4AABA

Crystal structure of the mutant d75n i-crei in complex with its wild- type target (the four central bases, 2nn region, are composed by gtac from 5' to 3')
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 50
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aabA00
3EH8A 1BP7A 4UNCA 2VBLA 4UN9G 4UN7G 3MXAA 4AQXA 2FLDA 3R7PA 4YHXA 4UNBA 1JVAA 3HYIA 3C0XA 2CW8A 5AKMA 4UN9A 4UN7A 4AQUA 3E54A 4YISA 1LWSA 2VBJA 1EF0A 4AABA 5A77A 2DCHX 3MX9A 1G9YA 1AF5A 4UN8G 3KO2A 2VBOB 2CW7A 5A0MA 3QQYA 5A0MB 2VBNA 2VBNB 5AKNA 4AADA 4AAEA 1VDEA 1R7MA 4UN8A 3C0WA 5A72A 4EFJA 1DFAA 3MIPA 2VS7A 3OOLA 5A74A 2EX5A 1M5XA 4D6NA 4YITA 1T9IA 2I3PA 2O7MA 1U0CA 5A78A 4AAFA 4UT0A 2VS8A 2VBOA 1N3FA 4Z1XA 3FD2A 5E63A 2I3QA 5AK9A 1N3EA 1DQ3A 4LOXA 1LWTA 4UNAA 4D6OA 2AB5A 5E5SA 4Z20A 1G9ZA 1UM2A 3OORA 1P8KZ 1U0DA 5A0WA 2VBLB 4Z1ZA 5E67A 1MOWA 4LQ0A 1B24A 3MXBA 5AKFA 3MISA 1T9JA 3MXBB 4AAGA 3HYJA 2QOJZ 5E5OA 2XE0A 2XE0B 2VBJB 3UVFA
chains in the Genus database with same CATH superfamily
3EH8A 1BP7A 4UNCA 2VBLA 4UN9G 4UN7G 3MXAA 4AQXA 2FLDA 3R7PA 4YHXA 4UNBA 1JVAA 3HYIA 3C0XA 2CW8A 5AKMA 4UN9A 4UN7A 4AQUA 3E54A 4YISA 1LWSA 2VBJA 1EF0A 4AABA 5A77A 2DCHX 3MX9A 1G9YA 1AF5A 4UN8G 3KO2A 2VBOB 2CW7A 5A0MA 3QQYA 5A0MB 2VBNA 2VBNB 5AKNA 4AADA 4AAEA 1VDEA 1R7MA 4UN8A 3C0WA 5A72A 4EFJA 1DFAA 3MIPA 2VS7A 3OOLA 5A74A 2EX5A 1M5XA 4D6NA 4YITA 1T9IA 2I3PA 4KZSA 2O7MA 1U0CA 5A78A 4AAFA 4UT0A 2VS8A 2VBOA 1N3FA 4Z1XA 3FD2A 5E63A 2I3QA 5AK9A 1N3EA 1DQ3A 4LOXA 1LWTA 4UNAA 4D6OA 2AB5A 5E5SA 4Z20A 2F4LA 1G9ZA 1UM2A 3OORA 1P8KZ 1U0DA 5A0WA 2VBLB 4Z1ZA 5E67A 1MOWA 4LQ0A 1B24A 3MXBA 5AKFA 3MISA 1T9JA 3MXBB 4AAGA 3HYJA 2QOJZ 5E5OA 2XE0A 2XE0B 2VBJB 3UVFA
chains in the Genus database with same CATH topology
3EH8A 1BP7A 4UNCA 2VBLA 4UN9G 4UN7G 3MXAA 4AQXA 2FLDA 3R7PA 4YHXA 4UNBA 1JVAA 3HYIA 3C0XA 2CW8A 5AKMA 4UN9A 4UN7A 4AQUA 3E54A 4YISA 1LWSA 2VBJA 1EF0A 4AABA 5A77A 2DCHX 3MX9A 1G9YA 1AF5A 4UN8G 3KO2A 2VBOB 2CW7A 5A0MA 3QQYA 5A0MB 2VBNA 2VBNB 5AKNA 4AADA 4AAEA 1VDEA 1R7MA 4UN8A 3C0WA 5A72A 4EFJA 1DFAA 3MIPA 2VS7A 3OOLA 5A74A 2EX5A 1M5XA 4D6NA 4YITA 1T9IA 2I3PA 2O7MA 1U0CA 5A78A 4AAFA 4UT0A 2VS8A 2VBOA 1N3FA 4Z1XA 3FD2A 5E63A 2I3QA 5AK9A 1N3EA 1DQ3A 4LOXA 1LWTA 4UNAA 4D6OA 2AB5A 5E5SA 4Z20A 1G9ZA 1UM2A 3OORA 1P8KZ 1U0DA 5A0WA 2VBLB 4Z1ZA 5E67A 1MOWA 4LQ0A 1B24A 3MXBA 5AKFA 3MISA 1T9JA 3MXBB 4AAGA 3HYJA 2QOJZ 5E5OA 2XE0A 2XE0B 2VBJB 3UVFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EH8 A;  1BP7 A;  4UNC A;  2VBL A;  4UN9 G;  4UN7 G;  3MXA A;  4AQX A;  2FLD A;  3R7P A;  4YHX A;  4UNB A;  1JVA A;  3HYI A;  3C0X A;  2CW8 A;  5AKM A;  4UN9 A;  4UN7 A;  4AQU A;  3E54 A;  4YIS A;  1LWS A;  2VBJ A;  1EF0 A;  4AAB A;  5A77 A;  2DCH X;  3MX9 A;  1G9Y A;  1AF5 A;  4UN8 G;  3KO2 A;  2VBO B;  2CW7 A;  5A0M A;  3QQY A;  5A0M B;  2VBN A;  2VBN B;  5AKN A;  