4AAEA

Crystal structure of the mutant d75n i-crei in complex with an altered target (the four central bases, 2nn region, are composed by agcg from 5' to 3')
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 46
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aaeA00
2XE0A 1R7MA 1B24A 5AKNA 1T9JA 3R7PA 3C0XA 4UN9A 1N3FA 4UT0A 3FD2A 4D6OA 4UN7A 1UM2A 5E63A 1G9ZA 5A77A 2AB5A 5E67A 5AK9A 2I3PA 3E54A 4Z20A 2XE0B 5A0WA 2VS8A 5E5OA 3KO2A 4UN8A 3C0WA 2VBJA 3OOLA 1EF0A 4AQUA 4YITA 5A78A 3MXBA 3MX9A 3HYIA 3MXAA 5E5SA 1VDEA 5A0MA 3QQYA 3MIPA 2VBJB 1U0CA 4AAEA 1U0DA 4LQ0A 2VBOA 4AADA 3MXBB 2VBNA 4D6NA 4AQXA 4AAFA 1N3EA 4UNCA 2FLDA 5AKFA 4Z1ZA 3EH8A 3HYJA 5A0MB 4UN9G 1LWSA 2DCHX 2CW7A 3OORA 4UN7G 2VBOB 2VBNB 1AF5A 1JVAA 2O7MA 1G9YA 4AABA 1DQ3A 4EFJA 3MISA 2I3QA 2VBLA 4UN8G 4UNBA 4LOXA 1DFAA 1M5XA 4YISA 1MOWA 2VBLB 3UVFA 5A74A 5AKMA 1P8KZ 5A72A 2VS7A 1T9IA 4Z1XA 2CW8A 1BP7A 4UNAA 4YHXA 2EX5A 1LWTA 4AAGA 2QOJZ
chains in the Genus database with same CATH superfamily
2XE0A 1R7MA 1B24A 5AKNA 1T9JA 3R7PA 3C0XA 4UN9A 1N3FA 4UT0A 3FD2A 4D6OA 4UN7A 1UM2A 5E63A 1G9ZA 5A77A 2AB5A 5E67A 5AK9A 2I3PA 3E54A 4Z20A 2XE0B 5A0WA 2VS8A 5E5OA 3KO2A 4UN8A 3C0WA 2VBJA 3OOLA 1EF0A 4AQUA 4YITA 5A78A 3MXBA 3MX9A 3HYIA 3MXAA 5E5SA 1VDEA 5A0MA 3QQYA 3MIPA 2VBJB 1U0CA 4AAEA 1U0DA 4LQ0A 2VBOA 4AADA 3MXBB 2VBNA 4D6NA 4AQXA 4AAFA 1N3EA 4UNCA 2FLDA 5AKFA 4Z1ZA 3EH8A 3HYJA 5A0MB 4UN9G 1LWSA 2DCHX 2CW7A 3OORA 4UN7G 2VBOB 2VBNB 1AF5A 1JVAA 2O7MA 1G9YA 4AABA 1DQ3A 4EFJA 3MISA 2I3QA 2VBLA 4UN8G 4UNBA 4LOXA 1DFAA 1M5XA 4KZSA 2F4LA 4YISA 1MOWA 2VBLB 3UVFA 5A74A 5AKMA 1P8KZ 5A72A 2VS7A 1T9IA 4Z1XA 2CW8A 1BP7A 4UNAA 4YHXA 2EX5A 1LWTA 4AAGA 2QOJZ
chains in the Genus database with same CATH topology
2XE0A 1R7MA 1B24A 5AKNA 1T9JA 3R7PA 3C0XA 4UN9A 1N3FA 4UT0A 3FD2A 4D6OA 4UN7A 1UM2A 5E63A 1G9ZA 5A77A 2AB5A 5E67A 5AK9A 2I3PA 3E54A 4Z20A 2XE0B 5A0WA 2VS8A 5E5OA 3KO2A 4UN8A 3C0WA 2VBJA 3OOLA 1EF0A 4AQUA 4YITA 5A78A 3MXBA 3MX9A 3HYIA 3MXAA 5E5SA 1VDEA 5A0MA 3QQYA 3MIPA 2VBJB 1U0CA 4AAEA 1U0DA 4LQ0A 2VBOA 4AADA 3MXBB 2VBNA 4D6NA 4AQXA 4AAFA 1N3EA 4UNCA 2FLDA 5AKFA 4Z1ZA 3EH8A 3HYJA 5A0MB 4UN9G 1LWSA 2DCHX 2CW7A 3OORA 4UN7G 2VBOB 2VBNB 1AF5A 1JVAA 2O7MA 1G9YA 4AABA 1DQ3A 4EFJA 3MISA 2I3QA 2VBLA 4UN8G 4UNBA 4LOXA 1DFAA 1M5XA 4YISA 1MOWA 2VBLB 3UVFA 5A74A 5AKMA 1P8KZ 5A72A 2VS7A 1T9IA 4Z1XA 2CW8A 1BP7A 4UNAA 4YHXA 2EX5A 1LWTA 4AAGA 2QOJZ
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2XE0 A;  1R7M A;  1B24 A;  5AKN A;  1T9J A;  3R7P A;  3C0X A;  4UN9 A;  1N3F A;  4UT0 A;  3FD2 A;  4D6O A;  4UN7 A;  1UM2 A;  5E63 A;  1G9Z A;  5A77 A;  2AB5 A;  5E67 A;  5AK9 A;  2I3P A;  3E54 A;  4Z20 A;  2XE0 B;  5A0W A;  2VS8 A;  5E5O A;  3KO2 A;  4UN8 A;  3C0W A;  2VBJ A;  3OOL A;  1EF0 A;  4AQU A;  4YIT A;  5A78 A;  3MXB A;  3MX9 A;  3HYI A;  3MXA A;  5E5S A;  1VDE