4Z20A

Crystal structure of meganuclease i-smami bound to uncleaveable dna with a ttgt central four
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
300
structure length
298
Chain Sequence
GENSKLNPWAVVGFIDAEGSFMVRVRKNSKYKTGWLVVAIFSVTVDKKDLFLLESLKTFFGGLGSIKKSGNSTFSYRIESSEQLTKIILPFFDKYSLITEKLGDYLLFKKVLELMGTKEHLTQRGLEKIVSLKASINKGLSEELQAAFPQCVPTPRPNNKNIPDPFWLAGFVSGDGSFKSILKKSESIKVGFQSILVFQITQHARDVKLMESLISYLGCGFIEKDSRGPWLYYTVTNFSDIQGKIIPFFHQYKIIGSKYGDYQDWCKIALIMQNKNHLTPEGLNEIRALKGGMNKGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Sordaria macrospora (strain atcc mya-333 / dsm 997 / k(l3346) / k-hell)
molecule keywords MEGANUCLEASE I-SMAMI
total genus 84
structure length 298
sequence length 300
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4z20A01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4z20A02
3EH8A 5AKFA 4AADA 4AABA 1B24A 4Z1XA 2I3PA 5A78A 3MXBB 3OORA 1G9ZA 2O7MA 2VBJA 1EF0A 4UN8G 4UN9A 3MXAA 2FLDA 2VBNB 4Z20A 5A77A 4UN7G 3C0WA 4EFJA 1U0DA 1P8KZ 4UT0A 2QOJZ 2CW8A 3UVFA 2VBJB 4D6NA 4Z1ZA 4YISA 1UM2A 2EX5A 5E63A 5A74A 1DFAA 2AB5A 3OOLA 4AQUA 4LQ0A 1N3EA 4YHXA 2VBLA 4LOXA 3E54A 5A0WA 2VS8A 1MOWA 5E67A 4UN8A 1LWSA 2XE0A 4UNCA 3HYIA 4D6OA 2VS7A 5E5OA 1AF5A 4UNBA 3QQYA 2VBOA 4UN7A 4AAGA 1LWTA 5A0MA 4UN9G 2I3QA 2VBLB 3KO2A 1T9IA 3FD2A 1G9YA 3HYJA 1T9JA 3C0XA 2DCHX 4AAEA 3MIPA 1BP7A 4AQXA 2CW7A 5AKNA 3MXBA 3MX9A 2XE0B 1R7MA 3MISA 1M5XA 5AKMA 1JVAA 1U0CA 4YITA 4AAFA 3R7PA 2VBOB 5A0MB 1N3FA 5A72A 4UNAA 1VDEA 5E5SA 5AK9A 2VBNA 1DQ3A
chains in the Genus database with same CATH superfamily
3EH8A 5AKFA 4AADA 4KZSA 4AABA 1B24A 4Z1XA 2I3PA 5A78A 3MXBB 3OORA 1G9ZA 2O7MA 2VBJA 1EF0A 4UN8G 4UN9A 3MXAA 2FLDA 2VBNB 4Z20A 5A77A 4UN7G 3C0WA 4EFJA 1U0DA 1P8KZ 4UT0A 2QOJZ 2CW8A 3UVFA 2VBJB 4D6NA 4Z1ZA 4YISA 1UM2A 2EX5A 5E63A 5A74A 1DFAA 2AB5A 3OOLA 4AQUA 4LQ0A 1N3EA 4YHXA 2VBLA 4LOXA 3E54A 5A0WA 2VS8A 1MOWA 5E67A 4UN8A 1LWSA 2XE0A 4UNCA 3HYIA 4D6OA 2VS7A 5E5OA 1AF5A 4UNBA 3QQYA 2VBOA 4UN7A 4AAGA 1LWTA 5A0MA 4UN9G 2I3QA 2VBLB 3KO2A 1T9IA 3FD2A 1G9YA 3HYJA 1T9JA 3C0XA 2DCHX 4AAEA 3MIPA 1BP7A 4AQXA 2CW7A 5AKNA 3MXBA 3MX9A 2XE0B 1R7MA 3MISA 1M5XA 5AKMA 1JVAA 1U0CA 4YITA 4AAFA 3R7PA 2F4LA 2VBOB 5A0MB 1N3FA 5A72A 4UNAA 1VDEA 5E5SA 5AK9A 2VBNA 1DQ3A
