4YITA

Crystal structure of laglidadg meganuclease i-aabmi bound to uncleaved dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
286
structure length
272
Chain Sequence
INPWFLTGFIDGEGCFRISVTKWRVQLFFQINLHEKDRALLESIKDYLKVGKIHISGKNLVQYRIQTFDELTILIKHLKEYPLVSKKRADFELFNTAHKLIKNNEHLNKEGINKLVSLKASLNLGLSSLKLAFPNVIATRLNIPDPHWLSGFASAEGCFMVGIAKSSASSTGYQVYLTFILTQHVRDENLMKCLVDYFNWGRLARKRNVYEYQVKFSDVEKLLSFFDKYPILGEKAKDLQDFCSVSDLMKSKTHLTEEGVAKIRKIKEGMNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Gremmeniella abietina
molecule keywords Meganuclease I-AabMI
total genus 60
structure length 272
sequence length 286
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yitA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yitA02
2FLDA 1R7MA 1UM2A 2VS7A 2CW7A 1B24A 4Z1ZA 5A78A 3KO2A 1DFAA 4YISA 1LWTA 3C0XA 2CW8A 2O7MA 3FD2A 4UNAA 4UN9G 2XE0A 1AF5A 4D6NA 2VBJA 3HYJA 4UT0A 4AAFA 4Z1XA 4AQUA 5A74A 2XE0B 3EH8A 2VBJB 3R7PA 5E5OA 4AADA 1DQ3A 2VBNA 1U0CA 2QOJZ 1U0DA 2EX5A 1T9IA 1EF0A 5A0WA 3UVFA 4UN7G 4UN9A 5AKFA 1MOWA 2AB5A 4D6OA 4UN8A 4YHXA 2VBNB 5A0MB 2DCHX 3OORA 1T9JA 2VBLA 4Z20A 4LQ0A 4AQXA 4EFJA 2VS8A 5AKNA 2I3QA 3MX9A 5E63A 1N3EA 5A77A 5E67A 5A0MA 4UNBA 3MISA 3C0WA 2VBLB 3E54A 3MIPA 3QQYA 3HYIA 4AABA 4YITA 5A72A 4UNCA 5AKMA 1JVAA 1BP7A 3MXAA 4UN7A 4LOXA 2VBOA 1N3FA 3MXBA 1G9YA 4AAGA 1LWSA 1M5XA 4AAEA 2I3PA 1P8KZ 4UN8G 2VBOB 5E5SA 3MXBB 5AK9A 1VDEA 1G9ZA 3OOLA
chains in the Genus database with same CATH superfamily
2FLDA 1R7MA 1UM2A 2VS7A 2CW7A 1B24A 4Z1ZA 5A78A 3KO2A 1DFAA 4YISA 1LWTA 3C0XA 2CW8A 2O7MA 3FD2A 4UNAA 4UN9G 2XE0A 1AF5A 4D6NA 2VBJA 3HYJA 4UT0A 4AAFA 4Z1XA 4AQUA 5A74A 2XE0B 4KZSA 3EH8A 2VBJB 3R7PA 5E5OA 4AADA 1DQ3A 2VBNA 1U0CA 2QOJZ 1U0DA 2EX5A 1T9IA 1EF0A 5A0WA 3UVFA 4UN7G 4UN9A 5AKFA 1MOWA 2AB5A 4D6OA 4UN8A 4YHXA 2VBNB 5A0MB 2DCHX 3OORA 1T9JA 2VBLA 4Z20A 4LQ0A 4AQXA 4EFJA 2VS8A 5AKNA 2I3QA 3MX9A 5E63A 1N3EA 5A77A 5E67A 5A0MA 4UNBA 3MISA 3C0WA 2VBLB 3E54A 3MIPA 3QQYA 3HYIA 4AABA 4YITA 5A72A 4UNCA 5AKMA 1JVAA 1BP7A 3MXAA 4UN7A 4LOXA 2VBOA 1N3FA 3MXBA 1G9YA 4AAGA 1LWSA 1M5XA 4AAEA 2F4LA 2I3PA 1P8KZ 4UN8G 2VBOB 5E5SA 3MXBB 5AK9A 1VDEA 1G9ZA 3OOLA
