5A0MA

The crystal structure of i-scei in complex with its target dna in the presence of mn
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
224
structure length
224
Chain Sequence
NIKKNQVMNLGPNSKLLKEYKSQLIELNIEQFEAGIGLILGDAYIRSRDEGKTYCMQFEWKNKAYMDHVCLLYDQWVLSPPHKKERVNHLGNLVITWGAQTFKHQAFNKLANLFIVNNKKTIPNNLVENYLTPMSLAYWFMDDGGKWDYNKNSTNKSIVLNTQSFTFEEVEYLVKGLRNKFQLNCYVKINKNKPIIYIDSMSYLIFYNLIKPYLIPQMMYKLPN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the I-Scei Nuclease Complexed with its DsDNA Target and Three Catalytic Metal Ions.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
molecule keywords INTRON-ENCODED ENDONUCLEASE I-SCEI
total genus 64
structure length 224
sequence length 224
ec nomenclature ec 3.1.-.-:
pdb deposition date 2015-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03161 LAGLIDADG_2 LAGLIDADG DNA endonuclease family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5a0mA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5a0mA02
5AK9A 4UNCA 3MXBB 4AADA 5A78A 3UVFA 4UT0A 3C0XA 3HYJA 4D6OA 5E63A 3R7PA 1UM2A 3KO2A 4Z1ZA 1DFAA 2VBOB 3EH8A 4AABA 2DCHX 2VBLA 4AQUA 1T9IA 1N3FA 4UN7G 2VS8A 3MISA 5E5SA 2QOJZ 4Z20A 1BP7A 4AQXA 4LOXA 1VDEA 4YITA 3QQYA 4YISA 2I3PA 3MXAA 1JVAA 4AAFA 4UN7A 5E5OA 4UN9G 4AAEA 1N3EA 4AAGA 2VBNA 2VBJA 2VBLB 2FLDA 5AKNA 5A0MA 5AKMA 1T9JA 1M5XA 2XE0A 2I3QA 1DQ3A 2O7MA 3HYIA 1P8KZ 2VBNB 5A0WA 4UNBA 1R7MA 3E54A 5A72A 1MOWA 1LWTA 2CW8A 4UN8G 3MIPA 3MXBA 4UN9A 5E67A 4D6NA 4Z1XA 4YHXA 5A0MB 5AKFA 2VS7A 2XE0B 5A77A 3C0WA 2VBOA 1B24A 4UN8A 4LQ0A 1U0CA 2CW7A 1G9ZA 3OOLA 3OORA 1U0DA 5A74A 1AF5A 3FD2A 1EF0A 2EX5A 2AB5A 4EFJA 2VBJB 1G9YA 4UNAA 3MX9A 1LWSA
chains in the Genus database with same CATH superfamily
5AK9A 4UNCA 3MXBB 4AADA 4KZSA 5A78A 3UVFA 4UT0A 3C0XA 3HYJA 4D6OA 5E63A 3R7PA 2F4LA 1UM2A 3KO2A 4Z1ZA 1DFAA 2VBOB 3EH8A 4AABA 2DCHX 2VBLA 4AQUA 1T9IA 1N3FA 4UN7G 2VS8A 3MISA 5E5SA 2QOJZ 4Z20A 1BP7A 4AQXA 4LOXA 1VDEA 4YITA 3QQYA 4YISA 2I3PA 3MXAA 1JVAA 4AAFA 4UN7A 5E5OA 4UN9G 4AAEA 1N3EA 4AAGA 2VBNA 2VBJA 2VBLB 2FLDA 5AKNA 5A0MA 5AKMA 1T9JA 1M5XA 2XE0A 2I3QA 1DQ3A 2O7MA 3HYIA 1P8KZ 2VBNB 5A0WA 4UNBA 1R7MA 3E54A 5A72A 1MOWA 1LWTA 2CW8A 4UN8G 3MIPA 3MXBA 4UN9A 5E67A 4D6NA 4Z1XA 4YHXA 5A0MB 5AKFA 2VS7A 2XE0B 5A77A 3C0WA 2VBOA 1B24A 4UN8A 4LQ0A 1U0CA 2CW7A 1G9ZA 3OOLA 3OORA 1U0DA 5A74A 1AF5A 3FD2A 1EF0A 2EX5A 2AB5A 4EFJA 2VBJB 1G9YA 4UNAA 3MX9A 1LWSA
