4UVOA

Crystal structure of human tankyrase 2 in complex with 5-amino-3-(4- methoxyphenyl)-1,2-dihydroisoquinolin-1-one
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
210
structure length
209
Chain Sequence
GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSAMMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQAYPEYLITYQIMRPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords TANKYRASE-2
total genus 68
structure length 209
sequence length 210
chains with identical sequence B
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2014-08-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00644 PARP Poly(ADP-ribose) polymerase catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 4uvoA00
4LI7A 4J1ZA 3P0PA 2PAXA 4ZZXA 4L31A 3P0QA 5AL2A 5ADSA 1EFYA 4L0IA 4MT9A 5C5RA 3C4HA 2RD6A 4TORA 4L7LA 4X52A 4TK0A 4L2FA 5C5QA 2PAWA 4PNNA 2RF5A 3U9HA 4TK5A 4TVJA 3KCZA 5EBTA 4UW1A 4MSGA 4GV0A 4L0TA 4HLFA 4TKIA 4BJBA 3GN7A 5ECEA 4BUWA 1UK0A 4PNTA 4TKFA 4N4VA 4DQYC 4UNDA 5AL3A 3GJWA 4PY4A 4L2GA 4KZUA 3PAXA 3SMJA 3HKVA 4UUHA 4HKKA 4UVNA 4LI6A 4L7UA 4UHGA 2RCWA 4HKNA 4PNLA 4L70A 4IUEA 5A00A 4TOSA 4UVZA 4K4FA 3U9YA 5DCZA 3W51A 4N3RA 5AL4A 4DVIA 4UVSA 5AL5A 5AL1A 3UA9A 3UH2A 4L09A 4KRSA 4LI8A 4BU3A 3FHBA 4GV7A 3CE0A 4L2KA 4OA7A 4TKGA 4N4TA 5LX6A 4UI3A 3P0NA 3UH4A 4F0EA 4HMHA 4HYFA 5FPGA 5C5PA 5AEHA 4L10A 4UI4A 3SE2A 4BUSA 4BUDA 5FPFA 4UVUA 4K4EA 4OQBC 4F1LA 4UVWA 4U6AA 4HL5A 4F1QA 4UVPA 4BJ9A 3KR8A 4J3MA 4R5WA 3KJDA 4HHZA 4BFPA 4ZZYA 4AVWA 4PNQA 4J3LA 4BUXA 4BS4A 5ADTA 4PJVA 3L3MA 4PNSA 1GS0A 4BU6A 4L34A 4BUAA 4L0SA 4R6EA 4BUUA 4L7RA 4W6EA 5ADQA 4UVTA 4L6ZA 4I9IA 4L7NA 4BUIA 5AKWA 4MSKA 4TJWA 5LYHA 4HLGA 5LXPA 4PMLA 4W5SA 4PJTA 5ADRA 4L32A 4UX4A 4PNRA 3BLJA 4UXBA 4ZZZA 4L0BA 4KZLA 4BUEA 4OQAC 4L33A 4UVVA 4HLHA 3L3LA 4RV6A 4BU7A 4L0VA 4GV4A 4UFUA 1A26A 4UVXA 4W5IA 1UK1A 3MHJA 1WOKA 4BUVA 3GOYA 4M7BA 4UI8A 1PAXA 4HLKA 4UI7A 4UI6A 4BU9A 2X5YA 4BU8A 4L7OA 4PAXA 4HHYA 5AKUA 4HKIA 4AVUA 4OPXC 4L6SA 4UVLA 4L7PA 4UI5A 4J22A 4BUFA 5ETYA 4BJCA 4UFYA 3GEYA 4J21A 4XHUA 4BUYA 4BUTA 4UVYA 3KR7A 4BU5A 4UVOA 2PQFA 3MHKA 3C49A 4HLMA 4PNMA 4KZQA 4TJUA 3SMIA 3UDDA 4TJYA 4GV2A
