5C5RA

Crystal structure of human tankyrase-2 in complex with a pyranopyridone inhibitor
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
161
structure length
161
Chain Sequence
GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNRYNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFHGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFSA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Tankyrase-2
total genus 48
structure length 161
sequence length 161
chains with identical sequence B
ec nomenclature ec 2.4.2.30: NAD(+) ADP-ribosyltransferase.
pdb deposition date 2015-06-21
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.228.10 Alpha Beta Alpha-Beta Complex Phosphoenolpyruvate Carboxykinase; domain 3 Phosphoenolpyruvate Carboxykinase; domain 3 5c5rA00
4PNTA 4L7LA 4J21A 5ECEA 5LX6A 4UI3A 5AEHA 4BFPA 5AKUA 5LXPA 4W5SA 5C5RA 4UVXA 3KR8A 4ZZXA 4TKFA 4UFYA 3C49A 4UVOA 4UW1A 4N4TA 4TORA 3FHBA 4GV0A 4M7BA 4K4FA 1UK0A 4BUYA 4TJYA 3SMJA 4BUDA 4PNQA 4BU5A 4L7RA 4ZZYA 4KZUA 4PNLA 4J1ZA 5AL1A 4PMLA 4BUSA 4ZZZA 5FPGA 2X5YA 5ADTA 4LI7A 5AL2A 5C5PA 4PNRA 4HYFA 5ADQA 4UI4A 4GV2A 4L0BA 3HKVA 4L2GA 2PAWA 4BUFA 5LYHA 4UHGA 2RD6A 3BLJA 4L33A 4TOSA 3U9HA 5C5QA 4MSGA 4L7OA 4BUXA 4J22A 4BUIA 4UVLA 4HKKA 3C4HA 3KJDA 4F0EA 3GJWA 3GEYA 1UK1A 4BUWA 3GOYA 4L0IA 4L7PA 4UXBA 4KRSA 5A00A 4BUVA 3PAXA 4OQAC 2RCWA 3UA9A 4UI5A 4BUTA 3P0QA 3P0PA 4TKGA 3L3MA 5EBTA 4UFUA 4W6EA 4AVWA 5AL5A 4UVUA 2RF5A 4UNDA 4L2FA 5FPFA 4R5WA 4R6EA 4OQBC 4PNSA 4HLFA 4KZLA 4LI8A 4I9IA 4L70A 3MHJA 4BU3A 4BS4A 4UVVA 4UVTA 3UH2A 4TJWA 5AL3A 4L0VA 4BUUA 4TK0A 4HL5A 4UVNA 4J3LA 3UH4A 4UVSA 4DVIA 3MHKA 4OA7A 1A26A 2PAXA 4HHZA 3KCZA 4J3MA 3KR7A 4XHUA 4TK5A 4UUHA 4GV7A 3UDDA 4IUEA 4BU7A 5AL4A 4LI6A 4L32A 4L7UA 4RV6A 4PNMA 4HLHA 4GV4A 1WOKA 2PQFA 3L3LA 4UI8A 3U9YA 4HLMA 3W51A 1PAXA 4L2KA 4BJ9A 4BU9A 4L0SA 4MT9A 4BJBA 4HKIA 4K4EA 4UVYA 3CE0A 5AKWA 4UVWA 4TKIA 4UVPA 4N3RA 4TJUA 4L09A 1EFYA 4UI7A 4BJCA 4HLGA 3GN7A 4UVZA 4DQYC 3P0NA 4BU6A 4BUEA 4PJTA 4PJVA 4HHYA 4L6SA 4PNNA 4L34A 4N4VA 4PAXA 4U6AA 4PY4A 4X52A 4HMHA 4BUAA 4MSKA 4UX4A 4TVJA 3SMIA 4UI6A 5DCZA 4HKNA 4AVUA 5ADSA 4L7NA 4L0TA 5ETYA 3SE2A 4W5IA 4F1LA 4OPXC 4F1QA 1GS0A 4L31A 4BU8A 4KZQA 5ADRA 4L10A 4HLKA 4L6ZA