chains in the Genus database with same CATH topology
3EH8A 5AKFA 4AADA 4AABA 1B24A 4Z1XA 2I3PA 5A78A 3MXBB 3OORA 1G9ZA 2O7MA 2VBJA 1EF0A 4UN8G 4UN9A 3MXAA 2FLDA 2VBNB 4Z20A 5A77A 4UN7G 3C0WA 4EFJA 1U0DA 1P8KZ 4UT0A 2QOJZ 2CW8A 3UVFA 2VBJB 4D6NA 4Z1ZA 4YISA 1UM2A 2EX5A 5E63A 5A74A 1DFAA 2AB5A 3OOLA 4AQUA 4LQ0A 1N3EA 4YHXA 2VBLA 4LOXA 3E54A 5A0WA 2VS8A 1MOWA 5E67A 4UN8A 1LWSA 2XE0A 4UNCA 3HYIA 4D6OA 2VS7A 5E5OA 1AF5A 4UNBA 3QQYA 2VBOA 4UN7A 4AAGA 1LWTA 5A0MA 4UN9G 2I3QA 2VBLB 3KO2A 1T9IA 3FD2A 1G9YA 3HYJA 1T9JA 3C0XA 2DCHX 4AAEA 3MIPA 1BP7A 4AQXA 2CW7A 5AKNA 3MXBA 3MX9A 2XE0B 1R7MA 3MISA 1M5XA 5AKMA 1JVAA 1U0CA 4YITA 4AAFA 3R7PA 2VBOB 5A0MB 1N3FA 5A72A 4UNAA 1VDEA 5E5SA 5AK9A 2VBNA 1DQ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3EH8 A;  5AKF A;  4AAD A;  4AAB A;  1B24 A;  4Z1X A;  2I3P A;  5A78 A;  3MXB B;  3OOR A;  1G9Z A;  2O7M A;  2VBJ A;  1EF0 A;  4UN8 G;  4UN9 A;  3MXA A;  2FLD A;  2VBN B;  4Z20 A;  5A77 A;  4UN7 G;  3C0W A;  4EFJ A;  1U0D A;  1P8K Z;  4UT0 A;  2QOJ Z;  2CW8 A;  3UVF A;  2VBJ B;  4D6N A;  4Z1Z A;  4YIS A;  1UM2 A;  2EX5 A;  5E63 A;  5A74 A;  1DFA A;  2AB5 A;  3OOL A;  4AQU A;  4LQ0 A;  1N3E A;  4YHX A;  2VBL A;  4LOX A;  3E54 A;  5A0W A;  2VS8 A;  1MOW A;  5E67 A;  4UN8 A;  1LWS A;  2XE0 A;  4UNC A;  3HYI A;  4D6O A;  2VS7 A;  5E5O A;  1AF5 A;  4UNB A;  3QQY A;  2VBO A;  4UN7 A;  4AAG A;  1LWT A;  5A0M A;  4UN9 G;  2I3Q A;  2VBL B;  3KO2 A;  1T9I A;  3FD2 A;  1G9Y A;  3HYJ A;  1T9J A;  3C0X A;  2DCH X;  4AAE A;  3MIP A;  1BP7 A;  4AQX A;  2CW7 A;  5AKN A;  3MXB A;  3MX9 A;  2XE0 B;  1R7M A;  3MIS A;  1M5X A;  5AKM A;  1JVA A;  1U0C A;  4YIT A;  4AAF A;  3R7P A;  2VBO B;  5A0M B;  1N3F A;  5A72 A;  4UNA A;  1VDE A;  5E5S A;  5AK9 A;  2VBN A;  1DQ3 A; 
#chains in the Genus database with same CATH topology
