5A0MB

The crystal structure of i-scei in complex with its target dna in the presence of mn
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
227
structure length
227
Chain Sequence
KNIKKNQVMNLGPNSKLLKEYKSQLIELNIEQFEAGIGLILGDAYIRSRDEGKTYCMQFEWKNKAYMDHVCLLYDQWVLSPPHKKERVNHLGNLVITWGAQTFKHQAFNKLANLFIVNNKKTIPNNLVENYLTPMSLAYWFMDDGGKWDYNKNSTNTSIVLNTQSFTFEEVEYLVKGLRNKFQLNCYVKINKNKPIIYIDSMSYLIFYNLIKPYLIPQMMYKLPNTI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the I-Scei Nuclease Complexed with its DsDNA Target and Three Catalytic Metal Ions.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Saccharomyces cerevisiae
molecule keywords INTRON-ENCODED ENDONUCLEASE I-SCEI
total genus 57
structure length 227
sequence length 227
ec nomenclature ec 3.1.-.-:
pdb deposition date 2015-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03161 LAGLIDADG_2 LAGLIDADG DNA endonuclease family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5a0mB01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5a0mB02
4UN7A 1B24A 3MXBA 3OOLA 3OORA 2O7MA 4D6NA 1P8KZ 5AKMA 1VDEA 4AQUA 2CW7A 4YITA 5A77A 3E54A 4UN7G 3MXBB 1N3EA 4AAEA 4AAFA 5AKNA 5A74A 3MIPA 1DQ3A 3FD2A 1LWTA 1MOWA 2CW8A 5A0MA 4AABA 3HYJA 4EFJA 2I3PA 4UN8A 4LOXA 2VBLA 2AB5A 4Z20A 4LQ0A 3MX9A 4UN9A 3MISA 1T9JA 1EF0A 2VBLB 2DCHX 4UN8G 2VBOA 3HYIA 1JVAA 2VBOB 4AADA 1T9IA 2I3QA 2VS7A 5E5OA 1AF5A 2EX5A 4D6OA 1LWSA 4Z1ZA 5E67A 5AK9A 2VBNA 1DFAA 4UNCA 5AKFA 1G9ZA 4UN9G 2VBNB 4UT0A 5A72A 3MXAA 1R7MA 5E5SA 1UM2A 2QOJZ 3EH8A 4Z1XA 4AQXA 5E63A 1G9YA 5A0WA 1M5XA 4UNBA 3KO2A 3UVFA 3R7PA 1U0DA 2XE0A 2FLDA 3C0XA 1BP7A 2VS8A 1N3FA 2XE0B 4YHXA 2VBJA 3C0WA 2VBJB 5A78A 4AAGA 4YISA 4UNAA 3QQYA 5A0MB 1U0CA
chains in the Genus database with same CATH superfamily
4UN7A 1B24A 3MXBA 3OOLA 3OORA 2O7MA 4D6NA 1P8KZ 5AKMA 1VDEA 4AQUA 2CW7A 4YITA 5A77A 3E54A 4UN7G 3MXBB 1N3EA 4AAEA 4AAFA 5AKNA 5A74A 3MIPA 1DQ3A 3FD2A 1LWTA 1MOWA 2CW8A 5A0MA 4AABA 3HYJA 4EFJA 2I3PA 4UN8A 4LOXA 2VBLA 2AB5A 4Z20A 4LQ0A 3MX9A 4UN9A 3MISA 1T9JA 1EF0A 2VBLB 2DCHX 4UN8G 2VBOA 3HYIA 1JVAA 2VBOB 4AADA 1T9IA 2I3QA 2VS7A 5E5OA 1AF5A 2F4LA 2EX5A 4D6OA 1LWSA 4Z1ZA 5E67A 5AK9A 2VBNA 1DFAA 4UNCA 5AKFA 1G9ZA 4UN9G 2VBNB 4UT0A 5A72A 3MXAA 1R7MA 5E5SA 1UM2A 2QOJZ 3EH8A 4Z1XA 4AQXA 5E63A 1G9YA 5A0WA 1M5XA 4UNBA 3KO2A 3UVFA 3R7PA 1U0DA 2XE0A 2FLDA 3C0XA 1BP7A 2VS8A 1N3FA 2XE0B 4YHXA 2VBJA 3C0WA 2VBJB 5A78A 4KZSA 4AAGA 4YISA 4UNAA 3QQYA 5A0MB 1U0CA
