5C5QA

Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
161
structure length
161
Chain Sequence
GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 47
structure length 161
sequence length 161
chains with identical sequence B
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-06-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 5c5qA00
4L7UA 3CE0A 3PAXA 4UVWA 5LX6A 4UI5A 4BUEA 5EBTA 4BJ9A 3SMIA 3KCZA 4L0VA 4MT9A 4R5WA 4BUWA 3GEYA 5LYHA 4N4VA 4PNLA 4R6EA 4BS4A 3HKVA 4L6SA 4TORA 4PNRA 3KR8A 4BUUA 3GJWA 4J3MA 3U9YA 5ADQA 3P0QA 1PAXA 4TOSA 3L3LA 3UH2A 4MSGA 4J3LA 4N3RA 4L2FA 4U6AA 1GS0A 2RCWA 4UVOA 5AL2A 4BUYA 4TKIA 4HYFA 1UK0A 4N4TA 4TKFA 3P0NA 3W51A 4L2KA 4OA7A 4UVSA 4OQAC 3UA9A 3SE2A 4TK5A 5ADTA 4J1ZA 4PNTA 4UI6A 5C5RA 4L32A 5C5QA 4UVZA 1A26A 4X52A 4BUFA 3GOYA 3MHJA 3SMJA 4W5IA 4KRSA 3C49A 4HKNA 4L0BA 4KZQA 4DQYC 4HHZA 4PNQA 4PAXA 3C4HA 4LI7A 4KZUA 3GN7A 4UX4A 4AVWA 5AL1A 3P0PA 3UDDA 4OQBC 4UFYA 5ECEA 4PMLA 4PNMA 4BJCA 4UI4A 5AL3A 3KJDA 4HLFA 2X5YA 4K4FA 4ZZXA 4HMHA 4L7NA 4BUAA 4PNNA 5AL4A 4BU5A 4KZLA 4UI3A 3MHKA 4IUEA 4BU9A 1WOKA 4M7BA 4BFPA 4F1QA 5LXPA 4L10A 4GV0A 4XHUA 4L33A 4DVIA 4TJWA 4W5SA 4TVJA 4UVNA 4K4EA 4HLMA 4LI6A 5ADRA 4UVPA 5AL5A 5ETYA 3BLJA 4HLKA 4L6ZA 4UVLA 4TK0A 4L0SA 4UI7A 4PY4A 4F0EA 4L09A 4BU3A 4F1LA 4OPXC 3UH4A 5A00A 4HLHA 4UFUA 4UI8A 1UK1A 4L7LA 4BJBA 5FPFA 3KR7A 2PAXA 3FHBA 4UXBA 4L7PA 4UVUA 5DCZA 4PNSA 4MSKA 5AKUA 4GV7A 5AEHA 2PQFA 4L70A 4BUIA 4BUSA 5C5PA 4UNDA 4L7RA 4RV6A 3L3MA 2RF5A 4GV2A 4J22A 4L31A 4ZZYA 3U9HA 4BUTA 4L34A 4TJYA 4TJUA 1EFYA 4GV4A 4BUXA 4L7OA 2PAWA 4L0TA 4BUDA 4HL5A 4UVVA 4I9IA 4HKIA 4PJTA 4UW1A 4BU7A 4BU6A 4BUVA 4TKGA 4HLGA 4W6EA 4AVUA 4L0IA 5ADSA 4HKKA 4L2GA 4UUHA 4LI8A 4PJVA 4UVYA 5FPGA 4BU8A 2RD6A 5AKWA 4UHGA 4UVTA 4HHYA 4J21A 4UVXA 4ZZZA
chains in the Genus database with same CATH superfamily