chains in the Genus database with same CATH superfamily
4LI7A 2FAHA 4J1ZA 3P0PA 2PAXA 5FH0A 4ZZXA 4L31A 3P0QA 5AL2A 2QEYA 4YWBA 5ADSA 1EFYA 4L0IA 4MT9A 5C5RA 2RD6A 3C4HA 3MOHA 4TORA 3DT7A 4L7LA 4X52A 4TK0A 4L2FA 5C5QA 2PAWA 3MOFA 2RF5A 4PNNA 4TK5A 3U9HA 4TVJA 3KCZA 5EBTA 4R43A 4UW1A 4MSGA 1II2A 1M51A 4GV0A 4HLFA 4L0TA 4TKIA 3GN7A 1AYLA 5ECEA 1UK0A 4BUWA 4PNTA 4GNPA 4N4VA 4TKFA 4YWDA 2PY7X 5FH3A 1KHEA 4DQYC 4UNDA 5AL3A 3GJWA 4PY4A 4WPUA 4L2GA 1NHXA 4KZUA 3PAXA 3SMJA 3HKVA 4UUHA 2GMVA 4HKKA 4YW8A 4UVNA 3MOEA 4L7UA 4LI6A 4UHGA 2RCWA 4HKNA 4PNLA 4L70A 4IUEA 5A00A 1J3BA 2RKDA 4K4FA 4TOSA 4UVZA 5DCZA 4N3RA 3U9YA 3W51A 5AL4A 4DVIA 4UVSA 5AL5A 1KHFA 2PXZX 5AL1A 3UA9A 3UH2A 4L09A 4KRSA 4LI8A 4WIUA 4BU3A 3DTBA 3FHBA 2PC9A 4GMWA 4GV7A 3CE0A 4L2KA 4OA7A 1OS1A 2OLQA 1KHGA 4TKGA 4GMUA 4GNMA 4N4TA 3P0NA 4UI3A 5LX6A 2QF1A 3UH4A 5FH2A 4GNQA 3DT2A 3UDDA 4F0EA 4HMHA 4HYFA 5FPGA 5C5PA 3DT4A 5AEHA 1AQ2A 4L10A 4UI4A 1YGGA 3SE2A 4BUSA 4GNOA 4UVUA 4BUDA 4RCGA 4K4EA 5FPFA 4OQBC 4F1LA 4UVWA 4U6AA 4HL5A 5FH4A 4F1QA 4UVPA 4BJ9A 3KR8A 4J3MA 4R5WA 1K3DA 3KJDA 4HHZA 4BFPA 4ZZYA 4AVWA 4PNQA 4J3LA 4BUXA 4BS4A 2RKEA 5ADTA 4PJVA 2OLRA 3L3MA 4PNSA 1YTMA 1GS0A 4BU6A 4L34A 4BUAA 4L0SA 4R6EA 2ZCIA 2FAFA 4WL8A 4L7RA 4W6EA 5FH1A 4BUUA 5ADQA 4UVTA 2RK8A 4L6ZA 2RK7A 4I9IA 4L7NA 4BJBA 4BUIA 5AKWA 1KHBA 4GNLA 4MSKA 4TJWA 5LYHA 4HLGA 5LXPA 2QF2A 4PMLA 4PJTA 4W5SA 2QEWA 1K3CA 5ADRA 4L32A 4UX4A 4PNRA 3BLJA 4UXBA 4ZZZA 4L0BA 4KZLA 4WPVA 4BUEA 4L33A 4UVVA 4OQAC 4HLHA 3L3LA 4RV6A 4BU7A 4L0VA 4GV4A 4GMMA 1A26A 4UFUA 4UVXA 4W5IA 1UK1A 4YW9A 3MHJA 5I67A 1WOKA 4BUVA 3GOYA 4M7BA 4UI8A 1PAXA 4HLKA 4UI7A 4UI6A 4BU9A 2X5YA 4BU8A 4L7OA 4PAXA 4HHYA 5AKUA 4HKIA 1OENA 4AVUA 4GMZA 4L6SA 4UVLA 4L7PA 4UI5A 4WPTA 2QZYA 4OPXC 4J22A 4BUFA 5ETYA 1XKVA 4BJCA 1YVYA 4UFYA 1YLHA 3GEYA 2RKAA 4J21A 4XHUA 4OX2A 4BUYA 4WIEA 4UVYA 3KR7A 4BU5A 4BUTA 4UVOA 2PQFA 3MHKA 3C49A 4HLMA 4PNMA 4KZQA 4TJUA 3SMIA 4WOUA 5FH5A 4TJYA 4GV2A
