4AAGA

Crystal structure of the mutant d75n i-crei in complex with its wild- type target in presence of ca at the active site (the four central bases, 2nn region, are composed by gtac from 5' to 3')
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 49
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aagA00
1EF0A 1G9ZA 2FLDA 2CW8A 2XE0B 3E54A 4LOXA 3C0WA 5A78A 5A72A 1P8KZ 4UT0A 1M5XA 1AF5A 4YISA 2DCHX 1JVAA 1LWSA 4UN9G 1VDEA 3HYJA 3MXBB 4AAGA 2VBOA 1N3FA 2I3PA 5AKNA 2VBNA 1BP7A 3R7PA 5AKFA 4AAFA 1T9JA 2VBJA 1G9YA 2VBLA 4UN8G 4UN7G 3QQYA 4YHXA 3UVFA 2VBOB 2VBNB 3MX9A 1T9IA 4AQUA 1DQ3A 3FD2A 4Z20A 5A0WA 1UM2A 4UNAA 3EH8A 5A0MA 2VS7A 4AAEA 4LQ0A 5E5SA 2VBJB 2QOJZ 2VBLB 1R7MA 1LWTA 5E63A 4AADA 4AABA 5A74A 1MOWA 3OOLA 3MISA 5AK9A 2VS8A 4UNBA 4Z1XA 4D6OA 1U0DA 4UN9A 4Z1ZA 4AQXA 4YITA 2O7MA 1N3EA 1U0CA 5E5OA 4D6NA 1DFAA 4UNCA 5A77A 2XE0A 5AKMA 3KO2A 1B24A 3MXBA 3OORA 2AB5A 2CW7A 4UN8A 5E67A 4UN7A 3C0XA 3MIPA 3HYIA 2EX5A 4EFJA 5A0MB 2I3QA 3MXAA
chains in the Genus database with same CATH superfamily
1EF0A 1G9ZA 2FLDA 2CW8A 2XE0B 3E54A 4LOXA 3C0WA 5A78A 5A72A 1P8KZ 4UT0A 1M5XA 1AF5A 4YISA 2DCHX 1JVAA 1LWSA 4UN9G 1VDEA 3HYJA 3MXBB 4AAGA 2VBOA 1N3FA 2I3PA 5AKNA 2VBNA 1BP7A 3R7PA 5AKFA 4AAFA 1T9JA 2VBJA 1G9YA 2VBLA 4UN8G 4UN7G 3QQYA 2F4LA 4YHXA 3UVFA 2VBOB 2VBNB 3MX9A 1T9IA 4AQUA 1DQ3A 3FD2A 4Z20A 4KZSA 5A0WA 1UM2A 4UNAA 3EH8A 5A0MA 2VS7A 4AAEA 4LQ0A 5E5SA 2VBJB 2QOJZ 2VBLB 1R7MA 1LWTA 5E63A 4AADA 4AABA 5A74A 1MOWA 3OOLA 3MISA 5AK9A 2VS8A 4UNBA 4Z1XA 4D6OA 1U0DA 4UN9A 4Z1ZA 4AQXA 4YITA 2O7MA 1N3EA 1U0CA 5E5OA 4D6NA 1DFAA 4UNCA 5A77A 2XE0A 5AKMA 3KO2A 1B24A 3MXBA 3OORA 2AB5A 2CW7A 4UN8A 5E67A 4UN7A 3C0XA 3MIPA 3HYIA 2EX5A 4EFJA 5A0MB 2I3QA 3MXAA
chains in the Genus database with same CATH topology
1EF0A 1G9ZA 2FLDA 2CW8A 2XE0B 3E54A 4LOXA 3C0WA 5A78A 5A72A 1P8KZ 4UT0A 1M5XA 1AF5A 4YISA 2DCHX 1JVAA 1LWSA 4UN9G 1VDEA 3HYJA 3MXBB 4AAGA 2VBOA 1N3FA 2I3PA 5AKNA 2VBNA 1BP7A 3R7PA 5AKFA 4AAFA 1T9JA 2VBJA 1G9YA 2VBLA 4UN8G 4UN7G 3QQYA 4YHXA 3UVFA 2VBOB 2VBNB 3MX9A 1T9IA 4AQUA 1DQ3A 3FD2A 4Z20A 5A0WA 1UM2A 4UNAA 3EH8A 5A0MA 2VS7A 4AAEA 4LQ0A 5E5SA 2VBJB 2QOJZ 2VBLB 1R7MA 1LWTA 5E63A 4AADA 4AABA 5A74A 1MOWA 3OOLA 3MISA 5AK9A 2VS8A 4UNBA 4Z1XA 4D6OA 1U0DA 4UN9A 4Z1ZA 4AQXA 4YITA 2O7MA 1N3EA 1U0CA 5E5OA 4D6NA 1DFAA 4UNCA 5A77A 2XE0A 5AKMA 3KO2A 1B24A 3MXBA 3OORA 2AB5A 2CW7A 4UN8A 5E67A 4UN7A 3C0XA 3MIPA 3HYIA 2EX5A 4EFJA 5A0MB 2I3QA 3MXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EF0 A;  1G9Z A;  2FLD A;  2CW8 A;  2XE0 B;  3E54 A;  4LOX A;  3C0W A;  5A78 A;  5A72 A;  1P8K Z;  4UT0 A;  1M5X A;  1AF5 A;  4YIS A;  2DCH X;  1JVA A;  1LWS A;  4UN9 G;  1VDE A;  3HYJ A;  3MXB B;  4AAG A;  2VBO A;  1N3F A;  2I3P A;  5AKN A;  2VBN A;  1BP7 A;  3R7P A;  5AKF A;  4AAF A;  1T9J A;  2VBJ A;  1G9Y A;  2VBL A;  4UN8 G;  4UN7 G;  3QQY A;  