4L7UA 3CE0A 3PAXA 4UVWA 5LX6A 3MOFA 4UI5A 4WIEA 4YW8A 4BUEA 3MOEA 5EBTA 4BJ9A 3SMIA 3KCZA 1KHFA 4GMMA 4GMUA 4L0VA 4MT9A 3GEYA 4R5WA 4N4VA 4BUWA 4GMWA 4PNLA 4R6EA 4BS4A 3HKVA 4L6SA 4TORA 1KHEA 5FH2A 4PNRA 3KR8A 4BUUA 3GJWA 4J3MA 3U9YA 5ADQA 3P0QA 1PAXA 4TOSA 3L3LA 3UH2A 3DT4A 1KHBA 4WIUA 4MSGA 4J3LA 3MOHA 4L2FA 4GNPA 1GS0A 2RCWA 4N3RA 2GMVA 4U6AA 4UVOA 4BUYA 2QEYA 2RKDA 4TKIA 4HYFA 1UK0A 1XKVA 2RK8A 4N4TA 4TKFA 3P0NA 3W51A 4L2KA 4OA7A 4UVSA 4OQAC 3UA9A 3SE2A 5FH1A 2QZYA 4TK5A 5ADTA 5FH5A 4WPTA 2PC9A 4J1ZA 4PNTA 4UI6A 4YWDA 5I67A 5C5RA 4L32A 5C5QA 4UVZA 1A26A 4X52A 4BUFA 3GOYA 3DT2A 1K3CA 3MHJA 3SMJA 4W5IA 2OLRA 2RKEA 4KRSA 3C49A 4HKNA 4L0BA 4KZQA 4DQYC 4HHZA 4PNQA 2ZCIA 4PAXA 3C4HA 1YLHA 5FH0A 4WPUA 4LI7A 4KZUA 3GN7A 4UX4A 4R43A 1NHXA 4AVWA 1YVYA 5AL1A 3P0PA 3UDDA 2PXZX 4OQBC 4UFYA 5ECEA 4PMLA 3DTBA 4PNMA 4BJCA 4UI4A 4WL8A 5FH3A 5AL3A 3KJDA 4HLFA 1K3DA 2X5YA 4K4FA 4HMHA 4L7NA 4ZZXA 4BUAA 4PNNA 5AL4A 4BU5A 4KZLA 5AL2A 4UI3A 3MHKA 4IUEA 4BU9A 1WOKA 4M7BA 4BFPA 2PY7X 4F1QA 4YW9A 5LXPA 4GMZA 4L10A 2OLQA 2QEWA 4GV0A 4XHUA 5LYHA 1AYLA 4L33A 4DVIA 4J21A 4TJWA 4W5SA 4TVJA 4UVNA 4WPVA 4K4EA 4HLMA 4LI6A 5ADRA 4UVPA 5AL5A 5ETYA 3BLJA 4HLKA 4L6ZA 4UVLA 4GNOA 4TK0A 4L0SA 4UI7A 4PY4A 4F0EA 4GNQA 4L09A 5FH4A 4BU3A 4F1LA 4OX2A 3UH4A 4OPXC 5A00A 3DT7A 1II2A 4HLHA 4UFUA 1OS1A 4UI8A 1UK1A 4L7LA 4BJBA 5FPFA 3KR7A 2PAXA 3FHBA 4UXBA 1M51A 4L7PA 4UVUA 4GNLA 5DCZA 4PNSA 4MSKA 5AKUA 4GV7A 5AEHA 1KHGA 2PQFA 4L70A 4BUIA 4BUSA 5C5PA 4UNDA 4L7RA 4RV6A 3L3MA 2RF5A 4GV2A 4J22A 4L31A 4ZZYA 3U9HA 4BUTA 1AQ2A 4L34A 4TJYA 4TJUA 1EFYA 4GV4A 4BUXA 4L7OA 2PAWA 4L0TA 4BUDA 4HL5A 4UVVA 2QF1A 4HKIA 4I9IA 1YTMA 2FAFA 2QF2A 4PJTA 4UW1A 4BU7A 4BU6A 4BUVA 4TKGA 4HLGA 4W6EA 4AVUA 4L0IA 5ADSA 4HKKA 4YWBA 4L2GA 4RCGA 4UUHA 4LI8A 4PJVA 4UVYA 5FPGA 4BU8A 2RD6A 1YGGA 4GNMA 2RKAA 5AKWA 4UHGA 4WOUA 4UVTA 2FAHA 4HHYA 2RK7A 1J3BA 1OENA 4UVXA 4ZZZA
chains in the Genus database with same CATH topology
