5E5SA

I-smami k103a mutant
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
297
structure length
297
Chain Sequence
ENSKLNPWAVVGFIDAEGSFMVRVRKNSKYKTGWLVVAIFSVTVDKKDLFLLESLKTFFGGLGSIKKSGNSTFSYRIESSEQLTKIILPFFDKYSLITEALGDYLLFKKVLELMGTKEHLTQRGLEKIVSLKASINKGLSEELQAAFPQCVPTPRPEINNKNIPDPFWLAGFVSGDGSFKSILKKSESIKVGFQSILVFQITQHARDVKLMESLISYLGCGFIEKDSRGPWLYYTVTNFSDIQGKIIPFFHQYKIIGSKYGDYQDWCKIALIMQNKNHLTPEGLNEIRALKGGMNKG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.
pubmed doi rcsb
molecule tags Hydrolase/dna
source organism Sordaria macrospora (strain atcc mya-333 / dsm 997 / k(l3346) / k-hell)
molecule keywords I-SmaMI LAGLIDADG meganuclease
total genus 92
structure length 297
sequence length 297
ec nomenclature
pdb deposition date 2015-10-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00961 LAGLIDADG_1 LAGLIDADG endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5e5sA01
3.10.28.10 Alpha Beta Roll Endonuclease I-creI Homing endonucleases 5e5sA02
1VDEA 3R7PA 3MISA 4UN9G 2FLDA 5AKNA 4EFJA 5AK9A 5E63A 2DCHX 4Z1ZA 4UN9A 3C0XA 5AKFA 2VBJB 3E54A 3FD2A 1MOWA 4UNBA 1G9ZA 1R7MA 1LWTA 1N3EA 2XE0A 1M5XA 4YHXA 3MX9A 1T9IA 2CW8A 3MIPA 5A74A 1B24A 3HYJA 5A78A 3UVFA 1P8KZ 2XE0B 1N3FA 2EX5A 5A0MA 3EH8A 4AAGA 4D6NA 5E5SA 4AAFA 1UM2A 2VS8A 3HYIA 5A0MB 4UN8G 3MXAA 4UN7G 2QOJZ 1BP7A 2AB5A 5E67A 2I3QA 4AABA 3OORA 4UN8A 4UN7A 2VBNA 4YITA 4AQXA 4UT0A 4D6OA 2VS7A 1AF5A 5A0WA 3KO2A 1DFAA 5AKMA 4UNCA 2VBNB 2VBOA 1U0DA 1U0CA 2VBLA 5E5OA 2O7MA 4AQUA 4AADA 1LWSA 4LQ0A 2VBOB 1T9JA 4Z1XA 2VBJA 5A77A 4Z20A 2VBLB 4AAEA 2I3PA 4LOXA 1JVAA 3MXBA 5A72A 1EF0A 4YISA 1G9YA 3C0WA 3OOLA 2CW7A 3QQYA 1DQ3A 4UNAA 3MXBB
chains in the Genus database with same CATH superfamily
1VDEA 4KZSA 3MISA 3R7PA 4UN9G 2FLDA 5AKNA 4EFJA 5AK9A 5E63A 2DCHX 4Z1ZA 4UN9A 3C0XA 5AKFA 2VBJB 3E54A 3FD2A 1MOWA 4UNBA 1G9ZA 1R7MA 1LWTA 1N3EA 2XE0A 1M5XA 4YHXA 3MX9A 1T9IA 2CW8A 3MIPA 5A74A 1B24A 3HYJA 5A78A 3UVFA 1P8KZ 2XE0B 1N3FA 2EX5A 5A0MA 3EH8A 4AAGA 4D6NA 5E5SA 4AAFA 1UM2A 2VS8A 3HYIA 5A0MB 4UN8G 3MXAA 4UN7G 2QOJZ 1BP7A 2AB5A 5E67A 2I3QA 4AABA 3OORA 4UN8A 4UN7A 2VBNA 4YITA 4AQXA 4UT0A 4D6OA 2VS7A 1AF5A 5A0WA 3KO2A 1DFAA 5AKMA 4UNCA 2VBNB 2VBOA 1U0DA 1U0CA 2VBLA 5E5OA 2O7MA 4AQUA 4AADA 1LWSA 4LQ0A 2VBOB 1T9JA 4Z1XA 2VBJA 5A77A 4Z20A 2VBLB 2F4LA 4AAEA 2I3PA 4LOXA 1JVAA 3MXBA 5A72A 1EF0A 4YISA 1G9YA 3C0WA 3OOLA 2CW7A 3QQYA 1DQ3A 4UNAA 3MXBB