chains in the Genus database with same CATH topology
4UN7A 1B24A 3MXBA 3OOLA 3OORA 2O7MA 4D6NA 1P8KZ 5AKMA 1VDEA 4AQUA 2CW7A 4YITA 5A77A 3E54A 4UN7G 3MXBB 1N3EA 4AAEA 4AAFA 5AKNA 5A74A 3MIPA 1DQ3A 3FD2A 1LWTA 1MOWA 2CW8A 5A0MA 4AABA 3HYJA 4EFJA 2I3PA 4UN8A 4LOXA 2VBLA 2AB5A 4Z20A 4LQ0A 3MX9A 4UN9A 3MISA 1T9JA 1EF0A 2VBLB 2DCHX 4UN8G 2VBOA 3HYIA 1JVAA 2VBOB 4AADA 1T9IA 2I3QA 2VS7A 5E5OA 1AF5A 2EX5A 4D6OA 1LWSA 4Z1ZA 5E67A 5AK9A 2VBNA 1DFAA 4UNCA 5AKFA 1G9ZA 4UN9G 2VBNB 4UT0A 5A72A 3MXAA 1R7MA 5E5SA 1UM2A 2QOJZ 3EH8A 4Z1XA 4AQXA 5E63A 1G9YA 5A0WA 1M5XA 4UNBA 3KO2A 3UVFA 3R7PA 1U0DA 2XE0A 2FLDA 3C0XA 1BP7A 2VS8A 1N3FA 2XE0B 4YHXA 2VBJA 3C0WA 2VBJB 5A78A 4AAGA 4YISA 4UNAA 3QQYA 5A0MB 1U0CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4UN7 A;  1B24 A;  3MXB A;  3OOL A;  3OOR A;  2O7M A;  4D6N A;  1P8K Z;  5AKM A;  1VDE A;  4AQU A;  2CW7 A;  4YIT A;  5A77 A;  3E54 A;  4UN7 G;  3MXB B;  1N3E A;  4AAE A;  4AAF A;  5AKN A;  5A74 A;  3MIP A;  1DQ3 A;  3FD2 A;  1LWT A;  1MOW A;  2CW8 A;  5A0M A;  4AAB A;  3HYJ A;  4EFJ A;  2I3P A;  4UN8 A;  4LOX A;  2VBL A;  2AB5 A;  4Z20 A;  4LQ0 A;  3MX9 A;  4UN9 A;  3MIS A;  1T9J A;  1EF0 A;  2VBL B;  2DCH X;  4UN8 G;  2VBO A;  3HYI A;  1JVA A;  2VBO B;  4AAD A;  1T9I A;  2I3Q A;  2VS7 A;  5E5O A;  1AF5 A;  2EX5 A;  4D6O A;  1LWS A;  4Z1Z A;  5E67 A;  5AK9 A;  2VBN A;  1DFA A;  4UNC A;  5AKF A;  1G9Z A;  4UN9 G;  2VBN B;  4UT0 A;  5A72 A;  3MXA A;  1R7M A;  5E5S A;  1UM2 A;  2QOJ Z;  3EH8 A;  4Z1X A;  4AQX A;  5E63 A;  1G9Y A;  5A0W A;  1M5X A;  4UNB A;  3KO2 A;  3UVF A;  3R7P A;  1U0D A;  2XE0 A;  2FLD A;  3C0X A;  1BP7 A;  2VS8 A;  1N3F A;  2XE0 B;  4YHX A;  2VBJ A;  3C0W A;  2VBJ B;  5A78 A;  4AAG A;  4YIS A;  4UNA A;  3QQY A;  5A0M B;  1U0C A; 
#chains in the Genus database with same CATH topology