A;  5A0M A;  3QQY A;  3MIP A;  2VBJ B;  1U0C A;  4AAE A;  1U0D A;  4LQ0 A;  2VBO A;  4AAD A;  3MXB B;  2VBN A;  4D6N A;  4AQX A;  4AAF A;  1N3E A;  4UNC A;  2FLD A;  5AKF A;  4Z1Z A;  3EH8 A;  3HYJ A;  5A0M B;  4UN9 G;  1LWS A;  2DCH X;  2CW7 A;  3OOR A;  4UN7 G;  2VBO B;  2VBN B;  1AF5 A;  1JVA A;  2O7M A;  1G9Y A;  4AAB A;  1DQ3 A;  4EFJ A;  3MIS A;  2I3Q A;  2VBL A;  4UN8 G;  4UNB A;  4LOX A;  1DFA A;  1M5X A;  4YIS A;  1MOW A;  2VBL B;  3UVF A;  5A74 A;  5AKM A;  1P8K Z;  5A72 A;  2VS7 A;  1T9I A;  4Z1X A;  2CW8 A;  1BP7 A;  4UNA A;  4YHX A;  2EX5 A;  1LWT A;  4AAG A;  2QOJ Z; 
#chains in the Genus database with same CATH topology
 2XE0 A;  1R7M A;  1B24 A;  5AKN A;  1T9J A;  3R7P A;  3C0X A;  4UN9 A;  1N3F A;  4UT0 A;  3FD2 A;  4D6O A;  4UN7 A;  1UM2 A;  5E63 A;  1G9Z A;  5A77 A;  2AB5 A;  5E67 A;  5AK9 A;  2I3P A;  3E54 A;  4Z20 A;  2XE0 B;  5A0W A;  2VS8 A;  5E5O A;  3KO2 A;  4UN8 A;  3C0W A;  2VBJ A;  3OOL A;  1EF0 A;  4AQU A;  4YIT A;  5A78 A;  3MXB A;  3MX9 A;  3HYI A;  3MXA A;  5E5S A;  1VDE A;  5A0M A;  3QQY A;  3MIP A;  2VBJ B;  1U0C A;  4AAE A;  1U0D A;  4LQ0 A;  2VBO A;  4AAD A;  3MXB B;  2VBN A;  4D6N A;  4AQX A;  4AAF A;  1N3E A;  4UNC A;  2FLD A;  5AKF A;  4Z1Z A;  3EH8 A;  3HYJ A;  5A0M B;  4UN9 G;  1LWS A;  2DCH X;  2CW7 A;  3OOR A;  4UN7 G;  2VBO B;  2VBN B;  1AF5 A;  1JVA A;  2O7M A;  1G9Y A;  4AAB A;  1DQ3 A;  4EFJ A;  3MIS A;  2I3Q A;  2VBL A;  4UN8 G;  4UNB A;  4LOX A;  1DFA A;  1M5X A;  4KZS A;  2F4L A;  4YIS A;  1MOW A;  2VBL B;  3UVF A;  5A74 A;  5AKM A;  1P8K Z;  5A72 A;  2VS7 A;  1T9I A;  4Z1X A;  2CW8 A;  1BP7 A;  4UNA A;  4YHX A;  2EX5 A;  1LWT A;  4AAG A;  2QOJ Z; 
#chains in the Genus database with same CATH homology
 2XE0 A;  1R7M A;  1B24 A;  5AKN A;  1T9J A;  3R7P A;  3C0X A;  4UN9 A;  1N3F A;  4UT0 A;  3FD2 A;  4D6O A;  4UN7 A;  1UM2 A;  5E63 A;  1G9Z A;  5A77 A;  2AB5 A;  5E67 A;  5AK9 A;  2I3P A;  3E54 A;  4Z20 A;  2XE0 B;  5A0W A;  2VS8 A;  5E5O A;  3KO2 A;  4UN8 A;  3C0W A;  2VBJ A;  3OOL A;  1EF0 A;  4AQU A;  4YIT A;  5A78 A;  3MXB A;  3MX9 A;  3HYI A;  3MXA A;  5E5S A;  1VDE A;  5A0M A;  3QQY A;  3MIP A;  2VBJ B;  1U0C A;  4AAE A;  1U0D A;  4LQ0 A;  2VBO A;  4AAD A;  3MXB B;  2VBN A;  4D6N A;  4AQX A;  4AAF A;  1N3E A;  4UNC A;  2FLD A;  5AKF A;  4Z1Z A;  3EH8 A;  3HYJ A;  5A0M B;  4UN9 G;  1LWS A;  2DCH X;  2CW7 A;  3OOR A;  4UN7 G;  2VBO B;  2VBN B;  1AF5 A;  1JVA A;  2O7M A;  1G9Y A;  4AAB A;  1DQ3 A;  4EFJ A;  3MIS A;  2I3Q A;  2VBL A;  4UN8 G;  4UNB A;  4LOX A;  1DFA A;  1M5X A;  4YIS A;  1MOW A;  2VBL B;  3UVF A;  5A74 A;  5AKM A;  1P8K Z;  5A72 A;  2VS7 A;  1T9I A;  4Z1X A;  2CW8 A;  1BP7 A;  4UNA A;  4YHX A;  2EX5 A;  1LWT A;  4AAG A;  2QOJ Z; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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