5AKF | Genus

Total Genus 56

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	56
sequence length	179
structure length	179
Chain Sequence	ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITAKSENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSSKKLYYYFANMLERIRLFNMREQIAFIKGLYVAEGDMTLKRLRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLNISLRDRIKFVHTILSSHLN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Desulfurococcus mobilis
publication title	Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold. pubmed doi rcsb
molecule keywords	HOMING ENDONUCLEASE I-DMOI
total genus	56
structure length	179
sequence length	179
chains with identical sequence	E, I
ec nomenclature	ec 3.1.-.-:
pdb deposition date	2015-03-03

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF14528	LAGLIDADG_3	LAGLIDADG-like domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.28.10	Alpha Beta	Roll	Endonuclease I-creI	Homing endonucleases	5akfA01
3.10.28.10	Alpha Beta	Roll	Endonuclease I-creI	Homing endonucleases	5akfA02

4Z1ZA 1VDEA 4UN9A 5AKMA 1U0CA 2I3QA 5AKFA 3OORA 5A72A 4YITA 2CW8A 2CW7A 1U0DA 2VBNA 4UN8G 4UNAA 5E63A 4YISA 2VBJB 5AKNA 2VS8A 1G9YA 5A78A 2VBLB 3MXBB 4AAGA 1DFAA 1B24A 4UN8A 5A0WA 3MISA 2VS7A 5A74A 3FD2A 1MOWA 3KO2A 2VBNB 4UNBA 4UN7G 5AK9A 1DQ3A 5A0MB 1P8KZ 3C0WA 4Z1XA 3C0XA 4D6OA 4AAEA 2VBOA 1M5XA 4EFJA 3UVFA 4UN7A 5A77A 3MXAA 4D6NA 4UNCA 1JVAA 1LWTA 4LOXA 1N3FA 4YHXA 3R7PA 1R7MA 1G9ZA 1AF5A 1EF0A 1T9JA 2VBOB 5E5OA 4AADA 2EX5A 1N3EA 2O7MA 4UN9G 4AABA 2DCHX 2VBJA 2XE0A 4Z20A 4LQ0A 4AAFA 4UT0A 3E54A 2VBLA 3MXBA 1T9IA 2I3PA 3MX9A 3HYIA 4AQXA 3HYJA 5E5SA 4AQUA 1BP7A 5A0MA 2QOJZ 2XE0B 3EH8A 5E67A 3MIPA 2AB5A 1UM2A 3QQYA 2FLDA 3OOLA 1LWSA
chains in the Genus database with same CATH superfamily

