5A77A

Crystal structure of the homing endonuclease i-cvui in complex with i- crei target (c1221) in the presence of 2 mm mg revealing dna cleaved
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
157
structure length
157
Chain Sequence
NFHDQLKFAWLAGFVDADGCINAQIVSREDYLLKYQVRVSLTVFQSTTQHFILLDIQKILGCGTVRKRNDGMSEFCVVGGTSLQTTLEKLLPYLQLKRAQAKLVLQIIKKLPNTKDPSVLMEAALLADKVGLLTDGKKRTILAENVRECLKKLGHVV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Homing Endonuclease I-Cvui Provides a New Template for Genome Modification
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Chlorella vulgaris
molecule keywords DNA ENDONUCLEASE I-CVUI
total genus 49
structure length 157
sequence length 157
chains with identical sequence B
ec nomenclature ec 3.1.-.-:
pdb deposition date 2015-07-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5a77A00
2VS8A 3EH8A 2VBLB 4Z20A 1N3EA 1P8KZ 2XE0B 2VS7A 3KO2A 2VBJB 3HYJA 4UNAA 4UN8G 4EFJA 4Z1ZA 4UN7A 5AKMA 5A78A 1U0DA 4YISA 4AQXA 2AB5A 1DQ3A 5A0MB 1B24A 5AKNA 1EF0A 4LQ0A 1T9JA 5A77A 3MIPA 3MISA 1UM2A 3C0XA 2VBNB 3QQYA 2O7MA 2EX5A 3MXAA 4AABA 1G9ZA 2VBOB 1JVAA 5A0WA 2DCHX 4D6NA 4UT0A 1M5XA 1R7MA 4AAGA 2I3PA 1LWSA 3UVFA 3MXBA 1T9IA 4UN9A 3OOLA 3OORA 3MX9A 5E67A 3C0WA 4AAFA 1BP7A 5AKFA 3FD2A 5AK9A 4UN8A 2QOJZ 4UN7G 4AADA 5E5OA 2FLDA 1U0CA 1LWTA 2XE0A 4UNBA 1G9YA 5A74A 3E54A 3HYIA 5E63A 4YHXA 4Z1XA 5A0MA 1VDEA 3MXBB 2CW7A 4D6OA 3R7PA 5A72A 2I3QA 4AAEA 4AQUA 2VBNA 2VBLA 2CW8A 1N3FA 1AF5A 1MOWA 4YITA 1DFAA 4LOXA 2VBOA 2VBJA 4UNCA 4UN9G 5E5SA
chains in the Genus database with same CATH superfamily
2VS8A 3EH8A 2VBLB 4Z20A 1N3EA 1P8KZ 2XE0B 2VS7A 3KO2A 2VBJB 3HYJA 4UNAA 4UN8G 4EFJA 4Z1ZA 4UN7A 5AKMA 5A78A 1U0DA 4YISA 4AQXA 2AB5A 1DQ3A 1B24A 5A0MB 5AKNA 1EF0A 4KZSA 4LQ0A 1T9JA 5A77A 3MIPA 3MISA 1UM2A 3C0XA 2VBNB 3QQYA 2O7MA 2EX5A 3MXAA 4AABA 1G9ZA 2VBOB 1JVAA 5A0WA 2DCHX 4D6NA 4UT0A 1M5XA 1R7MA 4AAGA 2I3PA 1LWSA 3UVFA 3MXBA 1T9IA 4UN9A 3OOLA 3OORA 3MX9A 5E67A 3C0WA 4AAFA 1BP7A 5AKFA 3FD2A 5AK9A 4UN8A 2QOJZ 4UN7G 4AADA 5E5OA 2FLDA 1U0CA 1LWTA 2XE0A 4UNBA 1G9YA 5A74A 3E54A 3HYIA 5E63A 4YHXA 4Z1XA 5A0MA 1VDEA 3MXBB 2CW7A 4D6OA 3R7PA 5A72A 2F4LA 2I3QA 4AAEA 4AQUA 2VBNA 2VBLA 2CW8A 1N3FA 1AF5A 1MOWA 4YITA 1DFAA 4LOXA 2VBOA 2VBJA 4UNCA 4UN9G 5E5SA