4AAD A;  4AAE A;  1VDE A;  1R7M A;  4UN8 A;  3C0W A;  5A72 A;  4EFJ A;  1DFA A;  3MIP A;  2VS7 A;  3OOL A;  5A74 A;  2EX5 A;  1M5X A;  4D6N A;  4YIT A;  1T9I A;  2I3P A;  2O7M A;  1U0C A;  5A78 A;  4AAF A;  4UT0 A;  2VS8 A;  2VBO A;  1N3F A;  4Z1X A;  3FD2 A;  5E63 A;  2I3Q A;  5AK9 A;  1N3E A;  1DQ3 A;  4LOX A;  1LWT A;  4UNA A;  4D6O A;  2AB5 A;  5E5S A;  4Z20 A;  1G9Z A;  1UM2 A;  3OOR A;  1P8K Z;  1U0D A;  5A0W A;  2VBL B;  4Z1Z A;  5E67 A;  1MOW A;  4LQ0 A;  1B24 A;  3MXB A;  5AKF A;  3MIS A;  1T9J A;  3MXB B;  4AAG A;  3HYJ A;  2QOJ Z;  5E5O A;  2XE0 A;  2XE0 B;  2VBJ B;  3UVF A; 
#chains in the Genus database with same CATH topology
 3EH8 A;  1BP7 A;  4UNC A;  2VBL A;  4UN9 G;  4UN7 G;  3MXA A;  4AQX A;  2FLD A;  3R7P A;  4YHX A;  4UNB A;  1JVA A;  3HYI A;  3C0X A;  2CW8 A;  5AKM A;  4UN9 A;  4UN7 A;  4AQU A;  3E54 A;  4YIS A;  1LWS A;  2VBJ A;  1EF0 A;  4AAB A;  5A77 A;  2DCH X;  3MX9 A;  1G9Y A;  1AF5 A;  4UN8 G;  3KO2 A;  2VBO B;  2CW7 A;  5A0M A;  3QQY A;  5A0M B;  2VBN A;  2VBN B;  5AKN A;  4AAD A;  4AAE A;  1VDE A;  1R7M A;  4UN8 A;  3C0W A;  5A72 A;  4EFJ A;  1DFA A;  3MIP A;  2VS7 A;  3OOL A;  5A74 A;  2EX5 A;  1M5X A;  4D6N A;  4YIT A;  1T9I A;  2I3P A;  4KZS A;  2O7M A;  1U0C A;  5A78 A;  4AAF A;  4UT0 A;  2VS8 A;  2VBO A;  1N3F A;  4Z1X A;  3FD2 A;  5E63 A;  2I3Q A;  5AK9 A;  1N3E A;  1DQ3 A;  4LOX A;  1LWT A;  4UNA A;  4D6O A;  2AB5 A;  5E5S A;  4Z20 A;  2F4L A;  1G9Z A;  1UM2 A;  3OOR A;  1P8K Z;  1U0D A;  5A0W A;  2VBL B;  4Z1Z A;  5E67 A;  1MOW A;  4LQ0 A;  1B24 A;  3MXB A;  5AKF A;  3MIS A;  1T9J A;  3MXB B;  4AAG A;  3HYJ A;  2QOJ Z;  5E5O A;  2XE0 A;  2XE0 B;  2VBJ B;  3UVF A; 
#chains in the Genus database with same CATH homology
 3EH8 A;  1BP7 A;  4UNC A;  2VBL A;  4UN9 G;  4UN7 G;  3MXA A;  4AQX A;  2FLD A;  3R7P A;  4YHX A;  4UNB A;  1JVA A;  3HYI A;  3C0X A;  2CW8 A;  5AKM A;  4UN9 A;  4UN7 A;  4AQU A;  3E54 A;  4YIS A;  1LWS A;  2VBJ A;  1EF0 A;  4AAB A;  5A77 A;  2DCH X;  3MX9 A;  1G9Y A;  1AF5 A;  4UN8 G;  3KO2 A;  2VBO B;  2CW7 A;  5A0M A;  3QQY A;  5A0M B;  2VBN A;  2VBN B;  5AKN A;  4AAD A;  4AAE A;  1VDE A;  1R7M A;  4UN8 A;  3C0W A;  5A72 A;  4EFJ A;  1DFA A;  3MIP A;  2VS7 A;  3OOL A;  5A74 A;  2EX5 A;  1M5X A;  4D6N A;  4YIT A;  1T9I A;  2I3P A;  2O7M A;  1U0C A;  5A78 A;  4AAF A;  4UT0 A;  2VS8 A;  2VBO A;  1N3F A;  4Z1X A;  3FD2 A;  5E63 A;  2I3Q A;  5AK9 A;  1N3E A;  1DQ3 A;  4LOX A;  1LWT A;  4UNA A;  4D6O A;  2AB5 A;  5E5S A;  4Z20 A;  1G9Z A;  1UM2 A;  3OOR A;  1P8K Z;  1U0D A;  5A0W A;  2VBL B;  4Z1Z A;  5E67 A;  1MOW A;  4LQ0 A;  1B24 A;  3MXB A;  5AKF A;  3MIS A;  1T9J A;  3MXB B;  4AAG A;  3HYJ A;  2QOJ Z;  5E5O A;  2XE0 A;  2XE0 B;  2VBJ B;  3UVF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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