4AAFA

Crystal structure of the mutant d75n i-crei in complex with an altered target (the four central bases, 2nn region, are composed by tgca from 5' to 3')
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
151
structure length
151
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 48
structure length 151
sequence length 151
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aafA00
3HYJA 4YISA 4UN9A 2VBJB 2VS8A 1M5XA 3UVFA 1G9YA 3HYIA 4UN7G 1B24A 4Z1XA 2XE0B 3FD2A 2CW7A 4D6NA 1N3FA 2EX5A 5AK9A 1R7MA 4LQ0A 4UNCA 1U0DA 5E5SA 1EF0A 2VBLB 3OORA 3MIPA 5A74A 5A0MB 2FLDA 2VS7A 1AF5A 2DCHX 2AB5A 1N3EA 3MXAA 4AADA 1DQ3A 1BP7A 4UN8A 4UNBA 1VDEA 4UN9G 3KO2A 2VBJA 4YITA 3MISA 4AQUA 1UM2A 2VBOB 1U0CA 3MXBB 1T9IA 2VBNB 2XE0A 5E5OA 5A78A 4Z1ZA 1T9JA 5AKMA 4UN7A 3EH8A 1G9ZA 5AKNA 2O7MA 2VBLA 5E63A 4YHXA 5A0MA 3MX9A 1LWSA 1JVAA 4Z20A 4UNAA 4AABA 3QQYA 3OOLA 4UN8G 5E67A 2I3PA 1DFAA 4AAGA 4UT0A 5AKFA 1LWTA 4AAEA 2VBOA 3E54A 3MXBA 2VBNA 5A72A 3C0XA 3C0WA 4AQXA 4AAFA 2CW8A 2QOJZ 1P8KZ 5A77A 2I3QA 1MOWA 4LOXA 3R7PA 5A0WA 4D6OA 4EFJA
chains in the Genus database with same CATH superfamily
3HYJA 4YISA 4UN9A 2VBJB 2VS8A 1M5XA 3UVFA 1G9YA 3HYIA 4UN7G 1B24A 4Z1XA 2XE0B 3FD2A 2CW7A 4D6NA 1N3FA 2EX5A 5AK9A 1R7MA 4LQ0A 4UNCA 1U0DA 5E5SA 1EF0A 2VBLB 3OORA 3MIPA 5A74A 5A0MB 2FLDA 2VS7A 1AF5A 2DCHX 2AB5A 1N3EA 3MXAA 4AADA 1DQ3A 1BP7A 4UN8A 4UNBA 1VDEA 4UN9G 3KO2A 2VBJA 4YITA 3MISA 4AQUA 1UM2A 2VBOB 1U0CA 3MXBB 1T9IA 2VBNB 2XE0A 5E5OA 5A78A 4Z1ZA 1T9JA 5AKMA 4UN7A 3EH8A 1G9ZA 5AKNA 2O7MA 2VBLA 5E63A 4YHXA 5A0MA 3MX9A 1LWSA 1JVAA 4Z20A 2F4LA 4UNAA 4AABA 3QQYA 3OOLA 4UN8G 5E67A 2I3PA 1DFAA 4AAGA 4UT0A 5AKFA 4KZSA 1LWTA 4AAEA 2VBOA 3E54A 3MXBA 2VBNA 5A72A 3C0XA 3C0WA 4AQXA 4AAFA 2CW8A 2QOJZ 1P8KZ 5A77A 2I3QA 1MOWA 4LOXA 3R7PA 5A0WA 4D6OA 4EFJA
chains in the Genus database with same CATH topology
3HYJA 4YISA 4UN9A 2VBJB 2VS8A 1M5XA 3UVFA 1G9YA 3HYIA 4UN7G 1B24A 4Z1XA 2XE0B 3FD2A 2CW7A 4D6NA 1N3FA 2EX5A 5AK9A 1R7MA 4LQ0A 4UNCA 1U0DA 5E5SA 1EF0A 2VBLB 3OORA 3MIPA 5A74A 5A0MB 2FLDA 2VS7A 1AF5A 2DCHX 2AB5A 1N3EA 3MXAA 4AADA 1DQ3A 1BP7A 4UN8A 4UNBA 1VDEA 4UN9G 3KO2A 2VBJA 4YITA 3MISA 4AQUA 1UM2A 2VBOB 1U0CA 3MXBB 1T9IA 2VBNB 2XE0A 5E5OA 5A78A 4Z1ZA 1T9JA 5AKMA 4UN7A 3EH8A 1G9ZA 5AKNA 2O7MA 2VBLA 5E63A 4YHXA 5A0MA 3MX9A 1LWSA 1JVAA 4Z20A 4UNAA 4AABA 3QQYA 3OOLA 4UN8G 5E67A 2I3PA 1DFAA 4AAGA 4UT0A 5AKFA 1LWTA 4AAEA 2VBOA 3E54A 3MXBA 2VBNA 5A72A 3C0XA 3C0WA 4AQXA 4AAFA 2CW8A 2QOJZ 1P8KZ 5A77A 2I3QA 1MOWA 4LOXA 3R7PA 5A0WA 4D6OA 4EFJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HYJ A;  4YIS A;  4UN9 A;  2VBJ B;  2VS8 A;  1M5X A;  3UVF A;  1G9Y A;  3HYI A;  4UN7 G;  1B24 A;  4Z1X A;  2XE0 B;  3FD2 A;  2CW7 A;  4D6N A;  1N3F A;  2EX5 A;  5AK9 A;  1R7M A;  4LQ0 A;  4UNC A;  1U0D A;  5E5S A;  1EF0 A;  2VBL B;  3OOR A;  3MIP A;  5A74 A;  5A0M B;  2FLD A;  2VS7 A;  1AF5 A;  2DCH X;  2AB5 