4AADA

Crystal structure of the mutant d75n i-crei in complex with its wild- type target in absence of metal ions at the active site (the four central bases, 2nn region, are composed by gtac from 5' to 3')
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
151
structure length
151
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 45
structure length 151
sequence length 151
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aadA00
2VBOB 2O7MA 1BP7A 4D6OA 5AKNA 2CW7A 2EX5A 3HYJA 1U0CA 5A78A 1N3EA 4D6NA 5AK9A 5E63A 3E54A 3KO2A 3C0XA 1G9ZA 4Z1ZA 1U0DA 2CW8A 2QOJZ 2VS7A 4UN8A 4YITA 1UM2A 3MXBB 3UVFA 2FLDA 4EFJA 3R7PA 2XE0A 4UNCA 5AKMA 4YISA 1DQ3A 4UN7G 4UN9A 5A77A 5AKFA 5A74A 3MISA 2XE0B 3OORA 4AABA 1T9JA 5A0WA 1M5XA 4AAFA 2VBJA 5A0MA 1JVAA 3HYIA 2I3QA 5E5OA 1LWTA 4LQ0A 4Z1XA 2VBLA 1P8KZ 4UN9G 1LWSA 4UNBA 1G9YA 4AAGA 1T9IA 3MXAA 1EF0A 2I3PA 3C0WA 5E67A 4LOXA 1DFAA 3MX9A 4AADA 2DCHX 1R7MA 2AB5A 2VBJB 5A72A 4UN8G 5A0MB 1MOWA 1VDEA 1AF5A 1N3FA 4AQXA 3FD2A 2VBLB 5E5SA 1B24A 4UNAA 4UN7A 4AQUA 3EH8A 3MIPA 4YHXA 2VBNA 3OOLA 3QQYA 4UT0A 2VBOA 4Z20A 4AAEA 3MXBA 2VS8A 2VBNB
chains in the Genus database with same CATH superfamily
2VBOB 2O7MA 1BP7A 4D6OA 5AKNA 2CW7A 2EX5A 3HYJA 1U0CA 5A78A 1N3EA 4D6NA 5AK9A 5E63A 3E54A 3KO2A 3C0XA 1G9ZA 4Z1ZA 1U0DA 2CW8A 2QOJZ 2VS7A 4UN8A 4YITA 1UM2A 3MXBB 3UVFA 2FLDA 4EFJA 3R7PA 2XE0A 4UNCA 5AKMA 4YISA 1DQ3A 4UN7G 4UN9A 5A77A 5AKFA 5A74A 3MISA 2XE0B 3OORA 2F4LA 4AABA 1T9JA 5A0WA 1M5XA 4AAFA 2VBJA 5A0MA 1JVAA 3HYIA 2I3QA 5E5OA 1LWTA 4LQ0A 4Z1XA 2VBLA 1P8KZ 4UN9G 1LWSA 4UNBA 1G9YA 4AAGA 1T9IA 3MXAA 4KZSA 1EF0A 2I3PA 3C0WA 5E67A 4LOXA 1DFAA 3MX9A 4AADA 2DCHX 1R7MA 2AB5A 2VBJB 5A72A 4UN8G 5A0MB 1MOWA 1VDEA 1AF5A 1N3FA 4AQXA 3FD2A 2VBLB 5E5SA 1B24A 4UNAA 4UN7A 4AQUA 3EH8A 3MIPA 4YHXA 2VBNA 3OOLA 3QQYA 4UT0A 2VBOA 4Z20A 4AAEA 3MXBA 2VS8A 2VBNB
chains in the Genus database with same CATH topology
2VBOB 2O7MA 1BP7A 4D6OA 5AKNA 2CW7A 2EX5A 3HYJA 1U0CA 5A78A 1N3EA 4D6NA 5AK9A 5E63A 3E54A 3KO2A 3C0XA 1G9ZA 4Z1ZA 1U0DA 2CW8A 2QOJZ 2VS7A 4UN8A 4YITA 1UM2A 3MXBB 3UVFA 2FLDA 4EFJA 3R7PA 2XE0A 4UNCA 5AKMA 4YISA 1DQ3A 4UN7G 4UN9A 5A77A 5AKFA 5A74A 3MISA 2XE0B 3OORA 4AABA 1T9JA 5A0WA 1M5XA 4AAFA 2VBJA 5A0MA 1JVAA 3HYIA 2I3QA 5E5OA 1LWTA 4LQ0A 4Z1XA 2VBLA 1P8KZ 4UN9G 1LWSA 4UNBA 1G9YA 4AAGA 1T9IA 3MXAA 1EF0A 2I3PA 3C0WA 5E67A 4LOXA 1DFAA 3MX9A 4AADA 2DCHX 1R7MA 2AB5A 2VBJB 5A72A 4UN8G 5A0MB 1MOWA 1VDEA 1AF5A 1N3FA 4AQXA 3FD2A 2VBLB 5E5SA 1B24A 4UNAA 4UN7A 4AQUA 3EH8A 3MIPA 4YHXA 2VBNA 3OOLA 3QQYA 4UT0A 2VBOA 4Z20A 4AAEA 3MXBA 2VS8A 2VBNB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VBO B;  2O7M A;  1BP7 A;  4D6O A;  5AKN A;  2CW7 A;  2EX5 A;  3HYJ A;  1U0C A;  5A78 A;  1N3E A;  4D6N A;  5AK9 A;  5E63 A;  3E54 A;  3KO2 A;  3C0X A;  1G9Z A;  4Z1Z A;  1U0D A;  2CW8 A;  2QOJ Z;  2VS7 A;  4UN8 A;  4YIT A;  1UM2 A;  3MXB B;  3UVF A;  2FLD A;  4EFJ A;  3R7P A;  2XE0 A;  