4AQXA

Crystal structure of i-crei complexed with its target methylated at position plus 2 (in the b strand) in the presence of magnesium
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 5'-Cytosine-Phosphoguanine (Cpg) Methylation Impacts the Activity of Natural and Engineered Meganucleases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 51
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aqxA00
2VS7A 4Z1XA 2VBNA 4UN8A 4EFJA 3OORA 1T9IA 2VS8A 4D6NA 1B24A 3MXBA 1G9ZA 1DFAA 4UNAA 2VBNB 3R7PA 4UN9A 4AQUA 3C0XA 1N3EA 2XE0A 2VBOA 2QOJZ 5AKMA 4LOXA 2I3QA 5AK9A 2DCHX 5E5SA 3HYJA 4UNCA 4LQ0A 2FLDA 3MXBB 4Z1ZA 3QQYA 2VBJA 4YHXA 4UN7A 2EX5A 4AADA 5E67A 4AAGA 3MIPA 2XE0B 2VBOB 4AQXA 2VBLA 3FD2A 1LWTA 4YITA 4D6OA 1UM2A 4AABA 3E54A 3MISA 1BP7A 1N3FA 1G9YA 2O7MA 4UN8G 1T9JA 4AAEA 2VBJB 3MXAA 3C0WA 1P8KZ 5E63A 5AKFA 5A72A 1U0DA 2VBLB 5A0MB 1AF5A 4YISA 1VDEA 1DQ3A 5A0WA 4UT0A 1JVAA 5A0MA 4UN9G 1EF0A 3HYIA 1MOWA 1R7MA 2CW7A 2CW8A 5E5OA 4Z20A 3UVFA 5A74A 3KO2A 4AAFA 1U0CA 3OOLA 1LWSA 1M5XA 3MX9A 5AKNA 2I3PA 4UN7G 5A78A 4UNBA 2AB5A 3EH8A 5A77A
chains in the Genus database with same CATH superfamily
4KZSA 2VS7A 4Z1XA 2VBNA 4UN8A 4EFJA 3OORA 1T9IA 2VS8A 4D6NA 1B24A 3MXBA 1G9ZA 1DFAA 4UNAA 2VBNB 3R7PA 4UN9A 4AQUA 3C0XA 1N3EA 2XE0A 2VBOA 2QOJZ 5AKMA 4LOXA 2I3QA 5AK9A 2DCHX 5E5SA 3HYJA 4UNCA 4LQ0A 2FLDA 3MXBB 4Z1ZA 3QQYA 2VBJA 4YHXA 4UN7A 2EX5A 4AADA 5E67A 4AAGA 3MIPA 2XE0B 2VBOB 4AQXA 2VBLA 3FD2A 1LWTA 4YITA 4D6OA 1UM2A 4AABA 3E54A 3MISA 1BP7A 1N3FA 1G9YA 2O7MA 4UN8G 1T9JA 4AAEA 2VBJB 3MXAA 3C0WA 1P8KZ 5E63A 5AKFA 5A72A 1U0DA 2VBLB 5A0MB 2F4LA 1AF5A 4YISA 1VDEA 1DQ3A 5A0WA 4UT0A 1JVAA 5A0MA 4UN9G 1EF0A 3HYIA 1MOWA 1R7MA 2CW7A 2CW8A 5E5OA 4Z20A 3UVFA 5A74A 3KO2A 4AAFA 1U0CA 3OOLA 1LWSA 1M5XA 3MX9A 5AKNA 2I3PA 4UN7G 5A78A 4UNBA 2AB5A 3EH8A 5A77A
chains in the Genus database with same CATH topology
2VS7A 4Z1XA 2VBNA 4UN8A 4EFJA 3OORA 1T9IA 2VS8A 4D6NA 1B24A 3MXBA 1G9ZA 1DFAA 4UNAA 2VBNB 3R7PA 4UN9A 4AQUA 3C0XA 1N3EA 2XE0A 2VBOA 2QOJZ 5AKMA 4LOXA 2I3QA 5AK9A 2DCHX 5E5SA 3HYJA 4UNCA 4LQ0A 2FLDA 3MXBB 4Z1ZA 3QQYA 2VBJA 4YHXA 4UN7A 2EX5A 4AADA 5E67A 4AAGA 3MIPA 2XE0B 2VBOB 4AQXA 2VBLA 3FD2A 1LWTA 4YITA 4D6OA 1UM2A 4AABA 3E54A 3MISA 1BP7A 1N3FA 1G9YA 2O7MA 4UN8G 1T9JA 4AAEA 2VBJB 3MXAA 3C0WA 1P8KZ 5E63A 5AKFA 5A72A 1U0DA 2VBLB 5A0MB 1AF5A 4YISA 1VDEA 1DQ3A 5A0WA 4UT0A 1JVAA 5A0MA 4UN9G 1EF0A 3HYIA 1MOWA 1R7MA 2CW7A 2CW8A 5E5OA 4Z20A 3UVFA 5A74A 3KO2A 4AAFA 1U0CA 3OOLA 1LWSA 1M5XA 3MX9A 5AKNA 2I3PA 4UN7G 5A78A 4UNBA 2AB5A 3EH8A 5A77A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VS7 A;  4Z1X A;  2VBN A;  4UN8 A;  4EFJ A;  3OOR A;  1T9I A;  2VS8 A;  4D6N A;  1B24 A;  3MXB A;  1G9Z A;  1DFA A;  4UNA A;  2VBN B;  3R7P A;  4UN9 A;  4AQU A;  3C0X A;  1N3E A;  2XE0 A;  2VBO A;  2QOJ Z;  5AKM A;  4LOX A;  2I3Q A;  5AK9 A;  2DCH X;  5E5S A;  3HYJ A;  4UNC A;  4LQ0 A;  2FLD A;  3MXB