chains in the Genus database with same CATH topology
4LI7A 2FAHA 4J1ZA 3P0PA 2PAXA 5FH0A 4ZZXA 4L31A 3P0QA 5AL2A 2QEYA 4YWBA 5ADSA 1EFYA 4L0IA 4MT9A 5C5RA 2RD6A 3C4HA 3MOHA 4TORA 3DT7A 4L7LA 4X52A 4TK0A 4L2FA 5C5QA 2PAWA 3MOFA 2RF5A 4PNNA 4TK5A 3U9HA 4TVJA 3KCZA 5EBTA 4R43A 4UW1A 4MSGA 1II2A 1M51A 4GV0A 4HLFA 4L0TA 4TKIA 3GN7A 1AYLA 5ECEA 1UK0A 4BUWA 4PNTA 4GNPA 4N4VA 4TKFA 4YWDA 2PY7X 5FH3A 1KHEA 4DQYC 4UNDA 5AL3A 3GJWA 4PY4A 4WPUA 4L2GA 1NHXA 4KZUA 3PAXA 3SMJA 3HKVA 4UUHA 2GMVA 4HKKA 4YW8A 4UVNA 3MOEA 4L7UA 4LI6A 4UHGA 2RCWA 4HKNA 4PNLA 4L70A 4IUEA 5A00A 1J3BA 2RKDA 4K4FA 4TOSA 4UVZA 5DCZA 4N3RA 3U9YA 3W51A 5AL4A 4DVIA 4UVSA 5AL5A 1KHFA 2PXZX 5AL1A 3UA9A 3UH2A 4L09A 4KRSA 4LI8A 4WIUA 4BU3A 3DTBA 3FHBA 2PC9A 4GMWA 4GV7A 3CE0A 4L2KA 4OA7A 1OS1A 2OLQA 1KHGA 4TKGA 4GMUA 4GNMA 4N4TA 3P0NA 4UI3A 5LX6A 2QF1A 3UH4A 5FH2A 4GNQA 3DT2A 3UDDA 4F0EA 4HMHA 4HYFA 5FPGA 5C5PA 3DT4A 5AEHA 1AQ2A 4L10A 4UI4A 1YGGA 3SE2A 4BUSA 4GNOA 4UVUA 4BUDA 4RCGA 4K4EA 5FPFA 4OQBC 4F1LA 4UVWA 4U6AA 4HL5A 5FH4A 4F1QA 4UVPA 4BJ9A 3KR8A 4J3MA 4R5WA 1K3DA 3KJDA 4HHZA 4BFPA 4ZZYA 4AVWA 4PNQA 4J3LA 4BUXA 4BS4A 2RKEA 5ADTA 4PJVA 2OLRA 3L3MA 4PNSA 1YTMA 1GS0A 4BU6A 4L34A 4BUAA 4L0SA 4R6EA 2ZCIA 2FAFA 4WL8A 4L7RA 4W6EA 5FH1A 4BUUA 5ADQA 4UVTA 2RK8A 4L6ZA 2RK7A 4I9IA 4L7NA 4BJBA 4BUIA 5AKWA 1KHBA 4GNLA 4MSKA 4TJWA 5LYHA 4HLGA 5LXPA 2QF2A 4PMLA 4PJTA 4W5SA 2QEWA 1K3CA 5ADRA 4L32A 4UX4A 4PNRA 3BLJA 4UXBA 4ZZZA 4L0BA 4KZLA 4WPVA 4BUEA 4L33A 4UVVA 4OQAC 4HLHA 3L3LA 4RV6A 4BU7A 4L0VA 4GV4A 4GMMA 1A26A 4UFUA 4UVXA 4W5IA 1UK1A 4YW9A 3MHJA 5I67A 1WOKA 4BUVA 3GOYA 4M7BA 4UI8A 1PAXA 4HLKA 4UI7A 4UI6A 4BU9A 2X5YA 4BU8A 4L7OA 4PAXA 4HHYA 5AKUA 4HKIA 1OENA 4AVUA 4GMZA 4L6SA 4UVLA 4L7PA 4UI5A 4WPTA 2QZYA 4OPXC 4J22A 4BUFA 5ETYA 1XKVA 4BJCA 1YVYA 4UFYA 1YLHA 3GEYA 2RKAA 4J21A 4XHUA 4OX2A 4BUYA 4WIEA 4UVYA 3KR7A 4BU5A 4BUTA 4UVOA 2PQFA 3MHKA 3C49A 4HLMA 4PNMA 4KZQA 4TJUA 3SMIA 4WOUA 5FH5A 4TJYA 