4YHXA

Crystal structure of laglidadg meganuclease i-gpemi bound to uncleaved dna
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
304
structure length
294
Chain Sequence
NESINPWVLTGFADAEGSFILRIRNNNKSSAGYSTELGFQITLHKKDKSILENIQSTWKVGVIANSGDNAVSLKVTRFEDLRVVLNHFEKYPLITQKLGDYLLFKQAFSVMENKEHLKIEGIKRLVGIKANLNWGLTDELKEAFVASGGENIFNKNIPNSGWLAGFTSGEGCFFVSLIKSKSKLGVQVQLVFSITQHARDRELMDNLVTYLGCGYIKEKKKSEFSWLEFVVTKFSDIKDKIIPVFQENNIIGVKLEDFEDWCKVAKLIEEKKHLTESGLEEIRNIKLNMNKGRV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Grosmannia penicillata
molecule keywords Ribosomal protein 3/homing endonuclease-like fusion protein
total genus 88
structure length 294
sequence length 304
ec nomenclature
pdb deposition date 2015-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yhxA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yhxA02
3EH8A 1R7MA 4D6NA 4UNBA 1P8KZ 2VBNA 4LOXA 2VS8A 1JVAA 3OORA 1T9IA 3C0WA 4Z1ZA 4YHXA 3QQYA 3C0XA 1UM2A 3MXBA 4AADA 3MXBB 1DQ3A 3HYIA 3OOLA 2VBJA 2VBJB 4UNCA 5A77A 4AAFA 5A72A 3MX9A 3MISA 3HYJA 2XE0A 1LWSA 4D6OA 2XE0B 4AAEA 1LWTA 5E5OA 5AKFA 5AKMA 4UNAA 5A0MA 4AABA 5A78A 1DFAA 1G9ZA 5A0MB 4UN9A 2VBLB 2EX5A 4EFJA 5A74A 2VBOA 2DCHX 3FD2A 4YISA 2VBOB 2I3QA 2I3PA 2O7MA 4UT0A 1MOWA 5E67A 2VS7A 1VDEA 1U0CA 1N3EA 1B24A 1N3FA 1AF5A 2FLDA 4UN8A 3MIPA 3MXAA 5A0WA 2VBLA 2CW8A 1U0DA 1EF0A 4UN9G 1BP7A 4AAGA 4AQUA 4UN7A 4UN7G 5E5SA 4Z20A 2VBNB 2CW7A 5AKNA 3E54A 4YITA 1M5XA 4AQXA 5AK9A 3R7PA 2AB5A 1T9JA 4UN8G 1G9YA 4LQ0A 3UVFA 4Z1XA 2QOJZ 3KO2A 5E63A
chains in the Genus database with same CATH superfamily
3EH8A 1R7MA 4D6NA 4UNBA 1P8KZ 2VBNA 4LOXA 2VS8A 1JVAA 3OORA 1T9IA 3C0WA 4Z1ZA 4YHXA 3QQYA 3C0XA 1UM2A 2F4LA 3MXBA 4AADA 3MXBB 1DQ3A 3HYIA 3OOLA 2VBJA 2VBJB 4UNCA 5A77A 4AAFA 5A72A 3MX9A 3MISA 3HYJA 2XE0A 1LWSA 4D6OA 2XE0B 4AAEA 1LWTA 5E5OA 5AKFA 5AKMA 4UNAA 5A0MA 4AABA 5A78A 1DFAA 1G9ZA 5A0MB 4UN9A 2VBLB 2EX5A 4EFJA 5A74A 2VBOA 2DCHX 3FD2A 4YISA 2VBOB 2I3QA 2I3PA 4KZSA 2O7MA 4UT0A 1MOWA 5E67A 2VS7A 1VDEA 1U0CA 1N3EA 1B24A 1N3FA 1AF5A 2FLDA 4UN8A 3MIPA 3MXAA 5A0WA 2VBLA 2CW8A 1U0DA 1EF0A 4UN9G 1BP7A 4AAGA 4AQUA 4UN7A 4UN7G 5E5SA 4Z20A 2VBNB 2CW7A 5AKNA 3E54A 4YITA 1M5XA 4AQXA 5AK9A 3R7PA 2AB5A 1T9JA 4UN8G 1G9YA 4LQ0A 3UVFA 4Z1XA 2QOJZ 3KO2A 5E63A
