3QQYA

Crystal structure of a novel laglidadg homing endonuclease, i-onui (from ophiostoma novo-ulmi subsp. americana)
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
302
structure length
299
Chain Sequence
AYMSRRESINPWILTGFADAEGSFLLRIRNNNKSSVGYSTELGFQITLHNKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLKVIIDHFEKYPLITQKLGDYMLFKQAFCVMENKEHLKINGIKELVRIKAKLNWGLTDELKKAFPEIISSLINKNIPNFKWLAGFTSGEGCFFVNLIKSKSKLGVQVQLVFSITQHIKDKNLMNSLITYLGCGYIKEKNKSEFSWLDFVVTKFSDINDKIIPVFQENTLIGVKLEDFEDWCKVAKLIEEKKHLTESGLDEIKKIKLNMNKGRVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Tapping natural reservoirs of homing endonucleases for targeted gene modification.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Ophiostoma novo-ulmi subsp. americana
molecule keywords Ribosomal protein 3/homing endonuclease-like protein fusion
total genus 89
structure length 299
sequence length 302
ec nomenclature
pdb deposition date 2011-02-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3qqyA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 3qqyA02
1UM2A 4D6OA 3MX9A 1AF5A 5E5SA 3KO2A 5A0WA 4UT0A 2I3PA 2VS7A 2XE0B 3R7PA 1G9ZA 1T9IA 3OOLA 5A0MA 4AAEA 4UNAA 1N3FA 2VS8A 4UN9A 1M5XA 2DCHX 1LWTA 1U0CA 2I3QA 2CW8A 2EX5A 2VBJA 3MISA 3OORA 4Z1XA 4LOXA 3HYJA 4EFJA 3FD2A 5A0MB 2VBNB 1BP7A 1DQ3A 2VBNA 1VDEA 4YITA 4UN7G 1R7MA 5A74A 4UN7A 3E54A 4Z1ZA 3HYIA 2QOJZ 1JVAA 2VBLB 1G9YA 5E5OA 2VBLA 2VBOB 2VBOA 4Z20A 3UVFA 1U0DA 4UNCA 2VBJB 4AABA 5E67A 3MXAA 4AAGA 5A72A 4D6NA 1B24A 4YHXA 5AKFA 5AKMA 1EF0A 1MOWA 1T9JA 5AKNA 4AAFA 4UNBA 4AQXA 2FLDA 5AK9A 1DFAA 3C0XA 3MXBB 1N3EA 5A77A 3MXBA 3QQYA 2O7MA 4YISA 4UN8G 5E63A 1P8KZ 5A78A 4UN8A 2XE0A 4AQUA 2CW7A 3MIPA 3C0WA 3EH8A 4LQ0A 4UN9G 4AADA 1LWSA 2AB5A
chains in the Genus database with same CATH superfamily
1UM2A 4D6OA 3MX9A 1AF5A 5E5SA 3KO2A 5A0WA 4UT0A 2I3PA 2VS7A 2XE0B 3R7PA 1G9ZA 1T9IA 3OOLA 5A0MA 4AAEA 4UNAA 1N3FA 2VS8A 4UN9A 1M5XA 2DCHX 1LWTA 1U0CA 2I3QA 2CW8A 2EX5A 2VBJA 3MISA 3OORA 4Z1XA 4LOXA 3HYJA 4EFJA 3FD2A 5A0MB 2VBNB 1BP7A 1DQ3A 2VBNA 1VDEA 4YITA 4UN7G 1R7MA 5A74A 4UN7A 3E54A 4Z1ZA 3HYIA 2QOJZ 1JVAA 2VBLB 1G9YA 5E5OA 2VBLA 