3OOLA

I-scei complexed with c/g+4 dna substrate
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
223
structure length
223
Chain Sequence
NIKKNQVMNLGPNSKLLKEYKSQLIELNIEQFEAGIGLILGDAYIRSRDEGKTYCMQFEWKNKAYMDHVCLLYDQWVLSPPHKKERVNHLGNLVITWGAQTFKHQAFNKLANLFIVNNKKTIPNNLVENYLTPMSLAYWFMDDGGKWDYNKNSTNKSIVLNTQSFTFEEVEYLVKGLRNKFQLNCYVKINKNKPIIYIDSMSYLIFYNLIKPYLIPQMMYKLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Evolution of I-SceI Homing Endonucleases with Increased DNA Recognition Site Specificity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
molecule keywords Intron encoded endonuclease I-SceI
total genus 66
structure length 223
sequence length 223
ec nomenclature ec 3.1.-.-:
pdb deposition date 2010-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03161 LAGLIDADG_2 LAGLIDADG DNA endonuclease family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3oolA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3oolA02
3HYJA 4AQXA 1AF5A 1JVAA 1UM2A 5AKFA 1U0DA 2XE0A 1B24A 2VBJA 1MOWA 5A0MA 4YITA 1G9ZA 4UN9G 1DQ3A 4AADA 4UN8G 1U0CA 2VBOA 1EF0A 3QQYA 5A0WA 4UN7A 2VBNB 4Z1XA 2O7MA 4YHXA 3KO2A 1BP7A 2VBLB 5A78A 5A77A 3MX9A 5AK9A 3MXBA 2AB5A 3C0WA 4AQUA 2CW7A 5A72A 4LOXA 3MISA 4AAGA 5E67A 2QOJZ 4D6OA 4UNBA 1T9IA 4Z20A 3EH8A 5A74A 4YISA 1G9YA 4UNAA 3HYIA 3OORA 4LQ0A 4EFJA 4UN9A 4Z1ZA 4UN8A 3UVFA 2VBNA 2I3QA 2EX5A 2CW8A 2VS7A 2XE0B 2VBLA 2VBJB 3C0XA 5A0MB 1M5XA 3MXAA 4UN7G 2DCHX 1VDEA 4UT0A 2VBOB 1LWSA 1N3EA 5AKMA 2VS8A 1P8KZ 4AAFA 3E54A 1DFAA 5E63A 4AAEA 5E5OA 4UNCA 4D6NA 3FD2A 5E5SA 3OOLA 5AKNA 1N3FA 1T9JA 3MXBB 1R7MA 4AABA 2FLDA 2I3PA 1LWTA 3R7PA 3MIPA
chains in the Genus database with same CATH superfamily
3HYJA 4AQXA 1AF5A 1JVAA 1UM2A 5AKFA 1U0DA 2XE0A 1B24A 2VBJA 1MOWA 5A0MA 4YITA 1G9ZA 4UN9G 1DQ3A 4AADA 4UN8G 1U0CA 2VBOA 1EF0A 3QQYA 4KZSA 5A0WA 4UN7A 2VBNB 2F4LA 4Z1XA 2O7MA 4YHXA 3KO2A 1BP7A 2VBLB 5A78A 5A77A 3MX9A 5AK9A 3MXBA 2AB5A 3C0WA 4AQUA 2CW7A 5A72A 4LOXA 3MISA 4AAGA 5E67A 2QOJZ 4D6OA 4UNBA 1T9IA 4Z20A 3EH8A 5A74A 4YISA 1G9YA 4UNAA 3HYIA 3OORA 4LQ0A 4EFJA 4UN9A 4Z1ZA 4UN8A 3UVFA 2VBNA 2I3QA 2EX5A 2CW8A 2VS7A 2XE0B 2VBLA 2VBJB 3C0XA 5A0MB 1M5XA 3MXAA 4UN7G 2DCHX 1VDEA 4UT0A 2VBOB 1LWSA 1N3EA 5AKMA 2VS8A 1P8KZ 4AAFA 3E54A 1DFAA 5E63A 4AAEA 5E5OA 4UNCA 4D6NA 3FD2A 5E5SA 3OOLA 5AKNA 1N3FA 1T9JA 3MXBB 1R7MA 4AABA 2FLDA 2I3PA 1LWTA 3R7PA 3MIPA