4GV2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LI7 A;  4J1Z A;  3P0P A;  2PAX A;  4ZZX A;  4L31 A;  3P0Q A;  5AL2 A;  5ADS A;  1EFY A;  4L0I A;  4MT9 A;  5C5R A;  3C4H A;  2RD6 A;  4TOR A;  4L7L A;  4X52 A;  4TK0 A;  4L2F A;  5C5Q A;  2PAW A;  4PNN A;  2RF5 A;  3U9H A;  4TK5 A;  4TVJ A;  3KCZ A;  5EBT A;  4UW1 A;  4MSG A;  4GV0 A;  4L0T A;  4HLF A;  4TKI A;  4BJB A;  3GN7 A;  5ECE A;  4BUW A;  1UK0 A;  4PNT A;  4TKF A;  4N4V A;  4DQY C;  4UND A;  5AL3 A;  3GJW A;  4PY4 A;  4L2G A;  4KZU A;  3PAX A;  3SMJ A;  3HKV A;  4UUH A;  4HKK A;  4UVN A;  4LI6 A;  4L7U A;  4UHG A;  2RCW A;  4HKN A;  4PNL A;  4L70 A;  4IUE A;  5A00 A;  4TOS A;  4UVZ A;  4K4F A;  3U9Y A;  5DCZ A;  3W51 A;  4N3R A;  5AL4 A;  4DVI A;  4UVS A;  5AL5 A;  5AL1 A;  3UA9 A;  3UH2 A;  4L09 A;  4KRS A;  4LI8 A;  4BU3 A;  3FHB A;  4GV7 A;  3CE0 A;  4L2K A;  4OA7 A;  4TKG A;  4N4T A;  5LX6 A;  4UI3 A;  3P0N A;  3UH4 A;  4F0E A;  4HMH A;  4HYF A;  5FPG A;  5C5P A;  5AEH A;  4L10 A;  4UI4 A;  3SE2 A;  4BUS A;  4BUD A;  5FPF A;  4UVU A;  4K4E A;  4OQB C;  4F1L A;  4UVW A;  4U6A A;  4HL5 A;  4F1Q A;  4UVP A;  4BJ9 A;  3KR8 A;  4J3M A;  4R5W A;  3KJD A;  4HHZ A;  4BFP A;  4ZZY A;  4AVW A;  4PNQ A;  4J3L A;  4BUX A;  4BS4 A;  5ADT A;  4PJV A;  3L3M A;  4PNS A;  1GS0 A;  4BU6 A;  4L34 A;  4BUA A;  4L0S A;  4R6E A;  4BUU A;  4L7R A;  4W6E A;  5ADQ A;  4UVT A;  4L6Z A;  4I9I A;  4L7N A;  4BUI A;  5AKW A;  4MSK A;  4TJW A;  5LYH A;  4HLG A;  5LXP A;  4PML A;  4W5S A;  4PJT A;  5ADR A;  4L32 A;  4UX4 A;  4PNR A;  3BLJ A;  4UXB A;  4ZZZ A;  4L0B A;  4KZL A;  4BUE A;  4OQA C;  4L33 A;  4UVV A;  4HLH A;  3L3L A;  4RV6 A;  4BU7 A;  4L0V A;  4GV4 A;  4UFU A;  1A26 A;  4UVX A;  4W5I A;  1UK1 A;  3MHJ A;  1WOK A;  4BUV A;  3GOY A;  4M7B A;  4UI8 A;  1PAX A;  4HLK A;  4UI7 A;  4UI6 A;  4BU9 A;  2X5Y A;  4BU8 A;  4L7O A;  4PAX A;  4HHY A;  5AKU A;  4HKI A;  4AVU A;  4OPX C;  4L6S A;  4UVL A;  4L7P A;  4UI5 A;  4J22 A;  4BUF A;  5ETY A;  4BJC A;  4UFY A;  3GEY A;  4J21 A;  4XHU A;  4BUY A;  4BUT A;  4UVY A;  3KR7 A;  4BU5 A;  4UVO A;  2PQF A;  3MHK A;  3C49 A;  4HLM A;  4PNM A;  4KZQ A;  4TJU A;  3SMI A;  3UDD A;  4TJY A;  4GV2 A; 