chains in the Genus database with same CATH topology
2VS8A 3EH8A 2VBLB 4Z20A 1N3EA 1P8KZ 2XE0B 2VS7A 3KO2A 2VBJB 3HYJA 4UNAA 4UN8G 4EFJA 4Z1ZA 4UN7A 5AKMA 5A78A 1U0DA 4YISA 4AQXA 2AB5A 1DQ3A 5A0MB 1B24A 5AKNA 1EF0A 4LQ0A 1T9JA 5A77A 3MIPA 3MISA 1UM2A 3C0XA 2VBNB 3QQYA 2O7MA 2EX5A 3MXAA 4AABA 1G9ZA 2VBOB 1JVAA 5A0WA 2DCHX 4D6NA 4UT0A 1M5XA 1R7MA 4AAGA 2I3PA 1LWSA 3UVFA 3MXBA 1T9IA 4UN9A 3OOLA 3OORA 3MX9A 5E67A 3C0WA 4AAFA 1BP7A 5AKFA 3FD2A 5AK9A 4UN8A 2QOJZ 4UN7G 4AADA 5E5OA 2FLDA 1U0CA 1LWTA 2XE0A 4UNBA 1G9YA 5A74A 3E54A 3HYIA 5E63A 4YHXA 4Z1XA 5A0MA 1VDEA 3MXBB 2CW7A 4D6OA 3R7PA 5A72A 2I3QA 4AAEA 4AQUA 2VBNA 2VBLA 2CW8A 1N3FA 1AF5A 1MOWA 4YITA 1DFAA 4LOXA 2VBOA 2VBJA 4UNCA 4UN9G 5E5SA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VS8 A;  3EH8 A;  2VBL B;  4Z20 A;  1N3E A;  1P8K Z;  2XE0 B;  2VS7 A;  3KO2 A;  2VBJ B;  3HYJ A;  4UNA A;  4UN8 G;  4EFJ A;  4Z1Z A;  4UN7 A;  5AKM A;  5A78 A;  1U0D A;  4YIS A;  4AQX A;  2AB5 A;  1DQ3 A;  5A0M B;  1B24 A;  5AKN A;  1EF0 A;  4LQ0 A;  1T9J A;  5A77 A;  3MIP A;  3MIS A;  1UM2 A;  3C0X A;  2VBN B;  3QQY A;  2O7M A;  2EX5 A;  3MXA A;  4AAB A;  1G9Z A;  2VBO B;  1JVA A;  5A0W A;  2DCH X;  4D6N A;  4UT0 A;  1M5X A;  1R7M A;  4AAG A;  2I3P A;  1LWS A;  3UVF A;  3MXB A;  1T9I A;  4UN9 A;  3OOL A;  3OOR A;  3MX9 A;  5E67 A;  3C0W A;  4AAF A;  1BP7 A;  5AKF A;  3FD2 A;  5AK9 A;  4UN8 A;  2QOJ Z;  4UN7 G;  4AAD A;  5E5O A;  2FLD A;  1U0C A;  1LWT A;  2XE0 A;  4UNB A;  1G9Y A;  5A74 A;  3E54 A;  3HYI A;  5E63 A;  4YHX A;  4Z1X A;  5A0M A;  1VDE A;  3MXB B;  2CW7 A;  4D6O A;  3R7P A;  5A72 A;  2I3Q A;  4AAE A;  4AQU A;  2VBN A;  2VBL A;  2CW8 A;  1N3F A;  1AF5 A;  1MOW A;  4YIT A;  1DFA A;  4LOX A;  2VBO A;  2VBJ A;  4UNC A;  4UN9 G;  5E5S A; 
#chains in the Genus database with same CATH topology