4L7UA 3CE0A 3PAXA 4UVWA 5LX6A 3MOFA 4UI5A 4WIEA 4YW8A 4BUEA 3MOEA 5EBTA 4BJ9A 3SMIA 3KCZA 1KHFA 4GMMA 4GMUA 4L0VA 4MT9A 3GEYA 4R5WA 4N4VA 4BUWA 4GMWA 4PNLA 4R6EA 4BS4A 3HKVA 4L6SA 4TORA 1KHEA 5FH2A 4PNRA 3KR8A 4BUUA 3GJWA 4J3MA 3U9YA 5ADQA 3P0QA 1PAXA 4TOSA 3L3LA 3UH2A 3DT4A 1KHBA 4WIUA 4MSGA 4J3LA 3MOHA 4L2FA 4GNPA 1GS0A 2RCWA 4N3RA 2GMVA 4U6AA 4UVOA 4BUYA 2QEYA 2RKDA 4TKIA 4HYFA 1UK0A 1XKVA 2RK8A 4N4TA 4TKFA 3P0NA 3W51A 4L2KA 4OA7A 4UVSA 4OQAC 3UA9A 3SE2A 5FH1A 2QZYA 4TK5A 5ADTA 5FH5A 4WPTA 2PC9A 4J1ZA 4PNTA 4UI6A 4YWDA 5I67A 5C5RA 4L32A 5C5QA 4UVZA 1A26A 4X52A 4BUFA 3GOYA 3DT2A 1K3CA 3MHJA 3SMJA 4W5IA 2OLRA 2RKEA 4KRSA 3C49A 4HKNA 4L0BA 4KZQA 4DQYC 4HHZA 4PNQA 2ZCIA 4PAXA 3C4HA 1YLHA 5FH0A 4WPUA 4LI7A 4KZUA 3GN7A 4UX4A 4R43A 1NHXA 4AVWA 1YVYA 5AL1A 3P0PA 3UDDA 2PXZX 4OQBC 4UFYA 5ECEA 4PMLA 3DTBA 4PNMA 4BJCA 4UI4A 4WL8A 5FH3A 5AL3A 3KJDA 4HLFA 1K3DA 2X5YA 4K4FA 4HMHA 4L7NA 4ZZXA 4BUAA 4PNNA 5AL4A 4BU5A 4KZLA 5AL2A 4UI3A 3MHKA 4IUEA 4BU9A 1WOKA 4M7BA 4BFPA 2PY7X 4F1QA 4YW9A 5LXPA 4GMZA 4L10A 2OLQA 2QEWA 4GV0A 4XHUA 5LYHA 1AYLA 4L33A 4DVIA 4J21A 4TJWA 4W5SA 4TVJA 4UVNA 4WPVA 4K4EA 4HLMA 4LI6A 5ADRA 4UVPA 5AL5A 5ETYA 3BLJA 4HLKA 4L6ZA 4UVLA 4GNOA 4TK0A 4L0SA 4UI7A 4PY4A 4F0EA 4GNQA 4L09A 5FH4A 4BU3A 4F1LA 4OX2A 3UH4A 4OPXC 5A00A 3DT7A 1II2A 4HLHA 4UFUA 1OS1A 4UI8A 1UK1A 4L7LA 4BJBA 5FPFA 3KR7A 2PAXA 3FHBA 4UXBA 1M51A 4L7PA 4UVUA 4GNLA 5DCZA 4PNSA 4MSKA 5AKUA 4GV7A 5AEHA 1KHGA 2PQFA 4L70A 4BUIA 4BUSA 5C5PA 4UNDA 4L7RA 4RV6A 3L3MA 2RF5A 4GV2A 4J22A 4L31A 4ZZYA 3U9HA 4BUTA 1AQ2A 4L34A 4TJYA 4TJUA 1EFYA 4GV4A 4BUXA 4L7OA 2PAWA 4L0TA 4BUDA 4HL5A 4UVVA 2QF1A 4HKIA 4I9IA 1YTMA 2FAFA 2QF2A 4PJTA 4UW1A 4BU7A 4BU6A 4BUVA 4TKGA 4HLGA 4W6EA 4AVUA 4L0IA 5ADSA 4HKKA 4YWBA 4L2GA 4RCGA 4UUHA 4LI8A 4PJVA 4UVYA 5FPGA 4BU8A 2RD6A 1YGGA 4GNMA 2RKAA 5AKWA 4UHGA 4WOUA 4UVTA 2FAHA 4HHYA 2RK7A 1J3BA 1OENA 4UVXA 4ZZZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L7U A;  3CE0 A;  3PAX A;  4UVW A;  5LX6 A;  4UI5 A;  4BUE A;  5EBT A;  4BJ9 A;  3SMI A;  3KCZ A;  4L0V A;  4MT9 A;  4R5W A;  4BUW A;  3GEY A;  5LYH A;  4N4V