 4UN7 A;  1B24 A;  3MXB A;  3OOL A;  3OOR A;  2O7M A;  4D6N A;  1P8K Z;  5AKM A;  1VDE A;  4AQU A;  2CW7 A;  4YIT A;  5A77 A;  3E54 A;  4UN7 G;  3MXB B;  1N3E A;  4AAE A;  4AAF A;  5AKN A;  5A74 A;  3MIP A;  1DQ3 A;  3FD2 A;  1LWT A;  1MOW A;  2CW8 A;  5A0M A;  4AAB A;  3HYJ A;  4EFJ A;  2I3P A;  4UN8 A;  4LOX A;  2VBL A;  2AB5 A;  4Z20 A;  4LQ0 A;  3MX9 A;  4UN9 A;  3MIS A;  1T9J A;  1EF0 A;  2VBL B;  2DCH X;  4UN8 G;  2VBO A;  3HYI A;  1JVA A;  2VBO B;  4AAD A;  1T9I A;  2I3Q A;  2VS7 A;  5E5O A;  1AF5 A;  2F4L A;  2EX5 A;  4D6O A;  1LWS A;  4Z1Z A;  5E67 A;  5AK9 A;  2VBN A;  1DFA A;  4UNC A;  5AKF A;  1G9Z A;  4UN9 G;  2VBN B;  4UT0 A;  5A72 A;  3MXA A;  1R7M A;  5E5S A;  1UM2 A;  2QOJ Z;  3EH8 A;  4Z1X A;  4AQX A;  5E63 A;  1G9Y A;  5A0W A;  1M5X A;  4UNB A;  3KO2 A;  3UVF A;  3R7P A;  1U0D A;  2XE0 A;  2FLD A;  3C0X A;  1BP7 A;  2VS8 A;  1N3F A;  2XE0 B;  4YHX A;  2VBJ A;  3C0W A;  2VBJ B;  5A78 A;  4KZS A;  4AAG A;  4YIS A;  4UNA A;  3QQY A;  5A0M B;  1U0C A; 
#chains in the Genus database with same CATH homology
 4UN7 A;  1B24 A;  3MXB A;  3OOL A;  3OOR A;  2O7M A;  4D6N A;  1P8K Z;  5AKM A;  1VDE A;  4AQU A;  2CW7 A;  4YIT A;  5A77 A;  3E54 A;  4UN7 G;  3MXB B;  1N3E A;  4AAE A;  4AAF A;  5AKN A;  5A74 A;  3MIP A;  1DQ3 A;  3FD2 A;  1LWT A;  1MOW A;  2CW8 A;  5A0M A;  4AAB A;  3HYJ A;  4EFJ A;  2I3P A;  4UN8 A;  4LOX A;  2VBL A;  2AB5 A;  4Z20 A;  4LQ0 A;  3MX9 A;  4UN9 A;  3MIS A;  1T9J A;  1EF0 A;  2VBL B;  2DCH X;  4UN8 G;  2VBO A;  3HYI A;  1JVA A;  2VBO B;  4AAD A;  1T9I A;  2I3Q A;  2VS7 A;  5E5O A;  1AF5 A;  2EX5 A;  4D6O A;  1LWS A;  4Z1Z A;  5E67 A;  5AK9 A;  2VBN A;  1DFA A;  4UNC A;  5AKF A;  1G9Z A;  4UN9 G;  2VBN B;  4UT0 A;  5A72 A;  3MXA A;  1R7M A;  5E5S A;  1UM2 A;  2QOJ Z;  3EH8 A;  4Z1X A;  4AQX A;  5E63 A;  1G9Y A;  5A0W A;  1M5X A;  4UNB A;  3KO2 A;  3UVF A;  3R7P A;  1U0D A;  2XE0 A;  2FLD A;  3C0X A;  1BP7 A;  2VS8 A;  1N3F A;  2XE0 B;  4YHX A;  2VBJ A;  3C0W A;  2VBJ B;  5A78 A;  4AAG A;  4YIS A;  4UNA A;  3QQY A;  5A0M B;  1U0C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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