chains in the Genus database with same CATH topology
2FLDA 1R7MA 1UM2A 2VS7A 2CW7A 1B24A 4Z1ZA 5A78A 3KO2A 1DFAA 4YISA 1LWTA 3C0XA 2CW8A 2O7MA 3FD2A 4UNAA 4UN9G 2XE0A 1AF5A 4D6NA 2VBJA 3HYJA 4UT0A 4AAFA 4Z1XA 4AQUA 5A74A 2XE0B 3EH8A 2VBJB 3R7PA 5E5OA 4AADA 1DQ3A 2VBNA 1U0CA 2QOJZ 1U0DA 2EX5A 1T9IA 1EF0A 5A0WA 3UVFA 4UN7G 4UN9A 5AKFA 1MOWA 2AB5A 4D6OA 4UN8A 4YHXA 2VBNB 5A0MB 2DCHX 3OORA 1T9JA 2VBLA 4Z20A 4LQ0A 4AQXA 4EFJA 2VS8A 5AKNA 2I3QA 3MX9A 5E63A 1N3EA 5A77A 5E67A 5A0MA 4UNBA 3MISA 3C0WA 2VBLB 3E54A 3MIPA 3QQYA 3HYIA 4AABA 4YITA 5A72A 4UNCA 5AKMA 1JVAA 1BP7A 3MXAA 4UN7A 4LOXA 2VBOA 1N3FA 3MXBA 1G9YA 4AAGA 1LWSA 1M5XA 4AAEA 2I3PA 1P8KZ 4UN8G 2VBOB 5E5SA 3MXBB 5AK9A 1VDEA 1G9ZA 3OOLA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2FLD A;  1R7M A;  1UM2 A;  2VS7 A;  2CW7 A;  1B24 A;  4Z1Z A;  5A78 A;  3KO2 A;  1DFA A;  4YIS A;  1LWT A;  3C0X A;  2CW8 A;  2O7M A;  3FD2 A;  4UNA A;  4UN9 G;  2XE0 A;  1AF5 A;  4D6N A;  2VBJ A;  3HYJ A;  4UT0 A;  4AAF A;  4Z1X A;  4AQU A;  5A74 A;  2XE0 B;  3EH8 A;  2VBJ B;  3R7P A;  5E5O A;  4AAD A;  1DQ3 A;  2VBN A;  1U0C A;  2QOJ Z;  1U0D A;  2EX5 A;  1T9I A;  1EF0 A;  5A0W A;  3UVF A;  4UN7 G;  4UN9 A;  5AKF A;  1MOW A;  2AB5 A;  4D6O A;  4UN8 A;  4YHX A;  2VBN B;  5A0M B;  2DCH X;  3OOR A;  1T9J A;  2VBL A;  4Z20 A;  4LQ0 A;  4AQX A;  4EFJ A;  2VS8 A;  5AKN A;  2I3Q A;  3MX9 A;  5E63 A;  1N3E A;  5A77 A;  5E67 A;  5A0M A;  4UNB A;  3MIS A;  3C0W A;  2VBL B;  3E54 A;  3MIP A;  3QQY A;  3HYI A;  4AAB A;  4YIT A;  5A72 A;  4UNC A;  5AKM A;  1JVA A;  1BP7 A;  3MXA A;  4UN7 A;  4LOX A;  2VBO A;  1N3F A;  3MXB A;  1G9Y A;  4AAG A;  1LWS A;  1M5X A;  4AAE A;  2I3P A;  1P8K Z;  4UN8 G;  2VBO B;  5E5S A;  3MXB B;  5AK9 A;  1VDE A;  1G9Z A;  3OOL A; 
#chains in the Genus database with same CATH topology