A;  4PNL A;  4R6E A;  4BS4 A;  3HKV A;  4L6S A;  4TOR A;  4PNR A;  3KR8 A;  4BUU A;  3GJW A;  4J3M A;  3U9Y A;  5ADQ A;  3P0Q A;  1PAX A;  4TOS A;  3L3L A;  3UH2 A;  4MSG A;  4J3L A;  4N3R A;  4L2F A;  4U6A A;  1GS0 A;  2RCW A;  4UVO A;  5AL2 A;  4BUY A;  4TKI A;  4HYF A;  1UK0 A;  4N4T A;  4TKF A;  3P0N A;  3W51 A;  4L2K A;  4OA7 A;  4UVS A;  4OQA C;  3UA9 A;  3SE2 A;  4TK5 A;  5ADT A;  4J1Z A;  4PNT A;  4UI6 A;  5C5R A;  4L32 A;  5C5Q A;  4UVZ A;  1A26 A;  4X52 A;  4BUF A;  3GOY A;  3MHJ A;  3SMJ A;  4W5I A;  4KRS A;  3C49 A;  4HKN A;  4L0B A;  4KZQ A;  4DQY C;  4HHZ A;  4PNQ A;  4PAX A;  3C4H A;  4LI7 A;  4KZU A;  3GN7 A;  4UX4 A;  4AVW A;  5AL1 A;  3P0P A;  3UDD A;  4OQB C;  4UFY A;  5ECE A;  4PML A;  4PNM A;  4BJC A;  4UI4 A;  5AL3 A;  3KJD A;  4HLF A;  2X5Y A;  4K4F A;  4ZZX A;  4HMH A;  4L7N A;  4BUA A;  4PNN A;  5AL4 A;  4BU5 A;  4KZL A;  4UI3 A;  3MHK A;  4IUE A;  4BU9 A;  1WOK A;  4M7B A;  4BFP A;  4F1Q A;  5LXP A;  4L10 A;  4GV0 A;  4XHU A;  4L33 A;  4DVI A;  4TJW A;  4W5S A;  4TVJ A;  4UVN A;  4K4E A;  4HLM A;  4LI6 A;  5ADR A;  4UVP A;  5AL5 A;  5ETY A;  3BLJ A;  4HLK A;  4L6Z A;  4UVL A;  4TK0 A;  4L0S A;  4UI7 A;  4PY4 A;  4F0E A;  4L09 A;  4BU3 A;  4F1L A;  4OPX C;  3UH4 A;  5A00 A;  4HLH A;  4UFU A;  4UI8 A;  1UK1 A;  4L7L A;  4BJB A;  5FPF A;  3KR7 A;  2PAX A;  3FHB A;  4UXB A;  4L7P A;  4UVU A;  5DCZ A;  4PNS A;  4MSK A;  5AKU A;  4GV7 A;  5AEH A;  2PQF A;  4L70 A;  4BUI A;  4BUS A;  5C5P A;  4UND A;  4L7R A;  4RV6 A;  3L3M A;  2RF5 A;  4GV2 A;  4J22 A;  4L31 A;  4ZZY A;  3U9H A;  4BUT A;  4L34 A;  4TJY A;  4TJU A;  1EFY A;  4GV4 A;  4BUX A;  4L7O A;  2PAW A;  4L0T A;  4BUD A;  4HL5 A;  4UVV A;  4I9I A;  4HKI A;  4PJT A;  4UW1 A;  4BU7 A;  4BU6 A;  4BUV A;  4TKG A;  4HLG A;  4W6E A;  4AVU A;  4L0I A;  5ADS A;  4HKK A;  4L2G A;  4UUH A;  4LI8 A;  4PJV A;  4UVY A;  5FPG A;  4BU8 A;  2RD6 A;  5AKW A;  4UHG A;  4UVT A;  4HHY A;  4J21 A;  4UVX A;  4ZZZ A; 
