1D5LC

Crystal structure of cyanide-bound human myeloperoxidase isoform c at ph 5.5
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
466
structure length
465
Chain Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWREA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords MYELOPEROXIDASE
total genus 143
structure length 465
sequence length 466
chains with identical sequence D
ec nomenclature ec 1.11.2.2: Myeloperoxidase.
pdb deposition date 1999-10-07
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.640.10 Mainly Alpha Orthogonal Bundle Myeloperoxidase, subunit C Haem peroxidase domain superfamily, animal type 1d5lC00
5F19A 6COXA 3NT1A 4RUTA 3Q7DA 3N8XA 3SXVA 3F9PC 4LJJA 2PUMA 2EHAA 5HPWA 3RKEA 3MQEA 3UBAA 1EQHA 1PXXA 3KRKA 4RRWA 5KIRA 3N8YB 4RS0A 4QYQA 3HS6A 5IKVA 4RRXA 4E1GA 3RR3A 5JVZA 3TZIA 4PNXA 1D2VC 3S4FA 2NQXA 1U67A 3GCJA 3QH0A 1Q4GA 3N8VA 4GN6A 3NAKA 3FNLA 5IKTA 1CVUA 3PY4A 2AYLA 2GJMA 2QRBA 5B72A 1FE2A 1EBVA 3NTBA 3HS5A 2OJVA 4GM7A 3OLTA 3N8FA 1PGEA 4RRYA 4OTYA 3GCLA 3OLUA 2EFBA 4OEKA 4OTJA 3R55A 4C1MC 4RRZA 4COXA 2E9EA 4KVLA 3QF1A 1D7WC 3PGHA 4NT3A 5JW1A 3I6NA 3V6QA 3R5OA 1CX2A 3R4XA 3NIUA 4M10A 1PRHA 4Z0LA 1DNWC 3HS7A 5GH0A 3NTGA 3TGYA 4KVJA 4NJBA 1EQGA 5FIWC 1IGZA 5IKRA 1IGXA 3NYHA 3KRQA 2IPSA 1DNUC 3QMOA 2IKCA 3Q9KA 3GC1A 1HT8A 1PTHA 2OYUP 3QL6A 4KSZA 3ERIA 5JVYA 1DDXA 4DL1C 3LN0A 5FF1A 4QJQA 3GCKA 2R5LA 4KVKA 2Z5ZA 3KK6A 3LN1A 4MSFA 5COXA 4Y55A 3R5QA 3MDLA 3ERHA 2OYEP 2PT3A 4FM5A 1DIYA 1HT5A 4O1ZA 3N8WA 1CXPC 4HHSA 1D5LC 3BXIA 4PH9A 1CQEA 1MYPC 4M11A 5IKQA 3OGWA 2QQTA 5FDQA 4IG5A 5F1AA 5GLSA 3FAQA 3ZS1C 2QPKA 3N8ZA 3ZS0C 2O86A 1MHLC 4N7AA 4HHRA 3N8WB 3N8YA
chains in the Genus database with same CATH superfamily
5F19A 6COXA 3NT1A 4RUTA 3Q7DA 3N8XA 3SXVA 3F9PC 4LJJA 2PUMA 2EHAA 5HPWA 3RKEA 3MQEA 3UBAA 1EQHA 1PXXA 3KRKA 4RRWA 5KIRA 3N8YB 4RS0A 4QYQA 3HS6A 5IKVA 4RRXA 4E1GA 3RR3A 5JVZA 3TZIA 4PNXA 1D2VC 3S4FA 2NQXA 1U67A 3GCJA 3QH0A 1Q4GA 3N8VA 4GN6A 3NAKA 3FNLA 5IKTA 1CVUA 3PY4A 2AYLA 2GJMA 2QRBA 5B72A 1FE2A 1EBVA 3NTBA 3HS5A 2OJVA 4GM7A 3OLTA 3N8FA 1PGEA 4RRYA 4OTYA 3GCLA 3OLUA 2EFBA 4OEKA 4OTJA 3R55A 4C1MC 4RRZA 