 2FLD A;  1R7M A;  1UM2 A;  2VS7 A;  2CW7 A;  1B24 A;  4Z1Z A;  5A78 A;  3KO2 A;  1DFA A;  4YIS A;  1LWT A;  3C0X A;  2CW8 A;  2O7M A;  3FD2 A;  4UNA A;  4UN9 G;  2XE0 A;  1AF5 A;  4D6N A;  2VBJ A;  3HYJ A;  4UT0 A;  4AAF A;  4Z1X A;  4AQU A;  5A74 A;  2XE0 B;  4KZS A;  3EH8 A;  2VBJ B;  3R7P A;  5E5O A;  4AAD A;  1DQ3 A;  2VBN A;  1U0C A;  2QOJ Z;  1U0D A;  2EX5 A;  1T9I A;  1EF0 A;  5A0W A;  3UVF A;  4UN7 G;  4UN9 A;  5AKF A;  1MOW A;  2AB5 A;  4D6O A;  4UN8 A;  4YHX A;  2VBN B;  5A0M B;  2DCH X;  3OOR A;  1T9J A;  2VBL A;  4Z20 A;  4LQ0 A;  4AQX A;  4EFJ A;  2VS8 A;  5AKN A;  2I3Q A;  3MX9 A;  5E63 A;  1N3E A;  5A77 A;  5E67 A;  5A0M A;  4UNB A;  3MIS A;  3C0W A;  2VBL B;  3E54 A;  3MIP A;  3QQY A;  3HYI A;  4AAB A;  4YIT A;  5A72 A;  4UNC A;  5AKM A;  1JVA A;  1BP7 A;  3MXA A;  4UN7 A;  4LOX A;  2VBO A;  1N3F A;  3MXB A;  1G9Y A;  4AAG A;  1LWS A;  1M5X A;  4AAE A;  2F4L A;  2I3P A;  1P8K Z;  4UN8 G;  2VBO B;  5E5S A;  3MXB B;  5AK9 A;  1VDE A;  1G9Z A;  3OOL A; 
#chains in the Genus database with same CATH homology
 2FLD A;  1R7M A;  1UM2 A;  2VS7 A;  2CW7 A;  1B24 A;  4Z1Z A;  5A78 A;  3KO2 A;  1DFA A;  4YIS A;  1LWT A;  3C0X A;  2CW8 A;  2O7M A;  3FD2 A;  4UNA A;  4UN9 G;  2XE0 A;  1AF5 A;  4D6N A;  2VBJ A;  3HYJ A;  4UT0 A;  4AAF A;  4Z1X A;  4AQU A;  5A74 A;  2XE0 B;  3EH8 A;  2VBJ B;  3R7P A;  5E5O A;  4AAD A;  1DQ3 A;  2VBN A;  1U0C A;  2QOJ Z;  1U0D A;  2EX5 A;  1T9I A;  1EF0 A;  5A0W A;  3UVF A;  4UN7 G;  4UN9 A;  5AKF A;  1MOW A;  2AB5 A;  4D6O A;  4UN8 A;  4YHX A;  2VBN B;  5A0M B;  2DCH X;  3OOR A;  1T9J A;  2VBL A;  4Z20 A;  4LQ0 A;  4AQX A;  4EFJ A;  2VS8 A;  5AKN A;  2I3Q A;  3MX9 A;  5E63 A;  1N3E A;  5A77 A;  5E67 A;  5A0M A;  4UNB A;  3MIS A;  3C0W A;  2VBL B;  3E54 A;  3MIP A;  3QQY A;  3HYI A;  4AAB A;  4YIT A;  5A72 A;  4UNC A;  5AKM A;  1JVA A;  1BP7 A;  3MXA A;  4UN7 A;  4LOX A;  2VBO A;  1N3F A;  3MXB A;  1G9Y A;  4AAG A;  1LWS A;  1M5X A;  4AAE A;  2I3P A;  1P8K Z;  4UN8 G;  2VBO B;  5E5S A;  3MXB B;  5AK9 A;  1VDE A;  1G9Z A;  3OOL A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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