4YITA

Crystal structure of laglidadg meganuclease i-aabmi bound to uncleaved dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
286
structure length
272
Chain Sequence
INPWFLTGFIDGEGCFRISVTKWRVQLFFQINLHEKDRALLESIKDYLKVGKIHISGKNLVQYRIQTFDELTILIKHLKEYPLVSKKRADFELFNTAHKLIKNNEHLNKEGINKLVSLKASLNLGLSSLKLAFPNVIATRLNIPDPHWLSGFASAEGCFMVGIAKSSASSTGYQVYLTFILTQHVRDENLMKCLVDYFNWGRLARKRNVYEYQVKFSDVEKLLSFFDKYPILGEKAKDLQDFCSVSDLMKSKTHLTEEGVAKIRKIKEGMNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
pubmed doi rcsb
molecule keywords Meganuclease I-AabMI
molecule tags Hydrolase/dna
source organism Gremmeniella abietina
total genus 60
structure length 272
sequence length 286
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yitA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yitA02
1DFAA 1T9JA 4YISA 5E63A 5E67A 3EH8A 2VS8A 4AAFA 1R7MA 5AK9A 4Z1XA 2VBJB 4YITA 3QQYA 3MX9A 3C0XA 5A0MA 2AB5A 4AAGA 3UVFA 2EX5A 5E5SA 4UN8G 4YHXA 4LOXA 2VBLA 3E54A 4UN9G 4UN8A 4UNAA 5A0MB 4UT0A 4UN7G 4UN9A 5A74A 1LWSA 4AQUA 1VDEA 4AADA 2VBLB 5A77A 4UN7A 3KO2A 2QOJZ 1UM2A 2CW7A 2I3QA 2CW8A 2XE0B 4AAEA 3MIPA 3HYIA 1P8KZ 2VBNA 4Z20A 1EF0A 5E5OA 1MOWA 1G9ZA 1JVAA 3HYJA 3C0WA 4AQXA 4LQ0A 2XE0A 1M5XA 3R7PA 4Z1ZA 1N3FA 4AABA 2VBOA 1G9YA 5AKMA 5AKNA 2VBNB 5A0WA 3FD2A 4EFJA 3MXAA 1U0CA 1DQ3A 2VS7A 5AKFA 2VBOB 3OOLA 1T9IA 4UNCA 5A78A 1B24A 4D6NA 3MXBA 5A72A 3OORA 1AF5A 2I3PA 2O7MA 1N3EA 2DCHX 1BP7A 2FLDA 3MISA 2VBJA 4D6OA 1LWTA 3MXBB 1U0DA 4UNBA
chains in the Genus database with same CATH superfamily
1DFAA 1T9JA 2F4LA 4YISA 5E63A 5E67A 3EH8A 2VS8A 4AAFA 1R7MA 5AK9A 4Z1XA 2VBJB 4YITA 3QQYA 3MX9A 3C0XA 5A0MA 2AB5A 4AAGA 3UVFA 2EX5A 5E5SA 4UN8G 4YHXA 4LOXA 2VBLA 3E54A 4UN9G 4UN8A 4UNAA 5A0MB 4UT0A 4UN7G 4UN9A 5A74A 1LWSA 4AQUA 1VDEA 4AADA 2VBLB 5A77A 4UN7A 3KO2A 2QOJZ 1UM2A 2CW7A 2I3QA 4KZSA 2CW8A 2XE0B 4AAEA 3MIPA 3HYIA 1P8KZ 2VBNA 4Z20A 1EF0A 5E5OA 1MOWA 1G9ZA 1JVAA 3HYJA 3C0WA 4AQXA 4LQ0A 2XE0A 1M5XA 3R7PA 4Z1ZA 1N3FA 4AABA 2VBOA 1G9YA 5AKMA 5AKNA 2VBNB 5A0WA 3FD2A 4EFJA 3MXAA 1U0CA 1DQ3A 2VS7A 5AKFA 2VBOB 3OOLA 1T9IA 4UNCA 5A78A 1B24A 4D6NA 3MXBA 5A72A 3OORA 1AF5A 2I3PA 2O7MA 1N3EA 2DCHX 1BP7A 2FLDA 3MISA 2VBJA 4D6OA 1LWTA 3MXBB 1U0DA 4UNBA