A;  1N3E A;  3MXA A;  4AAD A;  1DQ3 A;  1BP7 A;  4UN8 A;  4UNB A;  1VDE A;  4UN9 G;  3KO2 A;  2VBJ A;  4YIT A;  3MIS A;  4AQU A;  1UM2 A;  2VBO B;  1U0C A;  3MXB B;  1T9I A;  2VBN B;  2XE0 A;  5E5O A;  5A78 A;  4Z1Z A;  1T9J A;  5AKM A;  4UN7 A;  3EH8 A;  1G9Z A;  5AKN A;  2O7M A;  2VBL A;  5E63 A;  4YHX A;  5A0M A;  3MX9 A;  1LWS A;  1JVA A;  4Z20 A;  4UNA A;  4AAB A;  3QQY A;  3OOL A;  4UN8 G;  5E67 A;  2I3P A;  1DFA A;  4AAG A;  4UT0 A;  5AKF A;  1LWT A;  4AAE A;  2VBO A;  3E54 A;  3MXB A;  2VBN A;  5A72 A;  3C0X A;  3C0W A;  4AQX A;  4AAF A;  2CW8 A;  2QOJ Z;  1P8K Z;  5A77 A;  2I3Q A;  1MOW A;  4LOX A;  3R7P A;  5A0W A;  4D6O A;  4EFJ A; 
#chains in the Genus database with same CATH topology
 3HYJ A;  4YIS A;  4UN9 A;  2VBJ B;  2VS8 A;  1M5X A;  3UVF A;  1G9Y A;  3HYI A;  4UN7 G;  1B24 A;  4Z1X A;  2XE0 B;  3FD2 A;  2CW7 A;  4D6N A;  1N3F A;  2EX5 A;  5AK9 A;  1R7M A;  4LQ0 A;  4UNC A;  1U0D A;  5E5S A;  1EF0 A;  2VBL B;  3OOR A;  3MIP A;  5A74 A;  5A0M B;  2FLD A;  2VS7 A;  1AF5 A;  2DCH X;  2AB5 A;  1N3E A;  3MXA A;  4AAD A;  1DQ3 A;  1BP7 A;  4UN8 A;  4UNB A;  1VDE A;  4UN9 G;  3KO2 A;  2VBJ A;  4YIT A;  3MIS A;  4AQU A;  1UM2 A;  2VBO B;  1U0C A;  3MXB B;  1T9I A;  2VBN B;  2XE0 A;  5E5O A;  5A78 A;  4Z1Z A;  1T9J A;  5AKM A;  4UN7 A;  3EH8 A;  1G9Z A;  5AKN A;  2O7M A;  2VBL A;  5E63 A;  4YHX A;  5A0M A;  3MX9 A;  1LWS A;  1JVA A;  4Z20 A;  2F4L A;  4UNA A;  4AAB A;  3QQY A;  3OOL A;  4UN8 G;  5E67 A;  2I3P A;  1DFA A;  4AAG A;  4UT0 A;  5AKF A;  4KZS A;  1LWT A;  4AAE A;  2VBO A;  3E54 A;  3MXB A;  2VBN A;  5A72 A;  3C0X A;  3C0W A;  4AQX A;  4AAF A;  2CW8 A;  2QOJ Z;  1P8K Z;  5A77 A;  2I3Q A;  1MOW A;  4LOX A;  3R7P A;  5A0W A;  4D6O A;  4EFJ A; 
#chains in the Genus database with same CATH homology
 3HYJ A;  4YIS A;  4UN9 A;  2VBJ B;  2VS8 A;  1M5X A;  3UVF A;  1G9Y A;  3HYI A;  4UN7 G;  1B24 A;  4Z1X A;  2XE0 B;  3FD2 A;  2CW7 A;  4D6N A;  1N3F A;  2EX5 A;  5AK9 A;  1R7M A;  4LQ0 A;  4UNC A;  1U0D A;  5E5S A;  1EF0 A;  2VBL B;  3OOR A;  3MIP A;  5A74 A;  5A0M B;  2FLD A;  2VS7 A;  1AF5 A;  2DCH X;  2AB5 A;  1N3E A;  3MXA A;  4AAD A;  1DQ3 A;  1BP7 A;  4UN8 A;  4UNB A;  1VDE A;  4UN9 G;  3KO2 A;  2VBJ A;  4YIT A;  3MIS A;  4AQU A;  1UM2 A;  2VBO B;  1U0C A;  3MXB B;  1T9I A;  2VBN B;  2XE0 A;  5E5O A;  5A78 A;  4Z1Z A;  1T9J A;  5AKM A;  4UN7 A;  3EH8 A;  1G9Z A;  5AKN A;  2O7M A;  2VBL A;  5E63 A;  4YHX A;  5A0M A;  3MX9 A;  1LWS A;  1JVA A;  4Z20 A;  4UNA A;  4AAB A;  3QQY A;  3OOL A;  4UN8 G;  5E67 A;  2I3P A;  1DFA A;  4AAG A;  4UT0 A;  5AKF A;  1LWT A;  4AAE A;  2VBO A;  3E54 A;  3MXB A;  2VBN A;  5A72 A;  3C0X A;  3C0W A;  4AQX A;  4AAF A;  2CW8 A;  2QOJ Z;  1P8K Z;  5A77 A;  2I3Q A;  1MOW A;  4LOX A;  3R7P A;  5A0W A;  4D6O A;  4EFJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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