#chains in the Genus database with same CATH topology
 4LI7 A;  2FAH A;  4J1Z A;  3P0P A;  2PAX A;  5FH0 A;  4ZZX A;  4L31 A;  3P0Q A;  5AL2 A;  2QEY A;  4YWB A;  5ADS A;  1EFY A;  4L0I A;  4MT9 A;  5C5R A;  2RD6 A;  3C4H A;  3MOH A;  4TOR A;  3DT7 A;  4L7L A;  4X52 A;  4TK0 A;  4L2F A;  5C5Q A;  2PAW A;  3MOF A;  2RF5 A;  4PNN A;  4TK5 A;  3U9H A;  4TVJ A;  3KCZ A;  5EBT A;  4R43 A;  4UW1 A;  4MSG A;  1II2 A;  1M51 A;  4GV0 A;  4HLF A;  4L0T A;  4TKI A;  3GN7 A;  1AYL A;  5ECE A;  1UK0 A;  4BUW A;  4PNT A;  4GNP A;  4N4V A;  4TKF A;  4YWD A;  2PY7 X;  5FH3 A;  1KHE A;  4DQY C;  4UND A;  5AL3 A;  3GJW A;  4PY4 A;  4WPU A;  4L2G A;  1NHX A;  4KZU A;  3PAX A;  3SMJ A;  3HKV A;  4UUH A;  2GMV A;  4HKK A;  4YW8 A;  4UVN A;  3MOE A;  4L7U A;  4LI6 A;  4UHG A;  2RCW A;  4HKN A;  4PNL A;  4L70 A;  4IUE A;  5A00 A;  1J3B A;  2RKD A;  4K4F A;  4TOS A;  4UVZ A;  5DCZ A;  4N3R A;  3U9Y A;  3W51 A;  5AL4 A;  4DVI A;  4UVS A;  5AL5 A;  1KHF A;  2PXZ X;  5AL1 A;  3UA9 A;  3UH2 A;  4L09 A;  4KRS A;  4LI8 A;  4WIU A;  4BU3 A;  3DTB A;  3FHB A;  2PC9 A;  4GMW A;  4GV7 A;  3CE0 A;  4L2K A;  4OA7 A;  1OS1 A;  2OLQ A;  1KHG A;  4TKG A;  4GMU A;  4GNM A;  4N4T A;  3P0N A;  4UI3 A;  5LX6 A;  2QF1 A;  3UH4 A;  5FH2 A;  4GNQ A;  3DT2 A;  3UDD A;  4F0E A;  4HMH A;  4HYF A;  5FPG A;  5C5P A;  3DT4 A;  5AEH A;  1AQ2 A;  4L10 A;  4UI4 A;  1YGG A;  3SE2 A;  4BUS A;  4GNO A;  4UVU A;  4BUD A;  4RCG A;  4K4E A;  5FPF A;  4OQB C;  4F1L A;  4UVW A;  4U6A A;  4HL5 A;  5FH4 A;  4F1Q A;  4UVP A;  4BJ9 A;  3KR8 A;  4J3M A;  4R5W A;  1K3D A;  3KJD A;  4HHZ A;  4BFP A;  4ZZY A;  4AVW A;  4PNQ A;  4J3L A;  4BUX A;  4BS4 A;  2RKE A;  5ADT A;  4PJV A;  2OLR A;  3L3M A;  4PNS A;  1YTM A;  1GS0 A;  4BU6 A;  4L34 A;  4BUA A;  4L0S A;  4R6E A;  2ZCI A;  2FAF A;  4WL8 A;  4L7R A;  4W6E A;  5FH1 A;  