chains in the Genus database with same CATH superfamily
4PNTA 5FH2A 4L7LA 4J21A 5ECEA 5LX6A 4UI3A 2QF1A 5AEHA 5AKUA 4BFPA 4W5SA 5LXPA 5C5RA 2QF2A 4UVXA 3KR8A 1NHXA 4TKFA 4UFYA 3C49A 4GNPA 4OX2A 4N4TA 4TORA 3FHBA 4UVOA 4UW1A 1OS1A 4GMZA 4GV0A 4M7BA 4K4FA 1UK0A 4BUYA 4R43A 4TJYA 3SMJA 4BUDA 4PNQA 4BU5A 4L7RA 4ZZYA 3MOHA 4KZUA 1KHBA 4J1ZA 4PNLA 5AL1A 4PMLA 4BUSA 4ZZZA 5FPGA 2OLRA 2X5YA 5ADTA 4LI7A 5AL2A 1II2A 5C5PA 2PC9A 4PNRA 4HYFA 5ADQA 4UI4A 1OENA 4GV2A 3MOEA 4GMUA 4L0BA 3HKVA 1J3BA 4L2GA 2PAWA 4BUFA 5LYHA 4UHGA 2RD6A 3BLJA 4L33A 4TOSA 3U9HA 4WIEA 5C5QA 4MSGA 4L7OA 4BUXA 4J22A 4BUIA 1M51A 4UVLA 5FH3A 3C4HA 3KJDA 4F0EA 3GJWA 3GEYA 1UK1A 4WPUA 3GOYA 4L0IA 4L7PA 4BUWA 4UXBA 2OLQA 3DT7A 4KRSA 5A00A 4BUVA 3PAXA 4OQAC 2RCWA 4WIUA 4UI5A 3UA9A 4BUTA 3P0QA 5I67A 3P0PA 1XKVA 1K3CA 4TKGA 3L3MA 5EBTA 4UFUA 4W6EA 4AVWA 5AL5A 4UVUA 2RF5A 4UNDA 4L2FA 5FPFA 1KHFA 2QEWA 4GNLA 4R5WA 4R6EA 4OQBC 2RKDA 4PNSA 2QZYA 4HLFA 4KZLA 4I9IA 4LI8A 4YW8A 1YGGA 4L70A 2RK8A 2GMVA 3MHJA 4BU3A 4BS4A 4UVVA 4GNQA 1KHEA 4UVTA 3UH2A 4TJWA 5AL3A 4L0VA 5FH1A 4YWDA 4BUUA 4TK0A 2RK7A 4GMWA 4HL5A 4UVNA 4J3LA 3UH4A 4UVSA 4DVIA 3MHKA 4OA7A 4GNMA 1A26A 2PAXA 4HHZA 5FH0A 3KCZA 4J3MA 3KR7A 1AYLA 4XHUA 4TK5A 4UUHA 4GV7A 4WOUA 3UDDA 4WL8A 4IUEA 4BU7A 5AL4A 3DT4A 4L32A 4L7UA 4LI6A 4RV6A 4PNMA 4HLHA 2ZCIA 4GV4A 2FAFA 4YW9A 1WOKA 2PQFA 1K3DA 3L3LA 4UI8A 4HLMA 1YLHA 1YVYA 3U9YA 1PAXA 4L2KA 3W51A 4BJ9A 4BU9A 4L0SA 4MT9A 4BJBA 3DT2A 4HKIA 2FAHA 4K4EA 4UVYA 3MOFA 3CE0A 4WPVA 5AKWA 4UVWA 1AQ2A 4TKIA 4UVPA 4N3RA 4TJUA 4L09A 1EFYA 2PY7X 1YTMA 2PXZX 3GN7A 4HLGA 4UI7A 3P0NA 4UVZA 4BJCA 4DQYC 4BU6A 4BUEA 4L10A 4PJTA 4YWBA 4PJVA 4HHYA 4L6SA 4PNNA 2RKAA 5FH5A 4L34A 4N4VA 4GNOA 4PAXA 4WPTA 3DTBA 2QEYA 4U6AA 4PY4A 4X52A 4HMHA 4BUAA 4MSKA 4UX4A 4TVJA 3SMIA 4UI6A 5DCZA 4HKNA 4AVUA 2RKEA 4L7NA 5ADSA 4L0TA 5ETYA 3SE2A 5FH4A 4ZZXA 4GMMA 4W5IA 4F1LA 4OPXC 4F1QA 4RCGA 1GS0A 4L31A 1KHGA 4BU8A 4KZQA 5ADRA 4HKKA 4HLKA 4L6ZA