chains in the Genus database with same CATH topology
1VDEA 3R7PA 3MISA 4UN9G 2FLDA 5AKNA 4EFJA 5AK9A 5E63A 2DCHX 4Z1ZA 4UN9A 3C0XA 5AKFA 2VBJB 3E54A 3FD2A 1MOWA 4UNBA 1G9ZA 1R7MA 1LWTA 1N3EA 2XE0A 1M5XA 4YHXA 3MX9A 1T9IA 2CW8A 3MIPA 5A74A 1B24A 3HYJA 5A78A 3UVFA 1P8KZ 2XE0B 1N3FA 2EX5A 5A0MA 3EH8A 4AAGA 4D6NA 5E5SA 4AAFA 1UM2A 2VS8A 3HYIA 5A0MB 4UN8G 3MXAA 4UN7G 2QOJZ 1BP7A 2AB5A 5E67A 2I3QA 4AABA 3OORA 4UN8A 4UN7A 2VBNA 4YITA 4AQXA 4UT0A 4D6OA 2VS7A 1AF5A 5A0WA 3KO2A 1DFAA 5AKMA 4UNCA 2VBNB 2VBOA 1U0DA 1U0CA 2VBLA 5E5OA 2O7MA 4AQUA 4AADA 1LWSA 4LQ0A 2VBOB 1T9JA 4Z1XA 2VBJA 5A77A 4Z20A 2VBLB 4AAEA 2I3PA 4LOXA 1JVAA 3MXBA 5A72A 1EF0A 4YISA 1G9YA 3C0WA 3OOLA 2CW7A 3QQYA 1DQ3A 4UNAA 3MXBB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1VDE A;  3R7P A;  3MIS A;  4UN9 G;  2FLD A;  5AKN A;  4EFJ A;  5AK9 A;  5E63 A;  2DCH X;  4Z1Z A;  4UN9 A;  3C0X A;  5AKF A;  2VBJ B;  3E54 A;  3FD2 A;  1MOW A;  4UNB A;  1G9Z A;  1R7M A;  1LWT A;  1N3E A;  2XE0 A;  1M5X A;  4YHX A;  3MX9 A;  1T9I A;  2CW8 A;  3MIP A;  5A74 A;  1B24 A;  3HYJ A;  5A78 A;  3UVF A;  1P8K Z;  2XE0 B;  1N3F A;  2EX5 A;  5A0M A;  3EH8 A;  4AAG A;  4D6N A;  5E5S A;  4AAF A;  1UM2 A;  2VS8 A;  3HYI A;  5A0M B;  4UN8 G;  3MXA A;  4UN7 G;  2QOJ Z;  1BP7 A;  2AB5 A;  5E67 A;  2I3Q A;  4AAB A;  3OOR A;  4UN8 A;  4UN7 A;  2VBN A;  4YIT A;  4AQX A;  4UT0 A;  4D6O A;  2VS7 A;  1AF5 A;  5A0W A;  3KO2 A;  1DFA A;  5AKM A;  4UNC A;  2VBN B;  2VBO A;  1U0D A;  1U0C A;  2VBL A;  5E5O A;  2O7M A;  4AQU A;  4AAD A;  1LWS A;  4LQ0 A;  2VBO B;  1T9J A;  4Z1X A;  2VBJ A;  5A77 A;  4Z20 A;  2VBL B;  4AAE A;  2I3P A;  4LOX A;  1JVA A;  3MXB A;  5A72 A;  1EF0 A;  4YIS A;  1G9Y A;  3C0W A;  3OOL A;  2CW7 A;  3QQY A;  1DQ3 A;  4UNA A;  3MXB B; 
#chains in the Genus database with same CATH topology