 3EH8 A;  5AKF A;  4AAD A;  4KZS A;  4AAB A;  1B24 A;  4Z1X A;  2I3P A;  5A78 A;  3MXB B;  3OOR A;  1G9Z A;  2O7M A;  2VBJ A;  1EF0 A;  4UN8 G;  4UN9 A;  3MXA A;  2FLD A;  2VBN B;  4Z20 A;  5A77 A;  4UN7 G;  3C0W A;  4EFJ A;  1U0D A;  1P8K Z;  4UT0 A;  2QOJ Z;  2CW8 A;  3UVF A;  2VBJ B;  4D6N A;  4Z1Z A;  4YIS A;  1UM2 A;  2EX5 A;  5E63 A;  5A74 A;  1DFA A;  2AB5 A;  3OOL A;  4AQU A;  4LQ0 A;  1N3E A;  4YHX A;  2VBL A;  4LOX A;  3E54 A;  5A0W A;  2VS8 A;  1MOW A;  5E67 A;  4UN8 A;  1LWS A;  2XE0 A;  4UNC A;  3HYI A;  4D6O A;  2VS7 A;  5E5O A;  1AF5 A;  4UNB A;  3QQY A;  2VBO A;  4UN7 A;  4AAG A;  1LWT A;  5A0M A;  4UN9 G;  2I3Q A;  2VBL B;  3KO2 A;  1T9I A;  3FD2 A;  1G9Y A;  3HYJ A;  1T9J A;  3C0X A;  2DCH X;  4AAE A;  3MIP A;  1BP7 A;  4AQX A;  2CW7 A;  5AKN A;  3MXB A;  3MX9 A;  2XE0 B;  1R7M A;  3MIS A;  1M5X A;  5AKM A;  1JVA A;  1U0C A;  4YIT A;  4AAF A;  3R7P A;  2F4L A;  2VBO B;  5A0M B;  1N3F A;  5A72 A;  4UNA A;  1VDE A;  5E5S A;  5AK9 A;  2VBN A;  1DQ3 A; 
#chains in the Genus database with same CATH homology
 3EH8 A;  5AKF A;  4AAD A;  4AAB A;  1B24 A;  4Z1X A;  2I3P A;  5A78 A;  3MXB B;  3OOR A;  1G9Z A;  2O7M A;  2VBJ A;  1EF0 A;  4UN8 G;  4UN9 A;  3MXA A;  2FLD A;  2VBN B;  4Z20 A;  5A77 A;  4UN7 G;  3C0W A;  4EFJ A;  1U0D A;  1P8K Z;  4UT0 A;  2QOJ Z;  2CW8 A;  3UVF A;  2VBJ B;  4D6N A;  4Z1Z A;  4YIS A;  1UM2 A;  2EX5 A;  5E63 A;  5A74 A;  1DFA A;  2AB5 A;  3OOL A;  4AQU A;  4LQ0 A;  1N3E A;  4YHX A;  2VBL A;  4LOX A;  3E54 A;  5A0W A;  2VS8 A;  1MOW A;  5E67 A;  4UN8 A;  1LWS A;  2XE0 A;  4UNC A;  3HYI A;  4D6O A;  2VS7 A;  5E5O A;  1AF5 A;  4UNB A;  3QQY A;  2VBO A;  4UN7 A;  4AAG A;  1LWT A;  5A0M A;  4UN9 G;  2I3Q A;  2VBL B;  3KO2 A;  1T9I A;  3FD2 A;  1G9Y A;  3HYJ A;  1T9J A;  3C0X A;  2DCH X;  4AAE A;  3MIP A;  1BP7 A;  4AQX A;  2CW7 A;  5AKN A;  3MXB A;  3MX9 A;  2XE0 B;  1R7M A;  3MIS A;  1M5X A;  5AKM A;  1JVA A;  1U0C A;  4YIT A;  4AAF A;  3R7P A;  2VBO B;  5A0M B;  1N3F A;  5A72 A;  4UNA A;  1VDE A;  5E5S A;  5AK9 A;  2VBN A;  1DQ3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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