chains in the Genus database with same CATH topology
4PNTA 5FH2A 4L7LA 4J21A 5ECEA 5LX6A 4UI3A 2QF1A 5AEHA 5AKUA 4BFPA 4W5SA 5LXPA 5C5RA 2QF2A 4UVXA 3KR8A 1NHXA 4TKFA 4UFYA 3C49A 4GNPA 4OX2A 4N4TA 4TORA 3FHBA 4UVOA 4UW1A 1OS1A 4GMZA 4GV0A 4M7BA 4K4FA 1UK0A 4BUYA 4R43A 4TJYA 3SMJA 4BUDA 4PNQA 4BU5A 4L7RA 4ZZYA 3MOHA 4KZUA 1KHBA 4J1ZA 4PNLA 5AL1A 4PMLA 4BUSA 4ZZZA 5FPGA 2OLRA 2X5YA 5ADTA 4LI7A 5AL2A 1II2A 5C5PA 2PC9A 4PNRA 4HYFA 5ADQA 4UI4A 1OENA 4GV2A 3MOEA 4GMUA 4L0BA 3HKVA 1J3BA 4L2GA 2PAWA 4BUFA 5LYHA 4UHGA 2RD6A 3BLJA 4L33A 4TOSA 3U9HA 4WIEA 5C5QA 4MSGA 4L7OA 4BUXA 4J22A 4BUIA 1M51A 4UVLA 5FH3A 3C4HA 3KJDA 4F0EA 3GJWA 3GEYA 1UK1A 4WPUA 3GOYA 4L0IA 4L7PA 4BUWA 4UXBA 2OLQA 3DT7A 4KRSA 5A00A 4BUVA 3PAXA 4OQAC 2RCWA 4WIUA 4UI5A 3UA9A 4BUTA 3P0QA 5I67A 3P0PA 1XKVA 1K3CA 4TKGA 3L3MA 5EBTA 4UFUA 4W6EA 4AVWA 5AL5A 4UVUA 2RF5A 4UNDA 4L2FA 5FPFA 1KHFA 2QEWA 4GNLA 4R5WA 4R6EA 4OQBC 2RKDA 4PNSA 2QZYA 4HLFA 4KZLA 4I9IA 4LI8A 4YW8A 1YGGA 4L70A 2RK8A 2GMVA 3MHJA 4BU3A 4BS4A 4UVVA 4GNQA 1KHEA 4UVTA 3UH2A 4TJWA 5AL3A 4L0VA 5FH1A 4YWDA 4BUUA 4TK0A 2RK7A 4GMWA 4HL5A 4UVNA 4J3LA 3UH4A 4UVSA 4DVIA 3MHKA 4OA7A 4GNMA 1A26A 2PAXA 4HHZA 5FH0A 3KCZA 4J3MA 3KR7A 1AYLA 4XHUA 4TK5A 4UUHA 4GV7A 4WOUA 3UDDA 4WL8A 4IUEA 4BU7A 5AL4A 3DT4A 4L32A 4L7UA 4LI6A 4RV6A 4PNMA 4HLHA 2ZCIA 4GV4A 2FAFA 4YW9A 1WOKA 2PQFA 1K3DA 3L3LA 4UI8A 4HLMA 1YLHA 1YVYA 3U9YA 1PAXA 4L2KA 3W51A 4BJ9A 4BU9A 4L0SA 4MT9A 4BJBA 3DT2A 4HKIA 2FAHA 4K4EA 4UVYA 3MOFA 3CE0A 4WPVA 5AKWA 4UVWA 1AQ2A 4TKIA 4UVPA 4N3RA 4TJUA 4L09A 1EFYA 2PY7X 1YTMA 2PXZX 3GN7A 4HLGA 4UI7A 3P0NA 4UVZA 4BJCA 4DQYC 4BU6A 4BUEA 4L10A 4PJTA 4YWBA 4PJVA 4HHYA 4L6SA 4PNNA 2RKAA 5FH5A 4L34A 4N4VA 4GNOA 4PAXA 4WPTA 3DTBA 2QEYA 4U6AA 4PY4A 4X52A 4HMHA 4BUAA 4MSKA 4UX4A 4TVJA 3SMIA 4UI6A 5DCZA 4HKNA 4AVUA 2RKEA 4L7NA 5ADSA 4L0TA 5ETYA 3SE2A 5FH4A 4ZZXA 4GMMA 4W5IA 4F1LA 4OPXC 4F1QA 4RCGA 1GS0A 4L31A 