 1VDE A;  4KZS A;  3MIS A;  3R7P A;  4UN9 G;  2FLD A;  5AKN A;  4EFJ A;  5AK9 A;  5E63 A;  2DCH X;  4Z1Z A;  4UN9 A;  3C0X A;  5AKF A;  2VBJ B;  3E54 A;  3FD2 A;  1MOW A;  4UNB A;  1G9Z A;  1R7M A;  1LWT A;  1N3E A;  2XE0 A;  1M5X A;  4YHX A;  3MX9 A;  1T9I A;  2CW8 A;  3MIP A;  5A74 A;  1B24 A;  3HYJ A;  5A78 A;  3UVF A;  1P8K Z;  2XE0 B;  1N3F A;  2EX5 A;  5A0M A;  3EH8 A;  4AAG A;  4D6N A;  5E5S A;  4AAF A;  1UM2 A;  2VS8 A;  3HYI A;  5A0M B;  4UN8 G;  3MXA A;  4UN7 G;  2QOJ Z;  1BP7 A;  2AB5 A;  5E67 A;  2I3Q A;  4AAB A;  3OOR A;  4UN8 A;  4UN7 A;  2VBN A;  4YIT A;  4AQX A;  4UT0 A;  4D6O A;  2VS7 A;  1AF5 A;  5A0W A;  3KO2 A;  1DFA A;  5AKM A;  4UNC A;  2VBN B;  2VBO A;  1U0D A;  1U0C A;  2VBL A;  5E5O A;  2O7M A;  4AQU A;  4AAD A;  1LWS A;  4LQ0 A;  2VBO B;  1T9J A;  4Z1X A;  2VBJ A;  5A77 A;  4Z20 A;  2VBL B;  2F4L A;  4AAE A;  2I3P A;  4LOX A;  1JVA A;  3MXB A;  5A72 A;  1EF0 A;  4YIS A;  1G9Y A;  3C0W A;  3OOL A;  2CW7 A;  3QQY A;  1DQ3 A;  4UNA A;  3MXB B; 
#chains in the Genus database with same CATH homology
 1VDE A;  3R7P A;  3MIS A;  4UN9 G;  2FLD A;  5AKN A;  4EFJ A;  5AK9 A;  5E63 A;  2DCH X;  4Z1Z A;  4UN9 A;  3C0X A;  5AKF A;  2VBJ B;  3E54 A;  3FD2 A;  1MOW A;  4UNB A;  1G9Z A;  1R7M A;  1LWT A;  1N3E A;  2XE0 A;  1M5X A;  4YHX A;  3MX9 A;  1T9I A;  2CW8 A;  3MIP A;  5A74 A;  1B24 A;  3HYJ A;  5A78 A;  3UVF A;  1P8K Z;  2XE0 B;  1N3F A;  2EX5 A;  5A0M A;  3EH8 A;  4AAG A;  4D6N A;  5E5S A;  4AAF A;  1UM2 A;  2VS8 A;  3HYI A;  5A0M B;  4UN8 G;  3MXA A;  4UN7 G;  2QOJ Z;  1BP7 A;  2AB5 A;  5E67 A;  2I3Q A;  4AAB A;  3OOR A;  4UN8 A;  4UN7 A;  2VBN A;  4YIT A;  4AQX A;  4UT0 A;  4D6O A;  2VS7 A;  1AF5 A;  5A0W A;  3KO2 A;  1DFA A;  5AKM A;  4UNC A;  2VBN B;  2VBO A;  1U0D A;  1U0C A;  2VBL A;  5E5O A;  2O7M A;  4AQU A;  4AAD A;  1LWS A;  4LQ0 A;  2VBO B;  1T9J A;  4Z1X A;  2VBJ A;  5A77 A;  4Z20 A;  2VBL B;  4AAE A;  2I3P A;  4LOX A;  1JVA A;  3MXB A;  5A72 A;  1EF0 A;  4YIS A;  1G9Y A;  3C0W A;  3OOL A;  2CW7 A;  3QQY A;  1DQ3 A;  4UNA A;  3MXB B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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