4AAGA

Crystal structure of the mutant d75n i-crei in complex with its wild- type target in presence of ca at the active site (the four central bases, 2nn region, are composed by gtac from 5' to 3')
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 49
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aagA00
3FD2A 1N3EA 4UN7G 1MOWA 1U0CA 4UNCA 1R7MA 5A74A 2VBOB 5AKMA 4YITA 1AF5A 2VBNA 3QQYA 2VBJA 3OOLA 2VBLA 3E54A 5E63A 4UNBA 2XE0A 4UNAA 2VS8A 4EFJA 4Z1XA 2CW8A 5AKFA 4YHXA 3MXBB 1G9YA 4UN8A 4AADA 3C0WA 5A0WA 1DQ3A 5AK9A 4AQUA 4AAEA 3KO2A 1UM2A 2VBOA 1JVAA 5E5SA 4AAFA 5E67A 4UN9A 4Z20A 5A72A 3MX9A 2I3QA 4LOXA 1LWSA 3OORA 4UN7A 1N3FA 2QOJZ 1B24A 1VDEA 1T9IA 4D6OA 1LWTA 4LQ0A 5A0MB 5A77A 1T9JA 5A78A 3R7PA 3HYIA 3MXBA 4AABA 1BP7A 4AAGA 2CW7A 3MXAA 4AQXA 5E5OA 1EF0A 1G9ZA 2O7MA 3MIPA 4UT0A 4UN8G 4YISA 3HYJA 3MISA 1U0DA 2FLDA 2VBNB 4D6NA 2VBJB 1DFAA 5AKNA 2VBLB 1M5XA 2AB5A 2DCHX 2XE0B 3EH8A 2I3PA 2EX5A 4UN9G 1P8KZ 3C0XA 2VS7A 5A0MA 3UVFA 4Z1ZA
chains in the Genus database with same CATH superfamily
3FD2A 1N3EA 4UN7G 1MOWA 1U0CA 4UNCA 1R7MA 5A74A 2VBOB 5AKMA 4YITA 1AF5A 2VBNA 3QQYA 2VBJA 3OOLA 2VBLA 3E54A 5E63A 4UNBA 2XE0A 4UNAA 2VS8A 4EFJA 4Z1XA 2CW8A 5AKFA 4YHXA 3MXBB 1G9YA 4UN8A 4AADA 3C0WA 5A0WA 1DQ3A 5AK9A 4AQUA 4AAEA 3KO2A 1UM2A 2VBOA 1JVAA 5E5SA 4AAFA 5E67A 4UN9A 4Z20A 5A72A 3MX9A 2I3QA 4LOXA 1LWSA 3OORA 4UN7A 1N3FA 2QOJZ 1B24A 1VDEA 1T9IA 4D6OA 1LWTA 4LQ0A 5A0MB 5A77A 1T9JA 5A78A 3R7PA 3HYIA 3MXBA 4AABA 1BP7A 4AAGA 2CW7A 3MXAA 4KZSA 4AQXA 2F4LA 5E5OA 1EF0A 1G9ZA 2O7MA 3MIPA 4UT0A 4UN8G 4YISA 3HYJA 3MISA 1U0DA 2FLDA 2VBNB 4D6NA 2VBJB 1DFAA 5AKNA 2VBLB 1M5XA 2AB5A 2DCHX 2XE0B 3EH8A 2I3PA 2EX5A 4UN9G 1P8KZ 3C0XA 2VS7A 5A0MA 3UVFA 4Z1ZA
chains in the Genus database with same CATH topology
3FD2A 1N3EA 4UN7G 1MOWA 1U0CA 4UNCA 1R7MA 5A74A 2VBOB 5AKMA 4YITA 1AF5A 2VBNA 3QQYA 2VBJA 3OOLA 2VBLA 3E54A 5E63A 4UNBA 2XE0A 4UNAA 2VS8A 4EFJA 4Z1XA 2CW8A 5AKFA 4YHXA 3MXBB 1G9YA 4UN8A 4AADA 3C0WA 5A0WA 1DQ3A 5AK9A 4AQUA 4AAEA 3KO2A 1UM2A 2VBOA 1JVAA 5E5SA 4AAFA 5E67A 4UN9A 4Z20A 5A72A 3MX9A 2I3QA 4LOXA 1LWSA 3OORA 4UN7A 1N3FA 2QOJZ 1B24A 1VDEA 1T9IA 4D6OA 1LWTA 4LQ0A 5A0MB 5A77A 1T9JA 5A78A 3R7PA 3HYIA 3MXBA 4AABA 1BP7A 4AAGA 2CW7A 3MXAA 4AQXA 5E5OA 1EF0A 1G9ZA 2O7MA 3MIPA 4UT0A 4UN8G 4YISA 3HYJA 3MISA 1U0DA 2FLDA 2VBNB 4D6NA 2VBJB 1DFAA 5AKNA 2VBLB 1M5XA 2AB5A 2DCHX 2XE0B 3EH8A 2I3PA 2EX5A 4UN9G 1P8KZ 3C0XA 2VS7A 5A0MA 3UVFA 4Z1ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FD2 A;  1N3E A;  4UN7 G;  1MOW A;  1U0C A;  4UNC A;  1R7M A;  5A74 A;  2VBO B;  5AKM A;  4YIT A;  1AF5 A;  2VBN A;  3QQY A;  2VBJ A;  3OOL A;  2VBL A;  3E54 A;  5E63 A;  4UNB A;  2XE0 A;  4UNA A;  2VS8 A;  4EFJ A;  4Z1X A;  2CW8 A;  5AKF A;  4YHX A;  3MXB B;  1G9Y A;  4UN8 A;  4AAD A;  3C0W A;  5A0W A;  1DQ3 A;  5AK9 A;  4AQU A;  4AAE A;  3KO2 A;  