chains in the Genus database with same CATH topology
5AK9A 4UNCA 3MXBB 4AADA 5A78A 3UVFA 4UT0A 3C0XA 3HYJA 4D6OA 5E63A 3R7PA 1UM2A 3KO2A 4Z1ZA 1DFAA 2VBOB 3EH8A 4AABA 2DCHX 2VBLA 4AQUA 1T9IA 1N3FA 4UN7G 2VS8A 3MISA 5E5SA 2QOJZ 4Z20A 1BP7A 4AQXA 4LOXA 1VDEA 4YITA 3QQYA 4YISA 2I3PA 3MXAA 1JVAA 4AAFA 4UN7A 5E5OA 4UN9G 4AAEA 1N3EA 4AAGA 2VBNA 2VBJA 2VBLB 2FLDA 5AKNA 5A0MA 5AKMA 1T9JA 1M5XA 2XE0A 2I3QA 1DQ3A 2O7MA 3HYIA 1P8KZ 2VBNB 5A0WA 4UNBA 1R7MA 3E54A 5A72A 1MOWA 1LWTA 2CW8A 4UN8G 3MIPA 3MXBA 4UN9A 5E67A 4D6NA 4Z1XA 4YHXA 5A0MB 5AKFA 2VS7A 2XE0B 5A77A 3C0WA 2VBOA 1B24A 4UN8A 4LQ0A 1U0CA 2CW7A 1G9ZA 3OOLA 3OORA 1U0DA 5A74A 1AF5A 3FD2A 1EF0A 2EX5A 2AB5A 4EFJA 2VBJB 1G9YA 4UNAA 3MX9A 1LWSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5AK9 A;  4UNC A;  3MXB B;  4AAD A;  5A78 A;  3UVF A;  4UT0 A;  3C0X A;  3HYJ A;  4D6O A;  5E63 A;  3R7P A;  1UM2 A;  3KO2 A;  4Z1Z A;  1DFA A;  2VBO B;  3EH8 A;  4AAB A;  2DCH X;  2VBL A;  4AQU A;  1T9I A;  1N3F A;  4UN7 G;  2VS8 A;  3MIS A;  5E5S A;  2QOJ Z;  4Z20 A;  1BP7 A;  4AQX A;  4LOX A;  1VDE A;  4YIT A;  3QQY A;  4YIS A;  2I3P A;  3MXA A;  1JVA A;  4AAF A;  4UN7 A;  5E5O A;  4UN9 G;  4AAE A;  1N3E A;  4AAG A;  2VBN A;  2VBJ A;  2VBL B;  2FLD A;  5AKN A;  5A0M A;  5AKM A;  1T9J A;  1M5X A;  2XE0 A;  2I3Q A;  1DQ3 A;  2O7M A;  3HYI A;  1P8K Z;  2VBN B;  5A0W A;  4UNB A;  1R7M A;  3E54 A;  5A72 A;  1MOW A;  1LWT A;  2CW8 A;  4UN8 G;  3MIP A;  3MXB A;  4UN9 A;  5E67 A;  4D6N A;  4Z1X A;  4YHX A;  5A0M B;  5AKF A;  2VS7 A;  2XE0 B;  5A77 A;  3C0W A;  2VBO A;  1B24 A;  4UN8 A;  4LQ0 A;  1U0C A;  2CW7 A;  1G9Z A;  3OOL A;  3OOR A;  1U0D A;  5A74 A;  1AF5 A;  3FD2 A;  1EF0 A;  2EX5 A;  2AB5 A;  4EFJ A;  2VBJ B;  1G9Y A;  4UNA A;  3MX9 A;  1LWS A; 
#chains in the Genus database with same CATH topology