#chains in the Genus database with same CATH topology
 4L7U A;  3CE0 A;  3PAX A;  4UVW A;  5LX6 A;  3MOF A;  4UI5 A;  4WIE A;  4YW8 A;  4BUE A;  3MOE A;  5EBT A;  4BJ9 A;  3SMI A;  3KCZ A;  1KHF A;  4GMM A;  4GMU A;  4L0V A;  4MT9 A;  3GEY A;  4R5W A;  4N4V A;  4BUW A;  4GMW A;  4PNL A;  4R6E A;  4BS4 A;  3HKV A;  4L6S A;  4TOR A;  1KHE A;  5FH2 A;  4PNR A;  3KR8 A;  4BUU A;  3GJW A;  4J3M A;  3U9Y A;  5ADQ A;  3P0Q A;  1PAX A;  4TOS A;  3L3L A;  3UH2 A;  3DT4 A;  1KHB A;  4WIU A;  4MSG A;  4J3L A;  3MOH A;  4L2F A;  4GNP A;  1GS0 A;  2RCW A;  4N3R A;  2GMV A;  4U6A A;  4UVO A;  4BUY A;  2QEY A;  2RKD A;  4TKI A;  4HYF A;  1UK0 A;  1XKV A;  2RK8 A;  4N4T A;  4TKF A;  3P0N A;  3W51 A;  4L2K A;  4OA7 A;  4UVS A;  4OQA C;  3UA9 A;  3SE2 A;  5FH1 A;  2QZY A;  4TK5 A;  5ADT A;  5FH5 A;  4WPT A;  2PC9 A;  4J1Z A;  4PNT A;  4UI6 A;  4YWD A;  5I67 A;  5C5R A;  4L32 A;  5C5Q A;  4UVZ A;  1A26 A;  4X52 A;  4BUF A;  3GOY A;  3DT2 A;  1K3C A;  3MHJ A;  3SMJ A;  4W5I A;  2OLR A;  2RKE A;  4KRS A;  3C49 A;  4HKN A;  4L0B A;  4KZQ A;  4DQY C;  4HHZ A;  4PNQ A;  2ZCI A;  4PAX A;  3C4H A;  1YLH A;  5FH0 A;  4WPU A;  4LI7 A;  4KZU A;  3GN7 A;  4UX4 A;  4R43 A;  1NHX A;  4AVW A;  1YVY A;  5AL1 A;  3P0P A;  3UDD A;  2PXZ X;  4OQB C;  4UFY A;  5ECE A;  4PML A;  3DTB A;  4PNM A;  4BJC A;  4UI4 A;  4WL8 A;  5FH3 A;  5AL3 A;  3KJD A;  4HLF A;  1K3D A;  2X5Y A;  4K4F A;  4HMH A;  4L7N A;  4ZZX A;  4BUA A;  4PNN A;  5AL4 A;  4BU5 A;  4KZL A;  5AL2 A;  4UI3 A;  3MHK A;  4IUE A;  4BU9 A;  1WOK A;  4M7B A;  4BFP A;  2PY7 X;  4F1Q A;  4YW9 A;  5LXP A;  4GMZ A;  4L10 A;  2OLQ A;  2QEW A;  4GV0 A;  4XHU A;  5LYH A;  1AYL A;  4L33 A;  4DVI A;  4J21 A;  4TJW A;  4W5S A;  4TVJ A;  4UVN A;  4WPV A;  4K4E A;  4HLM A;  4LI6 A;  5ADR A;  4UVP A;  5AL5 A;  5ETY A;  3BLJ A;  4HLK A;  4L6Z A;  4UVL A;  4GNO A;  4TK0 A;  4L0S A;  4UI7 A;  4PY4 A;  4F0E A;  4GNQ A;  4L09 A;  5FH4 A;  4BU3 A;  4F1L A;  