2VBOB 2VBOA 4Z20A 3UVFA 1U0DA 4UNCA 2VBJB 4AABA 5E67A 3MXAA 4AAGA 5A72A 4D6NA 1B24A 4YHXA 5AKFA 5AKMA 1EF0A 1MOWA 1T9JA 5AKNA 2F4LA 4AAFA 4UNBA 4KZSA 4AQXA 2FLDA 5AK9A 1DFAA 3C0XA 3MXBB 1N3EA 5A77A 3MXBA 3QQYA 2O7MA 4YISA 4UN8G 5E63A 1P8KZ 5A78A 4UN8A 2XE0A 4AQUA 2CW7A 3MIPA 3C0WA 3EH8A 4LQ0A 4UN9G 4AADA 1LWSA 2AB5A
chains in the Genus database with same CATH topology
1UM2A 4D6OA 3MX9A 1AF5A 5E5SA 3KO2A 5A0WA 4UT0A 2I3PA 2VS7A 2XE0B 3R7PA 1G9ZA 1T9IA 3OOLA 5A0MA 4AAEA 4UNAA 1N3FA 2VS8A 4UN9A 1M5XA 2DCHX 1LWTA 1U0CA 2I3QA 2CW8A 2EX5A 2VBJA 3MISA 3OORA 4Z1XA 4LOXA 3HYJA 4EFJA 3FD2A 5A0MB 2VBNB 1BP7A 1DQ3A 2VBNA 1VDEA 4YITA 4UN7G 1R7MA 5A74A 4UN7A 3E54A 4Z1ZA 3HYIA 2QOJZ 1JVAA 2VBLB 1G9YA 5E5OA 2VBLA 2VBOB 2VBOA 4Z20A 3UVFA 1U0DA 4UNCA 2VBJB 4AABA 5E67A 3MXAA 4AAGA 5A72A 4D6NA 1B24A 4YHXA 5AKFA 5AKMA 1EF0A 1MOWA 1T9JA 5AKNA 4AAFA 4UNBA 4AQXA 2FLDA 5AK9A 1DFAA 3C0XA 3MXBB 1N3EA 5A77A 3MXBA 3QQYA 2O7MA 4YISA 4UN8G 5E63A 1P8KZ 5A78A 4UN8A 2XE0A 4AQUA 2CW7A 3MIPA 3C0WA 3EH8A 4LQ0A 4UN9G 4AADA 1LWSA 2AB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UM2 A;  4D6O A;  3MX9 A;  1AF5 A;  5E5S A;  3KO2 A;  5A0W A;  4UT0 A;  2I3P A;  2VS7 A;  2XE0 B;  3R7P A;  1G9Z A;  1T9I A;  3OOL A;  5A0M A;  4AAE A;  4UNA A;  1N3F A;  2VS8 A;  4UN9 A;  1M5X A;  2DCH X;  1LWT A;  1U0C A;  2I3Q A;  2CW8 A;  2EX5 A;  2VBJ A;  3MIS A;  3OOR A;  4Z1X A;  4LOX A;  3HYJ A;  4EFJ A;  3FD2 A;  5A0M B;  2VBN B;  1BP7 A;  1DQ3 A;  2VBN A;  1VDE A;  4YIT A;  4UN7 G;  1R7M A;  5A74 A;  4UN7 A;  3E54 A;  4Z1Z A;  3HYI A;  2QOJ Z;  1JVA A;  2VBL B;  1G9Y A;  5E5O A;  2VBL A;  2VBO B;  2VBO A;  4Z20 A;  3UVF A;  1U0D A;  4UNC A;  2VBJ B;  4AAB A;  5E67 A;  3MXA A;  4AAG A;  5A72 A;  4D6N A;  1B24 A;  4YHX A;  5AKF A;  5AKM A;  1EF0 A;  1MOW A;  1T9J A;  5AKN A;  4AAF A;  4UNB A;  4AQX A;  2FLD A;  5AK9 A;  1DFA A;  3C0X A;  3MXB B;  1N3E A;  5A77 A;  3MXB A;  3QQY A;  2O7M A;  4YIS A;  4UN8 G;  5E63 A;  1P8K Z;  5A78 A;  4UN8 A;  2XE0 A;  4AQU A;  2CW7 A;  3MIP A;  3C0W A;  3EH8 A;  4LQ0 A;  4UN9 G;  4AAD A;  1LWS A;  2AB5 A; 
#chains in the Genus database with same CATH topology