chains in the Genus database with same CATH topology
3EH8A 1R7MA 4D6NA 4UNBA 1P8KZ 2VBNA 4LOXA 2VS8A 1JVAA 3OORA 1T9IA 3C0WA 4Z1ZA 4YHXA 3QQYA 3C0XA 1UM2A 3MXBA 4AADA 3MXBB 1DQ3A 3HYIA 3OOLA 2VBJA 2VBJB 4UNCA 5A77A 4AAFA 5A72A 3MX9A 3MISA 3HYJA 2XE0A 1LWSA 4D6OA 2XE0B 4AAEA 1LWTA 5E5OA 5AKFA 5AKMA 4UNAA 5A0MA 4AABA 5A78A 1DFAA 1G9ZA 5A0MB 4UN9A 2VBLB 2EX5A 4EFJA 5A74A 2VBOA 2DCHX 3FD2A 4YISA 2VBOB 2I3QA 2I3PA 2O7MA 4UT0A 1MOWA 5E67A 2VS7A 1VDEA 1U0CA 1N3EA 1B24A 1N3FA 1AF5A 2FLDA 4UN8A 3MIPA 3MXAA 5A0WA 2VBLA 2CW8A 1U0DA 1EF0A 4UN9G 1BP7A 4AAGA 4AQUA 4UN7A 4UN7G 5E5SA 4Z20A 2VBNB 2CW7A 5AKNA 3E54A 4YITA 1M5XA 4AQXA 5AK9A 3R7PA 2AB5A 1T9JA 4UN8G 1G9YA 4LQ0A 3UVFA 4Z1XA 2QOJZ 3KO2A 5E63A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EH8 A;  1R7M A;  4D6N A;  4UNB A;  1P8K Z;  2VBN A;  4LOX A;  2VS8 A;  1JVA A;  3OOR A;  1T9I A;  3C0W A;  4Z1Z A;  4YHX A;  3QQY A;  3C0X A;  1UM2 A;  3MXB A;  4AAD A;  3MXB B;  1DQ3 A;  3HYI A;  3OOL A;  2VBJ A;  2VBJ B;  4UNC A;  5A77 A;  4AAF A;  5A72 A;  3MX9 A;  3MIS A;  3HYJ A;  2XE0 A;  1LWS A;  4D6O A;  2XE0 B;  4AAE A;  1LWT A;  5E5O A;  5AKF A;  5AKM A;  4UNA A;  5A0M A;  4AAB A;  5A78 A;  1DFA A;  1G9Z A;  5A0M B;  4UN9 A;  2VBL B;  2EX5 A;  4EFJ A;  5A74 A;  2VBO A;  2DCH X;  3FD2 A;  4YIS A;  2VBO B;  2I3Q A;  2I3P A;  2O7M A;  4UT0 A;  1MOW A;  5E67 A;  2VS7 A;  1VDE A;  1U0C A;  1N3E A;  1B24 A;  1N3F A;  1AF5 A;  2FLD A;  4UN8 A;  3MIP A;  3MXA A;  5A0W A;  2VBL A;  2CW8 A;  1U0D A;  1EF0 A;  4UN9 G;  1BP7 A;  4AAG A;  4AQU A;  4UN7 A;  4UN7 G;  5E5S A;  4Z20 A;  2VBN B;  2CW7 A;  5AKN A;  3E54 A;  4YIT A;  1M5X A;  4AQX A;  5AK9 A;  3R7P A;  2AB5 A;  1T9J A;  4UN8 G;  1G9Y A;  4LQ0 A;  3UVF A;  4Z1X A;  2QOJ Z;  3KO2 A;  5E63 A; 
#chains in the Genus database with same CATH topology