4COXA 2E9EA 4KVLA 3QF1A 1D7WC 3PGHA 4NT3A 5JW1A 3I6NA 3V6QA 3R5OA 1CX2A 3R4XA 3NIUA 4M10A 1PRHA 4Z0LA 1DNWC 3HS7A 5GH0A 3NTGA 3TGYA 4KVJA 4NJBA 1EQGA 5FIWC 1IGZA 5IKRA 1IGXA 3NYHA 3KRQA 2IPSA 1DNUC 3QMOA 2IKCA 3Q9KA 3GC1A 1HT8A 1PTHA 2OYUP 3QL6A 4KSZA 3ERIA 5JVYA 1DDXA 4DL1C 3LN0A 5FF1A 4QJQA 3GCKA 2R5LA 4KVKA 2Z5ZA 3KK6A 3LN1A 4MSFA 5COXA 4Y55A 3R5QA 3MDLA 3ERHA 2OYEP 2PT3A 4FM5A 1DIYA 1HT5A 4O1ZA 3N8WA 1CXPC 4HHSA 1D5LC 3BXIA 4PH9A 1CQEA 1MYPC 4M11A 5IKQA 3OGWA 2QQTA 5FDQA 4IG5A 5F1AA 5GLSA 3FAQA 3ZS1C 2QPKA 3N8ZA 3ZS0C 2O86A 1MHLC 4N7AA 4HHRA 3N8WB 3N8YA
chains in the Genus database with same CATH topology
5F19A 6COXA 3NT1A 4RUTA 3Q7DA 3N8XA 3SXVA 3F9PC 4LJJA 2PUMA 2EHAA 5HPWA 3RKEA 3MQEA 3UBAA 1EQHA 1PXXA 3KRKA 4RRWA 5KIRA 3N8YB 4RS0A 4QYQA 3HS6A 5IKVA 4RRXA 4E1GA 3RR3A 5JVZA 3TZIA 4PNXA 1D2VC 3S4FA 2NQXA 1U67A 3GCJA 3QH0A 1Q4GA 3N8VA 4GN6A 3NAKA 3FNLA 5IKTA 1CVUA 3PY4A 2AYLA 2GJMA 2QRBA 5B72A 1FE2A 1EBVA 3NTBA 3HS5A 2OJVA 4GM7A 3OLTA 3N8FA 1PGEA 4RRYA 4OTYA 3GCLA 3OLUA 2EFBA 4OEKA 4OTJA 3R55A 4C1MC 4RRZA 4COXA 2E9EA 4KVLA 3QF1A 1D7WC 3PGHA 4NT3A 5JW1A 3I6NA 3V6QA 3R5OA 1CX2A 3R4XA 3NIUA 4M10A 1PRHA 4Z0LA 1DNWC 3HS7A 5GH0A 3NTGA 3TGYA 4KVJA 4NJBA 1EQGA 5FIWC 1IGZA 5IKRA 1IGXA 3NYHA 3KRQA 2IPSA 1DNUC 3QMOA 2IKCA 3Q9KA 3GC1A 1HT8A 1PTHA 2OYUP 3QL6A 4KSZA 3ERIA 5JVYA 1DDXA 4DL1C 3LN0A 5FF1A 4QJQA 3GCKA 2R5LA 4KVKA 2Z5ZA 3KK6A 3LN1A 4MSFA 5COXA 4Y55A 3R5QA 3MDLA 3ERHA 2OYEP 2PT3A 4FM5A 1DIYA 1HT5A 4O1ZA 3N8WA 1CXPC 4HHSA 1D5LC 3BXIA 4PH9A 1CQEA 1MYPC 4M11A 5IKQA 3OGWA 2QQTA 5FDQA 4IG5A 5F1AA 5GLSA 3FAQA 3ZS1C 2QPKA 3N8ZA 3ZS0C 2O86A 1MHLC 4N7AA 4HHRA 3N8WB 3N8YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5F19 A;  6COX A;  3NT1 A;  4RUT A;  3Q7D A;  3N8X A;  3SXV A;  3F9P C;  4LJJ A;  2PUM A;  2EHA A;  5HPW A;  3RKE A;  3MQE A;  3UBA A;  1EQH A;  1PXX A;  3KRK A;  4RRW A;  5KIR A;  3N8Y B;  4RS0 A;  4QYQ A;  3HS6 A;  5IKV A;  4RRX A;  4E1G A;  3RR3 A;  5JVZ A;  3TZI A;  4PNX A;  1D2V C;  3S4F A;  2NQX A;  1U67 A;  3GCJ A;  3QH0 A;  1Q4G A;  3N8V A;  4GN6 A;  3NAK A;  3FNL A;  5IKT A;  1CVU A;  3PY4 A;  2AYL A;  2GJM A;  2QRB A;  5B72 