4AAGA

Crystal structure of the mutant d75n i-crei in complex with its wild- type target in presence of ca at the active site (the four central bases, 2nn region, are composed by gtac from 5' to 3')
Total Genus 49
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSNYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Non-Specific Protein-DNA Interactions Control I-Crei Target Binding and Cleavage.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 49
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2011-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aagA00
1DQ3A 2VBJA 5AKNA 2CW7A 4Z20A 1M5XA 3HYIA 5AKFA 4UN9A 4AQXA 3MX9A 1EF0A 2I3PA 2VBNA 2VS8A 4AQUA 5A0MB 1U0CA 4AAGA 2O7MA 4D6OA 2FLDA 2XE0B 4LQ0A 2VBLA 5AK9A 4YHXA 1DFAA 3E54A 1LWSA 2VBOB 3QQYA 4LOXA 5A74A 2AB5A 4UNCA 3MIPA 5A77A 1B24A 4Z1ZA 3MXBB 2EX5A 4UNAA 5A0MA 3OOLA 3R7PA 3EH8A 3OORA 4EFJA 1T9JA 4YITA 5AKMA 3MXAA 3FD2A 4AAEA 2DCHX 4UN7G 4UNBA 4UN8G 2CW8A 5A78A 4AAFA 1LWTA 1AF5A 2VBOA 3KO2A 1UM2A 4D6NA 5A0WA 1JVAA 4UN8A 3UVFA 5E5OA 2VBJB 1R7MA 5A72A 1N3FA 4UT0A 4UN9G 4AABA 2XE0A 3C0XA 2VBNB 1VDEA 2QOJZ 3MISA 3HYJA 5E63A 1G9ZA 2VS7A 4AADA 4Z1XA 3C0WA 4UN7A 1MOWA 2I3QA 2VBLB 1N3EA 1BP7A 1G9YA 5E5SA 3MXBA 1P8KZ 4YISA 1T9IA 5E67A 1U0DA
chains in the Genus database with same CATH superfamily
1DQ3A 2VBJA 5AKNA 2CW7A 4Z20A 1M5XA 3HYIA 2F4LA 5AKFA 4UN9A 4AQXA 3MX9A 1EF0A 2I3PA 2VBNA 2VS8A 4AQUA 5A0MB 1U0CA 4AAGA 2O7MA 4D6OA 2FLDA 2XE0B 4LQ0A 2VBLA 5AK9A 4YHXA 1DFAA 3E54A 1LWSA 2VBOB 3QQYA 4LOXA 5A74A 2AB5A 4UNCA 3MIPA 5A77A 1B24A 4Z1ZA 3MXBB 2EX5A 4UNAA 5A0MA 3OOLA 3R7PA 3EH8A 3OORA 4EFJA 1T9JA 4YITA 5AKMA 3MXAA 3FD2A 4AAEA 2DCHX 4UN7G 4UNBA 4UN8G 2CW8A 5A78A 4AAFA 1LWTA 1AF5A 2VBOA 3KO2A 1UM2A 4D6NA 5A0WA 1JVAA 4UN8A 3UVFA 5E5OA 2VBJB 1R7MA 5A72A 1N3FA 4UT0A 4UN9G 4AABA 2XE0A 3C0XA 2VBNB 1VDEA 2QOJZ 3MISA 3HYJA 5E63A 1G9ZA 2VS7A 4KZSA 4AADA 4Z1XA 3C0WA 4UN7A 1MOWA 2I3QA 2VBLB 1N3EA 1BP7A 1G9YA 5E5SA 3MXBA 1P8KZ 4YISA 1T9IA 5E67A 1U0DA
chains in the Genus database with same CATH topology
1DQ3A 2VBJA 5AKNA 2CW7A 4Z20A 1M5XA 3HYIA 5AKFA 4UN9A 4AQXA 3MX9A 1EF0A 2I3PA 2VBNA 2VS8A 4AQUA 5A0MB 1U0CA 4AAGA 2O7MA 4D6OA 2FLDA 2XE0B 4LQ0A 2VBLA 5AK9A 4YHXA 1DFAA 3E54A 1LWSA 2VBOB 3QQYA 4LOXA 5A74A 2AB5A 4UNCA 3MIPA 5A77A 1B24A 4Z1ZA 3MXBB 2EX5A 4UNAA 5A0MA 3OOLA 3R7PA 3EH8A 3OORA 4EFJA 1T9JA 4YITA 5AKMA 3MXAA 3FD2A 4AAEA 2DCHX 4UN7G 4UNBA 4UN8G 2CW8A 5A78A 4AAFA 1LWTA 1AF5A 2VBOA 3KO2A 1UM2A 4D6NA 5A0WA 1JVAA 4UN8A 3UVFA 5E5OA 2VBJB 1R7MA 5A72A 1N3FA 4UT0A 4UN9G 4AABA 2XE0A 3C0XA 2VBNB 1VDEA 2QOJZ 3MISA 3HYJA 5E63A 1G9ZA 2VS7A 4AADA 4Z1XA 3C0WA 4UN7A 1MOWA 2I3QA 2VBLB 1N3EA 1BP7A 1G9YA 5E5SA 3MXBA 1P8KZ 4YISA 1T9IA 5E67A 1U0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DQ3 A;  2VBJ A;  5AKN A;  2CW7 A;  4Z20 A;  1M5X A;  3HYI A;  5AKF A;  4UN9 A;  4AQX A;  3MX9 A;  1EF0 A;  2I3P A;  2VBN A;  2VS8 A;  4AQU A;  5A0M B;  1U0C A;  4AAG A;  2O7M A;  4D6O A;  2FLD A;  