 2VS8 A;  3EH8 A;  2VBL B;  4Z20 A;  1N3E A;  1P8K Z;  2XE0 B;  2VS7 A;  3KO2 A;  2VBJ B;  3HYJ A;  4UNA A;  4UN8 G;  4EFJ A;  4Z1Z A;  4UN7 A;  5AKM A;  5A78 A;  1U0D A;  4YIS A;  4AQX A;  2AB5 A;  1DQ3 A;  1B24 A;  5A0M B;  5AKN A;  1EF0 A;  4KZS A;  4LQ0 A;  1T9J A;  5A77 A;  3MIP A;  3MIS A;  1UM2 A;  3C0X A;  2VBN B;  3QQY A;  2O7M A;  2EX5 A;  3MXA A;  4AAB A;  1G9Z A;  2VBO B;  1JVA A;  5A0W A;  2DCH X;  4D6N A;  4UT0 A;  1M5X A;  1R7M A;  4AAG A;  2I3P A;  1LWS A;  3UVF A;  3MXB A;  1T9I A;  4UN9 A;  3OOL A;  3OOR A;  3MX9 A;  5E67 A;  3C0W A;  4AAF A;  1BP7 A;  5AKF A;  3FD2 A;  5AK9 A;  4UN8 A;  2QOJ Z;  4UN7 G;  4AAD A;  5E5O A;  2FLD A;  1U0C A;  1LWT A;  2XE0 A;  4UNB A;  1G9Y A;  5A74 A;  3E54 A;  3HYI A;  5E63 A;  4YHX A;  4Z1X A;  5A0M A;  1VDE A;  3MXB B;  2CW7 A;  4D6O A;  3R7P A;  5A72 A;  2F4L A;  2I3Q A;  4AAE A;  4AQU A;  2VBN A;  2VBL A;  2CW8 A;  1N3F A;  1AF5 A;  1MOW A;  4YIT A;  1DFA A;  4LOX A;  2VBO A;  2VBJ A;  4UNC A;  4UN9 G;  5E5S A; 
#chains in the Genus database with same CATH homology
 2VS8 A;  3EH8 A;  2VBL B;  4Z20 A;  1N3E A;  1P8K Z;  2XE0 B;  2VS7 A;  3KO2 A;  2VBJ B;  3HYJ A;  4UNA A;  4UN8 G;  4EFJ A;  4Z1Z A;  4UN7 A;  5AKM A;  5A78 A;  1U0D A;  4YIS A;  4AQX A;  2AB5 A;  1DQ3 A;  5A0M B;  1B24 A;  5AKN A;  1EF0 A;  4LQ0 A;  1T9J A;  5A77 A;  3MIP A;  3MIS A;  1UM2 A;  3C0X A;  2VBN B;  3QQY A;  2O7M A;  2EX5 A;  3MXA A;  4AAB A;  1G9Z A;  2VBO B;  1JVA A;  5A0W A;  2DCH X;  4D6N A;  4UT0 A;  1M5X A;  1R7M A;  4AAG A;  2I3P A;  1LWS A;  3UVF A;  3MXB A;  1T9I A;  4UN9 A;  3OOL A;  3OOR A;  3MX9 A;  5E67 A;  3C0W A;  4AAF A;  1BP7 A;  5AKF A;  3FD2 A;  5AK9 A;  4UN8 A;  2QOJ Z;  4UN7 G;  4AAD A;  5E5O A;  2FLD A;  1U0C A;  1LWT A;  2XE0 A;  4UNB A;  1G9Y A;  5A74 A;  3E54 A;  3HYI A;  5E63 A;  4YHX A;  4Z1X A;  5A0M A;  1VDE A;  3MXB B;  2CW7 A;  4D6O A;  3R7P A;  5A72 A;  2I3Q A;  4AAE A;  4AQU A;  2VBN A;  2VBL A;  2CW8 A;  1N3F A;  1AF5 A;  1MOW A;  4YIT A;  1DFA A;  4LOX A;  2VBO A;  2VBJ A;  4UNC A;  4UN9 G;  5E5S A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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