4OX2 A;  3UH4 A;  4OPX C;  5A00 A;  3DT7 A;  1II2 A;  4HLH A;  4UFU A;  1OS1 A;  4UI8 A;  1UK1 A;  4L7L A;  4BJB A;  5FPF A;  3KR7 A;  2PAX A;  3FHB A;  4UXB A;  1M51 A;  4L7P A;  4UVU A;  4GNL A;  5DCZ A;  4PNS A;  4MSK A;  5AKU A;  4GV7 A;  5AEH A;  1KHG A;  2PQF A;  4L70 A;  4BUI A;  4BUS A;  5C5P A;  4UND A;  4L7R A;  4RV6 A;  3L3M A;  2RF5 A;  4GV2 A;  4J22 A;  4L31 A;  4ZZY A;  3U9H A;  4BUT A;  1AQ2 A;  4L34 A;  4TJY A;  4TJU A;  1EFY A;  4GV4 A;  4BUX A;  4L7O A;  2PAW A;  4L0T A;  4BUD A;  4HL5 A;  4UVV A;  2QF1 A;  4HKI A;  4I9I A;  1YTM A;  2FAF A;  2QF2 A;  4PJT A;  4UW1 A;  4BU7 A;  4BU6 A;  4BUV A;  4TKG A;  4HLG A;  4W6E A;  4AVU A;  4L0I A;  5ADS A;  4HKK A;  4YWB A;  4L2G A;  4RCG A;  4UUH A;  4LI8 A;  4PJV A;  4UVY A;  5FPG A;  4BU8 A;  2RD6 A;  1YGG A;  4GNM A;  2RKA A;  5AKW A;  4UHG A;  4WOU A;  4UVT A;  2FAH A;  4HHY A;  2RK7 A;  1J3B A;  1OEN A;  4UVX A;  4ZZZ A; 
#chains in the Genus database with same CATH homology
 4L7U A;  3CE0 A;  3PAX A;  4UVW A;  5LX6 A;  3MOF A;  4UI5 A;  4WIE A;  4YW8 A;  4BUE A;  3MOE A;  5EBT A;  4BJ9 A;  3SMI A;  3KCZ A;  1KHF A;  4GMM A;  4GMU A;  4L0V A;  4MT9 A;  3GEY A;  4R5W A;  4N4V A;  4BUW A;  4GMW A;  4PNL A;  4R6E A;  4BS4 A;  3HKV A;  4L6S A;  4TOR A;  1KHE A;  5FH2 A;  4PNR A;  3KR8 A;  4BUU A;  3GJW A;  4J3M A;  3U9Y A;  5ADQ A;  3P0Q A;  1PAX A;  4TOS A;  3L3L A;  3UH2 A;  3DT4 A;  1KHB A;  4WIU A;  4MSG A;  4J3L A;  3MOH A;  4L2F A;  4GNP A;  1GS0 A;  2RCW A;  4N3R A;  2GMV A;  4U6A A;  4UVO A;  4BUY A;  2QEY A;  2RKD A;  4TKI A;  4HYF A;  1UK0 A;  1XKV A;  2RK8 A;  4N4T A;  4TKF A;  3P0N A;  3W51 A;  4L2K A;  4OA7 A;  4UVS A;  4OQA C;  3UA9 A;  3SE2 A;  5FH1 A;  2QZY A;  4TK5 A;  5ADT A;  5FH5 A;  4WPT A;  2PC9 A;  4J1Z A;  4PNT A;  4UI6 A;  4YWD A;  5I67 A;  5C5R A;  4L32 A;  5C5Q A;  4UVZ A;  1A26 A;  4X52 A;  4BUF A;  3GOY A;  3DT2 A;  1K3C A;  3MHJ A;  3SMJ A;  4W5I A;  2OLR A;  2RKE A;  4KRS