2XE0 B;  4LQ0 A;  2VBL A;  5AK9 A;  4YHX A;  1DFA A;  3E54 A;  1LWS A;  2VBO B;  3QQY A;  4LOX A;  5A74 A;  2AB5 A;  4UNC A;  3MIP A;  5A77 A;  1B24 A;  4Z1Z A;  3MXB B;  2EX5 A;  4UNA A;  5A0M A;  3OOL A;  3R7P A;  3EH8 A;  3OOR A;  4EFJ A;  1T9J A;  4YIT A;  5AKM A;  3MXA A;  3FD2 A;  4AAE A;  2DCH X;  4UN7 G;  4UNB A;  4UN8 G;  2CW8 A;  5A78 A;  4AAF A;  1LWT A;  1AF5 A;  2VBO A;  3KO2 A;  1UM2 A;  4D6N A;  5A0W A;  1JVA A;  4UN8 A;  3UVF A;  5E5O A;  2VBJ B;  1R7M A;  5A72 A;  1N3F A;  4UT0 A;  4UN9 G;  4AAB A;  2XE0 A;  3C0X A;  2VBN B;  1VDE A;  2QOJ Z;  3MIS A;  3HYJ A;  5E63 A;  1G9Z A;  2VS7 A;  4AAD A;  4Z1X A;  3C0W A;  4UN7 A;  1MOW A;  2I3Q A;  2VBL B;  1N3E A;  1BP7 A;  1G9Y A;  5E5S A;  3MXB A;  1P8K Z;  4YIS A;  1T9I A;  5E67 A;  1U0D A; 
#chains in the Genus database with same CATH topology
 1DQ3 A;  2VBJ A;  5AKN A;  2CW7 A;  4Z20 A;  1M5X A;  3HYI A;  2F4L A;  5AKF A;  4UN9 A;  4AQX A;  3MX9 A;  1EF0 A;  2I3P A;  2VBN A;  2VS8 A;  4AQU A;  5A0M B;  1U0C A;  4AAG A;  2O7M A;  4D6O A;  2FLD A;  2XE0 B;  4LQ0 A;  2VBL A;  5AK9 A;  4YHX A;  1DFA A;  3E54 A;  1LWS A;  2VBO B;  3QQY A;  4LOX A;  5A74 A;  2AB5 A;  4UNC A;  3MIP A;  5A77 A;  1B24 A;  4Z1Z A;  3MXB B;  2EX5 A;  4UNA A;  5A0M A;  3OOL A;  3R7P A;  3EH8 A;  3OOR A;  4EFJ A;  1T9J A;  4YIT A;  5AKM A;  3MXA A;  3FD2 A;  4AAE A;  2DCH X;  4UN7 G;  4UNB A;  4UN8 G;  2CW8 A;  5A78 A;  4AAF A;  1LWT A;  1AF5 A;  2VBO A;  3KO2 A;  1UM2 A;  4D6N A;  5A0W A;  1JVA A;  4UN8 A;  3UVF A;  5E5O A;  2VBJ B;  1R7M A;  5A72 A;  1N3F A;  4UT0 A;  4UN9 G;  4AAB A;  2XE0 A;  3C0X A;  2VBN B;  1VDE A;  2QOJ Z;  3MIS A;  3HYJ A;  5E63 A;  1G9Z A;  2VS7 A;  4KZS A;  4AAD A;  4Z1X A;  3C0W A;  4UN7 A;  1MOW A;  2I3Q A;  2VBL B;  1N3E A;  1BP7 A;  1G9Y A;  5E5S A;  3MXB A;  1P8K Z;  4YIS A;  1T9I A;  5E67 A;  1U0D A; 
#chains in the Genus database with same CATH homology
 1DQ3 A;  2VBJ A;  5AKN A;  2CW7 A;  4Z20 A;  1M5X A;  3HYI A;  5AKF A;  4UN9 A;  4AQX A;  3MX9 A;  1EF0 A;  2I3P A;  2VBN A;  2VS8 A;  4AQU A;  5A0M B;  1U0C A;  4AAG A;  2O7M A;  4D6O A;  2FLD A;  2XE0 B;  4LQ0 A;  2VBL A;  5AK9 A;  4YHX A;  1DFA A;  3E54 A;  1LWS A;  2VBO B;  3QQY A;  4LOX A;  5A74 A;  2AB5 A;  4UNC A;  3MIP A;  5A77 A;  1B24 A;  4Z1Z A;  3MXB B;  2EX5 A;  4UNA A;  5A0M A;  3OOL A;  3R7P A;  3EH8 A;  3OOR A;  4EFJ A;  1T9J A;  4YIT A;  5AKM A;  3MXA A;  3FD2 A;  4AAE A;  2DCH X;  4UN7 G;  4UNB A;  4UN8 G;  2CW8 A;  5A78 A;  4AAF A;  1LWT A;  1AF5 A;  2VBO A;  3KO2 A;  1UM2 A;  4D6N A;  5A0W A;  1JVA A;  4UN8 A;  3UVF A;  5E5O A;  2VBJ B;  1R7M A;  5A72 A;  1N3F A;  4UT0 A;  4UN9 G;  4AAB A;  2XE0 A;  3C0X A;  2VBN B;  1VDE A;  2QOJ Z;  3MIS A;  3HYJ A;  5E63 A;  1G9Z A;  2VS7 A;  4AAD A;  4Z1X A;  3C0W A;  4UN7 A;  1MOW A;  2I3Q A;  2VBL B;  1N3E A;  1BP7 A;  1G9Y A;  5E5S A;  3MXB A;  1P8K Z;  4YIS A;  1T9I A;  5E67 A;  1U0D A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...