 1UM2 A;  4D6O A;  3MX9 A;  1AF5 A;  5E5S A;  3KO2 A;  5A0W A;  4UT0 A;  2I3P A;  2VS7 A;  2XE0 B;  3R7P A;  1G9Z A;  1T9I A;  3OOL A;  5A0M A;  4AAE A;  4UNA A;  1N3F A;  2VS8 A;  4UN9 A;  1M5X A;  2DCH X;  1LWT A;  1U0C A;  2I3Q A;  2CW8 A;  2EX5 A;  2VBJ A;  3MIS A;  3OOR A;  4Z1X A;  4LOX A;  3HYJ A;  4EFJ A;  3FD2 A;  5A0M B;  2VBN B;  1BP7 A;  1DQ3 A;  2VBN A;  1VDE A;  4YIT A;  4UN7 G;  1R7M A;  5A74 A;  4UN7 A;  3E54 A;  4Z1Z A;  3HYI A;  2QOJ Z;  1JVA A;  2VBL B;  1G9Y A;  5E5O A;  2VBL A;  2VBO B;  2VBO A;  4Z20 A;  3UVF A;  1U0D A;  4UNC A;  2VBJ B;  4AAB A;  5E67 A;  3MXA A;  4AAG A;  5A72 A;  4D6N A;  1B24 A;  4YHX A;  5AKF A;  5AKM A;  1EF0 A;  1MOW A;  1T9J A;  5AKN A;  2F4L A;  4AAF A;  4UNB A;  4KZS A;  4AQX A;  2FLD A;  5AK9 A;  1DFA A;  3C0X A;  3MXB B;  1N3E A;  5A77 A;  3MXB A;  3QQY A;  2O7M A;  4YIS A;  4UN8 G;  5E63 A;  1P8K Z;  5A78 A;  4UN8 A;  2XE0 A;  4AQU A;  2CW7 A;  3MIP A;  3C0W A;  3EH8 A;  4LQ0 A;  4UN9 G;  4AAD A;  1LWS A;  2AB5 A; 
#chains in the Genus database with same CATH homology
 1UM2 A;  4D6O A;  3MX9 A;  1AF5 A;  5E5S A;  3KO2 A;  5A0W A;  4UT0 A;  2I3P A;  2VS7 A;  2XE0 B;  3R7P A;  1G9Z A;  1T9I A;  3OOL A;  5A0M A;  4AAE A;  4UNA A;  1N3F A;  2VS8 A;  4UN9 A;  1M5X A;  2DCH X;  1LWT A;  1U0C A;  2I3Q A;  2CW8 A;  2EX5 A;  2VBJ A;  3MIS A;  3OOR A;  4Z1X A;  4LOX A;  3HYJ A;  4EFJ A;  3FD2 A;  5A0M B;  2VBN B;  1BP7 A;  1DQ3 A;  2VBN A;  1VDE A;  4YIT A;  4UN7 G;  1R7M A;  5A74 A;  4UN7 A;  3E54 A;  4Z1Z A;  3HYI A;  2QOJ Z;  1JVA A;  2VBL B;  1G9Y A;  5E5O A;  2VBL A;  2VBO B;  2VBO A;  4Z20 A;  3UVF A;  1U0D A;  4UNC A;  2VBJ B;  4AAB A;  5E67 A;  3MXA A;  4AAG A;  5A72 A;  4D6N A;  1B24 A;  4YHX A;  5AKF A;  5AKM A;  1EF0 A;  1MOW A;  1T9J A;  5AKN A;  4AAF A;  4UNB A;  4AQX A;  2FLD A;  5AK9 A;  1DFA A;  3C0X A;  3MXB B;  1N3E A;  5A77 A;  3MXB A;  3QQY A;  2O7M A;  4YIS A;  4UN8 G;  5E63 A;  1P8K Z;  5A78 A;  4UN8 A;  2XE0 A;  4AQU A;  2CW7 A;  3MIP A;  3C0W A;  3EH8 A;  4LQ0 A;  4UN9 G;  4AAD A;  1LWS A;  2AB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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