4Z20A

Crystal structure of meganuclease i-smami bound to uncleaveable dna with a ttgt central four
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
300
structure length
298
Chain Sequence
GENSKLNPWAVVGFIDAEGSFMVRVRKNSKYKTGWLVVAIFSVTVDKKDLFLLESLKTFFGGLGSIKKSGNSTFSYRIESSEQLTKIILPFFDKYSLITEKLGDYLLFKKVLELMGTKEHLTQRGLEKIVSLKASINKGLSEELQAAFPQCVPTPRPNNKNIPDPFWLAGFVSGDGSFKSILKKSESIKVGFQSILVFQITQHARDVKLMESLISYLGCGFIEKDSRGPWLYYTVTNFSDIQGKIIPFFHQYKIIGSKYGDYQDWCKIALIMQNKNHLTPEGLNEIRALKGGMNKGRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Sordaria macrospora (strain atcc mya-333 / dsm 997 / k(l3346) / k-hell)
molecule keywords MEGANUCLEASE I-SMAMI
total genus 84
structure length 298
sequence length 300
chains with identical sequence D
ec nomenclature
pdb deposition date 2015-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4z20A01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 4z20A02
4D6NA 5E5OA 2CW8A 3E54A 4AAFA 1MOWA 4UN9A 3MXBA 5AKFA 2VBNA 1LWTA 2O7MA 2XE0A 1G9ZA 4UN8A 3HYIA 2DCHX 5E63A 5AK9A 2VBJA 1DFAA 2CW7A 1U0CA 3QQYA 1U0DA 4AQXA 1N3FA 1R7MA 1EF0A 3R7PA 1P8KZ 4YISA 1T9JA 2I3PA 3OOLA 5AKNA 1B24A 5E5SA 2VBOB 4AAEA 4AADA 1T9IA 2AB5A 1BP7A 4LQ0A 5A0MB 4LOXA 3MX9A 1JVAA 1LWSA 4UNBA 3MISA 2VBLB 3KO2A 4EFJA 2EX5A 2VS8A 4Z20A 3OORA 4AABA 3MXBB 4UNCA 2VBNB 5A78A 5A72A 4Z1XA 2XE0B 2VBJB 2QOJZ 4YHXA 3HYJA 4AAGA 5A74A 5A77A 4AQUA 2VS7A 4YITA 4UN7G 1VDEA 4UNAA 3MIPA 4D6OA 3UVFA 1AF5A 1N3EA 1UM2A 3FD2A 4UN9G 2FLDA 1G9YA 2I3QA 3EH8A 3C0XA 4UN8G 5AKMA 1DQ3A 5A0WA 2VBOA 1M5XA 5E67A 4UT0A 5A0MA 4Z1ZA 2VBLA 3C0WA 4UN7A 3MXAA
chains in the Genus database with same CATH superfamily
4D6NA 5E5OA 2CW8A 3E54A 4AAFA 1MOWA 4UN9A 2F4LA 3MXBA 5AKFA 2VBNA 1LWTA 2O7MA 2XE0A 1G9ZA 4UN8A 3HYIA 2DCHX 5E63A 5AK9A 2VBJA 1DFAA 2CW7A 1U0CA 3QQYA 1U0DA 4AQXA 1N3FA 1R7MA 1EF0A 3R7PA 1P8KZ 4YISA 1T9JA 2I3PA 3OOLA 5AKNA 1B24A 5E5SA 2VBOB 4AAEA 4AADA 1T9IA 2AB5A 1BP7A 4LQ0A 5A0MB 4LOXA 3MX9A 1JVAA 1LWSA 4UNBA 3MISA 2VBLB 3KO2A 4EFJA 2EX5A 2VS8A 4Z20A 3OORA 4AABA 3MXBB 4UNCA 2VBNB 5A78A 5A72A 4Z1XA 2XE0B 2VBJB 2QOJZ 4YHXA 3HYJA 4AAGA 5A74A 5A77A 4AQUA 2VS7A 4YITA 4UN7G 1VDEA 4UNAA 4KZSA 3MIPA 4D6OA 3UVFA 1AF5A 1N3EA 1UM2A 3FD2A 4UN9G 2FLDA 1G9YA 2I3QA 3EH8A 3C0XA 4UN8G 5AKMA 1DQ3A 5A0WA 2VBOA 1M5XA 5E67A 4UT0A 5A0MA 4Z1ZA 2VBLA 3C0WA 4UN7A 3MXAA