1KHGA 4BU8A 4KZQA 5ADRA 4HKKA 4HLKA 4L6ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PNT A;  4L7L A;  4J21 A;  5ECE A;  5LX6 A;  4UI3 A;  5AEH A;  4BFP A;  5AKU A;  5LXP A;  4W5S A;  5C5R A;  4UVX A;  3KR8 A;  4ZZX A;  4TKF A;  4UFY A;  3C49 A;  4UVO A;  4UW1 A;  4N4T A;  4TOR A;  3FHB A;  4GV0 A;  4M7B A;  4K4F A;  1UK0 A;  4BUY A;  4TJY A;  3SMJ A;  4BUD A;  4PNQ A;  4BU5 A;  4L7R A;  4ZZY A;  4KZU A;  4PNL A;  4J1Z A;  5AL1 A;  4PML A;  4BUS A;  4ZZZ A;  5FPG A;  2X5Y A;  5ADT A;  4LI7 A;  5AL2 A;  5C5P A;  4PNR A;  4HYF A;  5ADQ A;  4UI4 A;  4GV2 A;  4L0B A;  3HKV A;  4L2G A;  2PAW A;  4BUF A;  5LYH A;  4UHG A;  2RD6 A;  3BLJ A;  4L33 A;  4TOS A;  3U9H A;  5C5Q A;  4MSG A;  4L7O A;  4BUX A;  4J22 A;  4BUI A;  4UVL A;  4HKK A;  3C4H A;  3KJD A;  4F0E A;  3GJW A;  3GEY A;  1UK1 A;  4BUW A;  3GOY A;  4L0I A;  4L7P A;  4UXB A;  4KRS A;  5A00 A;  4BUV A;  3PAX A;  4OQA C;  2RCW A;  3UA9 A;  4UI5 A;  4BUT A;  3P0Q A;  3P0P A;  4TKG A;  3L3M A;  5EBT A;  4UFU A;  4W6E A;  4AVW A;  5AL5 A;  4UVU A;  2RF5 A;  4UND A;  4L2F A;  5FPF A;  4R5W A;  4R6E A;  4OQB C;  4PNS A;  4HLF A;  4KZL A;  4LI8 A;  4I9I A;  4L70 A;  3MHJ A;  4BU3 A;  4BS4 A;  4UVV A;  4UVT A;  3UH2 A;  4TJW A;  5AL3 A;  4L0V A;  4BUU A;  4TK0 A;  4HL5 A;  4UVN A;  4J3L A;  3UH4 A;  4UVS A;  4DVI A;  3MHK A;  4OA7 A;  1A26 A;  2PAX A;  4HHZ A;  3KCZ A;  4J3M A;  3KR7 A;  4XHU A;  4TK5 A;  4UUH A;  4GV7 A;  3UDD A;  4IUE A;  4BU7 A;  5AL4 A;  4LI6 A;  4L32 A;  4L7U A;  4RV6 A;  4PNM A;  4HLH A;  4GV4 A;  1WOK A;  2PQF A;  3L3L A;  4UI8 A;  3U9Y A;  4HLM A;  3W51 A;  1PAX A;  4L2K A;  4BJ9 A;  4BU9 A;  4L0S A;  4MT9 A;  4BJB A;  4HKI A;  4K4E A;  4UVY A;  3CE0 A;  5AKW A;  4UVW A;  4TKI A;  4UVP A;  4N3R A;  4TJU A;  4L09 A;  1EFY A;  4UI7 A;  4BJC A;  4HLG A;  3GN7 A;  4UVZ A;  4DQY C;  3P0N A;  4BU6 A;  4BUE A;  4PJT A;  4PJV A;  4HHY A;  4L6S A;  4PNN A;  4L34 A;  4N4V A;  4PAX A;  4U6A A;  4PY4 A;  4X52 A;  4HMH A;  4BUA A;  4MSK A;  4UX4 A;  4TVJ A;  3SMI A;  4UI6 A;  5DCZ A;  4HKN A;  4AVU A;  5ADS A;  4L7N A;  4L0T A;  5ETY A;  3SE2 A;  4W5I A;  4F1L A;  4OPX C;  4F1Q A;  1GS0 A;  4L31 A;  4BU8 A;  4KZQ A;  5ADR A;  4L10 A;  4HLK A;  4L6Z A; 