4Z1ZA 1VDEA 4UN9A 5AKMA 1U0CA 2I3QA 5AKFA 3OORA 5A72A 4YITA 2CW8A 2CW7A 1U0DA 2VBNA 4UN8G 4UNAA 5E63A 4YISA 2VBJB 5AKNA 2VS8A 2F4LA 1G9YA 5A78A 2VBLB 3MXBB 4AAGA 1DFAA 1B24A 4UN8A 5A0WA 3MISA 2VS7A 5A74A 3FD2A 1MOWA 3KO2A 2VBNB 4UNBA 4UN7G 5AK9A 1DQ3A 5A0MB 1P8KZ 3C0WA 4Z1XA 3C0XA 4D6OA 4KZSA 4AAEA 2VBOA 1M5XA 4EFJA 3UVFA 4UN7A 5A77A 3MXAA 4D6NA 4UNCA 1JVAA 1LWTA 4LOXA 1N3FA 4YHXA 3R7PA 1R7MA 1G9ZA 1AF5A 1EF0A 1T9JA 2VBOB 5E5OA 4AADA 2EX5A 1N3EA 2O7MA 4UN9G 4AABA 2DCHX 2VBJA 2XE0A 4Z20A 4LQ0A 4AAFA 4UT0A 3E54A 2VBLA 3MXBA 1T9IA 2I3PA 3MX9A 3HYIA 4AQXA 3HYJA 5E5SA 4AQUA 1BP7A 5A0MA 2QOJZ 2XE0B 3EH8A 5E67A 3MIPA 2AB5A 1UM2A 3QQYA 2FLDA 3OOLA 1LWSA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4Z1Z A;  1VDE A;  4UN9 A;  5AKM A;  1U0C A;  2I3Q A;  5AKF A;  3OOR A;  5A72 A;  4YIT A;  2CW8 A;  2CW7 A;  1U0D A;  2VBN A;  4UN8 G;  4UNA A;  5E63 A;  4YIS A;  2VBJ B;  5AKN A;  2VS8 A;  1G9Y A;  5A78 A;  2VBL B;  3MXB B;  4AAG A;  1DFA A;  1B24 A;  4UN8 A;  5A0W A;  3MIS A;  2VS7 A;  5A74 A;  3FD2 A;  1MOW A;  3KO2 A;  2VBN B;  4UNB A;  4UN7 G;  5AK9 A;  1DQ3 A;  5A0M B;  1P8K Z;  3C0W A;  4Z1X A;  3C0X A;  4D6O A;  4AAE A;  2VBO A;  1M5X A;  4EFJ A;  3UVF A;  4UN7 A;  5A77 A;  3MXA A;  4D6N A;  4UNC A;  1JVA A;  1LWT A;  4LOX A;  1N3F A;  4YHX A;  3R7P A;  1R7M A;  1G9Z A;  1AF5 A;  1EF0 A;  1T9J A;  2VBO B;  5E5O A;  4AAD A;  2EX5 A;  1N3E A;  2O7M A;  4UN9 G;  4AAB A;  2DCH X;  2VBJ A;  2XE0 A;  4Z20 A;  4LQ0 A;  4AAF A;  4UT0 A;  3E54 A;  2VBL A;  3MXB A;  1T9I A;  2I3P A;  3MX9 A;  3HYI A;  4AQX A;  3HYJ A;  5E5S A;  4AQU A;  1BP7 A;  5A0M A;  2QOJ Z;  2XE0 B;  3EH8 A;  5E67 A;  3MIP A;  2AB5 A;  1UM2 A;  3QQY A;  2FLD A;  3OOL A;  1LWS A; 
#chains in the Genus database with same CATH topology
 4Z1Z A;  1VDE A;  4UN9 A;  5AKM A;  1U0C A;  2I3Q A;  5AKF A;  3OOR A;  5A72 A;  4YIT A;  2CW8 A;  2CW7 A;  1U0D A;  2VBN A;  4UN8 G;  4UNA A;  5E63 A;  4YIS A;  2VBJ B;  5AKN A;  2VS8 A;  2F4L A;  1G9Y A;  5A78 A;  2VBL B;  3MXB B;  4AAG A;  1DFA A;  1B24 A;  4UN8 A;  5A0W A;  3MIS A;  2VS7 A;  5A74 A;  3FD2 A;  1MOW A;  3KO2 A;  2VBN B;  4UNB A;  4UN7 G;  5AK9 A;  1DQ3 A;  5A0M B;  1P8K Z;  3C0W A;  4Z1X A;  3C0X A;  4D6O A;  4KZS A;  4AAE A;  2VBO A;  1M5X A;  4EFJ A;  3UVF A;  4UN7 A;  5A77 A;  3MXA A;  4D6N A;  4UNC A;  1JVA A;  1LWT A;  4LOX A;  1N3F A;  4YHX A;  3R7P A;  1R7M A;  1G9Z A;  1AF5 A;  1EF0 A;  1T9J A;  2VBO B;  5E5O A;  4AAD A;  2EX5 A;  1N3E A;  2O7M A;  4UN9 G;  4AAB A;  2DCH X;  2VBJ A;  2XE0 A;  4Z20 A;  4LQ0 A;  4AAF A;  4UT0 A;  3E54 A;  2VBL A;  3MXB A;  1T9I A;  2I3P A;  3MX9 A;  3HYI A;  4AQX A;  3HYJ A;  5E5S A;  4AQU A;  1BP7 A;  5A0M A;  2QOJ Z;  2XE0 B;  3EH8 A;  5E67 A;  3MIP A;  2AB5 A;  1UM2 A;  3QQY A;  2FLD A;  3OOL A;  1LWS A; 
#chains in the Genus database with same CATH homology
 4Z1Z A;  1VDE A;  4UN9 A;  5AKM A;  1U0C A;  2I3Q A;  5AKF A;  3OOR A;  5A72 A;  4YIT A;  2CW8 A;  2CW7 A;  1U0D A;  2VBN A;  4UN8 G;  4UNA A;  5E63 A;  4YIS A;  2VBJ B;  5AKN A;  2VS8 A;  1G9Y A;  5A78 A;  2VBL B;  3MXB B;  4AAG A;  1DFA A;  1B24 A;  4UN8 A;  5A0W A;  3MIS A;  2VS7 A;  5A74 A;  3FD2 A;  1MOW A;  3KO2 A;  2VBN B;  4UNB A;  4UN7 G;  5AK9 A;  1DQ3 A;  5A0M B;  1P8K Z;  3C0W A;  4Z1X A;  3C0X A;  4D6O A;  4AAE A;  2VBO A;  1M5X A;  4EFJ A;  3UVF A;  4UN7 A;  5A77 A;  3MXA A;  4D6N A;  4UNC A;  1JVA A;  1LWT A;  4LOX A;  1N3F A;  4YHX A;  3R7P A;  1R7M A;  1G9Z A;  1AF5 A;  1EF0 A;  1T9J A;  2VBO B;  5E5O A;  4AAD A;  2EX5 A;  1N3E A;  2O7M A;  4UN9 G;  4AAB A;  2DCH X;  2VBJ A;  2XE0 A;  4Z20 A;  4LQ0 A;  4AAF A;  4UT0 A;  3E54 A;  2VBL A;  3MXB A;  1T9I A;  2I3P A;  3MX9 A;  3HYI A;  4AQX A;  3HYJ A;  5E5S A;  4AQU A;  1BP7 A;  5A0M A;  2QOJ Z;  2XE0 B;  3EH8 A;  5E67 A;  3MIP A;  2AB5 A;  1UM2 A;  3QQY A;  2FLD A;  3OOL A;  1LWS A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5AKFA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations