4YITA

Crystal structure of laglidadg meganuclease i-aabmi bound to uncleaved dna
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
286
structure length
272
Chain Sequence
INPWFLTGFIDGEGCFRISVTKWRVQLFFQINLHEKDRALLESIKDYLKVGKIHISGKNLVQYRIQTFDELTILIKHLKEYPLVSKKRADFELFNTAHKLIKNNEHLNKEGINKLVSLKASLNLGLSSLKLAFPNVIATRLNIPDPHWLSGFASAEGCFMVGIAKSSASSTGYQVYLTFILTQHVRDENLMKCLVDYFNWGRLARKRNVYEYQVKFSDVEKLLSFFDKYPILGEKAKDLQDFCSVSDLMKSKTHLTEEGVAKIRKIKEGMNR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase/dna
source organism Gremmeniella abietina
publication title Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
pubmed doi rcsb
molecule keywords Meganuclease I-AabMI
total genus 60
structure length 272
sequence length 286
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yitA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4yitA02
2VBNA 5A0WA 2VBJA 1UM2A 5A0MB 2VBLA 4UN9A 5A74A 5A0MA 4Z1XA 1G9ZA 1U0CA 3HYJA 4YISA 4AAGA 4UN7G 3MXAA 1LWSA 1JVAA 4EFJA 4UT0A 1R7MA 5AKNA 2XE0B 3OOLA 2I3PA 4YHXA 5E5SA 5A72A 1T9IA 4AABA 1N3EA 3FD2A 4AADA 4LQ0A 4AAEA 4UN7A 3UVFA 2VS7A 4YITA 3HYIA 2AB5A 4Z20A 1DQ3A 3QQYA 3MISA 4Z1ZA 2XE0A 2EX5A 3OORA 2DCHX 2O7MA 1U0DA 2VBOB 3KO2A 4AQXA 2VBOA 5E63A 5A78A 1T9JA 1VDEA 2VS8A 1DFAA 2I3QA 3EH8A 4D6OA 4D6NA 5E5OA 4UN8G 3C0XA 2QOJZ 1MOWA 2CW8A 1B24A 3MX9A 4UNCA 1AF5A 5A77A 2VBJB 1G9YA 1EF0A 2CW7A 2VBLB 4AQUA 5E67A 4UN9G 5AK9A 3MXBB 4AAFA 3MXBA 1P8KZ 5AKMA 3R7PA 4LOXA 1LWTA 4UNAA 4UN8A 1BP7A 4UNBA 3MIPA 3C0WA 3E54A 1N3FA 5AKFA 2VBNB 2FLDA 1M5XA
chains in the Genus database with same CATH superfamily
2VBNA 5A0WA 2VBJA 1UM2A 5A0MB 2VBLA 4UN9A 5A74A 5A0MA 4Z1XA 1G9ZA 1U0CA 3HYJA 4YISA 4AAGA 4UN7G 3MXAA 1LWSA 2F4LA 1JVAA 4EFJA 4UT0A 1R7MA 5AKNA 2XE0B 3OOLA 2I3PA 4YHXA 5E5SA 5A72A 1T9IA 4AABA 1N3EA 3FD2A 4AADA 4LQ0A 4AAEA 4UN7A 3UVFA 2VS7A 4YITA 3HYIA 2AB5A 4Z20A 1DQ3A 3QQYA 3MISA 4Z1ZA 2XE0A 2EX5A 3OORA 2DCHX 2O7MA 1U0DA 2VBOB 3KO2A 4AQXA 2VBOA 5E63A 5A78A 1T9JA 1VDEA 2VS8A 1DFAA 2I3QA 3EH8A 4D6OA 4D6NA 5E5OA 4UN8G 3C0XA 2QOJZ 1MOWA 2CW8A 1B24A 3MX9A 4UNCA 1AF5A 5A77A 2VBJB 1G9YA 1EF0A 2CW7A 2VBLB 4AQUA 5E67A 4UN9G 5AK9A 3MXBB 4AAFA 3MXBA 1P8KZ 5AKMA 3R7PA 4LOXA 1LWTA 4UNAA 4UN8A 1BP7A 4UNBA 3MIPA 3C0WA 4KZSA 3E54A 1N3FA 5AKFA 2VBNB 2FLDA 1M5XA
chains in the Genus database with same CATH topology
2VBNA 5A0WA 2VBJA 1UM2A 5A0MB 2VBLA 4UN9A 5A74A 5A0MA 4Z1XA 1G9ZA 1U0CA 3HYJA 4YISA 4AAGA 4UN7G 3MXAA 1LWSA 1JVAA 4EFJA 4UT0A 1R7MA 5AKNA 2XE0B 3OOLA 2I3PA 4YHXA 5E5SA 5A72A 1T9IA 4AABA 1N3EA 3FD2A 4AADA 4LQ0A 4AAEA 4UN7A 3UVFA 2VS7A 4YITA 3HYIA 2AB5A 4Z20A 1DQ3A 3QQYA 3MISA 4Z1ZA 2XE0A 2EX5A 3OORA 2DCHX 2O7MA 1U0DA 2VBOB 3KO2A 4AQXA 2VBOA 5E63A 5A78A 1T9JA 1VDEA 2VS8A 1DFAA 2I3QA 3EH8A 4D6OA 4D6NA 5E5OA 4UN8G 3C0XA 2QOJZ 1MOWA 2CW8A 1B24A 3MX9A 4UNCA 1AF5A 5A77A 2VBJB 1G9YA 1EF0A 2CW7A 2VBLB 4AQUA 5E67A 4UN9G 5AK9A 3MXBB 4AAFA 3MXBA 1P8KZ 5AKMA 3R7PA 4LOXA 1LWTA 4UNAA 4UN8A 1BP7A 4UNBA 3MIPA 3C0WA 3E54A 1N3FA 5AKFA 2VBNB 2FLDA 1M5XA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2VBN A;  5A0W A;  2VBJ A;  1UM2 A;  5A0M B;  2VBL A;  4UN9 A;  5A74 A;  5A0M A;  4Z1X A;  1G9Z A;  1U0C A;  3HYJ A;  4YIS A;  4AAG A;  4UN7 G;  3MXA A;  1LWS A;  1JVA A;  4EFJ A;  4UT0 A;  1R7M A;  5AKN A;  2XE0 B;  3OOL A;  2I3P A;  4YHX A;  5E5S A;  5A72 A;  1T9I A;  4AAB A;  1N3E A;  3FD2 A;  4AAD A;  4LQ0 A;  4AAE A;  4UN7 A;  3UVF A;  2VS7 A;  4YIT A;  3HYI A;  2AB5 A;  4Z20 A;  1DQ3 A;  3QQY A;  3MIS A;  4Z1Z A;  2XE0 A;  2EX5 A;  3OOR A;  2DCH X;  2O7M A;  1U0D A;  2VBO B;  3KO2 A;  4AQX A;  2VBO A;  5E63 A;  5A78 A;  1T9J A;  1VDE A;  2VS8 A;  1DFA A;  2I3Q A;  3EH8 A;  4D6O A;  4D6N A;  5E5O A;  4UN8 G;  3C0X A;  2QOJ Z;  1MOW A;  2CW8 A;  1B24 A;  3MX9 A;  4UNC A;  1AF5 A;  5A77 A;  2VBJ B;  1G9Y A;  1EF0 A;  2CW7 A;  2VBL B;  4AQU A;  5E67 A;  4UN9 G;  5AK9 A;  3MXB B;  4AAF A;  3MXB A;  1P8K Z;  5AKM A;  3R7P A;  4LOX A;  1LWT A;  4UNA A;  4UN8 A;  1BP7 A;  4UNB A;  3MIP A;  3C0W A;  3E54 A;  1N3F A;  5AKF A;  2VBN B;  2FLD A;  1M5X A; 
#chains in the Genus database with same CATH topology
 2VBN A;  5A0W A;  2VBJ A;  1UM2 A;  5A0M B;  2VBL A;  4UN9 A;  5A74 A;  5A0M A;  4Z1X A;  1G9Z A;  1U0C A;  3HYJ A;  4YIS A;  4AAG A;  4UN7 G;  3MXA A;  1LWS A;  2F4L A;  1JVA A;  4EFJ A;  4UT0 A;  1R7M A;  5AKN A;  2XE0 B;  3OOL A;  2I3P A;  4YHX A;  5E5S A;  5A72 A;  1T9I A;  4AAB A;  1N3E A;  3FD2 A;  4AAD A;  4LQ0 A;  4AAE A;  4UN7 A;  3UVF A;  2VS7 A;  4YIT A;  3HYI A;  2AB5 A;  4Z20 A;  1DQ3 A;  3QQY A;  3MIS A;  4Z1Z A;  2XE0 A;  2EX5 A;  3OOR A;  2DCH X;  2O7M A;  1U0D A;  2VBO B;  3KO2 A;  4AQX A;  2VBO A;  5E63 A;  5A78 A;  1T9J A;  1VDE A;  2VS8 A;  1DFA A;  2I3Q A;  3EH8 A;  4D6O A;  4D6N A;  5E5O A;  4UN8 G;  3C0X A;  2QOJ Z;  1MOW A;  2CW8 A;  1B24 A;  3MX9 A;  4UNC A;  1AF5 A;  5A77 A;  2VBJ B;  1G9Y A;  1EF0 A;  2CW7 A;  2VBL B;  4AQU A;  5E67 A;  4UN9 G;  5AK9 A;  3MXB B;  4AAF A;  3MXB A;  1P8K Z;  5AKM A;  3R7P A;  4LOX A;  1LWT A;  4UNA A;  4UN8 A;  1BP7 A;  4UNB A;  3MIP A;  3C0W A;  4KZS A;  3E54 A;  1N3F A;  5AKF A;  2VBN B;  2FLD A;  1M5X A; 
#chains in the Genus database with same CATH homology
 2VBN A;  5A0W A;  2VBJ A;  1UM2 A;  5A0M B;  2VBL A;  4UN9 A;  5A74 A;  5A0M A;  4Z1X A;  1G9Z A;  1U0C A;  3HYJ A;  4YIS A;  4AAG A;  4UN7 G;  3MXA A;  1LWS A;  1JVA A;  4EFJ A;  4UT0 A;  1R7M A;  5AKN A;  2XE0 B;  3OOL A;  2I3P A;  4YHX A;  5E5S A;  5A72 A;  1T9I A;  4AAB A;  1N3E A;  3FD2 A;  4AAD A;  4LQ0 A;  4AAE A;  4UN7 A;  3UVF A;  2VS7 A;  4YIT A;  3HYI A;  2AB5 A;  4Z20 A;  1DQ3 A;  3QQY A;  3MIS A;  4Z1Z A;  2XE0 A;  2EX5 A;  3OOR A;  2DCH X;  2O7M A;  1U0D A;  2VBO B;  3KO2 A;  4AQX A;  2VBO A;  5E63 A;  5A78 A;  1T9J A;  1VDE A;  2VS8 A;  1DFA A;  2I3Q A;  3EH8 A;  4D6O A;  4D6N A;  5E5O A;  4UN8 G;  3C0X A;  2QOJ Z;  1MOW A;  2CW8 A;  1B24 A;  3MX9 A;  4UNC A;  1AF5 A;  5A77 A;  2VBJ B;  1G9Y A;  1EF0 A;  2CW7 A;  2VBL B;  4AQU A;  5E67 A;  4UN9 G;  5AK9 A;  3MXB B;  4AAF A;  3MXB A;  1P8K Z;  5AKM A;  3R7P A;  4LOX A;  1LWT A;  4UNA A;  4UN8 A;  1BP7 A;  4UNB A;  3MIP A;  3C0W A;  3E54 A;  1N3F A;  5AKF A;  2VBN B;  2FLD A;  1M5X A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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