4YHX A;  3UVF A;  2VBO B;  2VBN B;  3MX9 A;  1T9I A;  4AQU A;  1DQ3 A;  3FD2 A;  4Z20 A;  5A0W A;  1UM2 A;  4UNA A;  3EH8 A;  5A0M A;  2VS7 A;  4AAE A;  4LQ0 A;  5E5S A;  2VBJ B;  2QOJ Z;  2VBL B;  1R7M A;  1LWT A;  5E63 A;  4AAD A;  4AAB A;  5A74 A;  1MOW A;  3OOL A;  3MIS A;  5AK9 A;  2VS8 A;  4UNB A;  4Z1X A;  4D6O A;  1U0D A;  4UN9 A;  4Z1Z A;  4AQX A;  4YIT A;  2O7M A;  1N3E A;  1U0C A;  5E5O A;  4D6N A;  1DFA A;  4UNC A;  5A77 A;  2XE0 A;  5AKM A;  3KO2 A;  1B24 A;  3MXB A;  3OOR A;  2AB5 A;  2CW7 A;  4UN8 A;  5E67 A;  4UN7 A;  3C0X A;  3MIP A;  3HYI A;  2EX5 A;  4EFJ A;  5A0M B;  2I3Q A;  3MXA A; 
#chains in the Genus database with same CATH topology
 1EF0 A;  1G9Z A;  2FLD A;  2CW8 A;  2XE0 B;  3E54 A;  4LOX A;  3C0W A;  5A78 A;  5A72 A;  1P8K Z;  4UT0 A;  1M5X A;  1AF5 A;  4YIS A;  2DCH X;  1JVA A;  1LWS A;  4UN9 G;  1VDE A;  3HYJ A;  3MXB B;  4AAG A;  2VBO A;  1N3F A;  2I3P A;  5AKN A;  2VBN A;  1BP7 A;  3R7P A;  5AKF A;  4AAF A;  1T9J A;  2VBJ A;  1G9Y A;  2VBL A;  4UN8 G;  4UN7 G;  3QQY A;  2F4L A;  4YHX A;  3UVF A;  2VBO B;  2VBN B;  3MX9 A;  1T9I A;  4AQU A;  1DQ3 A;  3FD2 A;  4Z20 A;  4KZS A;  5A0W A;  1UM2 A;  4UNA A;  3EH8 A;  5A0M A;  2VS7 A;  4AAE A;  4LQ0 A;  5E5S A;  2VBJ B;  2QOJ Z;  2VBL B;  1R7M A;  1LWT A;  5E63 A;  4AAD A;  4AAB A;  5A74 A;  1MOW A;  3OOL A;  3MIS A;  5AK9 A;  2VS8 A;  4UNB A;  4Z1X A;  4D6O A;  1U0D A;  4UN9 A;  4Z1Z A;  4AQX A;  4YIT A;  2O7M A;  1N3E A;  1U0C A;  5E5O A;  4D6N A;  1DFA A;  4UNC A;  5A77 A;  2XE0 A;  5AKM A;  3KO2 A;  1B24 A;  3MXB A;  3OOR A;  2AB5 A;  2CW7 A;  4UN8 A;  5E67 A;  4UN7 A;  3C0X A;  3MIP A;  3HYI A;  2EX5 A;  4EFJ A;  5A0M B;  2I3Q A;  3MXA A; 
#chains in the Genus database with same CATH homology
 1EF0 A;  1G9Z A;  2FLD A;  2CW8 A;  2XE0 B;  3E54 A;  4LOX A;  3C0W A;  5A78 A;  5A72 A;  1P8K Z;  4UT0 A;  1M5X A;  1AF5 A;  4YIS A;  2DCH X;  1JVA A;  1LWS A;  4UN9 G;  1VDE A;  3HYJ A;  3MXB B;  4AAG A;  2VBO A;  1N3F A;  2I3P A;  5AKN A;  2VBN A;  1BP7 A;  3R7P A;  5AKF A;  4AAF A;  1T9J A;  2VBJ A;  1G9Y A;  2VBL A;  4UN8 G;  4UN7 G;  3QQY A;  4YHX A;  3UVF A;  2VBO B;  2VBN B;  3MX9 A;  1T9I A;  4AQU A;  1DQ3 A;  3FD2 A;  4Z20 A;  5A0W A;  1UM2 A;  4UNA A;  3EH8 A;  5A0M A;  2VS7 A;  4AAE A;  4LQ0 A;  5E5S A;  2VBJ B;  2QOJ Z;  2VBL B;  1R7M A;  1LWT A;  5E63 A;  4AAD A;  4AAB A;  5A74 A;  1MOW A;  3OOL A;  3MIS A;  5AK9 A;  2VS8 A;  4UNB A;  4Z1X A;  4D6O A;  1U0D A;  4UN9 A;  4Z1Z A;  4AQX A;  4YIT A;  2O7M A;  1N3E A;  1U0C A;  5E5O A;  4D6N A;  1DFA A;  4UNC A;  5A77 A;  2XE0 A;  5AKM A;  3KO2 A;  1B24 A;  3MXB A;  3OOR A;  2AB5 A;  2CW7 A;  4UN8 A;  5E67 A;  4UN7 A;  3C0X A;  3MIP A;  3HYI A;  2EX5 A;  4EFJ A;  5A0M B;  2I3Q A;  3MXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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