A;  1FE2 A;  1EBV A;  3NTB A;  3HS5 A;  2OJV A;  4GM7 A;  3OLT A;  3N8F A;  1PGE A;  4RRY A;  4OTY A;  3GCL A;  3OLU A;  2EFB A;  4OEK A;  4OTJ A;  3R55 A;  4C1M C;  4RRZ A;  4COX A;  2E9E A;  4KVL A;  3QF1 A;  1D7W C;  3PGH A;  4NT3 A;  5JW1 A;  3I6N A;  3V6Q A;  3R5O A;  1CX2 A;  3R4X A;  3NIU A;  4M10 A;  1PRH A;  4Z0L A;  1DNW C;  3HS7 A;  5GH0 A;  3NTG A;  3TGY A;  4KVJ A;  4NJB A;  1EQG A;  5FIW C;  1IGZ A;  5IKR A;  1IGX A;  3NYH A;  3KRQ A;  2IPS A;  1DNU C;  3QMO A;  2IKC A;  3Q9K A;  3GC1 A;  1HT8 A;  1PTH A;  2OYU P;  3QL6 A;  4KSZ A;  3ERI A;  5JVY A;  1DDX A;  4DL1 C;  3LN0 A;  5FF1 A;  4QJQ A;  3GCK A;  2R5L A;  4KVK A;  2Z5Z A;  3KK6 A;  3LN1 A;  4MSF A;  5COX A;  4Y55 A;  3R5Q A;  3MDL A;  3ERH A;  2OYE P;  2PT3 A;  4FM5 A;  1DIY A;  1HT5 A;  4O1Z A;  3N8W A;  1CXP C;  4HHS A;  1D5L C;  3BXI A;  4PH9 A;  1CQE A;  1MYP C;  4M11 A;  5IKQ A;  3OGW A;  2QQT A;  5FDQ A;  4IG5 A;  5F1A A;  5GLS A;  3FAQ A;  3ZS1 C;  2QPK A;  3N8Z A;  3ZS0 C;  2O86 A;  1MHL C;  4N7A A;  4HHR A;  3N8W B;  3N8Y A; 
#chains in the Genus database with same CATH topology
 5F19 A;  6COX A;  3NT1 A;  4RUT A;  3Q7D A;  3N8X A;  3SXV A;  3F9P C;  4LJJ A;  2PUM A;  2EHA A;  5HPW A;  3RKE A;  3MQE A;  3UBA A;  1EQH A;  1PXX A;  3KRK A;  4RRW A;  5KIR A;  3N8Y B;  4RS0 A;  4QYQ A;  3HS6 A;  5IKV A;  4RRX A;  4E1G A;  3RR3 A;  5JVZ A;  3TZI A;  4PNX A;  1D2V C;  3S4F A;  2NQX A;  1U67 A;  3GCJ A;  3QH0 A;  1Q4G A;  3N8V A;  4GN6 A;  3NAK A;  3FNL A;  5IKT A;  1CVU A;  3PY4 A;  2AYL A;  2GJM A;  2QRB A;  5B72 A;  1FE2 A;  1EBV A;  3NTB A;  3HS5 A;  2OJV A;  4GM7 A;  3OLT A;  3N8F A;  1PGE A;  4RRY A;  4OTY A;  3GCL A;  3OLU A;  2EFB A;  4OEK A;  4OTJ A;  3R55 A;  4C1M C;  4RRZ A;  4COX A;  2E9E A;  4KVL A;  3QF1 A;  1D7W C;  3PGH A;  4NT3 A;  5JW1 A;  3I6N A;  3V6Q A;  3R5O A;  1CX2 A;  3R4X A;  3NIU A;  4M10 A;  1PRH A;  4Z0L A;  1DNW C;  3HS7 A;  5GH0 A;  3NTG A;  3TGY A;  4KVJ A;  4NJB A;  1EQG A;  5FIW C;  1IGZ A;  5IKR A;  1IGX A;  3NYH A;  3KRQ A;  2IPS A;  1DNU C;  3QMO A;  2IKC A;  3Q9K A;  3GC1 A;  1HT8 A;  1PTH A;  2OYU P;  3QL6 A;  4KSZ A;  3ERI A;  