1UM2 A;  2VBO A;  1JVA A;  5E5S A;  4AAF A;  5E67 A;  4UN9 A;  4Z20 A;  5A72 A;  3MX9 A;  2I3Q A;  4LOX A;  1LWS A;  3OOR A;  4UN7 A;  1N3F A;  2QOJ Z;  1B24 A;  1VDE A;  1T9I A;  4D6O A;  1LWT A;  4LQ0 A;  5A0M B;  5A77 A;  1T9J A;  5A78 A;  3R7P A;  3HYI A;  3MXB A;  4AAB A;  1BP7 A;  4AAG A;  2CW7 A;  3MXA A;  4AQX A;  5E5O A;  1EF0 A;  1G9Z A;  2O7M A;  3MIP A;  4UT0 A;  4UN8 G;  4YIS A;  3HYJ A;  3MIS A;  1U0D A;  2FLD A;  2VBN B;  4D6N A;  2VBJ B;  1DFA A;  5AKN A;  2VBL B;  1M5X A;  2AB5 A;  2DCH X;  2XE0 B;  3EH8 A;  2I3P A;  2EX5 A;  4UN9 G;  1P8K Z;  3C0X A;  2VS7 A;  5A0M A;  3UVF A;  4Z1Z A; 
#chains in the Genus database with same CATH topology
 3FD2 A;  1N3E A;  4UN7 G;  1MOW A;  1U0C A;  4UNC A;  1R7M A;  5A74 A;  2VBO B;  5AKM A;  4YIT A;  1AF5 A;  2VBN A;  3QQY A;  2VBJ A;  3OOL A;  2VBL A;  3E54 A;  5E63 A;  4UNB A;  2XE0 A;  4UNA A;  2VS8 A;  4EFJ A;  4Z1X A;  2CW8 A;  5AKF A;  4YHX A;  3MXB B;  1G9Y A;  4UN8 A;  4AAD A;  3C0W A;  5A0W A;  1DQ3 A;  5AK9 A;  4AQU A;  4AAE A;  3KO2 A;  1UM2 A;  2VBO A;  1JVA A;  5E5S A;  4AAF A;  5E67 A;  4UN9 A;  4Z20 A;  5A72 A;  3MX9 A;  2I3Q A;  4LOX A;  1LWS A;  3OOR A;  4UN7 A;  1N3F A;  2QOJ Z;  1B24 A;  1VDE A;  1T9I A;  4D6O A;  1LWT A;  4LQ0 A;  5A0M B;  5A77 A;  1T9J A;  5A78 A;  3R7P A;  3HYI A;  3MXB A;  4AAB A;  1BP7 A;  4AAG A;  2CW7 A;  3MXA A;  4KZS A;  4AQX A;  2F4L A;  5E5O A;  1EF0 A;  1G9Z A;  2O7M A;  3MIP A;  4UT0 A;  4UN8 G;  4YIS A;  3HYJ A;  3MIS A;  1U0D A;  2FLD A;  2VBN B;  4D6N A;  2VBJ B;  1DFA A;  5AKN A;  2VBL B;  1M5X A;  2AB5 A;  2DCH X;  2XE0 B;  3EH8 A;  2I3P A;  2EX5 A;  4UN9 G;  1P8K Z;  3C0X A;  2VS7 A;  5A0M A;  3UVF A;  4Z1Z A; 
#chains in the Genus database with same CATH homology
 3FD2 A;  1N3E A;  4UN7 G;  1MOW A;  1U0C A;  4UNC A;  1R7M A;  5A74 A;  2VBO B;  5AKM A;  4YIT A;  1AF5 A;  2VBN A;  3QQY A;  2VBJ A;  3OOL A;  2VBL A;  3E54 A;  5E63 A;  4UNB A;  2XE0 A;  4UNA A;  2VS8 A;  4EFJ A;  4Z1X A;  2CW8 A;  5AKF A;  4YHX A;  3MXB B;  1G9Y A;  4UN8 A;  4AAD A;  3C0W A;  5A0W A;  1DQ3 A;  5AK9 A;  4AQU A;  4AAE A;  3KO2 A;  1UM2 A;  2VBO A;  1JVA A;  5E5S A;  4AAF A;  5E67 A;  4UN9 A;  4Z20 A;  5A72 A;  3MX9 A;  2I3Q A;  4LOX A;  1LWS A;  3OOR A;  4UN7 A;  1N3F A;  2QOJ Z;  1B24 A;  1VDE A;  1T9I A;  4D6O A;  1LWT A;  4LQ0 A;  5A0M B;  5A77 A;  1T9J A;  5A78 A;  3R7P A;  3HYI A;  3MXB A;  4AAB A;  1BP7 A;  4AAG A;  2CW7 A;  3MXA A;  4AQX A;  5E5O A;  1EF0 A;  1G9Z A;  2O7M A;  3MIP A;  4UT0 A;  4UN8 G;  4YIS A;  3HYJ A;  3MIS A;  1U0D A;  2FLD A;  2VBN B;  4D6N A;  2VBJ B;  1DFA A;  5AKN A;  2VBL B;  1M5X A;  2AB5 A;  2DCH X;  2XE0 B;  3EH8 A;  2I3P A;  2EX5 A;  4UN9 G;  1P8K Z;  3C0X A;  2VS7 A;  5A0M A;  3UVF A;  4Z1Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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