chains in the Genus database with same CATH topology
1DFAA 1T9JA 4YISA 5E63A 5E67A 3EH8A 2VS8A 4AAFA 1R7MA 5AK9A 4Z1XA 2VBJB 4YITA 3QQYA 3MX9A 3C0XA 5A0MA 2AB5A 4AAGA 3UVFA 2EX5A 5E5SA 4UN8G 4YHXA 4LOXA 2VBLA 3E54A 4UN9G 4UN8A 4UNAA 5A0MB 4UT0A 4UN7G 4UN9A 5A74A 1LWSA 4AQUA 1VDEA 4AADA 2VBLB 5A77A 4UN7A 3KO2A 2QOJZ 1UM2A 2CW7A 2I3QA 2CW8A 2XE0B 4AAEA 3MIPA 3HYIA 1P8KZ 2VBNA 4Z20A 1EF0A 5E5OA 1MOWA 1G9ZA 1JVAA 3HYJA 3C0WA 4AQXA 4LQ0A 2XE0A 1M5XA 3R7PA 4Z1ZA 1N3FA 4AABA 2VBOA 1G9YA 5AKMA 5AKNA 2VBNB 5A0WA 3FD2A 4EFJA 3MXAA 1U0CA 1DQ3A 2VS7A 5AKFA 2VBOB 3OOLA 1T9IA 4UNCA 5A78A 1B24A 4D6NA 3MXBA 5A72A 3OORA 1AF5A 2I3PA 2O7MA 1N3EA 2DCHX 1BP7A 2FLDA 3MISA 2VBJA 4D6OA 1LWTA 3MXBB 1U0DA 4UNBA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1DFA A;  1T9J A;  4YIS A;  5E63 A;  5E67 A;  3EH8 A;  2VS8 A;  4AAF A;  1R7M A;  5AK9 A;  4Z1X A;  2VBJ B;  4YIT A;  3QQY A;  3MX9 A;  3C0X A;  5A0M A;  2AB5 A;  4AAG A;  3UVF A;  2EX5 A;  5E5S A;  4UN8 G;  4YHX A;  4LOX A;  2VBL A;  3E54 A;  4UN9 G;  4UN8 A;  4UNA A;  5A0M B;  4UT0 A;  4UN7 G;  4UN9 A;  5A74 A;  1LWS A;  4AQU A;  1VDE A;  4AAD A;  2VBL B;  5A77 A;  4UN7 A;  3KO2 A;  2QOJ Z;  1UM2 A;  2CW7 A;  2I3Q A;  2CW8 A;  2XE0 B;  4AAE A;  3MIP A;  3HYI A;  1P8K Z;  2VBN A;  4Z20 A;  1EF0 A;  5E5O A;  1MOW A;  1G9Z A;  1JVA A;  3HYJ A;  3C0W A;  4AQX A;  4LQ0 A;  2XE0 A;  1M5X A;  3R7P A;  4Z1Z A;  1N3F A;  4AAB A;  2VBO A;  1G9Y A;  5AKM A;  5AKN A;  2VBN B;  5A0W A;  3FD2 A;  4EFJ A;  3MXA A;  1U0C A;  1DQ3 A;  2VS7 A;  5AKF A;  2VBO B;  3OOL A;  1T9I A;  4UNC A;  5A78 A;  1B24 A;  4D6N A;  3MXB A;  5A72 A;  3OOR A;  1AF5 A;  2I3P A;  2O7M A;  1N3E A;  2DCH X;  1BP7 A;  2FLD A;  3MIS A;  2VBJ A;  4D6O A;  1LWT A;  3MXB B;  1U0D A;  4UNB A; 
#chains in the Genus database with same CATH topology
