 4AAGA 5AKNA 1JVAA 4AAFA 4EFJA 2VBLB 4UN8G 5E63A 2VBLA 1U0CA 4UT0A 3E54A 2VBNB 1BP7A 2VS7A 2AB5A 4Z1ZA 3C0WA 1DQ3A 2CW8A 1P8KZ 1T9JA 2CW7A 3MIPA 2VBJB 5A72A 5E5OA 2VBJA 2FLDA 4Z1XA 4UN8A 4D6NA 1AF5A 5AKFA 5E67A 1T9IA 4UN7G 3HYIA 4YITA 3QQYA 2EX5A 3EH8A 1B24A 4AABA 5E5SA 3MX9A 3MXBA 1LWTA 1G9YA 4LQ0A 3HYJA 3KO2A 5A74A 3R7PA 1R7MA 4D6OA 4YISA 1G9ZA 2VBOA 4AQXA 4UNCA 4UN7A 4YHXA 1VDEA 3MISA 2DCHX 4AAEA 1UM2A 4UNBA 1LWSA 5A0WA 2I3PA 1MOWA 5A0MA 3OOLA 3MXBB 5AKMA 1U0DA 2I3QA 4UNAA 4UN9G 2VBOB 4Z20A 3FD2A 4AQUA 1N3EA 2QOJZ 1N3FA 5AK9A 3MXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XE0 B;  3OOR A;  2VS8 A;  4AAD A;  3UVF A;  1DFA A;  2XE0 A;  2VBN A;  1EF0 A;  4LOX A;  5A0M B;  3C0X A;  5A77 A;  2O7M A;  1M5X A;  5A78 A;  4UN9 A;  4AAG A;  5AKN A;  1JVA A;  4AAF A;  4EFJ A;  2VBL B;  4UN8 G;  5E63 A;  2VBL A;  1U0C A;  4UT0 A;  3E54 A;  2VBN B;  1BP7 A;  2VS7 A;  2AB5 A;  4Z1Z A;  3C0W A;  1DQ3 A;  2CW8 A;  1P8K Z;  1T9J A;  2CW7 A;  3MIP A;  2VBJ B;  5A72 A;  5E5O A;  2VBJ A;  2FLD A;  4Z1X A;  4UN8 A;  4D6N A;  1AF5 A;  5AKF A;  5E67 A;  1T9I A;  4UN7 G;  3HYI A;  4YIT A;  3QQY A;  2EX5 A;  3EH8 A;  1B24 A;  4AAB A;  5E5S A;  3MX9 A;  3MXB A;  1LWT A;  1G9Y A;  4LQ0 A;  3HYJ A;  3KO2 A;  5A74 A;  3R7P A;  1R7M A;  4D6O A;  4YIS A;  1G9Z A;  2VBO A;  4AQX A;  4UNC A;  4UN7 A;  4YHX A;  1VDE A;  3MIS A;  2DCH X;  4AAE A;  1UM2 A;  4UNB A;  1LWS A;  5A0W A;  2I3P A;  1MOW A;  5A0M A;  3OOL A;  3MXB B;  5AKM A;  1U0D A;  2I3Q A;  4UNA A;  4UN9 G;  2VBO B;  4Z20 A;  3FD2 A;  4AQU A;  1N3E A;  2QOJ Z;  1N3F A;  5AK9 A;  3MXA A; 
#chains in the Genus database with same CATH topology
 2XE0 B;  3OOR A;  2VS8 A;  4AAD A;  3UVF A;  1DFA A;  2XE0 A;  2VBN A;  1EF0 A;  4LOX A;  5A0M B;  3C0X A;  5A77 A;  2O7M A;  1M5X A;  5A78 A;  4UN9 A;  4AAG A;  5AKN A;  1JVA A;  4AAF A;  4EFJ A;  2VBL B;  4UN8 G;  5E63 A;  2VBL A;  1U0C A;  4UT0 A;  3E54 A;  2VBN B;  1BP7 A;  2VS7 A;  2AB5 A;  4Z1Z A;  3C0W A;  1DQ3 A;  2CW8 A;  1P8K Z;  2F4L A;  1T9J A;  2CW7 A;  3MIP A;  2VBJ B;  5A72 A;  5E5O A;  2VBJ A;  2FLD A;  4Z1X A;  4UN8 A;  4D6N A;  1AF5 A;  5AKF A;  5E67 A;  1T9I A;  4UN7 G;  3HYI A;  4YIT A;  3QQY A;  2EX5 A;  3EH8 A;  1B24 A;  4AAB A;  4KZS A;  5E5S A;  3MX9 A;  3MXB A;  1LWT A;  1G9Y A;  4LQ0 A;  3HYJ A;  3KO2 A;  5A74 A;  3R7P A;  1R7M A;  4D6O A;  4YIS A;  1G9Z A;  2VBO A;  4AQX A;  4UNC A;  4UN7 A;  4YHX A;  1VDE A;  3MIS A;  2DCH X;  4AAE A;  1UM2 A;  4UNB A;  1LWS A;  5A0W A;  2I3P A;  1MOW A;  5A0M A;  3OOL A;  3MXB B;  5AKM A;  1U0D A;  2I3Q A;  4UNA A;  4UN9 G;  2VBO B;  4Z20 A;  3FD2 A;  4AQU A;  1N3E A;  2QOJ Z;  1N3F A;  5AK9 A;  3MXA A; 
#chains in the Genus database with same CATH homology
 2XE0 B;  3OOR A;  2VS8 A;  4AAD A;  3UVF A;  1DFA A;  2XE0 A;  2VBN A;  1EF0 A;  4LOX A;  5A0M B;  3C0X A;  5A77 A;  2O7M A;  1M5X A;  5A78 A;  4UN9 A;  4AAG A;  5AKN A;  1JVA A;  4AAF A;  4EFJ A;  2VBL B;  4UN8 G;  5E63 A;  2VBL A;  1U0C A;  4UT0 A;  3E54 A;  2VBN B;  1BP7 A;  2VS7 A;  2AB5 A;  4Z1Z A;  3C0W A;  1DQ3 A;  2CW8 A;  1P8K Z;  1T9J A;  2CW7 A;  3MIP A;  2VBJ B;  5A72 A;  5E5O A;  2VBJ A;  2FLD A;  4Z1X A;  4UN8 A;  4D6N A;  1AF5 A;  5AKF A;  5E67 A;  1T9I A;  4UN7 G;  3HYI A;  4YIT A;  3QQY A;  2EX5 A;  3EH8 A;  1B24 A;  4AAB A;  5E5S A;  3MX9 A;  3MXB A;  1LWT A;  1G9Y A;  4LQ0 A;  3HYJ A;  3KO2 A;  5A74 A;  3R7P A;  1R7M A;  4D6O A;  4YIS A;  1G9Z A;  2VBO A;  4AQX A;  4UNC A;  4UN7 A;  4YHX A;  1VDE A;  3MIS A;  2DCH X;  4AAE A;  1UM2 A;  4UNB A;  1LWS A;  5A0W A;  2I3P A;  1MOW A;  5A0M A;  3OOL A;  3MXB B;  5AKM A;  1U0D A;  2I3Q A;  4UNA A;  4UN9 G;  2VBO B;  4Z20 A;  3FD2 A;  4AQU A;  1N3E A;  2QOJ Z;  1N3F A;  5AK9 A;  3MXA A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...