chains in the Genus database with same CATH topology
3HYJA 4AQXA 1AF5A 1JVAA 1UM2A 5AKFA 1U0DA 2XE0A 1B24A 2VBJA 1MOWA 5A0MA 4YITA 1G9ZA 4UN9G 1DQ3A 4AADA 4UN8G 1U0CA 2VBOA 1EF0A 3QQYA 5A0WA 4UN7A 2VBNB 4Z1XA 2O7MA 4YHXA 3KO2A 1BP7A 2VBLB 5A78A 5A77A 3MX9A 5AK9A 3MXBA 2AB5A 3C0WA 4AQUA 2CW7A 5A72A 4LOXA 3MISA 4AAGA 5E67A 2QOJZ 4D6OA 4UNBA 1T9IA 4Z20A 3EH8A 5A74A 4YISA 1G9YA 4UNAA 3HYIA 3OORA 4LQ0A 4EFJA 4UN9A 4Z1ZA 4UN8A 3UVFA 2VBNA 2I3QA 2EX5A 2CW8A 2VS7A 2XE0B 2VBLA 2VBJB 3C0XA 5A0MB 1M5XA 3MXAA 4UN7G 2DCHX 1VDEA 4UT0A 2VBOB 1LWSA 1N3EA 5AKMA 2VS8A 1P8KZ 4AAFA 3E54A 1DFAA 5E63A 4AAEA 5E5OA 4UNCA 4D6NA 3FD2A 5E5SA 3OOLA 5AKNA 1N3FA 1T9JA 3MXBB 1R7MA 4AABA 2FLDA 2I3PA 1LWTA 3R7PA 3MIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HYJ A;  4AQX A;  1AF5 A;  1JVA A;  1UM2 A;  5AKF A;  1U0D A;  2XE0 A;  1B24 A;  2VBJ A;  1MOW A;  5A0M A;  4YIT A;  1G9Z A;  4UN9 G;  1DQ3 A;  4AAD A;  4UN8 G;  1U0C A;  2VBO A;  1EF0 A;  3QQY A;  5A0W A;  4UN7 A;  2VBN B;  4Z1X A;  2O7M A;  4YHX A;  3KO2 A;  1BP7 A;  2VBL B;  5A78 A;  5A77 A;  3MX9 A;  5AK9 A;  3MXB A;  2AB5 A;  3C0W A;  4AQU A;  2CW7 A;  5A72 A;  4LOX A;  3MIS A;  4AAG A;  5E67 A;  2QOJ Z;  4D6O A;  4UNB A;  1T9I A;  4Z20 A;  3EH8 A;  5A74 A;  4YIS A;  1G9Y A;  4UNA A;  3HYI A;  3OOR A;  4LQ0 A;  4EFJ A;  4UN9 A;  4Z1Z A;  4UN8 A;  3UVF A;  2VBN A;  2I3Q A;  2EX5 A;  2CW8 A;  2VS7 A;  2XE0 B;  2VBL A;  2VBJ B;  3C0X A;  5A0M B;  1M5X A;  3MXA A;  4UN7 G;  2DCH X;  1VDE A;  4UT0 A;  2VBO B;  1LWS A;  1N3E A;  5AKM A;  2VS8 A;  1P8K Z;  4AAF A;  3E54 A;  1DFA A;  5E63 A;  4AAE A;  5E5O A;  4UNC A;  4D6N A;  3FD2 A;  5E5S A;  3OOL A;  5AKN A;  1N3F A;  1T9J A;  3MXB B;  1R7M A;  4AAB A;  2FLD A;  2I3P A;  1LWT A;  3R7P A;  3MIP A; 
#chains in the Genus database with same CATH topology