B;  4Z1Z A;  3QQY A;  2VBJ A;  4YHX A;  4UN7 A;  2EX5 A;  4AAD A;  5E67 A;  4AAG A;  3MIP A;  2XE0 B;  2VBO B;  4AQX A;  2VBL A;  3FD2 A;  1LWT A;  4YIT A;  4D6O A;  1UM2 A;  4AAB A;  3E54 A;  3MIS A;  1BP7 A;  1N3F A;  1G9Y A;  2O7M A;  4UN8 G;  1T9J A;  4AAE A;  2VBJ B;  3MXA A;  3C0W A;  1P8K Z;  5E63 A;  5AKF A;  5A72 A;  1U0D A;  2VBL B;  5A0M B;  1AF5 A;  4YIS A;  1VDE A;  1DQ3 A;  5A0W A;  4UT0 A;  1JVA A;  5A0M A;  4UN9 G;  1EF0 A;  3HYI A;  1MOW A;  1R7M A;  2CW7 A;  2CW8 A;  5E5O A;  4Z20 A;  3UVF A;  5A74 A;  3KO2 A;  4AAF A;  1U0C A;  3OOL A;  1LWS A;  1M5X A;  3MX9 A;  5AKN A;  2I3P A;  4UN7 G;  5A78 A;  4UNB A;  2AB5 A;  3EH8 A;  5A77 A; 
#chains in the Genus database with same CATH topology
 4KZS A;  2VS7 A;  4Z1X A;  2VBN A;  4UN8 A;  4EFJ A;  3OOR A;  1T9I A;  2VS8 A;  4D6N A;  1B24 A;  3MXB A;  1G9Z A;  1DFA A;  4UNA A;  2VBN B;  3R7P A;  4UN9 A;  4AQU A;  3C0X A;  1N3E A;  2XE0 A;  2VBO A;  2QOJ Z;  5AKM A;  4LOX A;  2I3Q A;  5AK9 A;  2DCH X;  5E5S A;  3HYJ A;  4UNC A;  4LQ0 A;  2FLD A;  3MXB B;  4Z1Z A;  3QQY A;  2VBJ A;  4YHX A;  4UN7 A;  2EX5 A;  4AAD A;  5E67 A;  4AAG A;  3MIP A;  2XE0 B;  2VBO B;  4AQX A;  2VBL A;  3FD2 A;  1LWT A;  4YIT A;  4D6O A;  1UM2 A;  4AAB A;  3E54 A;  3MIS A;  1BP7 A;  1N3F A;  1G9Y A;  2O7M A;  4UN8 G;  1T9J A;  4AAE A;  2VBJ B;  3MXA A;  3C0W A;  1P8K Z;  5E63 A;  5AKF A;  5A72 A;  1U0D A;  2VBL B;  5A0M B;  2F4L A;  1AF5 A;  4YIS A;  1VDE A;  1DQ3 A;  5A0W A;  4UT0 A;  1JVA A;  5A0M A;  4UN9 G;  1EF0 A;  3HYI A;  1MOW A;  1R7M A;  2CW7 A;  2CW8 A;  5E5O A;  4Z20 A;  3UVF A;  5A74 A;  3KO2 A;  4AAF A;  1U0C A;  3OOL A;  1LWS A;  1M5X A;  3MX9 A;  5AKN A;  2I3P A;  4UN7 G;  5A78 A;  4UNB A;  2AB5 A;  3EH8 A;  5A77 A; 
#chains in the Genus database with same CATH homology
 2VS7 A;  4Z1X A;  2VBN A;  4UN8 A;  4EFJ A;  3OOR A;  1T9I A;  2VS8 A;  4D6N A;  1B24 A;  3MXB A;  1G9Z A;  1DFA A;  4UNA A;  2VBN B;  3R7P A;  4UN9 A;  4AQU A;  3C0X A;  1N3E A;  2XE0 A;  2VBO A;  2QOJ Z;  5AKM A;  4LOX A;  2I3Q A;  5AK9 A;  2DCH X;  5E5S A;  3HYJ A;  4UNC A;  4LQ0 A;  2FLD A;  3MXB B;  4Z1Z A;  3QQY A;  2VBJ A;  4YHX A;  4UN7 A;  2EX5 A;  4AAD A;  5E67 A;  4AAG A;  3MIP A;  2XE0 B;  2VBO B;  4AQX A;  2VBL A;  3FD2 A;  1LWT A;  4YIT A;  4D6O A;  1UM2 A;  4AAB A;  3E54 A;  3MIS A;  1BP7 A;  1N3F A;  1G9Y A;  2O7M A;  4UN8 G;  1T9J A;  4AAE A;  2VBJ B;  3MXA A;  3C0W A;  1P8K Z;  5E63 A;  5AKF A;  5A72 A;  1U0D A;  2VBL B;  5A0M B;  1AF5 A;  4YIS A;  1VDE A;  1DQ3 A;  5A0W A;  4UT0 A;  1JVA A;  5A0M A;  4UN9 G;  1EF0 A;  3HYI A;  1MOW A;  1R7M A;  2CW7 A;  2CW8 A;  5E5O A;  4Z20 A;  3UVF A;  5A74 A;  3KO2 A;  4AAF A;  1U0C A;  3OOL A;  1LWS A;  1M5X A;  3MX9 A;  5AKN A;  2I3P A;  4UN7 G;  5A78 A;  4UNB A;  2AB5 A;  3EH8 A;  5A77 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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