4BUU A;  5ADQ A;  4UVT A;  2RK8 A;  4L6Z A;  2RK7 A;  4I9I A;  4L7N A;  4BJB A;  4BUI A;  5AKW A;  1KHB A;  4GNL A;  4MSK A;  4TJW A;  5LYH A;  4HLG A;  5LXP A;  2QF2 A;  4PML A;  4PJT A;  4W5S A;  2QEW A;  1K3C A;  5ADR A;  4L32 A;  4UX4 A;  4PNR A;  3BLJ A;  4UXB A;  4ZZZ A;  4L0B A;  4KZL A;  4WPV A;  4BUE A;  4L33 A;  4UVV A;  4OQA C;  4HLH A;  3L3L A;  4RV6 A;  4BU7 A;  4L0V A;  4GV4 A;  4GMM A;  1A26 A;  4UFU A;  4UVX A;  4W5I A;  1UK1 A;  4YW9 A;  3MHJ A;  5I67 A;  1WOK A;  4BUV A;  3GOY A;  4M7B A;  4UI8 A;  1PAX A;  4HLK A;  4UI7 A;  4UI6 A;  4BU9 A;  2X5Y A;  4BU8 A;  4L7O A;  4PAX A;  4HHY A;  5AKU A;  4HKI A;  1OEN A;  4AVU A;  4GMZ A;  4L6S A;  4UVL A;  4L7P A;  4UI5 A;  4WPT A;  2QZY A;  4OPX C;  4J22 A;  4BUF A;  5ETY A;  1XKV A;  4BJC A;  1YVY A;  4UFY A;  1YLH A;  3GEY A;  2RKA A;  4J21 A;  4XHU A;  4OX2 A;  4BUY A;  4WIE A;  4UVY A;  3KR7 A;  4BU5 A;  4BUT A;  4UVO A;  2PQF A;  3MHK A;  3C49 A;  4HLM A;  4PNM A;  4KZQ A;  4TJU A;  3SMI A;  4WOU A;  5FH5 A;  4TJY A;  4GV2 A; 
#chains in the Genus database with same CATH homology
 4LI7 A;  2FAH A;  4J1Z A;  3P0P A;  2PAX A;  5FH0 A;  4ZZX A;  4L31 A;  3P0Q A;  5AL2 A;  2QEY A;  4YWB A;  5ADS A;  1EFY A;  4L0I A;  4MT9 A;  5C5R A;  2RD6 A;  3C4H A;  3MOH A;  4TOR A;  3DT7 A;  4L7L A;  4X52 A;  4TK0 A;  4L2F A;  5C5Q A;  2PAW A;  3MOF A;  2RF5 A;  4PNN A;  4TK5 A;  3U9H A;  4TVJ A;  3KCZ A;  5EBT A;  4R43 A;  4UW1 A;  4MSG A;  1II2 A;  1M51 A;  4GV0 A;  4HLF A;  4L0T A;  4TKI A;  3GN7 A;  1AYL A;  5ECE A;  1UK0 A;  4BUW A;  4PNT A;  4GNP A;  4N4V A;  4TKF A;  4YWD A;  2PY7 X;  5FH3 A;  1KHE A;  4DQY C;  4UND A;  5AL3 A;  3GJW A;  4PY4 A;  4WPU A;  4L2G A;  1NHX A;  4KZU A;  3PAX A;  3SMJ A;  3HKV A;  4UUH A;  2GMV A;  4HKK A;  4YW8 A;  4UVN A;  3MOE A;  4L7U A;  4LI6 A;  4UHG A;  2RCW A;  4HKN A;  4PNL A;  4L70 A;  4IUE A;  5A00 A;  1J3B A;  2RKD A;  4K4F A;  4TOS A;  4UVZ A;  5DCZ A;  4N3R A;  3U9Y A;  3W51 A;  5AL4 A;  4DVI A;  4UVS A;  5AL5 A;  1KHF