5JVY A;  1DDX A;  4DL1 C;  3LN0 A;  5FF1 A;  4QJQ A;  3GCK A;  2R5L A;  4KVK A;  2Z5Z A;  3KK6 A;  3LN1 A;  4MSF A;  5COX A;  4Y55 A;  3R5Q A;  3MDL A;  3ERH A;  2OYE P;  2PT3 A;  4FM5 A;  1DIY A;  1HT5 A;  4O1Z A;  3N8W A;  1CXP C;  4HHS A;  1D5L C;  3BXI A;  4PH9 A;  1CQE A;  1MYP C;  4M11 A;  5IKQ A;  3OGW A;  2QQT A;  5FDQ A;  4IG5 A;  5F1A A;  5GLS A;  3FAQ A;  3ZS1 C;  2QPK A;  3N8Z A;  3ZS0 C;  2O86 A;  1MHL C;  4N7A A;  4HHR A;  3N8W B;  3N8Y A; 
#chains in the Genus database with same CATH homology
 5F19 A;  6COX A;  3NT1 A;  4RUT A;  3Q7D A;  3N8X A;  3SXV A;  3F9P C;  4LJJ A;  2PUM A;  2EHA A;  5HPW A;  3RKE A;  3MQE A;  3UBA A;  1EQH A;  1PXX A;  3KRK A;  4RRW A;  5KIR A;  3N8Y B;  4RS0 A;  4QYQ A;  3HS6 A;  5IKV A;  4RRX A;  4E1G A;  3RR3 A;  5JVZ A;  3TZI A;  4PNX A;  1D2V C;  3S4F A;  2NQX A;  1U67 A;  3GCJ A;  3QH0 A;  1Q4G A;  3N8V A;  4GN6 A;  3NAK A;  3FNL A;  5IKT A;  1CVU A;  3PY4 A;  2AYL A;  2GJM A;  2QRB A;  5B72 A;  1FE2 A;  1EBV A;  3NTB A;  3HS5 A;  2OJV A;  4GM7 A;  3OLT A;  3N8F A;  1PGE A;  4RRY A;  4OTY A;  3GCL A;  3OLU A;  2EFB A;  4OEK A;  4OTJ A;  3R55 A;  4C1M C;  4RRZ A;  4COX A;  2E9E A;  4KVL A;  3QF1 A;  1D7W C;  3PGH A;  4NT3 A;  5JW1 A;  3I6N A;  3V6Q A;  3R5O A;  1CX2 A;  3R4X A;  3NIU A;  4M10 A;  1PRH A;  4Z0L A;  1DNW C;  3HS7 A;  5GH0 A;  3NTG A;  3TGY A;  4KVJ A;  4NJB A;  1EQG A;  5FIW C;  1IGZ A;  5IKR A;  1IGX A;  3NYH A;  3KRQ A;  2IPS A;  1DNU C;  3QMO A;  2IKC A;  3Q9K A;  3GC1 A;  1HT8 A;  1PTH A;  2OYU P;  3QL6 A;  4KSZ A;  3ERI A;  5JVY A;  1DDX A;  4DL1 C;  3LN0 A;  5FF1 A;  4QJQ A;  3GCK A;  2R5L A;  4KVK A;  2Z5Z A;  3KK6 A;  3LN1 A;  4MSF A;  5COX A;  4Y55 A;  3R5Q A;  3MDL A;  3ERH A;  2OYE P;  2PT3 A;  4FM5 A;  1DIY A;  1HT5 A;  4O1Z A;  3N8W A;  1CXP C;  4HHS A;  1D5L C;  3BXI A;  4PH9 A;  1CQE A;  1MYP C;  4M11 A;  5IKQ A;  3OGW A;  2QQT A;  5FDQ A;  4IG5 A;  5F1A A;  5GLS A;  3FAQ A;  3ZS1 C;  2QPK A;  3N8Z A;  3ZS0 C;  2O86 A;  1MHL C;  4N7A A;  4HHR A;  3N8W B;  3N8Y A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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