#chains in the Genus database with same CATH topology
 4PNT A;  5FH2 A;  4L7L A;  4J21 A;  5ECE A;  5LX6 A;  4UI3 A;  2QF1 A;  5AEH A;  5AKU A;  4BFP A;  4W5S A;  5LXP A;  5C5R A;  2QF2 A;  4UVX A;  3KR8 A;  1NHX A;  4TKF A;  4UFY A;  3C49 A;  4GNP A;  4OX2 A;  4N4T A;  4TOR A;  3FHB A;  4UVO A;  4UW1 A;  1OS1 A;  4GMZ A;  4GV0 A;  4M7B A;  4K4F A;  1UK0 A;  4BUY A;  4R43 A;  4TJY A;  3SMJ A;  4BUD A;  4PNQ A;  4BU5 A;  4L7R A;  4ZZY A;  3MOH A;  4KZU A;  1KHB A;  4J1Z A;  4PNL A;  5AL1 A;  4PML A;  4BUS A;  4ZZZ A;  5FPG A;  2OLR A;  2X5Y A;  5ADT A;  4LI7 A;  5AL2 A;  1II2 A;  5C5P A;  2PC9 A;  4PNR A;  4HYF A;  5ADQ A;  4UI4 A;  1OEN A;  4GV2 A;  3MOE A;  4GMU A;  4L0B A;  3HKV A;  1J3B A;  4L2G A;  2PAW A;  4BUF A;  5LYH A;  4UHG A;  2RD6 A;  3BLJ A;  4L33 A;  4TOS A;  3U9H A;  4WIE A;  5C5Q A;  4MSG A;  4L7O A;  4BUX A;  4J22 A;  4BUI A;  1M51 A;  4UVL A;  5FH3 A;  3C4H A;  3KJD A;  4F0E A;  3GJW A;  3GEY A;  1UK1 A;  4WPU A;  3GOY A;  4L0I A;  4L7P A;  4BUW A;  4UXB A;  2OLQ A;  3DT7 A;  4KRS A;  5A00 A;  4BUV A;  3PAX A;  4OQA C;  2RCW A;  4WIU A;  4UI5 A;  3UA9 A;  4BUT A;  3P0Q A;  5I67 A;  3P0P A;  1XKV A;  1K3C A;  4TKG A;  3L3M A;  5EBT A;  4UFU A;  4W6E A;  4AVW A;  5AL5 A;  4UVU A;  2RF5 A;  4UND A;  4L2F A;  5FPF A;  1KHF A;  2QEW A;  4GNL A;  4R5W A;  4R6E A;  4OQB C;  2RKD A;  4PNS A;  2QZY A;  4HLF A;  4KZL A;  4I9I A;  4LI8 A;  4YW8 A;  1YGG A;  4L70 A;  2RK8 A;  2GMV A;  3MHJ A;  4BU3 A;  4BS4 A;  4UVV A;  4GNQ A;  1KHE A;  4UVT A;  3UH2 A;  4TJW A;  5AL3 A;  4L0V A;  5FH1 A;  4YWD A;  4BUU A;  4TK0 A;  2RK7 A;  4GMW A;  4HL5 A;  4UVN A;  4J3L A;  3UH4 A;  4UVS A;  4DVI A;  3MHK A;  4OA7 A;  4GNM A;  1A26 A;  2PAX A;  4HHZ A;  5FH0 A;  3KCZ A;  4J3M A;  3KR7 A;  1AYL A;  4XHU A;  4TK5 A;  4UUH A;  4GV7 A;  4WOU A;  