A;  3C49 A;  4HKN A;  4L0B A;  4KZQ A;  4DQY C;  4HHZ A;  4PNQ A;  2ZCI A;  4PAX A;  3C4H A;  1YLH A;  5FH0 A;  4WPU A;  4LI7 A;  4KZU A;  3GN7 A;  4UX4 A;  4R43 A;  1NHX A;  4AVW A;  1YVY A;  5AL1 A;  3P0P A;  3UDD A;  2PXZ X;  4OQB C;  4UFY A;  5ECE A;  4PML A;  3DTB A;  4PNM A;  4BJC A;  4UI4 A;  4WL8 A;  5FH3 A;  5AL3 A;  3KJD A;  4HLF A;  1K3D A;  2X5Y A;  4K4F A;  4HMH A;  4L7N A;  4ZZX A;  4BUA A;  4PNN A;  5AL4 A;  4BU5 A;  4KZL A;  5AL2 A;  4UI3 A;  3MHK A;  4IUE A;  4BU9 A;  1WOK A;  4M7B A;  4BFP A;  2PY7 X;  4F1Q A;  4YW9 A;  5LXP A;  4GMZ A;  4L10 A;  2OLQ A;  2QEW A;  4GV0 A;  4XHU A;  5LYH A;  1AYL A;  4L33 A;  4DVI A;  4J21 A;  4TJW A;  4W5S A;  4TVJ A;  4UVN A;  4WPV A;  4K4E A;  4HLM A;  4LI6 A;  5ADR A;  4UVP A;  5AL5 A;  5ETY A;  3BLJ A;  4HLK A;  4L6Z A;  4UVL A;  4GNO A;  4TK0 A;  4L0S A;  4UI7 A;  4PY4 A;  4F0E A;  4GNQ A;  4L09 A;  5FH4 A;  4BU3 A;  4F1L A;  4OX2 A;  3UH4 A;  4OPX C;  5A00 A;  3DT7 A;  1II2 A;  4HLH A;  4UFU A;  1OS1 A;  4UI8 A;  1UK1 A;  4L7L A;  4BJB A;  5FPF A;  3KR7 A;  2PAX A;  3FHB A;  4UXB A;  1M51 A;  4L7P A;  4UVU A;  4GNL A;  5DCZ A;  4PNS A;  4MSK A;  5AKU A;  4GV7 A;  5AEH A;  1KHG A;  2PQF A;  4L70 A;  4BUI A;  4BUS A;  5C5P A;  4UND A;  4L7R A;  4RV6 A;  3L3M A;  2RF5 A;  4GV2 A;  4J22 A;  4L31 A;  4ZZY A;  3U9H A;  4BUT A;  1AQ2 A;  4L34 A;  4TJY A;  4TJU A;  1EFY A;  4GV4 A;  4BUX A;  4L7O A;  2PAW A;  4L0T A;  4BUD A;  4HL5 A;  4UVV A;  2QF1 A;  4HKI A;  4I9I A;  1YTM A;  2FAF A;  2QF2 A;  4PJT A;  4UW1 A;  4BU7 A;  4BU6 A;  4BUV A;  4TKG A;  4HLG A;  4W6E A;  4AVU A;  4L0I A;  5ADS A;  4HKK A;  4YWB A;  4L2G A;  4RCG A;  4UUH A;  4LI8 A;  4PJV A;  4UVY A;  5FPG A;  4BU8 A;  2RD6 A;  1YGG A;  4GNM A;  2RKA A;  5AKW A;  4UHG A;  4WOU A;  4UVT A;  2FAH A;  4HHY A;  2RK7 A;  1J3B A;  1OEN A;  4UVX A;  4ZZZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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