chains in the Genus database with same CATH topology
4D6NA 5E5OA 2CW8A 3E54A 4AAFA 1MOWA 4UN9A 3MXBA 5AKFA 2VBNA 1LWTA 2O7MA 2XE0A 1G9ZA 4UN8A 3HYIA 2DCHX 5E63A 5AK9A 2VBJA 1DFAA 2CW7A 1U0CA 3QQYA 1U0DA 4AQXA 1N3FA 1R7MA 1EF0A 3R7PA 1P8KZ 4YISA 1T9JA 2I3PA 3OOLA 5AKNA 1B24A 5E5SA 2VBOB 4AAEA 4AADA 1T9IA 2AB5A 1BP7A 4LQ0A 5A0MB 4LOXA 3MX9A 1JVAA 1LWSA 4UNBA 3MISA 2VBLB 3KO2A 4EFJA 2EX5A 2VS8A 4Z20A 3OORA 4AABA 3MXBB 4UNCA 2VBNB 5A78A 5A72A 4Z1XA 2XE0B 2VBJB 2QOJZ 4YHXA 3HYJA 4AAGA 5A74A 5A77A 4AQUA 2VS7A 4YITA 4UN7G 1VDEA 4UNAA 3MIPA 4D6OA 3UVFA 1AF5A 1N3EA 1UM2A 3FD2A 4UN9G 2FLDA 1G9YA 2I3QA 3EH8A 3C0XA 4UN8G 5AKMA 1DQ3A 5A0WA 2VBOA 1M5XA 5E67A 4UT0A 5A0MA 4Z1ZA 2VBLA 3C0WA 4UN7A 3MXAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D6N A;  5E5O A;  2CW8 A;  3E54 A;  4AAF A;  1MOW A;  4UN9 A;  3MXB A;  5AKF A;  2VBN A;  1LWT A;  2O7M A;  2XE0 A;  1G9Z A;  4UN8 A;  3HYI A;  2DCH X;  5E63 A;  5AK9 A;  2VBJ A;  1DFA A;  2CW7 A;  1U0C A;  3QQY A;  1U0D A;  4AQX A;  1N3F A;  1R7M A;  1EF0 A;  3R7P A;  1P8K Z;  4YIS A;  1T9J A;  2I3P A;  3OOL A;  5AKN A;  1B24 A;  5E5S A;  2VBO B;  4AAE A;  4AAD A;  1T9I A;  2AB5 A;  1BP7 A;  4LQ0 A;  5A0M B;  4LOX A;  3MX9 A;  1JVA A;  1LWS A;  4UNB A;  3MIS A;  2VBL B;  3KO2 A;  4EFJ A;  2EX5 A;  2VS8 A;  4Z20 A;  3OOR A;  4AAB A;  3MXB B;  4UNC A;  2VBN B;  5A78 A;  5A72 A;  4Z1X A;  2XE0 B;  2VBJ B;  2QOJ Z;  4YHX A;  3HYJ A;  4AAG A;  5A74 A;  5A77 A;  4AQU A;  2VS7 A;  4YIT A;  4UN7 G;  1VDE A;  4UNA A;  3MIP A;  4D6O A;  3UVF A;  1AF5 A;  1N3E A;  1UM2 A;  3FD2 A;  4UN9 G;  2FLD A;  1G9Y A;  2I3Q A;  3EH8 A;  3C0X A;  4UN8 G;  5AKM A;  1DQ3 A;  5A0W A;  2VBO A;  1M5X A;  5E67 A;  4UT0 A;  5A0M A;  4Z1Z A;  2VBL A;  3C0W A;  4UN7 A;  3MXA A; 
#chains in the Genus database with same CATH topology
