4AQXA

Crystal structure of i-crei complexed with its target methylated at position plus 2 (in the b strand) in the presence of magnesium
Total Genus 51
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
51
sequence length
152
structure length
152
Chain Sequence
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQRRWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAVLD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title 5'-Cytosine-Phosphoguanine (Cpg) Methylation Impacts the Activity of Natural and Engineered Meganucleases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Chlamydomonas reinhardtii
molecule keywords DNA ENDONUCLEASE I-CREI
total genus 51
structure length 152
sequence length 152
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2012-04-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4aqxA00
5A74A 1EF0A 2VBJB 3OORA 4Z20A 4UN9G 2VBLB 3MX9A 1U0DA 3FD2A 4UN9A 5AKNA 3MXAA 1BP7A 1G9ZA 4YITA 5A0MA 1DFAA 3E54A 4UNBA 2VS7A 3HYIA 1M5XA 3C0XA 3KO2A 2DCHX 4YHXA 5AKFA 2CW8A 2I3QA 1VDEA 2VBOB 5E5OA 2XE0B 3C0WA 4AAEA 4AAGA 2VBJA 2VBLA 1DQ3A 1G9YA 2EX5A 2VS8A 2CW7A 4UN8G 2I3PA 3UVFA 4UN8A 2VBNB 1AF5A 4UNAA 3OOLA 4UNCA 4Z1XA 3MXBB 4D6OA 3QQYA 5A72A 1T9IA 1UM2A 1R7MA 1B24A 3R7PA 4AABA 1T9JA 4AQXA 2FLDA 2VBOA 2QOJZ 3MISA 4UT0A 1LWSA 4AAFA 4D6NA 5AKMA 2XE0A 4LOXA 5A77A 4EFJA 4UN7G 3HYJA 1JVAA 4UN7A 4YISA 1MOWA 4LQ0A 3EH8A 5E63A 5AK9A 5A0MB 4AADA 3MIPA 1N3EA 1P8KZ 2VBNA 4AQUA 5E5SA 1U0CA 2AB5A 1N3FA 2O7MA 5A78A 3MXBA 1LWTA 5E67A 5A0WA 4Z1ZA
chains in the Genus database with same CATH superfamily
5A74A 1EF0A 2VBJB 3OORA 4Z20A 4UN9G 2VBLB 3MX9A 1U0DA 3FD2A 4UN9A 5AKNA 3MXAA 1BP7A 1G9ZA 4YITA 5A0MA 1DFAA 3E54A 4UNBA 2VS7A 3HYIA 1M5XA 3C0XA 3KO2A 2DCHX 4YHXA 5AKFA 2CW8A 2I3QA 1VDEA 2VBOB 4KZSA 2F4LA 5E5OA 2XE0B 3C0WA 4AAEA 4AAGA 2VBJA 2VBLA 1DQ3A 1G9YA 2EX5A 2VS8A 2CW7A 4UN8G 2I3PA 3UVFA 4UN8A 2VBNB 1AF5A 4UNAA 3OOLA 4UNCA 4Z1XA 3MXBB 4D6OA 3QQYA 5A72A 1T9IA 1UM2A 1R7MA 1B24A 3R7PA 4AABA 1T9JA 4AQXA 2FLDA 2VBOA 2QOJZ 3MISA 4UT0A 1LWSA 4AAFA 4D6NA 5AKMA 2XE0A 4LOXA 5A77A 4EFJA 4UN7G 3HYJA 1JVAA 4UN7A 4YISA 1MOWA 4LQ0A 3EH8A 5E63A 5AK9A 5A0MB 4AADA 3MIPA 1N3EA 1P8KZ 2VBNA 4AQUA 5E5SA 1U0CA 2AB5A 1N3FA 2O7MA 5A78A 3MXBA 1LWTA 5E67A 5A0WA 4Z1ZA
chains in the Genus database with same CATH topology
5A74A 1EF0A 2VBJB 3OORA 4Z20A 4UN9G 2VBLB 3MX9A 1U0DA 3FD2A 4UN9A 5AKNA 3MXAA 1BP7A 1G9ZA 4YITA 5A0MA 1DFAA 3E54A 4UNBA 2VS7A 3HYIA 1M5XA 3C0XA 3KO2A 2DCHX 4YHXA 5AKFA 2CW8A 2I3QA 1VDEA 2VBOB 5E5OA 2XE0B 3C0WA 4AAEA 4AAGA 2VBJA 2VBLA 1DQ3A 1G9YA 2EX5A 2VS8A 2CW7A 4UN8G 2I3PA 3UVFA 4UN8A 2VBNB 1AF5A 4UNAA 3OOLA 4UNCA 4Z1XA 3MXBB 4D6OA 3QQYA 5A72A 1T9IA 1UM2A 1R7MA 1B24A 3R7PA 4AABA 1T9JA 4AQXA 2FLDA 2VBOA 2QOJZ 3MISA 4UT0A 1LWSA 4AAFA 4D6NA 5AKMA 2XE0A 4LOXA 5A77A 4EFJA 4UN7G 3HYJA 1JVAA 4UN7A 4YISA 1MOWA 4LQ0A 3EH8A 5E63A 5AK9A 5A0MB 4AADA 3MIPA 1N3EA 1P8KZ 2VBNA 4AQUA 5E5SA 1U0CA 2AB5A 1N3FA 2O7MA 5A78A 3MXBA 1LWTA 5E67A 5A0WA 4Z1ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A74 A;  1EF0 A;  2VBJ B;  3OOR A;  4Z20 A;  4UN9 G;  2VBL B;  3MX9 A;  1U0D A;  3FD2 A;  