3UDD A;  4WL8 A;  4IUE A;  4BU7 A;  5AL4 A;  3DT4 A;  4L32 A;  4L7U A;  4LI6 A;  4RV6 A;  4PNM A;  4HLH A;  2ZCI A;  4GV4 A;  2FAF A;  4YW9 A;  1WOK A;  2PQF A;  1K3D A;  3L3L A;  4UI8 A;  4HLM A;  1YLH A;  1YVY A;  3U9Y A;  1PAX A;  4L2K A;  3W51 A;  4BJ9 A;  4BU9 A;  4L0S A;  4MT9 A;  4BJB A;  3DT2 A;  4HKI A;  2FAH A;  4K4E A;  4UVY A;  3MOF A;  3CE0 A;  4WPV A;  5AKW A;  4UVW A;  1AQ2 A;  4TKI A;  4UVP A;  4N3R A;  4TJU A;  4L09 A;  1EFY A;  2PY7 X;  1YTM A;  2PXZ X;  3GN7 A;  4HLG A;  4UI7 A;  3P0N A;  4UVZ A;  4BJC A;  4DQY C;  4BU6 A;  4BUE A;  4L10 A;  4PJT A;  4YWB A;  4PJV A;  4HHY A;  4L6S A;  4PNN A;  2RKA A;  5FH5 A;  4L34 A;  4N4V A;  4GNO A;  4PAX A;  4WPT A;  3DTB A;  2QEY A;  4U6A A;  4PY4 A;  4X52 A;  4HMH A;  4BUA A;  4MSK A;  4UX4 A;  4TVJ A;  3SMI A;  4UI6 A;  5DCZ A;  4HKN A;  4AVU A;  2RKE A;  4L7N A;  5ADS A;  4L0T A;  5ETY A;  3SE2 A;  5FH4 A;  4ZZX A;  4GMM A;  4W5I A;  4F1L A;  4OPX C;  4F1Q A;  4RCG A;  1GS0 A;  4L31 A;  1KHG A;  4BU8 A;  4KZQ A;  5ADR A;  4HKK A;  4HLK A;  4L6Z A; 
#chains in the Genus database with same CATH homology
 4PNT A;  5FH2 A;  4L7L A;  4J21 A;  5ECE A;  5LX6 A;  4UI3 A;  2QF1 A;  5AEH A;  5AKU A;  4BFP A;  4W5S A;  5LXP A;  5C5R A;  2QF2 A;  4UVX A;  3KR8 A;  1NHX A;  4TKF A;  4UFY A;  3C49 A;  4GNP A;  4OX2 A;  4N4T A;  4TOR A;  3FHB A;  4UVO A;  4UW1 A;  1OS1 A;  4GMZ A;  4GV0 A;  4M7B A;  4K4F A;  1UK0 A;  4BUY A;  4R43 A;  4TJY A;  3SMJ A;  4BUD A;  4PNQ A;  4BU5 A;  4L7R A;  4ZZY A;  3MOH A;  4KZU A;  1KHB A;  4J1Z A;  4PNL A;  5AL1 A;  4PML A;  4BUS A;  4ZZZ A;  5FPG A;  2OLR A;  2X5Y A;  5ADT A;  4LI7 A;  5AL2 A;  1II2 A;  5C5P A;  2PC9 A;  4PNR A;  4HYF A;  5ADQ A;  4UI4 A;  1OEN A;  4GV2 A;  3MOE A;  4GMU A;  4L0B A;  3HKV A;  1J3B A;  4L2G A;  2PAW A;  4BUF A;  5LYH A;  4UHG A;  2RD6 A;  3BLJ A;  4L33 A;  4TOS A;  3U9H A;  4WIE A;  5C5Q A;  4MSG A;  4L7O A;  4BUX A;  4J22 A;  4BUI A;  1M51 A;  4UVL A;  5FH3 A;  3C4H A;  3KJD A;  4F0E A;  3GJW A;  3GEY A;  1UK1 