 4D6N A;  5E5O A;  2CW8 A;  3E54 A;  4AAF A;  1MOW A;  4UN9 A;  2F4L A;  3MXB A;  5AKF A;  2VBN A;  1LWT A;  2O7M A;  2XE0 A;  1G9Z A;  4UN8 A;  3HYI A;  2DCH X;  5E63 A;  5AK9 A;  2VBJ A;  1DFA A;  2CW7 A;  1U0C A;  3QQY A;  1U0D A;  4AQX A;  1N3F A;  1R7M A;  1EF0 A;  3R7P A;  1P8K Z;  4YIS A;  1T9J A;  2I3P A;  3OOL A;  5AKN A;  1B24 A;  5E5S A;  2VBO B;  4AAE A;  4AAD A;  1T9I A;  2AB5 A;  1BP7 A;  4LQ0 A;  5A0M B;  4LOX A;  3MX9 A;  1JVA A;  1LWS A;  4UNB A;  3MIS A;  2VBL B;  3KO2 A;  4EFJ A;  2EX5 A;  2VS8 A;  4Z20 A;  3OOR A;  4AAB A;  3MXB B;  4UNC A;  2VBN B;  5A78 A;  5A72 A;  4Z1X A;  2XE0 B;  2VBJ B;  2QOJ Z;  4YHX A;  3HYJ A;  4AAG A;  5A74 A;  5A77 A;  4AQU A;  2VS7 A;  4YIT A;  4UN7 G;  1VDE A;  4UNA A;  4KZS A;  3MIP A;  4D6O A;  3UVF A;  1AF5 A;  1N3E A;  1UM2 A;  3FD2 A;  4UN9 G;  2FLD A;  1G9Y A;  2I3Q A;  3EH8 A;  3C0X A;  4UN8 G;  5AKM A;  1DQ3 A;  5A0W A;  2VBO A;  1M5X A;  5E67 A;  4UT0 A;  5A0M A;  4Z1Z A;  2VBL A;  3C0W A;  4UN7 A;  3MXA A; 
#chains in the Genus database with same CATH homology
 4D6N A;  5E5O A;  2CW8 A;  3E54 A;  4AAF A;  1MOW A;  4UN9 A;  3MXB A;  5AKF A;  2VBN A;  1LWT A;  2O7M A;  2XE0 A;  1G9Z A;  4UN8 A;  3HYI A;  2DCH X;  5E63 A;  5AK9 A;  2VBJ A;  1DFA A;  2CW7 A;  1U0C A;  3QQY A;  1U0D A;  4AQX A;  1N3F A;  1R7M A;  1EF0 A;  3R7P A;  1P8K Z;  4YIS A;  1T9J A;  2I3P A;  3OOL A;  5AKN A;  1B24 A;  5E5S A;  2VBO B;  4AAE A;  4AAD A;  1T9I A;  2AB5 A;  1BP7 A;  4LQ0 A;  5A0M B;  4LOX A;  3MX9 A;  1JVA A;  1LWS A;  4UNB A;  3MIS A;  2VBL B;  3KO2 A;  4EFJ A;  2EX5 A;  2VS8 A;  4Z20 A;  3OOR A;  4AAB A;  3MXB B;  4UNC A;  2VBN B;  5A78 A;  5A72 A;  4Z1X A;  2XE0 B;  2VBJ B;  2QOJ Z;  4YHX A;  3HYJ A;  4AAG A;  5A74 A;  5A77 A;  4AQU A;  2VS7 A;  4YIT A;  4UN7 G;  1VDE A;  4UNA A;  3MIP A;  4D6O A;  3UVF A;  1AF5 A;  1N3E A;  1UM2 A;  3FD2 A;  4UN9 G;  2FLD A;  1G9Y A;  2I3Q A;  3EH8 A;  3C0X A;  4UN8 G;  5AKM A;  1DQ3 A;  5A0W A;  2VBO A;  1M5X A;  5E67 A;  4UT0 A;  5A0M A;  4Z1Z A;  2VBL A;  3C0W A;  4UN7 A;  3MXA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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