 3EH8 A;  1R7M A;  4D6N A;  4UNB A;  1P8K Z;  2VBN A;  4LOX A;  2VS8 A;  1JVA A;  3OOR A;  1T9I A;  3C0W A;  4Z1Z A;  4YHX A;  3QQY A;  3C0X A;  1UM2 A;  2F4L A;  3MXB A;  4AAD A;  3MXB B;  1DQ3 A;  3HYI A;  3OOL A;  2VBJ A;  2VBJ B;  4UNC A;  5A77 A;  4AAF A;  5A72 A;  3MX9 A;  3MIS A;  3HYJ A;  2XE0 A;  1LWS A;  4D6O A;  2XE0 B;  4AAE A;  1LWT A;  5E5O A;  5AKF A;  5AKM A;  4UNA A;  5A0M A;  4AAB A;  5A78 A;  1DFA A;  1G9Z A;  5A0M B;  4UN9 A;  2VBL B;  2EX5 A;  4EFJ A;  5A74 A;  2VBO A;  2DCH X;  3FD2 A;  4YIS A;  2VBO B;  2I3Q A;  2I3P A;  4KZS A;  2O7M A;  4UT0 A;  1MOW A;  5E67 A;  2VS7 A;  1VDE A;  1U0C A;  1N3E A;  1B24 A;  1N3F A;  1AF5 A;  2FLD A;  4UN8 A;  3MIP A;  3MXA A;  5A0W A;  2VBL A;  2CW8 A;  1U0D A;  1EF0 A;  4UN9 G;  1BP7 A;  4AAG A;  4AQU A;  4UN7 A;  4UN7 G;  5E5S A;  4Z20 A;  2VBN B;  2CW7 A;  5AKN A;  3E54 A;  4YIT A;  1M5X A;  4AQX A;  5AK9 A;  3R7P A;  2AB5 A;  1T9J A;  4UN8 G;  1G9Y A;  4LQ0 A;  3UVF A;  4Z1X A;  2QOJ Z;  3KO2 A;  5E63 A; 
#chains in the Genus database with same CATH homology
 3EH8 A;  1R7M A;  4D6N A;  4UNB A;  1P8K Z;  2VBN A;  4LOX A;  2VS8 A;  1JVA A;  3OOR A;  1T9I A;  3C0W A;  4Z1Z A;  4YHX A;  3QQY A;  3C0X A;  1UM2 A;  3MXB A;  4AAD A;  3MXB B;  1DQ3 A;  3HYI A;  3OOL A;  2VBJ A;  2VBJ B;  4UNC A;  5A77 A;  4AAF A;  5A72 A;  3MX9 A;  3MIS A;  3HYJ A;  2XE0 A;  1LWS A;  4D6O A;  2XE0 B;  4AAE A;  1LWT A;  5E5O A;  5AKF A;  5AKM A;  4UNA A;  5A0M A;  4AAB A;  5A78 A;  1DFA A;  1G9Z A;  5A0M B;  4UN9 A;  2VBL B;  2EX5 A;  4EFJ A;  5A74 A;  2VBO A;  2DCH X;  3FD2 A;  4YIS A;  2VBO B;  2I3Q A;  2I3P A;  2O7M A;  4UT0 A;  1MOW A;  5E67 A;  2VS7 A;  1VDE A;  1U0C A;  1N3E A;  1B24 A;  1N3F A;  1AF5 A;  2FLD A;  4UN8 A;  3MIP A;  3MXA A;  5A0W A;  2VBL A;  2CW8 A;  1U0D A;  1EF0 A;  4UN9 G;  1BP7 A;  4AAG A;  4AQU A;  4UN7 A;  4UN7 G;  5E5S A;  4Z20 A;  2VBN B;  2CW7 A;  5AKN A;  3E54 A;  4YIT A;  1M5X A;  4AQX A;  5AK9 A;  3R7P A;  2AB5 A;  1T9J A;  4UN8 G;  1G9Y A;  4LQ0 A;  3UVF A;  4Z1X A;  2QOJ Z;  3KO2 A;  5E63 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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