4UNC A;  5AKM A;  4YIS A;  1DQ3 A;  4UN7 G;  4UN9 A;  5A77 A;  5AKF A;  5A74 A;  3MIS A;  2XE0 B;  3OOR A;  4AAB A;  1T9J A;  5A0W A;  1M5X A;  4AAF A;  2VBJ A;  5A0M A;  1JVA A;  3HYI A;  2I3Q A;  5E5O A;  1LWT A;  4LQ0 A;  4Z1X A;  2VBL A;  1P8K Z;  4UN9 G;  1LWS A;  4UNB A;  1G9Y A;  4AAG A;  1T9I A;  3MXA A;  1EF0 A;  2I3P A;  3C0W A;  5E67 A;  4LOX A;  1DFA A;  3MX9 A;  4AAD A;  2DCH X;  1R7M A;  2AB5 A;  2VBJ B;  5A72 A;  4UN8 G;  5A0M B;  1MOW A;  1VDE A;  1AF5 A;  1N3F A;  4AQX A;  3FD2 A;  2VBL B;  5E5S A;  1B24 A;  4UNA A;  4UN7 A;  4AQU A;  3EH8 A;  3MIP A;  4YHX A;  2VBN A;  3OOL A;  3QQY A;  4UT0 A;  2VBO A;  4Z20 A;  4AAE A;  3MXB A;  2VS8 A;  2VBN B; 
#chains in the Genus database with same CATH topology
 2VBO B;  2O7M A;  1BP7 A;  4D6O A;  5AKN A;  2CW7 A;  2EX5 A;  3HYJ A;  1U0C A;  5A78 A;  1N3E A;  4D6N A;  5AK9 A;  5E63 A;  3E54 A;  3KO2 A;  3C0X A;  1G9Z A;  4Z1Z A;  1U0D A;  2CW8 A;  2QOJ Z;  2VS7 A;  4UN8 A;  4YIT A;  1UM2 A;  3MXB B;  3UVF A;  2FLD A;  4EFJ A;  3R7P A;  2XE0 A;  4UNC A;  5AKM A;  4YIS A;  1DQ3 A;  4UN7 G;  4UN9 A;  5A77 A;  5AKF A;  5A74 A;  3MIS A;  2XE0 B;  3OOR A;  2F4L A;  4AAB A;  1T9J A;  5A0W A;  1M5X A;  4AAF A;  2VBJ A;  5A0M A;  1JVA A;  3HYI A;  2I3Q A;  5E5O A;  1LWT A;  4LQ0 A;  4Z1X A;  2VBL A;  1P8K Z;  4UN9 G;  1LWS A;  4UNB A;  1G9Y A;  4AAG A;  1T9I A;  3MXA A;  4KZS A;  1EF0 A;  2I3P A;  3C0W A;  5E67 A;  4LOX A;  1DFA A;  3MX9 A;  4AAD A;  2DCH X;  1R7M A;  2AB5 A;  2VBJ B;  5A72 A;  4UN8 G;  5A0M B;  1MOW A;  1VDE A;  1AF5 A;  1N3F A;  4AQX A;  3FD2 A;  2VBL B;  5E5S A;  1B24 A;  4UNA A;  4UN7 A;  4AQU A;  3EH8 A;  3MIP A;  4YHX A;  2VBN A;  3OOL A;  3QQY A;  4UT0 A;  2VBO A;  4Z20 A;  4AAE A;  3MXB A;  2VS8 A;  2VBN B; 
#chains in the Genus database with same CATH homology
 2VBO B;  2O7M A;  1BP7 A;  4D6O A;  5AKN A;  2CW7 A;  2EX5 A;  3HYJ A;  1U0C A;  5A78 A;  1N3E A;  4D6N A;  5AK9 A;  5E63 A;  3E54 A;  3KO2 A;  3C0X A;  1G9Z A;  4Z1Z A;  1U0D A;  2CW8 A;  2QOJ Z;  2VS7 A;  4UN8 A;  4YIT A;  1UM2 A;  3MXB B;  3UVF A;  2FLD A;  4EFJ A;  3R7P A;  2XE0 A;  4UNC A;  5AKM A;  4YIS A;  1DQ3 A;  4UN7 G;  4UN9 A;  5A77 A;  5AKF A;  5A74 A;  3MIS A;  2XE0 B;  3OOR A;  4AAB A;  1T9J A;  5A0W A;  1M5X A;  4AAF A;  2VBJ A;  5A0M A;  1JVA A;  3HYI A;  2I3Q A;  5E5O A;  1LWT A;  4LQ0 A;  4Z1X A;  2VBL A;  1P8K Z;  4UN9 G;  1LWS A;  4UNB A;  1G9Y A;  4AAG A;  1T9I A;  3MXA A;  1EF0 A;  2I3P A;  3C0W A;  5E67 A;  4LOX A;  1DFA A;  3MX9 A;  4AAD A;  2DCH X;  1R7M A;  2AB5 A;  2VBJ B;  5A72 A;  4UN8 G;  5A0M B;  1MOW A;  1VDE A;  1AF5 A;  1N3F A;  4AQX A;  3FD2 A;  2VBL B;  5E5S A;  1B24 A;  4UNA A;  4UN7 A;  4AQU A;  3EH8 A;  3MIP A;  4YHX A;  2VBN A;  3OOL A;  3QQY A;  4UT0 A;  2VBO A;  4Z20 A;  4AAE A;  3MXB A;  2VS8 A;  2VBN B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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