 3HYJ A;  4AQX A;  1AF5 A;  1JVA A;  1UM2 A;  5AKF A;  1U0D A;  2XE0 A;  1B24 A;  2VBJ A;  1MOW A;  5A0M A;  4YIT A;  1G9Z A;  4UN9 G;  1DQ3 A;  4AAD A;  4UN8 G;  1U0C A;  2VBO A;  1EF0 A;  3QQY A;  4KZS A;  5A0W A;  4UN7 A;  2VBN B;  2F4L A;  4Z1X A;  2O7M A;  4YHX A;  3KO2 A;  1BP7 A;  2VBL B;  5A78 A;  5A77 A;  3MX9 A;  5AK9 A;  3MXB A;  2AB5 A;  3C0W A;  4AQU A;  2CW7 A;  5A72 A;  4LOX A;  3MIS A;  4AAG A;  5E67 A;  2QOJ Z;  4D6O A;  4UNB A;  1T9I A;  4Z20 A;  3EH8 A;  5A74 A;  4YIS A;  1G9Y A;  4UNA A;  3HYI A;  3OOR A;  4LQ0 A;  4EFJ A;  4UN9 A;  4Z1Z A;  4UN8 A;  3UVF A;  2VBN A;  2I3Q A;  2EX5 A;  2CW8 A;  2VS7 A;  2XE0 B;  2VBL A;  2VBJ B;  3C0X A;  5A0M B;  1M5X A;  3MXA A;  4UN7 G;  2DCH X;  1VDE A;  4UT0 A;  2VBO B;  1LWS A;  1N3E A;  5AKM A;  2VS8 A;  1P8K Z;  4AAF A;  3E54 A;  1DFA A;  5E63 A;  4AAE A;  5E5O A;  4UNC A;  4D6N A;  3FD2 A;  5E5S A;  3OOL A;  5AKN A;  1N3F A;  1T9J A;  3MXB B;  1R7M A;  4AAB A;  2FLD A;  2I3P A;  1LWT A;  3R7P A;  3MIP A; 
#chains in the Genus database with same CATH homology
 3HYJ A;  4AQX A;  1AF5 A;  1JVA A;  1UM2 A;  5AKF A;  1U0D A;  2XE0 A;  1B24 A;  2VBJ A;  1MOW A;  5A0M A;  4YIT A;  1G9Z A;  4UN9 G;  1DQ3 A;  4AAD A;  4UN8 G;  1U0C A;  2VBO A;  1EF0 A;  3QQY A;  5A0W A;  4UN7 A;  2VBN B;  4Z1X A;  2O7M A;  4YHX A;  3KO2 A;  1BP7 A;  2VBL B;  5A78 A;  5A77 A;  3MX9 A;  5AK9 A;  3MXB A;  2AB5 A;  3C0W A;  4AQU A;  2CW7 A;  5A72 A;  4LOX A;  3MIS A;  4AAG A;  5E67 A;  2QOJ Z;  4D6O A;  4UNB A;  1T9I A;  4Z20 A;  3EH8 A;  5A74 A;  4YIS A;  1G9Y A;  4UNA A;  3HYI A;  3OOR A;  4LQ0 A;  4EFJ A;  4UN9 A;  4Z1Z A;  4UN8 A;  3UVF A;  2VBN A;  2I3Q A;  2EX5 A;  2CW8 A;  2VS7 A;  2XE0 B;  2VBL A;  2VBJ B;  3C0X A;  5A0M B;  1M5X A;  3MXA A;  4UN7 G;  2DCH X;  1VDE A;  4UT0 A;  2VBO B;  1LWS A;  1N3E A;  5AKM A;  2VS8 A;  1P8K Z;  4AAF A;  3E54 A;  1DFA A;  5E63 A;  4AAE A;  5E5O A;  4UNC A;  4D6N A;  3FD2 A;  5E5S A;  3OOL A;  5AKN A;  1N3F A;  1T9J A;  3MXB B;  1R7M A;  4AAB A;  2FLD A;  2I3P A;  1LWT A;  3R7P A;  3MIP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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