 1DFA A;  1T9J A;  2F4L A;  4YIS A;  5E63 A;  5E67 A;  3EH8 A;  2VS8 A;  4AAF A;  1R7M A;  5AK9 A;  4Z1X A;  2VBJ B;  4YIT A;  3QQY A;  3MX9 A;  3C0X A;  5A0M A;  2AB5 A;  4AAG A;  3UVF A;  2EX5 A;  5E5S A;  4UN8 G;  4YHX A;  4LOX A;  2VBL A;  3E54 A;  4UN9 G;  4UN8 A;  4UNA A;  5A0M B;  4UT0 A;  4UN7 G;  4UN9 A;  5A74 A;  1LWS A;  4AQU A;  1VDE A;  4AAD A;  2VBL B;  5A77 A;  4UN7 A;  3KO2 A;  2QOJ Z;  1UM2 A;  2CW7 A;  2I3Q A;  4KZS A;  2CW8 A;  2XE0 B;  4AAE A;  3MIP A;  3HYI A;  1P8K Z;  2VBN A;  4Z20 A;  1EF0 A;  5E5O A;  1MOW A;  1G9Z A;  1JVA A;  3HYJ A;  3C0W A;  4AQX A;  4LQ0 A;  2XE0 A;  1M5X A;  3R7P A;  4Z1Z A;  1N3F A;  4AAB A;  2VBO A;  1G9Y A;  5AKM A;  5AKN A;  2VBN B;  5A0W A;  3FD2 A;  4EFJ A;  3MXA A;  1U0C A;  1DQ3 A;  2VS7 A;  5AKF A;  2VBO B;  3OOL A;  1T9I A;  4UNC A;  5A78 A;  1B24 A;  4D6N A;  3MXB A;  5A72 A;  3OOR A;  1AF5 A;  2I3P A;  2O7M A;  1N3E A;  2DCH X;  1BP7 A;  2FLD A;  3MIS A;  2VBJ A;  4D6O A;  1LWT A;  3MXB B;  1U0D A;  4UNB A; 
#chains in the Genus database with same CATH homology
 1DFA A;  1T9J A;  4YIS A;  5E63 A;  5E67 A;  3EH8 A;  2VS8 A;  4AAF A;  1R7M A;  5AK9 A;  4Z1X A;  2VBJ B;  4YIT A;  3QQY A;  3MX9 A;  3C0X A;  5A0M A;  2AB5 A;  4AAG A;  3UVF A;  2EX5 A;  5E5S A;  4UN8 G;  4YHX A;  4LOX A;  2VBL A;  3E54 A;  4UN9 G;  4UN8 A;  4UNA A;  5A0M B;  4UT0 A;  4UN7 G;  4UN9 A;  5A74 A;  1LWS A;  4AQU A;  1VDE A;  4AAD A;  2VBL B;  5A77 A;  4UN7 A;  3KO2 A;  2QOJ Z;  1UM2 A;  2CW7 A;  2I3Q A;  2CW8 A;  2XE0 B;  4AAE A;  3MIP A;  3HYI A;  1P8K Z;  2VBN A;  4Z20 A;  1EF0 A;  5E5O A;  1MOW A;  1G9Z A;  1JVA A;  3HYJ A;  3C0W A;  4AQX A;  4LQ0 A;  2XE0 A;  1M5X A;  3R7P A;  4Z1Z A;  1N3F A;  4AAB A;  2VBO A;  1G9Y A;  5AKM A;  5AKN A;  2VBN B;  5A0W A;  3FD2 A;  4EFJ A;  3MXA A;  1U0C A;  1DQ3 A;  2VS7 A;  5AKF A;  2VBO B;  3OOL A;  1T9I A;  4UNC A;  5A78 A;  1B24 A;  4D6N A;  3MXB A;  5A72 A;  3OOR A;  1AF5 A;  2I3P A;  2O7M A;  1N3E A;  2DCH X;  1BP7 A;  2FLD A;  3MIS A;  2VBJ A;  4D6O A;  1LWT A;  3MXB B;  1U0D A;  4UNB A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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