4UN9 A;  5AKN A;  3MXA A;  1BP7 A;  1G9Z A;  4YIT A;  5A0M A;  1DFA A;  3E54 A;  4UNB A;  2VS7 A;  3HYI A;  1M5X A;  3C0X A;  3KO2 A;  2DCH X;  4YHX A;  5AKF A;  2CW8 A;  2I3Q A;  1VDE A;  2VBO B;  5E5O A;  2XE0 B;  3C0W A;  4AAE A;  4AAG A;  2VBJ A;  2VBL A;  1DQ3 A;  1G9Y A;  2EX5 A;  2VS8 A;  2CW7 A;  4UN8 G;  2I3P A;  3UVF A;  4UN8 A;  2VBN B;  1AF5 A;  4UNA A;  3OOL A;  4UNC A;  4Z1X A;  3MXB B;  4D6O A;  3QQY A;  5A72 A;  1T9I A;  1UM2 A;  1R7M A;  1B24 A;  3R7P A;  4AAB A;  1T9J A;  4AQX A;  2FLD A;  2VBO A;  2QOJ Z;  3MIS A;  4UT0 A;  1LWS A;  4AAF A;  4D6N A;  5AKM A;  2XE0 A;  4LOX A;  5A77 A;  4EFJ A;  4UN7 G;  3HYJ A;  1JVA A;  4UN7 A;  4YIS A;  1MOW A;  4LQ0 A;  3EH8 A;  5E63 A;  5AK9 A;  5A0M B;  4AAD A;  3MIP A;  1N3E A;  1P8K Z;  2VBN A;  4AQU A;  5E5S A;  1U0C A;  2AB5 A;  1N3F A;  2O7M A;  5A78 A;  3MXB A;  1LWT A;  5E67 A;  5A0W A;  4Z1Z A; 
#chains in the Genus database with same CATH topology
 5A74 A;  1EF0 A;  2VBJ B;  3OOR A;  4Z20 A;  4UN9 G;  2VBL B;  3MX9 A;  1U0D A;  3FD2 A;  4UN9 A;  5AKN A;  3MXA A;  1BP7 A;  1G9Z A;  4YIT A;  5A0M A;  1DFA A;  3E54 A;  4UNB A;  2VS7 A;  3HYI A;  1M5X A;  3C0X A;  3KO2 A;  2DCH X;  4YHX A;  5AKF A;  2CW8 A;  2I3Q A;  1VDE A;  2VBO B;  4KZS A;  2F4L A;  5E5O A;  2XE0 B;  3C0W A;  4AAE A;  4AAG A;  2VBJ A;  2VBL A;  1DQ3 A;  1G9Y A;  2EX5 A;  2VS8 A;  2CW7 A;  4UN8 G;  2I3P A;  3UVF A;  4UN8 A;  2VBN B;  1AF5 A;  4UNA A;  3OOL A;  4UNC A;  4Z1X A;  3MXB B;  4D6O A;  3QQY A;  5A72 A;  1T9I A;  1UM2 A;  1R7M A;  1B24 A;  3R7P A;  4AAB A;  1T9J A;  4AQX A;  2FLD A;  2VBO A;  2QOJ Z;  3MIS A;  4UT0 A;  1LWS A;  4AAF A;  4D6N A;  5AKM A;  2XE0 A;  4LOX A;  5A77 A;  4EFJ A;  4UN7 G;  3HYJ A;  1JVA A;  4UN7 A;  4YIS A;  1MOW A;  4LQ0 A;  3EH8 A;  5E63 A;  5AK9 A;  5A0M B;  4AAD A;  3MIP A;  1N3E A;  1P8K Z;  2VBN A;  4AQU A;  5E5S A;  1U0C A;  2AB5 A;  1N3F A;  2O7M A;  5A78 A;  3MXB A;  1LWT A;  5E67 A;  5A0W A;  4Z1Z A; 
#chains in the Genus database with same CATH homology
 5A74 A;  1EF0 A;  2VBJ B;  3OOR A;  4Z20 A;  4UN9 G;  2VBL B;  3MX9 A;  1U0D A;  3FD2 A;  4UN9 A;  5AKN A;  3MXA A;  1BP7 A;  1G9Z A;  4YIT A;  5A0M A;  1DFA A;  3E54 A;  4UNB A;  2VS7 A;  3HYI A;  1M5X A;  3C0X A;  3KO2 A;  2DCH X;  4YHX A;  5AKF A;  2CW8 A;  2I3Q A;  1VDE A;  2VBO B;  5E5O A;  2XE0 B;  3C0W A;  4AAE A;  4AAG A;  2VBJ A;  2VBL A;  1DQ3 A;  1G9Y A;  2EX5 A;  2VS8 A;  2CW7 A;  4UN8 G;  2I3P A;  3UVF A;  4UN8 A;  2VBN B;  1AF5 A;  4UNA A;  3OOL A;  4UNC A;  4Z1X A;  3MXB B;  4D6O A;  3QQY A;  5A72 A;  1T9I A;  1UM2 A;  1R7M A;  1B24 A;  3R7P A;  4AAB A;  1T9J A;  4AQX A;  2FLD A;  2VBO A;  2QOJ Z;  3MIS A;  4UT0 A;  1LWS A;  4AAF A;  4D6N A;  5AKM A;  2XE0 A;  4LOX A;  5A77 A;  4EFJ A;  4UN7 G;  3HYJ A;  1JVA A;  4UN7 A;  4YIS A;  1MOW A;  4LQ0 A;  3EH8 A;  5E63 A;  5AK9 A;  5A0M B;  4AAD A;  3MIP A;  1N3E A;  1P8K Z;  2VBN A;  4AQU A;  5E5S A;  1U0C A;  2AB5 A;  1N3F A;  2O7M A;  5A78 A;  3MXB A;  1LWT A;  5E67 A;  5A0W A;  4Z1Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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