A;  2PXZ X;  5AL1 A;  3UA9 A;  3UH2 A;  4L09 A;  4KRS A;  4LI8 A;  4WIU A;  4BU3 A;  3DTB A;  3FHB A;  2PC9 A;  4GMW A;  4GV7 A;  3CE0 A;  4L2K A;  4OA7 A;  1OS1 A;  2OLQ A;  1KHG A;  4TKG A;  4GMU A;  4GNM A;  4N4T A;  3P0N A;  4UI3 A;  5LX6 A;  2QF1 A;  3UH4 A;  5FH2 A;  4GNQ A;  3DT2 A;  3UDD A;  4F0E A;  4HMH A;  4HYF A;  5FPG A;  5C5P A;  3DT4 A;  5AEH A;  1AQ2 A;  4L10 A;  4UI4 A;  1YGG A;  3SE2 A;  4BUS A;  4GNO A;  4UVU A;  4BUD A;  4RCG A;  4K4E A;  5FPF A;  4OQB C;  4F1L A;  4UVW A;  4U6A A;  4HL5 A;  5FH4 A;  4F1Q A;  4UVP A;  4BJ9 A;  3KR8 A;  4J3M A;  4R5W A;  1K3D A;  3KJD A;  4HHZ A;  4BFP A;  4ZZY A;  4AVW A;  4PNQ A;  4J3L A;  4BUX A;  4BS4 A;  2RKE A;  5ADT A;  4PJV A;  2OLR A;  3L3M A;  4PNS A;  1YTM A;  1GS0 A;  4BU6 A;  4L34 A;  4BUA A;  4L0S A;  4R6E A;  2ZCI A;  2FAF A;  4WL8 A;  4L7R A;  4W6E A;  5FH1 A;  4BUU A;  5ADQ A;  4UVT A;  2RK8 A;  4L6Z A;  2RK7 A;  4I9I A;  4L7N A;  4BJB A;  4BUI A;  5AKW A;  1KHB A;  4GNL A;  4MSK A;  4TJW A;  5LYH A;  4HLG A;  5LXP A;  2QF2 A;  4PML A;  4PJT A;  4W5S A;  2QEW A;  1K3C A;  5ADR A;  4L32 A;  4UX4 A;  4PNR A;  3BLJ A;  4UXB A;  4ZZZ A;  4L0B A;  4KZL A;  4WPV A;  4BUE A;  4L33 A;  4UVV A;  4OQA C;  4HLH A;  3L3L A;  4RV6 A;  4BU7 A;  4L0V A;  4GV4 A;  4GMM A;  1A26 A;  4UFU A;  4UVX A;  4W5I A;  1UK1 A;  4YW9 A;  3MHJ A;  5I67 A;  1WOK A;  4BUV A;  3GOY A;  4M7B A;  4UI8 A;  1PAX A;  4HLK A;  4UI7 A;  4UI6 A;  4BU9 A;  2X5Y A;  4BU8 A;  4L7O A;  4PAX A;  4HHY A;  5AKU A;  4HKI A;  1OEN A;  4AVU A;  4GMZ A;  4L6S A;  4UVL A;  4L7P A;  4UI5 A;  4WPT A;  2QZY A;  4OPX C;  4J22 A;  4BUF A;  5ETY A;  1XKV A;  4BJC A;  1YVY A;  4UFY A;  1YLH A;  3GEY A;  2RKA A;  4J21 A;  4XHU A;  4OX2 A;  4BUY A;  4WIE A;  4UVY A;  3KR7 A;  4BU5 A;  4BUT A;  4UVO A;  2PQF A;  3MHK A;  3C49 A;  4HLM A;  4PNM A;  4KZQ A;  4TJU A;  3SMI A;  4WOU A;  5FH5 A;  4TJY A;  4GV2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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