 5AK9 A;  4UNC A;  3MXB B;  4AAD A;  4KZS A;  5A78 A;  3UVF A;  4UT0 A;  3C0X A;  3HYJ A;  4D6O A;  5E63 A;  3R7P A;  2F4L A;  1UM2 A;  3KO2 A;  4Z1Z A;  1DFA A;  2VBO B;  3EH8 A;  4AAB A;  2DCH X;  2VBL A;  4AQU A;  1T9I A;  1N3F A;  4UN7 G;  2VS8 A;  3MIS A;  5E5S A;  2QOJ Z;  4Z20 A;  1BP7 A;  4AQX A;  4LOX A;  1VDE A;  4YIT A;  3QQY A;  4YIS A;  2I3P A;  3MXA A;  1JVA A;  4AAF A;  4UN7 A;  5E5O A;  4UN9 G;  4AAE A;  1N3E A;  4AAG A;  2VBN A;  2VBJ A;  2VBL B;  2FLD A;  5AKN A;  5A0M A;  5AKM A;  1T9J A;  1M5X A;  2XE0 A;  2I3Q A;  1DQ3 A;  2O7M A;  3HYI A;  1P8K Z;  2VBN B;  5A0W A;  4UNB A;  1R7M A;  3E54 A;  5A72 A;  1MOW A;  1LWT A;  2CW8 A;  4UN8 G;  3MIP A;  3MXB A;  4UN9 A;  5E67 A;  4D6N A;  4Z1X A;  4YHX A;  5A0M B;  5AKF A;  2VS7 A;  2XE0 B;  5A77 A;  3C0W A;  2VBO A;  1B24 A;  4UN8 A;  4LQ0 A;  1U0C A;  2CW7 A;  1G9Z A;  3OOL A;  3OOR A;  1U0D A;  5A74 A;  1AF5 A;  3FD2 A;  1EF0 A;  2EX5 A;  2AB5 A;  4EFJ A;  2VBJ B;  1G9Y A;  4UNA A;  3MX9 A;  1LWS A; 
#chains in the Genus database with same CATH homology
 5AK9 A;  4UNC A;  3MXB B;  4AAD A;  5A78 A;  3UVF A;  4UT0 A;  3C0X A;  3HYJ A;  4D6O A;  5E63 A;  3R7P A;  1UM2 A;  3KO2 A;  4Z1Z A;  1DFA A;  2VBO B;  3EH8 A;  4AAB A;  2DCH X;  2VBL A;  4AQU A;  1T9I A;  1N3F A;  4UN7 G;  2VS8 A;  3MIS A;  5E5S A;  2QOJ Z;  4Z20 A;  1BP7 A;  4AQX A;  4LOX A;  1VDE A;  4YIT A;  3QQY A;  4YIS A;  2I3P A;  3MXA A;  1JVA A;  4AAF A;  4UN7 A;  5E5O A;  4UN9 G;  4AAE A;  1N3E A;  4AAG A;  2VBN A;  2VBJ A;  2VBL B;  2FLD A;  5AKN A;  5A0M A;  5AKM A;  1T9J A;  1M5X A;  2XE0 A;  2I3Q A;  1DQ3 A;  2O7M A;  3HYI A;  1P8K Z;  2VBN B;  5A0W A;  4UNB A;  1R7M A;  3E54 A;  5A72 A;  1MOW A;  1LWT A;  2CW8 A;  4UN8 G;  3MIP A;  3MXB A;  4UN9 A;  5E67 A;  4D6N A;  4Z1X A;  4YHX A;  5A0M B;  5AKF A;  2VS7 A;  2XE0 B;  5A77 A;  3C0W A;  2VBO A;  1B24 A;  4UN8 A;  4LQ0 A;  1U0C A;  2CW7 A;  1G9Z A;  3OOL A;  3OOR A;  1U0D A;  5A74 A;  1AF5 A;  3FD2 A;  1EF0 A;  2EX5 A;  2AB5 A;  4EFJ A;  2VBJ B;  1G9Y A;  4UNA A;  3MX9 A;  1LWS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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