A;  4WPU A;  3GOY A;  4L0I A;  4L7P A;  4BUW A;  4UXB A;  2OLQ A;  3DT7 A;  4KRS A;  5A00 A;  4BUV A;  3PAX A;  4OQA C;  2RCW A;  4WIU A;  4UI5 A;  3UA9 A;  4BUT A;  3P0Q A;  5I67 A;  3P0P A;  1XKV A;  1K3C A;  4TKG A;  3L3M A;  5EBT A;  4UFU A;  4W6E A;  4AVW A;  5AL5 A;  4UVU A;  2RF5 A;  4UND A;  4L2F A;  5FPF A;  1KHF A;  2QEW A;  4GNL A;  4R5W A;  4R6E A;  4OQB C;  2RKD A;  4PNS A;  2QZY A;  4HLF A;  4KZL A;  4I9I A;  4LI8 A;  4YW8 A;  1YGG A;  4L70 A;  2RK8 A;  2GMV A;  3MHJ A;  4BU3 A;  4BS4 A;  4UVV A;  4GNQ A;  1KHE A;  4UVT A;  3UH2 A;  4TJW A;  5AL3 A;  4L0V A;  5FH1 A;  4YWD A;  4BUU A;  4TK0 A;  2RK7 A;  4GMW A;  4HL5 A;  4UVN A;  4J3L A;  3UH4 A;  4UVS A;  4DVI A;  3MHK A;  4OA7 A;  4GNM A;  1A26 A;  2PAX A;  4HHZ A;  5FH0 A;  3KCZ A;  4J3M A;  3KR7 A;  1AYL A;  4XHU A;  4TK5 A;  4UUH A;  4GV7 A;  4WOU A;  3UDD A;  4WL8 A;  4IUE A;  4BU7 A;  5AL4 A;  3DT4 A;  4L32 A;  4L7U A;  4LI6 A;  4RV6 A;  4PNM A;  4HLH A;  2ZCI A;  4GV4 A;  2FAF A;  4YW9 A;  1WOK A;  2PQF A;  1K3D A;  3L3L A;  4UI8 A;  4HLM A;  1YLH A;  1YVY A;  3U9Y A;  1PAX A;  4L2K A;  3W51 A;  4BJ9 A;  4BU9 A;  4L0S A;  4MT9 A;  4BJB A;  3DT2 A;  4HKI A;  2FAH A;  4K4E A;  4UVY A;  3MOF A;  3CE0 A;  4WPV A;  5AKW A;  4UVW A;  1AQ2 A;  4TKI A;  4UVP A;  4N3R A;  4TJU A;  4L09 A;  1EFY A;  2PY7 X;  1YTM A;  2PXZ X;  3GN7 A;  4HLG A;  4UI7 A;  3P0N A;  4UVZ A;  4BJC A;  4DQY C;  4BU6 A;  4BUE A;  4L10 A;  4PJT A;  4YWB A;  4PJV A;  4HHY A;  4L6S A;  4PNN A;  2RKA A;  5FH5 A;  4L34 A;  4N4V A;  4GNO A;  4PAX A;  4WPT A;  3DTB A;  2QEY A;  4U6A A;  4PY4 A;  4X52 A;  4HMH A;  4BUA A;  4MSK A;  4UX4 A;  4TVJ A;  3SMI A;  4UI6 A;  5DCZ A;  4HKN A;  4AVU A;  2RKE A;  4L7N A;  5ADS A;  4L0T A;  5ETY A;  3SE2 A;  5FH4 A;  4ZZX A;  4GMM A;  4W5I A;  4F1L A;  4OPX C;  4F1Q A;  4RCG A;  1GS0 A;  4L31 A;  1KHG A;  4BU8 A;  4KZQ A;  5ADR A;  4HKK A;  4HLK A;  4L6Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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